WGS CADB00000000 data, contig 59

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial carrier protein, putative

Species:

Leishmania mexicana

UniProt:

E8NHL5_LEIMU

TriTrypDb:

LmxM.34.3330 , LmxM.34.3330a

Length:

362

Annotations

LeishMANIAdb annotations

Homologous to Eukaryotic mitochondrial and chloroplast transporters for folate or nicotinic acid. Has no canonical mitochondrial target signal, only a Leishmaniid-specific C-terminal extension. Localization: Mitochondrial (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

E8NHL5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHL5

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	12
GO:0006862	nucleotide transport	6	11
GO:0009987	cellular process	1	12
GO:0015748	organophosphate ester transport	5	11
GO:0015931	nucleobase-containing compound transport	5	11
GO:0051179	localization	1	12
GO:0051234	establishment of localization	2	12
GO:0055085	transmembrane transport	2	12
GO:0071702	organic substance transport	4	12
GO:0071705	nitrogen compound transport	4	12
GO:0006811	monoatomic ion transport	4	1
GO:0006820	monoatomic anion transport	5	1
GO:0006835	dicarboxylic acid transport	7	1
GO:0015711	organic anion transport	5	1
GO:0015849	organic acid transport	5	1
GO:0015884	folic acid transport	5	1
GO:0034220	monoatomic ion transmembrane transport	3	1
GO:0035461	vitamin transmembrane transport	3	1
GO:0042886	amide transport	5	1
GO:0046942	carboxylic acid transport	6	1
GO:0051180	vitamin transport	4	1
GO:0072337	modified amino acid transport	5	1
GO:0098656	monoatomic anion transmembrane transport	4	1
GO:0098838	folate transmembrane transport	4	1
GO:1903825	organic acid transmembrane transport	3	1
GO:1904947	folate import into mitochondrion	4	1
GO:1905039	carboxylic acid transmembrane transport	4	1
GO:1990542	mitochondrial transmembrane transport	3	1

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	1
GO:0005342	organic acid transmembrane transporter activity	3	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0008517	folic acid transmembrane transporter activity	4	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015215	nucleotide transmembrane transporter activity	4	1
GO:0015230	FAD transmembrane transporter activity	5	1
GO:0015605	organophosphate ester transmembrane transporter activity	3	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3	1
GO:0022857	transmembrane transporter activity	2	1
GO:0042887	amide transmembrane transporter activity	3	1
GO:0046943	carboxylic acid transmembrane transporter activity	4	1
GO:0072349	modified amino acid transmembrane transporter activity	3	1
GO:0090482	vitamin transmembrane transporter activity	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	150	152	PF00675	0.243
CLV_NRD_NRD_1	180	182	PF00675	0.325
CLV_NRD_NRD_1	212	214	PF00675	0.520
CLV_PCSK_KEX2_1	150	152	PF00082	0.243
CLV_PCSK_KEX2_1	180	182	PF00082	0.277
CLV_PCSK_KEX2_1	19	21	PF00082	0.513
CLV_PCSK_KEX2_1	212	214	PF00082	0.429
CLV_PCSK_PC1ET2_1	19	21	PF00082	0.513
CLV_PCSK_PC7_1	176	182	PF00082	0.301
CLV_PCSK_SKI1_1	185	189	PF00082	0.344
CLV_PCSK_SKI1_1	213	217	PF00082	0.461
CLV_PCSK_SKI1_1	264	268	PF00082	0.264
CLV_PCSK_SKI1_1	67	71	PF00082	0.293
CLV_Separin_Metazoa	246	250	PF03568	0.418
CLV_Separin_Metazoa	68	72	PF03568	0.433
DEG_SPOP_SBC_1	327	331	PF00917	0.515
DOC_CKS1_1	140	145	PF01111	0.271
DOC_CYCLIN_RxL_1	210	220	PF00134	0.241
DOC_MAPK_MEF2A_6	189	197	PF00069	0.444
DOC_PP4_FxxP_1	241	244	PF00568	0.160
DOC_USP7_MATH_1	167	171	PF00917	0.514
DOC_USP7_MATH_1	228	232	PF00917	0.275
DOC_USP7_MATH_1	327	331	PF00917	0.472
DOC_USP7_MATH_1	347	351	PF00917	0.568
DOC_USP7_MATH_1	62	66	PF00917	0.443
DOC_WW_Pin1_4	10	15	PF00397	0.358
DOC_WW_Pin1_4	139	144	PF00397	0.256
DOC_WW_Pin1_4	220	225	PF00397	0.425
DOC_WW_Pin1_4	3	8	PF00397	0.491
LIG_14-3-3_CanoR_1	312	316	PF00244	0.326
LIG_14-3-3_CanoR_1	50	55	PF00244	0.412
LIG_Actin_RPEL_3	178	197	PF02755	0.441
LIG_BIR_II_1	1	5	PF00653	0.345
LIG_BRCT_BRCA1_1	331	335	PF00533	0.411
LIG_deltaCOP1_diTrp_1	182	188	PF00928	0.466
LIG_deltaCOP1_diTrp_1	209	216	PF00928	0.320
LIG_EH1_1	25	33	PF00400	0.350
LIG_FHA_1	106	112	PF00498	0.424
LIG_FHA_1	135	141	PF00498	0.291
LIG_FHA_1	200	206	PF00498	0.316
LIG_FHA_1	316	322	PF00498	0.401
LIG_FHA_1	49	55	PF00498	0.446
LIG_FHA_2	112	118	PF00498	0.337
LIG_FHA_2	204	210	PF00498	0.311
LIG_FHA_2	215	221	PF00498	0.235
LIG_LIR_Gen_1	206	216	PF02991	0.314
LIG_LIR_Nem_3	170	175	PF02991	0.499
LIG_LIR_Nem_3	206	211	PF02991	0.282
LIG_LIR_Nem_3	90	96	PF02991	0.284
LIG_NRBOX	106	112	PF00104	0.254
LIG_PCNA_yPIPBox_3	101	111	PF02747	0.320
LIG_PCNA_yPIPBox_3	204	213	PF02747	0.399
LIG_PCNA_yPIPBox_3	67	79	PF02747	0.485
LIG_Pex14_1	184	188	PF04695	0.468
LIG_Pex14_2	188	192	PF04695	0.400
LIG_SH2_CRK	283	287	PF00017	0.429
LIG_SH2_CRK	79	83	PF00017	0.269
LIG_SH2_STAP1	304	308	PF00017	0.223
LIG_SH2_STAT5	96	99	PF00017	0.266
LIG_SH3_2	14	19	PF14604	0.345
LIG_SH3_3	11	17	PF00018	0.428
LIG_SH3_3	137	143	PF00018	0.316
LIG_SH3_3	353	359	PF00018	0.438
LIG_SUMO_SIM_par_1	82	88	PF11976	0.290
LIG_WRC_WIRS_1	97	102	PF05994	0.272
MOD_CK1_1	12	18	PF00069	0.529
MOD_CK1_1	231	237	PF00069	0.256
MOD_CK1_1	329	335	PF00069	0.530
MOD_CK1_1	345	351	PF00069	0.348
MOD_CK1_1	85	91	PF00069	0.310
MOD_CK2_1	115	121	PF00069	0.454
MOD_CK2_1	203	209	PF00069	0.290
MOD_CK2_1	214	220	PF00069	0.243
MOD_CK2_1	62	68	PF00069	0.505
MOD_GlcNHglycan	101	104	PF01048	0.482
MOD_GlcNHglycan	121	125	PF01048	0.536
MOD_GlcNHglycan	128	131	PF01048	0.321
MOD_GlcNHglycan	160	163	PF01048	0.347
MOD_GlcNHglycan	169	172	PF01048	0.281
MOD_GlcNHglycan	230	233	PF01048	0.262
MOD_GlcNHglycan	34	37	PF01048	0.402
MOD_GSK3_1	1	8	PF00069	0.491
MOD_GSK3_1	111	118	PF00069	0.305
MOD_GSK3_1	132	139	PF00069	0.457
MOD_GSK3_1	195	202	PF00069	0.288
MOD_GSK3_1	265	272	PF00069	0.479
MOD_GSK3_1	311	318	PF00069	0.381
MOD_GSK3_1	323	330	PF00069	0.404
MOD_GSK3_1	342	349	PF00069	0.408
MOD_GSK3_1	46	53	PF00069	0.460
MOD_N-GLC_1	199	204	PF02516	0.382
MOD_N-GLC_1	9	14	PF02516	0.630
MOD_NEK2_1	1	6	PF00069	0.444
MOD_NEK2_1	115	120	PF00069	0.459
MOD_NEK2_1	317	322	PF00069	0.389
MOD_NEK2_1	32	37	PF00069	0.268
MOD_NEK2_1	46	51	PF00069	0.400
MOD_NEK2_1	9	14	PF00069	0.496
MOD_NEK2_2	62	67	PF00069	0.350
MOD_NEK2_2	96	101	PF00069	0.290
MOD_PKA_2	105	111	PF00069	0.402
MOD_PKA_2	311	317	PF00069	0.387
MOD_PKB_1	48	56	PF00069	0.436
MOD_Plk_1	111	117	PF00069	0.440
MOD_Plk_1	199	205	PF00069	0.413
MOD_Plk_4	115	121	PF00069	0.384
MOD_Plk_4	136	142	PF00069	0.303
MOD_Plk_4	203	209	PF00069	0.318
MOD_Plk_4	269	275	PF00069	0.456
MOD_Plk_4	294	300	PF00069	0.274
MOD_Plk_4	82	88	PF00069	0.297
MOD_ProDKin_1	10	16	PF00069	0.357
MOD_ProDKin_1	139	145	PF00069	0.256
MOD_ProDKin_1	220	226	PF00069	0.320
MOD_ProDKin_1	3	9	PF00069	0.490
MOD_SUMO_for_1	18	21	PF00179	0.444
TRG_ENDOCYTIC_2	208	211	PF00928	0.218
TRG_ENDOCYTIC_2	263	266	PF00928	0.436
TRG_ENDOCYTIC_2	283	286	PF00928	0.358
TRG_ENDOCYTIC_2	304	307	PF00928	0.212
TRG_ENDOCYTIC_2	79	82	PF00928	0.256
TRG_ER_diArg_1	179	181	PF00400	0.525
TRG_ER_diArg_1	211	213	PF00400	0.320
TRG_ER_diArg_1	47	50	PF00400	0.429
TRG_Pf-PMV_PEXEL_1	151	155	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	189	194	PF00026	0.356

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K309	Rattus norvegicus	22%	100%
A0A0G2K5L2	Rattus norvegicus	25%	100%
A0A0N0P2Z6	Leptomonas seymouri	22%	100%
A0A0N0P4V4	Leptomonas seymouri	71%	100%
A0A0N0P7X0	Leptomonas seymouri	22%	100%
A0A0N0P7Y4	Leptomonas seymouri	21%	100%
A0A0N0P8W6	Leptomonas seymouri	24%	100%
A0A0N1I6I9	Leptomonas seymouri	28%	100%
A0A0N1IMP5	Leptomonas seymouri	27%	100%
A0A0N1PFJ3	Leptomonas seymouri	23%	100%
A0A0S4IV98	Bodo saltans	22%	100%
A0A0S4J045	Bodo saltans	24%	100%
A0A0S4J7Z5	Bodo saltans	23%	96%
A0A0S4J9F4	Bodo saltans	27%	100%
A0A0S4JHC1	Bodo saltans	47%	100%
A0A0S4JHF7	Bodo saltans	22%	100%
A0A0S4JQI3	Bodo saltans	24%	100%
A0A0S4JR63	Bodo saltans	23%	100%
A0A0S4KJX8	Bodo saltans	25%	100%
A0A0U2IR85	Ustilago maydis	25%	100%
A0A1D6N272	Zea mays	25%	100%
A0A1X0NFT4	Trypanosomatidae	23%	100%
A0A1X0NJD2	Trypanosomatidae	22%	100%
A0A1X0NN16	Trypanosomatidae	23%	100%
A0A1X0NTK9	Trypanosomatidae	24%	100%
A0A1X0NUM8	Trypanosomatidae	27%	100%
A0A1X0NUU7	Trypanosomatidae	30%	100%
A0A1X0P4Q9	Trypanosomatidae	25%	100%
A0A1X0P555	Trypanosomatidae	26%	100%
A0A1X0P6S2	Trypanosomatidae	55%	100%
A0A1X0P778	Trypanosomatidae	23%	100%
A0A1X0P952	Trypanosomatidae	25%	100%
A0A3Q8I9Y9	Leishmania donovani	26%	100%
A0A3Q8IFU6	Leishmania donovani	28%	100%
A0A3Q8IKX9	Leishmania donovani	27%	100%
A0A3R7KLL6	Trypanosoma rangeli	26%	100%
A0A3R7LCB2	Trypanosoma rangeli	29%	100%
A0A3R7M893	Trypanosoma rangeli	22%	100%
A0A3R7P246	Trypanosoma rangeli	26%	100%
A0A3R7RT89	Trypanosoma rangeli	22%	100%
A0A3S5H800	Leishmania donovani	89%	100%
A0A3S7WTS6	Leishmania donovani	23%	100%
A0A3S7WYS1	Leishmania donovani	23%	100%
A0A422N763	Trypanosoma rangeli	50%	100%
A0A422NF39	Trypanosoma rangeli	23%	100%
A0A422NSB9	Trypanosoma rangeli	25%	100%
A0JN87	Bos taurus	24%	100%
A1CIF6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	23%	100%
A1CWA4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	24%	100%
A1DI57	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	25%	100%
A2ASZ8	Mus musculus	25%	77%
A2CEQ0	Danio rerio	27%	77%
A2Q9F0	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	100%
A2R5A0	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	100%
A3LVX1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	24%	100%
A3M019	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	21%	100%
A4H7Y2	Leishmania braziliensis	25%	100%
A4H8E6	Leishmania braziliensis	21%	100%
A4HDW8	Leishmania braziliensis	21%	100%
A4HHT5	Leishmania braziliensis	26%	100%
A4HI60	Leishmania braziliensis	24%	100%
A4HK93	Leishmania braziliensis	25%	100%
A4HK94	Leishmania braziliensis	27%	100%
A4HN00	Leishmania braziliensis	80%	100%
A4HWA9	Leishmania infantum	26%	100%
A4HWR9	Leishmania infantum	23%	100%
A4I163	Leishmania infantum	23%	100%
A4I7S8	Leishmania infantum	27%	100%
A4I7S9	Leishmania infantum	28%	100%
A4IBM3	Leishmania infantum	88%	100%
A4QNX2	Danio rerio	27%	100%
A4RF23	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	30%	100%
A4RPU0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	27%	100%
A5D9W9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	24%	100%
A5DIS9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	23%	100%
A5DX39	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	24%	100%
A5PJZ1	Bos taurus	24%	76%
A6RAY2	Ajellomyces capsulatus (strain NAm1 / WU24)	25%	100%
A6RF73	Ajellomyces capsulatus (strain NAm1 / WU24)	25%	100%
A6SL61	Botryotinia fuckeliana (strain B05.10)	24%	100%
A6ZV78	Saccharomyces cerevisiae (strain YJM789)	24%	100%
A7A285	Saccharomyces cerevisiae (strain YJM789)	23%	100%
A7ER02	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	25%	100%
A7TIQ0	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	23%	100%
B0DK57	Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686)	23%	100%
B0G143	Dictyostelium discoideum	25%	100%
B0G159	Dictyostelium discoideum	23%	77%
B0Y4J4	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	23%	100%
B2MVX9	Ovis aries	24%	100%
B2VSU4	Pyrenophora tritici-repentis (strain Pt-1C-BFP)	21%	100%
B3LUQ6	Saccharomyces cerevisiae (strain RM11-1a)	22%	100%
B4F8I5	Zea mays	23%	100%
B4FIJ0	Zea mays	23%	100%
B5VI70	Saccharomyces cerevisiae (strain AWRI1631)	22%	100%
B6ZJZ9	Glycine max	20%	100%
B8ZHC9	Rattus norvegicus	24%	100%
C9ZKK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZNU5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
C9ZVP0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	99%
C9ZW54	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZYS8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZZ11	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
D0A0Q8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A5E9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A728	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A9Y8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A9Z0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
E9AEE0	Leishmania major	24%	100%
E9AFF7	Leishmania major	89%	100%
E9ALE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AQ09	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AS62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AX97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B2N6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B2N7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
F1R4U0	Danio rerio	24%	100%
F1RFX9	Sus scrofa	27%	100%
F4HT41	Arabidopsis thaliana	24%	100%
F4HW79	Arabidopsis thaliana	26%	100%
F4JU70	Arabidopsis thaliana	23%	100%
G5EE96	Caenorhabditis elegans	25%	100%
K7VYZ9	Zea mays	24%	100%
O04200	Arabidopsis thaliana	22%	100%
O04619	Arabidopsis thaliana	22%	100%
O13660	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O13844	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
O14281	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
O18757	Oryctolagus cuniculus	24%	76%
O22261	Arabidopsis thaliana	29%	100%
O43808	Homo sapiens	28%	100%
O59674	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
O60029	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	100%
O65023	Arabidopsis thaliana	22%	95%
O70579	Mus musculus	27%	100%
O77792	Bos taurus	25%	100%
O94370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
O94502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	85%
O95258	Homo sapiens	24%	100%
O95847	Homo sapiens	25%	100%
O97649	Sus scrofa	26%	100%
P0C582	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	21%	100%
P0CAT2	Danio rerio	24%	100%
P21245	Candida boidinii	21%	86%
P22292	Bos taurus	26%	100%
P23500	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P29518	Zea mays	26%	83%
P32089	Rattus norvegicus	25%	100%
P32332	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P33303	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P34519	Caenorhabditis elegans	22%	100%
P38127	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	96%
P38152	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P39953	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P40464	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P40556	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	97%
P43617	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
P53007	Homo sapiens	25%	100%
P53257	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P55916	Homo sapiens	24%	100%
P56499	Rattus norvegicus	25%	100%
P56500	Rattus norvegicus	27%	100%
P56501	Mus musculus	25%	100%
P70406	Mus musculus	24%	100%
P79110	Bos taurus	27%	100%
P90992	Caenorhabditis elegans	22%	100%
P97700	Rattus norvegicus	25%	100%
Q02978	Homo sapiens	25%	100%
Q03829	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	98%
Q06143	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
Q08CI8	Danio rerio	27%	100%
Q08DK4	Bos taurus	24%	100%
Q08DK7	Bos taurus	23%	100%
Q09834	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q0CEN9	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	26%	100%
Q0CT66	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	23%	100%
Q0UUH1	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	27%	100%
Q0V7M4	Bos taurus	24%	77%
Q10248	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q10442	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q12251	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q19529	Caenorhabditis elegans	24%	68%
Q1E7P0	Coccidioides immitis (strain RS)	24%	100%
Q1ECW7	Danio rerio	26%	100%
Q1LZB3	Bos taurus	24%	100%
Q23125	Caenorhabditis elegans	24%	100%
Q287T7	Danio rerio	26%	100%
Q29RM1	Bos taurus	25%	100%
Q2H608	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	22%	100%
Q2HFL6	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	27%	100%
Q2UCW8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	24%	100%
Q2UU67	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	22%	100%
Q3MHI3	Bos taurus	25%	100%
Q3SZI5	Bos taurus	23%	100%
Q3TZX3	Mus musculus	23%	100%
Q499U1	Rattus norvegicus	27%	100%
Q4Q5H0	Leishmania major	26%	100%
Q4Q5H1	Leishmania major	27%	100%
Q4Q7J8	Leishmania major	24%	100%
Q4QA75	Leishmania major	22%	100%
Q4QDA4	Leishmania major	24%	100%
Q4QF00	Leishmania major	21%	100%
Q4QFH2	Leishmania major	26%	100%
Q4V9P0	Danio rerio	22%	100%
Q4WQC5	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	23%	100%
Q4X022	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	25%	100%
Q54BM3	Dictyostelium discoideum	25%	100%
Q54DU1	Dictyostelium discoideum	23%	100%
Q54EV4	Dictyostelium discoideum	24%	100%
Q54FE6	Dictyostelium discoideum	24%	100%
Q54FU9	Dictyostelium discoideum	29%	100%
Q54MZ4	Dictyostelium discoideum	22%	83%
Q54PY7	Dictyostelium discoideum	22%	100%
Q54QI8	Dictyostelium discoideum	23%	100%
Q54QN2	Dictyostelium discoideum	27%	100%
Q54W11	Dictyostelium discoideum	21%	100%
Q552L9	Dictyostelium discoideum	21%	99%
Q55BF4	Dictyostelium discoideum	22%	100%
Q55DY8	Dictyostelium discoideum	22%	100%
Q55E45	Dictyostelium discoideum	22%	100%
Q55E85	Dictyostelium discoideum	23%	100%
Q55GE2	Dictyostelium discoideum	24%	100%
Q59Q36	Candida albicans (strain SC5314 / ATCC MYA-2876)	24%	100%
Q5AVW1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	100%
Q5B717	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	22%	100%
Q5EAC0	Bos taurus	24%	100%
Q5HZE0	Rattus norvegicus	22%	100%
Q5IS35	Macaca fascicularis	24%	100%
Q5NVC1	Pongo abelii	24%	100%
Q5PQM9	Rattus norvegicus	25%	100%
Q5RD67	Pongo abelii	22%	100%
Q5RD81	Pongo abelii	26%	100%
Q5RFB7	Pongo abelii	24%	100%
Q5SVS4	Homo sapiens	25%	100%
Q5U680	Mus musculus	21%	100%
Q5XGI1	Xenopus tropicalis	22%	100%
Q5XH95	Xenopus tropicalis	23%	71%
Q5XHA0	Xenopus tropicalis	25%	77%
Q5ZKP7	Gallus gallus	25%	100%
Q620A6	Caenorhabditis briggsae	24%	100%
Q628Z2	Caenorhabditis briggsae	24%	68%
Q641C8	Xenopus laevis	23%	100%
Q66H23	Rattus norvegicus	23%	100%
Q66L49	Danio rerio	23%	76%
Q6BPW0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	20%	100%
Q6CQR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	22%	100%
Q6DE75	Xenopus laevis	25%	100%
Q6DG32	Danio rerio	25%	100%
Q6DHS9	Danio rerio	27%	100%
Q6DJ08	Xenopus tropicalis	23%	100%
Q6FR88	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	21%	100%
Q6GLA2	Xenopus tropicalis	22%	100%
Q6GQ22	Xenopus laevis	23%	100%
Q6GQS1	Mus musculus	26%	78%
Q6IS41	Mus musculus	25%	100%
Q6IZB5	Cricetulus griseus	30%	100%
Q6J329	Rattus norvegicus	24%	100%
Q6KCM7	Homo sapiens	24%	77%
Q6NUK1	Homo sapiens	23%	76%
Q6NYZ6	Danio rerio	25%	77%
Q6P036	Danio rerio	26%	100%
Q6PGY3	Danio rerio	27%	100%
Q6Q0C1	Homo sapiens	23%	100%
Q6ZT89	Homo sapiens	27%	100%
Q74Z23	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q76P23	Dictyostelium discoideum	21%	100%
Q76PC3	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q7K566	Drosophila melanogaster	24%	100%
Q7S2H8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	100%
Q7T0U6	Xenopus laevis	24%	77%
Q7T292	Danio rerio	26%	96%
Q7XA87	Arabidopsis thaliana	31%	100%
Q7ZY36	Xenopus laevis	23%	77%
Q7ZYD5	Xenopus laevis	24%	70%
Q84UC7	Arabidopsis thaliana	27%	100%
Q86AV5	Dictyostelium discoideum	22%	100%
Q86I81	Dictyostelium discoideum	22%	100%
Q8BGF9	Mus musculus	23%	100%
Q8BL03	Mus musculus	23%	100%
Q8BMD8	Mus musculus	24%	76%
Q8BMG8	Mus musculus	30%	100%
Q8BVN7	Mus musculus	23%	100%
Q8BW66	Mus musculus	25%	100%
Q8BZ09	Mus musculus	29%	100%
Q8CFJ7	Mus musculus	25%	100%
Q8HXE3	Macaca fascicularis	25%	100%
Q8J2Q9	Gibberella moniliformis (strain M3125 / FGSC 7600)	23%	100%
Q8JZU2	Mus musculus	23%	100%
Q8K3P6	Rattus norvegicus	24%	77%
Q8N413	Homo sapiens	27%	100%
Q8N5S1	Homo sapiens	23%	98%
Q8N8R3	Homo sapiens	23%	100%
Q8R0Z5	Mus musculus	26%	99%
Q8RWA5	Arabidopsis thaliana	30%	100%
Q8RXZ9	Arabidopsis thaliana	22%	100%
Q8TFH2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q91XD8	Mus musculus	24%	100%
Q920G8	Mus musculus	23%	100%
Q922G0	Mus musculus	24%	100%
Q93XM7	Arabidopsis thaliana	26%	100%
Q944H5	Arabidopsis thaliana	25%	88%
Q94AG6	Arabidopsis thaliana	23%	100%
Q95J75	Macaca fascicularis	29%	100%
Q96A46	Homo sapiens	27%	99%
Q96CQ1	Homo sapiens	24%	100%
Q96DW6	Homo sapiens	24%	100%
Q96H78	Homo sapiens	22%	100%
Q96U08	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q99JD3	Rattus norvegicus	28%	100%
Q9BQT8	Homo sapiens	25%	100%
Q9BSK2	Homo sapiens	24%	100%
Q9BV35	Homo sapiens	25%	77%
Q9BXI2	Homo sapiens	22%	100%
Q9CA93	Arabidopsis thaliana	27%	100%
Q9CR58	Mus musculus	25%	100%
Q9CR62	Mus musculus	27%	100%
Q9D6M3	Mus musculus	25%	100%
Q9DAM5	Mus musculus	24%	100%
Q9FI43	Arabidopsis thaliana	24%	74%
Q9FI73	Arabidopsis thaliana	22%	100%
Q9FLS8	Arabidopsis thaliana	26%	76%
Q9H1K4	Homo sapiens	23%	100%
Q9H2D1	Homo sapiens	28%	100%
Q9H936	Homo sapiens	26%	100%
Q9HC21	Homo sapiens	24%	100%
Q9LJX5	Arabidopsis thaliana	24%	100%
Q9LY28	Arabidopsis thaliana	28%	76%
Q9M024	Arabidopsis thaliana	22%	87%
Q9M038	Arabidopsis thaliana	26%	100%
Q9N2I9	Canis lupus familiaris	25%	100%
Q9N2J1	Canis lupus familiaris	24%	100%
Q9NYZ2	Homo sapiens	23%	100%
Q9P6L7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
Q9P6N6	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q9P7V8	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q9SUV1	Arabidopsis thaliana	26%	92%
Q9UTD6	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	98%
Q9UTN1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q9VAY3	Drosophila melanogaster	24%	96%
Q9VBN7	Drosophila melanogaster	22%	100%
Q9VM51	Drosophila melanogaster	23%	100%
Q9VMK1	Drosophila melanogaster	24%	100%
Q9VQ37	Drosophila melanogaster	25%	99%
Q9VWG0	Drosophila melanogaster	27%	94%
Q9WVD5	Mus musculus	22%	100%
Q9XI74	Arabidopsis thaliana	23%	100%
Q9Y619	Homo sapiens	21%	100%
Q9Z2B2	Mus musculus	25%	100%
V5B150	Trypanosoma cruzi	24%	100%
V5BD15	Trypanosoma cruzi	26%	100%
V5BGM6	Trypanosoma cruzi	25%	100%
V5BSW1	Trypanosoma cruzi	25%	100%
V5BTA6	Trypanosoma cruzi	25%	100%
V5BTE8	Trypanosoma cruzi	53%	100%
V5BVW0	Trypanosoma cruzi	24%	100%
V5C243	Trypanosoma cruzi	25%	100%
V5DCQ7	Trypanosoma cruzi	26%	100%
V5DDT9	Trypanosoma cruzi	22%	94%