WGS CADB00000000 data, contig 55

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHL0_LEIMU

TriTrypDb:

LmxM.08.0790a

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E8NHL0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHL0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.562
CLV_NRD_NRD_1	140	142	PF00675	0.552
CLV_NRD_NRD_1	186	188	PF00675	0.531
CLV_NRD_NRD_1	23	25	PF00675	0.583
CLV_PCSK_KEX2_1	113	115	PF00082	0.562
CLV_PCSK_KEX2_1	140	142	PF00082	0.552
CLV_PCSK_KEX2_1	186	188	PF00082	0.581
CLV_PCSK_KEX2_1	23	25	PF00082	0.684
CLV_PCSK_KEX2_1	30	32	PF00082	0.699
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.739
CLV_PCSK_SKI1_1	113	117	PF00082	0.562
CLV_PCSK_SKI1_1	133	137	PF00082	0.418
CLV_PCSK_SKI1_1	31	35	PF00082	0.549
DEG_SPOP_SBC_1	170	174	PF00917	0.539
DOC_MAPK_gen_1	71	80	PF00069	0.490
DOC_MAPK_MEF2A_6	59	68	PF00069	0.628
DOC_USP7_MATH_1	169	173	PF00917	0.538
DOC_WW_Pin1_4	84	89	PF00397	0.507
LIG_14-3-3_CanoR_1	186	190	PF00244	0.528
LIG_14-3-3_CanoR_1	31	39	PF00244	0.605
LIG_14-3-3_CanoR_1	7	12	PF00244	0.750
LIG_14-3-3_CanoR_1	97	107	PF00244	0.567
LIG_BIR_II_1	1	5	PF00653	0.587
LIG_DLG_GKlike_1	108	116	PF00625	0.566
LIG_FHA_1	121	127	PF00498	0.528
LIG_FHA_1	32	38	PF00498	0.639
LIG_FHA_2	171	177	PF00498	0.540
LIG_Integrin_RGD_1	24	26	PF01839	0.584
LIG_PTAP_UEV_1	164	169	PF05743	0.533
LIG_SH3_3	159	165	PF00018	0.529
LIG_SH3_3	52	58	PF00018	0.656
LIG_SUMO_SIM_anti_2	62	68	PF11976	0.541
LIG_SUMO_SIM_par_1	65	70	PF11976	0.493
MOD_CK1_1	124	130	PF00069	0.508
MOD_CK1_1	172	178	PF00069	0.542
MOD_CK2_1	170	176	PF00069	0.538
MOD_CK2_1	90	96	PF00069	0.613
MOD_GlcNHglycan	126	129	PF01048	0.509
MOD_GlcNHglycan	165	168	PF01048	0.531
MOD_GlcNHglycan	31	34	PF01048	0.567
MOD_GSK3_1	120	127	PF00069	0.543
MOD_GSK3_1	181	188	PF00069	0.537
MOD_GSK3_1	29	36	PF00069	0.643
MOD_NEK2_1	1	6	PF00069	0.639
MOD_NEK2_1	185	190	PF00069	0.540
MOD_NEK2_2	181	186	PF00069	0.541
MOD_PKA_2	96	102	PF00069	0.558
MOD_PKB_1	106	114	PF00069	0.576
MOD_Plk_1	44	50	PF00069	0.759
MOD_Plk_4	158	164	PF00069	0.529
MOD_ProDKin_1	84	90	PF00069	0.512
TRG_DiLeu_BaEn_1	62	67	PF01217	0.550
TRG_DiLeu_BaEn_1	76	81	PF01217	0.430
TRG_DiLeu_LyEn_5	76	81	PF01217	0.485
TRG_ER_diArg_1	112	114	PF00400	0.574
TRG_ER_diArg_1	148	151	PF00400	0.540
TRG_ER_diArg_1	185	187	PF00400	0.541
TRG_ER_diArg_1	22	24	PF00400	0.591
TRG_ER_diArg_1	77	80	PF00400	0.483
TRG_Pf-PMV_PEXEL_1	114	118	PF00026	0.547
TRG_Pf-PMV_PEXEL_1	79	83	PF00026	0.492

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HB03	Leishmania braziliensis	40%	69%
E8NHH0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%