LeishMANIAdb
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WGS CADB00000000 data, contig 51

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
WGS CADB00000000 data, contig 51
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania mexicana
UniProt:
E8NHK4_LEIMU
TriTrypDb:
Length:
752

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E8NHK4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHK4

Putative motif mimicry

Leishmania From To Domain/Motif Score
DOC_WW_Pin1_4 102 107 PF00397 0.661
DOC_WW_Pin1_4 125 130 PF00397 0.852
DOC_WW_Pin1_4 137 142 PF00397 0.661
DOC_WW_Pin1_4 160 165 PF00397 0.862
DOC_WW_Pin1_4 172 177 PF00397 0.658
DOC_WW_Pin1_4 195 200 PF00397 0.858
DOC_WW_Pin1_4 20 25 PF00397 0.860
DOC_WW_Pin1_4 207 212 PF00397 0.646
DOC_WW_Pin1_4 230 235 PF00397 0.845
DOC_WW_Pin1_4 242 247 PF00397 0.639
DOC_WW_Pin1_4 265 270 PF00397 0.835
DOC_WW_Pin1_4 277 282 PF00397 0.643
DOC_WW_Pin1_4 300 305 PF00397 0.829
DOC_WW_Pin1_4 312 317 PF00397 0.641
DOC_WW_Pin1_4 32 37 PF00397 0.673
DOC_WW_Pin1_4 335 340 PF00397 0.823
DOC_WW_Pin1_4 347 352 PF00397 0.638
DOC_WW_Pin1_4 370 375 PF00397 0.822
DOC_WW_Pin1_4 382 387 PF00397 0.641
DOC_WW_Pin1_4 405 410 PF00397 0.828
DOC_WW_Pin1_4 420 425 PF00397 0.573
DOC_WW_Pin1_4 440 445 PF00397 0.482
DOC_WW_Pin1_4 452 457 PF00397 0.646
DOC_WW_Pin1_4 475 480 PF00397 0.834
DOC_WW_Pin1_4 487 492 PF00397 0.651
DOC_WW_Pin1_4 510 515 PF00397 0.831
DOC_WW_Pin1_4 522 527 PF00397 0.653
DOC_WW_Pin1_4 545 550 PF00397 0.832
DOC_WW_Pin1_4 55 60 PF00397 0.869
DOC_WW_Pin1_4 557 562 PF00397 0.652
DOC_WW_Pin1_4 580 585 PF00397 0.837
DOC_WW_Pin1_4 592 597 PF00397 0.650
DOC_WW_Pin1_4 615 620 PF00397 0.840
DOC_WW_Pin1_4 627 632 PF00397 0.652
DOC_WW_Pin1_4 650 655 PF00397 0.842
DOC_WW_Pin1_4 662 667 PF00397 0.663
DOC_WW_Pin1_4 67 72 PF00397 0.661
DOC_WW_Pin1_4 685 690 PF00397 0.858
DOC_WW_Pin1_4 697 702 PF00397 0.667
DOC_WW_Pin1_4 720 725 PF00397 0.873
DOC_WW_Pin1_4 732 737 PF00397 0.667
DOC_WW_Pin1_4 90 95 PF00397 0.862
LIG_GSK3_LRP6_1 125 130 PF00069 0.852
LIG_GSK3_LRP6_1 160 165 PF00069 0.862
LIG_GSK3_LRP6_1 195 200 PF00069 0.858
LIG_GSK3_LRP6_1 20 25 PF00069 0.860
LIG_GSK3_LRP6_1 230 235 PF00069 0.845
LIG_GSK3_LRP6_1 265 270 PF00069 0.835
LIG_GSK3_LRP6_1 300 305 PF00069 0.829
LIG_GSK3_LRP6_1 335 340 PF00069 0.823
LIG_GSK3_LRP6_1 370 375 PF00069 0.822
LIG_GSK3_LRP6_1 405 410 PF00069 0.828
LIG_GSK3_LRP6_1 440 445 PF00069 0.832
LIG_GSK3_LRP6_1 475 480 PF00069 0.834
LIG_GSK3_LRP6_1 510 515 PF00069 0.831
LIG_GSK3_LRP6_1 545 550 PF00069 0.832
LIG_GSK3_LRP6_1 55 60 PF00069 0.869
LIG_GSK3_LRP6_1 580 585 PF00069 0.837
LIG_GSK3_LRP6_1 615 620 PF00069 0.840
LIG_GSK3_LRP6_1 650 655 PF00069 0.842
LIG_GSK3_LRP6_1 685 690 PF00069 0.858
LIG_GSK3_LRP6_1 720 725 PF00069 0.873
LIG_GSK3_LRP6_1 90 95 PF00069 0.862
LIG_SH3_1 123 129 PF00018 0.856
LIG_SH3_1 158 164 PF00018 0.860
LIG_SH3_1 298 304 PF00018 0.828
LIG_SH3_1 368 374 PF00018 0.823
LIG_SH3_1 438 444 PF00018 0.832
LIG_SH3_1 578 584 PF00018 0.840
LIG_SH3_3 103 109 PF00018 0.602
LIG_SH3_3 123 129 PF00018 0.506
LIG_SH3_3 138 144 PF00018 0.605
LIG_SH3_3 158 164 PF00018 0.510
LIG_SH3_3 173 179 PF00018 0.600
LIG_SH3_3 18 24 PF00018 0.866
LIG_SH3_3 193 199 PF00018 0.504
LIG_SH3_3 208 214 PF00018 0.586
LIG_SH3_3 228 234 PF00018 0.489
LIG_SH3_3 243 249 PF00018 0.581
LIG_SH3_3 263 269 PF00018 0.482
LIG_SH3_3 278 284 PF00018 0.586
LIG_SH3_3 298 304 PF00018 0.478
LIG_SH3_3 313 319 PF00018 0.584
LIG_SH3_3 33 39 PF00018 0.617
LIG_SH3_3 333 339 PF00018 0.473
LIG_SH3_3 348 354 PF00018 0.582
LIG_SH3_3 368 374 PF00018 0.473
LIG_SH3_3 383 389 PF00018 0.584
LIG_SH3_3 403 409 PF00018 0.476
LIG_SH3_3 438 444 PF00018 0.832
LIG_SH3_3 453 459 PF00018 0.587
LIG_SH3_3 473 479 PF00018 0.484
LIG_SH3_3 488 494 PF00018 0.588
LIG_SH3_3 508 514 PF00018 0.480
LIG_SH3_3 523 529 PF00018 0.595
LIG_SH3_3 53 59 PF00018 0.517
LIG_SH3_3 543 549 PF00018 0.483
LIG_SH3_3 558 564 PF00018 0.599
LIG_SH3_3 578 584 PF00018 0.490
LIG_SH3_3 593 599 PF00018 0.593
LIG_SH3_3 613 619 PF00018 0.495
LIG_SH3_3 628 634 PF00018 0.599
LIG_SH3_3 648 654 PF00018 0.497
LIG_SH3_3 663 669 PF00018 0.611
LIG_SH3_3 68 74 PF00018 0.603
LIG_SH3_3 683 689 PF00018 0.511
LIG_SH3_3 698 704 PF00018 0.614
LIG_SH3_3 718 724 PF00018 0.524
LIG_SH3_3 733 739 PF00018 0.609
LIG_SH3_3 88 94 PF00018 0.513
LIG_SH3_CIN85_PxpxPR_1 127 132 PF14604 0.853
LIG_SH3_CIN85_PxpxPR_1 162 167 PF14604 0.871
LIG_SH3_CIN85_PxpxPR_1 197 202 PF14604 0.866
LIG_SH3_CIN85_PxpxPR_1 22 27 PF14604 0.863
LIG_SH3_CIN85_PxpxPR_1 232 237 PF14604 0.857
LIG_SH3_CIN85_PxpxPR_1 267 272 PF14604 0.849
LIG_SH3_CIN85_PxpxPR_1 302 307 PF14604 0.842
LIG_SH3_CIN85_PxpxPR_1 337 342 PF14604 0.837
LIG_SH3_CIN85_PxpxPR_1 372 377 PF14604 0.841
LIG_SH3_CIN85_PxpxPR_1 407 412 PF14604 0.849
LIG_SH3_CIN85_PxpxPR_1 442 447 PF14604 0.854
LIG_SH3_CIN85_PxpxPR_1 477 482 PF14604 0.853
LIG_SH3_CIN85_PxpxPR_1 512 517 PF14604 0.846
LIG_SH3_CIN85_PxpxPR_1 547 552 PF14604 0.846
LIG_SH3_CIN85_PxpxPR_1 57 62 PF14604 0.875
LIG_SH3_CIN85_PxpxPR_1 582 587 PF14604 0.849
LIG_SH3_CIN85_PxpxPR_1 617 622 PF14604 0.850
LIG_SH3_CIN85_PxpxPR_1 652 657 PF14604 0.852
LIG_SH3_CIN85_PxpxPR_1 687 692 PF14604 0.864
LIG_SH3_CIN85_PxpxPR_1 722 727 PF14604 0.880
LIG_SH3_CIN85_PxpxPR_1 92 97 PF14604 0.866
MOD_CDK_SPK_2 102 107 PF00069 0.697
MOD_CDK_SPK_2 127 132 PF00069 0.853
MOD_CDK_SPK_2 137 142 PF00069 0.696
MOD_CDK_SPK_2 162 167 PF00069 0.871
MOD_CDK_SPK_2 172 177 PF00069 0.693
MOD_CDK_SPK_2 197 202 PF00069 0.866
MOD_CDK_SPK_2 207 212 PF00069 0.681
MOD_CDK_SPK_2 22 27 PF00069 0.863
MOD_CDK_SPK_2 232 237 PF00069 0.857
MOD_CDK_SPK_2 242 247 PF00069 0.674
MOD_CDK_SPK_2 267 272 PF00069 0.849
MOD_CDK_SPK_2 277 282 PF00069 0.678
MOD_CDK_SPK_2 302 307 PF00069 0.842
MOD_CDK_SPK_2 312 317 PF00069 0.676
MOD_CDK_SPK_2 32 37 PF00069 0.708
MOD_CDK_SPK_2 337 342 PF00069 0.837
MOD_CDK_SPK_2 347 352 PF00069 0.673
MOD_CDK_SPK_2 372 377 PF00069 0.841
MOD_CDK_SPK_2 382 387 PF00069 0.676
MOD_CDK_SPK_2 407 412 PF00069 0.849
MOD_CDK_SPK_2 442 447 PF00069 0.854
MOD_CDK_SPK_2 452 457 PF00069 0.681
MOD_CDK_SPK_2 477 482 PF00069 0.853
MOD_CDK_SPK_2 487 492 PF00069 0.686
MOD_CDK_SPK_2 512 517 PF00069 0.846
MOD_CDK_SPK_2 522 527 PF00069 0.688
MOD_CDK_SPK_2 547 552 PF00069 0.846
MOD_CDK_SPK_2 557 562 PF00069 0.687
MOD_CDK_SPK_2 57 62 PF00069 0.875
MOD_CDK_SPK_2 582 587 PF00069 0.849
MOD_CDK_SPK_2 592 597 PF00069 0.685
MOD_CDK_SPK_2 617 622 PF00069 0.850
MOD_CDK_SPK_2 627 632 PF00069 0.687
MOD_CDK_SPK_2 652 657 PF00069 0.852
MOD_CDK_SPK_2 662 667 PF00069 0.698
MOD_CDK_SPK_2 67 72 PF00069 0.696
MOD_CDK_SPK_2 687 692 PF00069 0.864
MOD_CDK_SPK_2 697 702 PF00069 0.702
MOD_CDK_SPK_2 722 727 PF00069 0.880
MOD_CDK_SPK_2 732 737 PF00069 0.702
MOD_CDK_SPK_2 92 97 PF00069 0.866
MOD_CDK_SPxxK_3 125 132 PF00069 0.852
MOD_CDK_SPxxK_3 160 167 PF00069 0.867
MOD_CDK_SPxxK_3 195 202 PF00069 0.862
MOD_CDK_SPxxK_3 20 27 PF00069 0.863
MOD_CDK_SPxxK_3 230 237 PF00069 0.851
MOD_CDK_SPxxK_3 265 272 PF00069 0.842
MOD_CDK_SPxxK_3 300 307 PF00069 0.835
MOD_CDK_SPxxK_3 335 342 PF00069 0.830
MOD_CDK_SPxxK_3 370 377 PF00069 0.832
MOD_CDK_SPxxK_3 405 412 PF00069 0.839
MOD_CDK_SPxxK_3 440 447 PF00069 0.844
MOD_CDK_SPxxK_3 475 482 PF00069 0.845
MOD_CDK_SPxxK_3 510 517 PF00069 0.839
MOD_CDK_SPxxK_3 545 552 PF00069 0.839
MOD_CDK_SPxxK_3 55 62 PF00069 0.871
MOD_CDK_SPxxK_3 580 587 PF00069 0.843
MOD_CDK_SPxxK_3 615 622 PF00069 0.845
MOD_CDK_SPxxK_3 650 657 PF00069 0.848
MOD_CDK_SPxxK_3 685 692 PF00069 0.862
MOD_CDK_SPxxK_3 720 727 PF00069 0.876
MOD_CDK_SPxxK_3 90 97 PF00069 0.863
MOD_CK1_1 105 111 PF00069 0.849
MOD_CK1_1 140 146 PF00069 0.865
MOD_CK1_1 175 181 PF00069 0.858
MOD_CK1_1 210 216 PF00069 0.843
MOD_CK1_1 245 251 PF00069 0.837
MOD_CK1_1 280 286 PF00069 0.841
MOD_CK1_1 315 321 PF00069 0.840
MOD_CK1_1 35 41 PF00069 0.873
MOD_CK1_1 350 356 PF00069 0.838
MOD_CK1_1 385 391 PF00069 0.839
MOD_CK1_1 420 426 PF00069 0.836
MOD_CK1_1 455 461 PF00069 0.844
MOD_CK1_1 490 496 PF00069 0.845
MOD_CK1_1 525 531 PF00069 0.851
MOD_CK1_1 560 566 PF00069 0.859
MOD_CK1_1 595 601 PF00069 0.857
MOD_CK1_1 630 636 PF00069 0.863
MOD_CK1_1 665 671 PF00069 0.878
MOD_CK1_1 70 76 PF00069 0.862
MOD_CK1_1 700 706 PF00069 0.880
MOD_CK1_1 735 741 PF00069 0.866
MOD_GlcNHglycan 134 137 PF01048 0.869
MOD_GlcNHglycan 169 172 PF01048 0.871
MOD_GlcNHglycan 204 207 PF01048 0.861
MOD_GlcNHglycan 239 242 PF01048 0.849
MOD_GlcNHglycan 274 277 PF01048 0.846
MOD_GlcNHglycan 29 32 PF01048 0.895
MOD_GlcNHglycan 309 312 PF01048 0.854
MOD_GlcNHglycan 344 347 PF01048 0.847
MOD_GlcNHglycan 379 382 PF01048 0.854
MOD_GlcNHglycan 414 417 PF01048 0.865
MOD_GlcNHglycan 449 452 PF01048 0.873
MOD_GlcNHglycan 484 487 PF01048 0.876
MOD_GlcNHglycan 519 522 PF01048 0.868
MOD_GlcNHglycan 554 557 PF01048 0.865
MOD_GlcNHglycan 589 592 PF01048 0.869
MOD_GlcNHglycan 624 627 PF01048 0.867
MOD_GlcNHglycan 64 67 PF01048 0.875
MOD_GlcNHglycan 659 662 PF01048 0.866
MOD_GlcNHglycan 694 697 PF01048 0.869
MOD_GlcNHglycan 729 732 PF01048 0.881
MOD_GlcNHglycan 99 102 PF01048 0.861
MOD_PIKK_1 14 20 PF00454 0.876
MOD_PIKK_1 189 195 PF00454 0.837
MOD_PIKK_1 224 230 PF00454 0.822
MOD_PIKK_1 259 265 PF00454 0.815
MOD_PIKK_1 329 335 PF00454 0.806
MOD_PIKK_1 399 405 PF00454 0.811
MOD_PIKK_1 469 475 PF00454 0.823
MOD_PIKK_1 49 55 PF00454 0.868
MOD_PIKK_1 504 510 PF00454 0.820
MOD_PIKK_1 539 545 PF00454 0.824
MOD_PIKK_1 609 615 PF00454 0.846
MOD_PIKK_1 644 650 PF00454 0.847
MOD_PIKK_1 679 685 PF00454 0.857
MOD_PIKK_1 714 720 PF00454 0.874
MOD_PIKK_1 84 90 PF00454 0.858
MOD_ProDKin_1 102 108 PF00069 0.658
MOD_ProDKin_1 125 131 PF00069 0.850
MOD_ProDKin_1 137 143 PF00069 0.660
MOD_ProDKin_1 160 166 PF00069 0.865
MOD_ProDKin_1 172 178 PF00069 0.659
MOD_ProDKin_1 195 201 PF00069 0.861
MOD_ProDKin_1 20 26 PF00069 0.859
MOD_ProDKin_1 207 213 PF00069 0.647
MOD_ProDKin_1 230 236 PF00069 0.851
MOD_ProDKin_1 242 248 PF00069 0.640
MOD_ProDKin_1 265 271 PF00069 0.842
MOD_ProDKin_1 277 283 PF00069 0.642
MOD_ProDKin_1 300 306 PF00069 0.835
MOD_ProDKin_1 312 318 PF00069 0.640
MOD_ProDKin_1 32 38 PF00069 0.671
MOD_ProDKin_1 335 341 PF00069 0.828
MOD_ProDKin_1 347 353 PF00069 0.637
MOD_ProDKin_1 370 376 PF00069 0.829
MOD_ProDKin_1 382 388 PF00069 0.640
MOD_ProDKin_1 405 411 PF00069 0.836
MOD_ProDKin_1 420 426 PF00069 0.573
MOD_ProDKin_1 440 446 PF00069 0.491
MOD_ProDKin_1 452 458 PF00069 0.646
MOD_ProDKin_1 475 481 PF00069 0.843
MOD_ProDKin_1 487 493 PF00069 0.650
MOD_ProDKin_1 510 516 PF00069 0.838
MOD_ProDKin_1 522 528 PF00069 0.651
MOD_ProDKin_1 545 551 PF00069 0.838
MOD_ProDKin_1 55 61 PF00069 0.869
MOD_ProDKin_1 557 563 PF00069 0.651
MOD_ProDKin_1 580 586 PF00069 0.842
MOD_ProDKin_1 592 598 PF00069 0.650
MOD_ProDKin_1 615 621 PF00069 0.844
MOD_ProDKin_1 627 633 PF00069 0.653
MOD_ProDKin_1 650 656 PF00069 0.847
MOD_ProDKin_1 662 668 PF00069 0.663
MOD_ProDKin_1 67 73 PF00069 0.658
MOD_ProDKin_1 685 691 PF00069 0.862
MOD_ProDKin_1 697 703 PF00069 0.668
MOD_ProDKin_1 720 726 PF00069 0.876
MOD_ProDKin_1 732 738 PF00069 0.666
MOD_ProDKin_1 90 96 PF00069 0.863
TRG_ER_diArg_1 131 134 PF00400 0.859
TRG_ER_diArg_1 166 169 PF00400 0.883
TRG_ER_diArg_1 201 204 PF00400 0.874
TRG_ER_diArg_1 236 239 PF00400 0.851
TRG_ER_diArg_1 26 29 PF00400 0.883
TRG_ER_diArg_1 271 274 PF00400 0.862
TRG_ER_diArg_1 306 309 PF00400 0.859
TRG_ER_diArg_1 341 344 PF00400 0.856
TRG_ER_diArg_1 376 379 PF00400 0.866
TRG_ER_diArg_1 411 414 PF00400 0.875
TRG_ER_diArg_1 446 449 PF00400 0.879
TRG_ER_diArg_1 481 484 PF00400 0.876
TRG_ER_diArg_1 516 519 PF00400 0.864
TRG_ER_diArg_1 551 554 PF00400 0.863
TRG_ER_diArg_1 586 589 PF00400 0.866
TRG_ER_diArg_1 61 64 PF00400 0.877
TRG_ER_diArg_1 621 624 PF00400 0.864
TRG_ER_diArg_1 656 659 PF00400 0.865
TRG_ER_diArg_1 691 694 PF00400 0.873
TRG_ER_diArg_1 726 729 PF00400 0.885
TRG_ER_diArg_1 96 99 PF00400 0.863

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS