WGS CADB00000000 data, contig 47

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid kinetochore protein 19, putative

Species:

Leishmania mexicana

UniProt:

E8NHK0_LEIMU

TriTrypDb:

LmxM.09.0410

Length:

416

Annotations

LeishMANIAdb annotations

A large and apprently artificial collection of diverse kinetoplastid protein kinases. A subfamily has 2TM regions, but the majority is cytoplasmic.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 17
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0051286	cell tip	3	2
GO:0060187	cell pole	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E8NHK0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHK0

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	18
GO:0006793	phosphorus metabolic process	3	18
GO:0006796	phosphate-containing compound metabolic process	4	18
GO:0006807	nitrogen compound metabolic process	2	18
GO:0008152	metabolic process	1	18
GO:0009987	cellular process	1	18
GO:0016310	phosphorylation	5	18
GO:0019538	protein metabolic process	3	18
GO:0036211	protein modification process	4	18
GO:0043170	macromolecule metabolic process	3	18
GO:0043412	macromolecule modification	4	18
GO:0044237	cellular metabolic process	2	18
GO:0044238	primary metabolic process	2	18
GO:0071704	organic substance metabolic process	2	18
GO:1901564	organonitrogen compound metabolic process	3	18
GO:0000278	mitotic cell cycle	3	1
GO:0007049	cell cycle	2	1
GO:0008283	cell population proliferation	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	18
GO:0003824	catalytic activity	1	18
GO:0004672	protein kinase activity	3	18
GO:0004674	protein serine/threonine kinase activity	4	16
GO:0005488	binding	1	18
GO:0005524	ATP binding	5	18
GO:0016301	kinase activity	4	18
GO:0016740	transferase activity	2	18
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	18
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	18
GO:0017076	purine nucleotide binding	4	18
GO:0030554	adenyl nucleotide binding	5	18
GO:0032553	ribonucleotide binding	3	18
GO:0032555	purine ribonucleotide binding	4	18
GO:0032559	adenyl ribonucleotide binding	5	18
GO:0035639	purine ribonucleoside triphosphate binding	4	18
GO:0036094	small molecule binding	2	18
GO:0043167	ion binding	2	18
GO:0043168	anion binding	3	18
GO:0097159	organic cyclic compound binding	2	18
GO:0097367	carbohydrate derivative binding	2	18
GO:0140096	catalytic activity, acting on a protein	2	18
GO:1901265	nucleoside phosphate binding	3	18
GO:1901363	heterocyclic compound binding	2	18

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	402	406	PF00656	0.570
CLV_NRD_NRD_1	18	20	PF00675	0.684
CLV_NRD_NRD_1	99	101	PF00675	0.321
CLV_PCSK_FUR_1	375	379	PF00082	0.334
CLV_PCSK_KEX2_1	101	103	PF00082	0.321
CLV_PCSK_KEX2_1	18	20	PF00082	0.656
CLV_PCSK_KEX2_1	23	25	PF00082	0.646
CLV_PCSK_KEX2_1	377	379	PF00082	0.334
CLV_PCSK_PC1ET2_1	101	103	PF00082	0.321
CLV_PCSK_PC1ET2_1	23	25	PF00082	0.653
CLV_PCSK_PC1ET2_1	377	379	PF00082	0.350
CLV_PCSK_PC7_1	19	25	PF00082	0.680
CLV_PCSK_SKI1_1	119	123	PF00082	0.342
CLV_PCSK_SKI1_1	382	386	PF00082	0.368
CLV_PCSK_SKI1_1	407	411	PF00082	0.585
CLV_PCSK_SKI1_1	49	53	PF00082	0.572
DEG_APCC_DBOX_1	138	146	PF00400	0.315
DOC_CYCLIN_RxL_1	78	88	PF00134	0.334
DOC_MAPK_gen_1	100	110	PF00069	0.321
DOC_MAPK_gen_1	116	125	PF00069	0.321
DOC_MAPK_gen_1	258	267	PF00069	0.321
DOC_MAPK_HePTP_8	255	267	PF00069	0.321
DOC_MAPK_MEF2A_6	119	127	PF00069	0.350
DOC_MAPK_MEF2A_6	258	267	PF00069	0.321
DOC_PP2B_LxvP_1	410	413	PF13499	0.596
DOC_PP2B_LxvP_1	43	46	PF13499	0.426
DOC_SPAK_OSR1_1	79	83	PF12202	0.321
DOC_USP7_MATH_1	253	257	PF00917	0.334
DOC_USP7_MATH_1	395	399	PF00917	0.416
DOC_WW_Pin1_4	259	264	PF00397	0.318
LIG_14-3-3_CanoR_1	337	342	PF00244	0.361
LIG_14-3-3_CanoR_1	350	355	PF00244	0.367
LIG_14-3-3_CanoR_1	382	388	PF00244	0.323
LIG_BIR_II_1	1	5	PF00653	0.488
LIG_BIR_III_3	1	5	PF00653	0.472
LIG_deltaCOP1_diTrp_1	169	177	PF00928	0.350
LIG_EH1_1	79	87	PF00400	0.321
LIG_FHA_1	250	256	PF00498	0.334
LIG_FHA_1	287	293	PF00498	0.309
LIG_FHA_1	50	56	PF00498	0.528
LIG_FHA_2	217	223	PF00498	0.353
LIG_FHA_2	351	357	PF00498	0.400
LIG_LIR_Apic_2	257	263	PF02991	0.309
LIG_LIR_Apic_2	52	56	PF02991	0.511
LIG_LIR_Gen_1	104	111	PF02991	0.321
LIG_LIR_Nem_3	104	108	PF02991	0.321
LIG_LIR_Nem_3	365	371	PF02991	0.353
LIG_LIR_Nem_3	62	68	PF02991	0.408
LIG_LIR_Nem_3	77	83	PF02991	0.397
LIG_LIR_Nem_3	88	94	PF02991	0.321
LIG_MYND_1	408	412	PF01753	0.386
LIG_SH2_CRK	105	109	PF00017	0.321
LIG_SH2_CRK	368	372	PF00017	0.353
LIG_SH2_CRK	53	57	PF00017	0.529
LIG_SH2_NCK_1	330	334	PF00017	0.334
LIG_SH2_PTP2	66	69	PF00017	0.418
LIG_SH2_STAP1	117	121	PF00017	0.321
LIG_SH2_STAP1	273	277	PF00017	0.334
LIG_SH2_STAT3	373	376	PF00017	0.350
LIG_SH2_STAT5	105	108	PF00017	0.321
LIG_SH2_STAT5	117	120	PF00017	0.321
LIG_SH2_STAT5	148	151	PF00017	0.309
LIG_SH2_STAT5	195	198	PF00017	0.324
LIG_SH2_STAT5	288	291	PF00017	0.388
LIG_SH2_STAT5	389	392	PF00017	0.391
LIG_SH2_STAT5	53	56	PF00017	0.493
LIG_SH2_STAT5	66	69	PF00017	0.413
LIG_SH3_1	227	233	PF00018	0.334
LIG_SH3_2	230	235	PF14604	0.334
LIG_SH3_3	227	233	PF00018	0.312
LIG_SH3_3	398	404	PF00018	0.428
LIG_TYR_ITIM	366	371	PF00017	0.353
LIG_UBA3_1	167	173	PF00899	0.309
LIG_UBA3_1	283	291	PF00899	0.334
MOD_CK1_1	217	223	PF00069	0.439
MOD_CK1_1	29	35	PF00069	0.694
MOD_CK2_1	7	13	PF00069	0.645
MOD_Cter_Amidation	16	19	PF01082	0.764
MOD_GlcNHglycan	152	155	PF01048	0.444
MOD_GlcNHglycan	19	22	PF01048	0.661
MOD_GlcNHglycan	331	334	PF01048	0.355
MOD_GSK3_1	13	20	PF00069	0.692
MOD_GSK3_1	213	220	PF00069	0.437
MOD_GSK3_1	249	256	PF00069	0.311
MOD_GSK3_1	272	279	PF00069	0.309
MOD_GSK3_1	395	402	PF00069	0.452
MOD_N-GLC_1	150	155	PF02516	0.329
MOD_NEK2_1	306	311	PF00069	0.309
MOD_NEK2_1	329	334	PF00069	0.349
MOD_PIKK_1	395	401	PF00454	0.294
MOD_PIKK_1	74	80	PF00454	0.407
MOD_PKA_1	49	55	PF00069	0.553
MOD_PKA_2	17	23	PF00069	0.682
MOD_PKA_2	247	253	PF00069	0.334
MOD_Plk_1	217	223	PF00069	0.422
MOD_Plk_1	26	32	PF00069	0.791
MOD_Plk_1	306	312	PF00069	0.309
MOD_Plk_4	81	87	PF00069	0.321
MOD_ProDKin_1	259	265	PF00069	0.318
MOD_SUMO_for_1	121	124	PF00179	0.350
MOD_SUMO_for_1	207	210	PF00179	0.309
TRG_DiLeu_BaEn_1	301	306	PF01217	0.309
TRG_DiLeu_BaEn_1	324	329	PF01217	0.444
TRG_DiLeu_BaEn_4	324	330	PF01217	0.350
TRG_DiLeu_LyEn_5	324	329	PF01217	0.444
TRG_ENDOCYTIC_2	105	108	PF00928	0.321
TRG_ENDOCYTIC_2	368	371	PF00928	0.353
TRG_ENDOCYTIC_2	66	69	PF00928	0.407
TRG_ER_diArg_1	235	238	PF00400	0.334
TRG_NLS_MonoCore_2	46	51	PF00514	0.620
TRG_NLS_MonoExtN_4	44	51	PF00514	0.581
TRG_Pf-PMV_PEXEL_1	180	184	PF00026	0.309
TRG_Pf-PMV_PEXEL_1	227	232	PF00026	0.413

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2E2	Leptomonas seymouri	22%	100%
A0A0N0P2X9	Leptomonas seymouri	26%	100%
A0A0N0P3Z9	Leptomonas seymouri	22%	100%
A0A0N0P7D2	Leptomonas seymouri	25%	100%
A0A0N1I0C1	Leptomonas seymouri	24%	94%
A0A0N1I2H3	Leptomonas seymouri	23%	100%
A0A0N1I3G0	Leptomonas seymouri	22%	100%
A0A0N1I9B7	Leptomonas seymouri	27%	100%
A0A0N1IHY4	Leptomonas seymouri	25%	100%
A0A0N1IIU9	Leptomonas seymouri	22%	100%
A0A0N1IJ52	Leptomonas seymouri	27%	83%
A0A0N1IL28	Leptomonas seymouri	24%	100%
A0A0N1P9U2	Leptomonas seymouri	93%	100%
A0A0N1PC32	Leptomonas seymouri	25%	100%
A0A0S4IIU2	Bodo saltans	26%	89%
A0A0S4IKY7	Bodo saltans	24%	100%
A0A0S4IUF2	Bodo saltans	27%	76%
A0A0S4IV16	Bodo saltans	24%	100%
A0A0S4IVF2	Bodo saltans	61%	90%
A0A0S4IYY9	Bodo saltans	59%	89%
A0A0S4J2K6	Bodo saltans	27%	92%
A0A0S4J343	Bodo saltans	24%	74%
A0A0S4J6A5	Bodo saltans	26%	93%
A0A0S4JCK3	Bodo saltans	24%	100%
A0A0S4JFM9	Bodo saltans	22%	100%
A0A0S4JGZ1	Bodo saltans	25%	74%
A0A0S4JIA9	Bodo saltans	24%	100%
A0A0S4JKY3	Bodo saltans	30%	85%
A0A0S4JQ66	Bodo saltans	23%	100%
A0A0S4JUY0	Bodo saltans	30%	70%
A0A0S4JVD7	Bodo saltans	23%	95%
A0A0S4JXW9	Bodo saltans	25%	100%
A0A0S4KHS0	Bodo saltans	28%	100%
A0A1X0NHA6	Trypanosomatidae	23%	79%
A0A1X0NLN7	Trypanosomatidae	25%	100%
A0A1X0NM44	Trypanosomatidae	26%	100%
A0A1X0NMR5	Trypanosomatidae	80%	84%
A0A1X0NMS0	Trypanosomatidae	79%	87%
A0A1X0NQT9	Trypanosomatidae	23%	100%
A0A1X0NTP1	Trypanosomatidae	22%	71%
A0A1X0NWR7	Trypanosomatidae	25%	81%
A0A1X0NYK8	Trypanosomatidae	24%	100%
A0A1X0P020	Trypanosomatidae	26%	100%
A0A1X0P1E8	Trypanosomatidae	24%	100%
A0A1X0P1G1	Trypanosomatidae	27%	74%
A0A1X0P2I7	Trypanosomatidae	22%	99%
A0A1X0P3B9	Trypanosomatidae	24%	100%
A0A1X0P3K5	Trypanosomatidae	28%	90%
A0A1X0P692	Trypanosomatidae	25%	100%
A0A1X0P6E7	Trypanosomatidae	26%	100%
A0A1X0P6U6	Trypanosomatidae	28%	100%
A0A1X0P859	Trypanosomatidae	24%	87%
A0A1X0P8A0	Trypanosomatidae	24%	100%
A0A1X0P8R6	Trypanosomatidae	23%	100%
A0A1X0P919	Trypanosomatidae	24%	100%
A0A3Q8IB74	Leishmania donovani	25%	100%
A0A3Q8IEH3	Leishmania donovani	23%	100%
A0A3Q8II44	Leishmania donovani	24%	100%
A0A3Q8ITZ9	Leishmania donovani	22%	100%
A0A3Q8IVR8	Leishmania donovani	26%	91%
A0A3R7K5U6	Trypanosoma rangeli	26%	71%
A0A3R7K7W6	Trypanosoma rangeli	22%	100%
A0A3R7KDC2	Trypanosoma rangeli	24%	100%
A0A3R7KRL6	Trypanosoma rangeli	27%	91%
A0A3R7LCG7	Trypanosoma rangeli	27%	72%
A0A3R7MKJ1	Trypanosoma rangeli	22%	77%
A0A3R7MSS9	Trypanosoma rangeli	23%	100%
A0A3R7MWP2	Trypanosoma rangeli	27%	100%
A0A3R7NBN7	Trypanosoma rangeli	25%	95%
A0A3S5H6C8	Leishmania donovani	98%	88%
A0A3S5H725	Leishmania donovani	23%	100%
A0A3S5H7N7	Leishmania donovani	21%	100%
A0A3S7WNZ6	Leishmania donovani	22%	100%
A0A3S7WP41	Leishmania donovani	25%	100%
A0A3S7WQK7	Leishmania donovani	91%	89%
A0A3S7WR45	Leishmania donovani	23%	100%
A0A3S7WUE7	Leishmania donovani	23%	75%
A0A3S7X2Z6	Leishmania donovani	24%	100%
A0A3S7X9D1	Leishmania donovani	28%	72%
A0A3S7XA45	Leishmania donovani	26%	100%
A0A422N0M4	Trypanosoma rangeli	25%	100%
A0A422N7C9	Trypanosoma rangeli	86%	66%
A0A422N878	Trypanosoma rangeli	26%	80%
A0A422N9H2	Trypanosoma rangeli	25%	100%
A0A422NCX4	Trypanosoma rangeli	26%	100%
A0A422NDD2	Trypanosoma rangeli	26%	100%
A0A422NL22	Trypanosoma rangeli	23%	69%
A0A422P1R5	Trypanosoma rangeli	25%	100%
A0A422P292	Trypanosoma rangeli	24%	100%
A0A422P2B2	Trypanosoma rangeli	24%	91%
A0A5K1K8H0	Plasmodium falciparum (isolate 3D7)	26%	73%
A1CAF0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	26%	100%
A1CPG7	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	24%	100%
A1D2C9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	24%	100%
A1DES4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	25%	100%
A1IVT7	Botryotinia fuckeliana (strain B05.10)	24%	100%
A2QN07	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	100%
A2QRF6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	100%
A2XFC8	Oryza sativa subsp. indica	23%	100%
A3EZ55	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	24%	100%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	25%	100%
A4H436	Leishmania braziliensis	23%	100%
A4H4A1	Leishmania braziliensis	24%	100%
A4H5L7	Leishmania braziliensis	93%	100%
A4H641	Leishmania braziliensis	23%	100%
A4H9D1	Leishmania braziliensis	23%	100%
A4H9X5	Leishmania braziliensis	25%	100%
A4HA94	Leishmania braziliensis	27%	100%
A4HC27	Leishmania braziliensis	26%	100%
A4HG92	Leishmania braziliensis	23%	100%
A4HIM5	Leishmania braziliensis	21%	100%
A4HLJ9	Leishmania braziliensis	21%	100%
A4HMK7	Leishmania braziliensis	27%	72%
A4HNG3	Leishmania braziliensis	25%	100%
A4HNR5	Leishmania braziliensis	24%	100%
A4HNT2	Leishmania braziliensis	25%	90%
A4HQG8	Leishmania braziliensis	24%	100%
A4HSC0	Leishmania infantum	23%	100%
A4HSH7	Leishmania infantum	24%	100%
A4HTV4	Leishmania infantum	91%	89%
A4HTV5	Leishmania infantum	97%	87%
A4HUG1	Leishmania infantum	23%	100%
A4HX71	Leishmania infantum	23%	75%
A4HXQ3	Leishmania infantum	23%	100%
A4HYH4	Leishmania infantum	27%	100%
A4I3C6	Leishmania infantum	23%	100%
A4I564	Leishmania infantum	24%	100%
A4I5X0	Leishmania infantum	21%	100%
A4I910	Leishmania infantum	22%	100%
A4IB86	Leishmania infantum	28%	72%
A4IC54	Leishmania infantum	26%	100%
A4ICA4	Leishmania infantum	24%	100%
A4ICR2	Leishmania infantum	26%	91%
A4ICT0	Leishmania infantum	24%	100%
A9S9Q8	Physcomitrium patens	24%	100%
A9T142	Physcomitrium patens	26%	100%
B0XR80	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	24%	100%
B0Y462	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	25%	100%
B0Y4X4	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	26%	98%
B1H3E1	Xenopus tropicalis	26%	92%
B6DTC0	Bodo saltans	21%	100%
B6DTE5	Bodo saltans	25%	100%
B6DTK9	Bodo saltans	23%	100%
C9ZKU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	71%
C9ZR94	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZUD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZVD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A0U8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D0A105	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	81%
D0A230	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A2P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	94%
D0A3L9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A485	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	77%
D0A509	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A813	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	85%
D0A820	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A8X3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A9B7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	89%
D3ZSZ3	Rattus norvegicus	26%	79%
E1BMN8	Bos taurus	26%	78%
E2QWQ2	Canis lupus familiaris	26%	79%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AF07	Leishmania major	28%	72%
E9AFX4	Leishmania major	25%	100%
E9AGS0	Leishmania infantum	25%	100%
E9AKA2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AKG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AMP2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9AN59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9ARC8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	75%
E9ARG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ASJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	91%
E9AVG0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	83%
E9AZL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B164	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	100%
E9B3X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
E9B663	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	72%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
G4N374	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	25%	100%
G4NH08	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	24%	100%
G5EBT1	Caenorhabditis elegans	24%	82%
M1T7M3	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	25%	100%
O02812	Canis lupus familiaris	26%	100%
O04160	Brassica napus	24%	89%
O08605	Mus musculus	25%	97%
O08911	Mus musculus	27%	100%
O13352	Magnaporthe oryzae	25%	100%
O14047	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O15264	Homo sapiens	28%	100%
O23145	Arabidopsis thaliana	24%	97%
O23236	Arabidopsis thaliana	24%	100%
O35491	Mus musculus	35%	83%
O35493	Mus musculus	34%	86%
O35832	Rattus norvegicus	26%	92%
O42099	Cyprinus carpio	23%	97%
O43781	Homo sapiens	28%	71%
O44408	Caenorhabditis elegans	23%	100%
O44514	Caenorhabditis elegans	24%	88%
O54949	Mus musculus	26%	79%
O55173	Rattus norvegicus	28%	74%
O59853	Zygosaccharomyces rouxii	25%	99%
O59854	Zygosaccharomyces rouxii	25%	100%
O61443	Drosophila melanogaster	27%	100%
O93982	Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)	25%	97%
O94547	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	21%	72%
O94737	Pneumocystis carinii	21%	100%
O96526	Leishmania major	24%	100%
O96999	Leishmania major	23%	100%
P0C431	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	24%	100%
P0CP66	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	23%	100%
P0CP68	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	24%	100%
P0CP69	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	24%	100%
P11801	Homo sapiens	22%	98%
P14681	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P16892	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
P17157	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
P18265	Rattus norvegicus	23%	86%
P20793	Rattus norvegicus	26%	67%
P20794	Homo sapiens	25%	67%
P21708	Rattus norvegicus	26%	100%
P21965	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P22518	Mus musculus	38%	86%
P27361	Homo sapiens	26%	100%
P27638	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
P31152	Homo sapiens	23%	71%
P32485	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	96%
P34556	Caenorhabditis elegans	27%	100%
P38615	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P39745	Caenorhabditis elegans	24%	94%
P40417	Drosophila melanogaster	25%	100%
P41808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P42525	Dictyostelium discoideum	26%	79%
P45983	Homo sapiens	23%	97%
P45984	Homo sapiens	24%	98%
P47811	Mus musculus	26%	100%
P47812	Xenopus laevis	25%	100%
P49185	Rattus norvegicus	22%	100%
P49186	Rattus norvegicus	24%	98%
P49187	Rattus norvegicus	24%	90%
P49759	Homo sapiens	38%	86%
P49760	Homo sapiens	35%	83%
P49840	Homo sapiens	23%	86%
P50873	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	83%
P51136	Dictyostelium discoideum	25%	89%
P51138	Medicago sativa	22%	100%
P51139	Medicago sativa	24%	100%
P51566	Arabidopsis thaliana	36%	89%
P51567	Arabidopsis thaliana	35%	97%
P51568	Arabidopsis thaliana	39%	100%
P53778	Homo sapiens	28%	100%
P53779	Homo sapiens	24%	90%
P54666	Trypanosoma brucei brucei	24%	100%
P70618	Rattus norvegicus	26%	100%
P79996	Gallus gallus	23%	100%
Q00532	Homo sapiens	23%	100%
Q00534	Homo sapiens	24%	100%
Q00772	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	86%
Q04859	Mus musculus	26%	67%
Q06060	Pisum sativum	25%	100%
Q07176	Medicago sativa	26%	100%
Q09892	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q0CIC7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	25%	100%
Q0D0P5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	100%
Q0U4L8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	24%	100%
Q0V7M1	Bos taurus	22%	98%
Q10N20	Oryza sativa subsp. japonica	23%	100%
Q11179	Caenorhabditis elegans	24%	89%
Q12222	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q15759	Homo sapiens	27%	100%
Q16539	Homo sapiens	26%	100%
Q17446	Caenorhabditis elegans	27%	100%
Q17941	Caenorhabditis elegans	24%	77%
Q1DUU8	Coccidioides immitis (strain RS)	23%	100%
Q1KTF2	Zymoseptoria tritici (strain CBS 115943 / IPO323)	23%	100%
Q1L5Z8	Torulaspora delbrueckii	25%	97%
Q2H332	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	23%	100%
Q2U469	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	26%	100%
Q2WFL5	Cochliobolus miyabeanus	25%	100%
Q2WGK3	Trichoderma harzianum	24%	100%
Q336X9	Oryza sativa subsp. japonica	24%	100%
Q38HL5	Aspergillus glaucus	24%	100%
Q39021	Arabidopsis thaliana	24%	100%
Q39022	Arabidopsis thaliana	23%	100%
Q39023	Arabidopsis thaliana	23%	100%
Q39024	Arabidopsis thaliana	24%	100%
Q39025	Arabidopsis thaliana	24%	100%
Q39026	Arabidopsis thaliana	24%	100%
Q39027	Arabidopsis thaliana	24%	100%
Q3S406	Magnaporthe oryzae	24%	100%
Q3SX21	Bos taurus	35%	85%
Q3T0N5	Bos taurus	28%	100%
Q40353	Medicago sativa	24%	100%
Q40517	Nicotiana tabacum	25%	100%
Q40518	Nicotiana tabacum	23%	100%
Q40531	Nicotiana tabacum	26%	100%
Q40532	Nicotiana tabacum	25%	100%
Q40884	Petunia hybrida	24%	100%
Q45FA5	Physarum polycephalum	29%	98%
Q4G050	Rattus norvegicus	25%	100%
Q4PC06	Ustilago maydis (strain 521 / FGSC 9021)	24%	100%
Q4Q0B0	Leishmania major	24%	100%
Q4Q204	Leishmania major	26%	97%
Q4Q449	Leishmania major	22%	100%
Q4Q701	Leishmania major	21%	100%
Q4QAI6	Leishmania major	23%	69%
Q4QC19	Leishmania major	26%	100%
Q4QD66	Leishmania major	27%	100%
Q4QDK3	Leishmania major	25%	100%
Q4QE15	Leishmania major	23%	100%
Q4QEJ2	Leishmania major	23%	75%
Q4QFG6	Leishmania major	28%	100%
Q4QHG6	Leishmania major	23%	100%
Q4QHY3	Leishmania major	97%	100%
Q4QHY4	Leishmania major	89%	100%
Q4QJE7	Leishmania major	25%	100%
Q4R6S5	Macaca fascicularis	28%	73%
Q4R8T9	Macaca fascicularis	24%	71%
Q4V8A3	Rattus norvegicus	27%	71%
Q4W6D3	Cochliobolus heterostrophus	25%	100%
Q4WQR3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	98%
Q4WSF6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q4WUN7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q501Q9	Xenopus laevis	26%	71%
Q52PH6	Alternaria brassicicola	24%	100%
Q53N72	Oryza sativa subsp. japonica	25%	84%
Q54QB1	Dictyostelium discoideum	23%	100%
Q55C57	Dictyostelium discoideum	22%	88%
Q55FJ6	Dictyostelium discoideum	24%	82%
Q56R42	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	24%	100%
Q5A1D3	Candida albicans (strain SC5314 / ATCC MYA-2876)	22%	99%
Q5I6M2	Setosphaeria turcica	25%	100%
Q5J4W4	Oryza sativa subsp. japonica	24%	100%
Q5SN53	Oryza sativa subsp. japonica	25%	73%
Q5U4C9	Mus musculus	28%	69%
Q5VN19	Oryza sativa subsp. japonica	25%	73%
Q5VP69	Oryza sativa subsp. japonica	25%	83%
Q5Z7J0	Oryza sativa subsp. japonica	26%	100%
Q5Z859	Oryza sativa subsp. japonica	25%	100%
Q5Z9J0	Oryza sativa subsp. japonica	25%	72%
Q5ZCI1	Oryza sativa subsp. japonica	26%	68%
Q5ZIU3	Gallus gallus	28%	79%
Q61831	Mus musculus	23%	90%
Q62726	Rattus norvegicus	24%	66%
Q63117	Rattus norvegicus	35%	85%
Q63538	Rattus norvegicus	27%	100%
Q63844	Mus musculus	25%	100%
Q64261	Mus musculus	24%	100%
Q66JF3	Xenopus tropicalis	25%	100%
Q67C40	Oryza sativa subsp. japonica	26%	73%
Q6C4M9	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	100%
Q6CJA8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	94%
Q6FIU2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	93%
Q6FKD4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	27%	100%
Q6L5F7	Oryza sativa subsp. japonica	25%	71%
Q6P5G0	Mus musculus	24%	71%
Q6PWX2	Beauveria bassiana	24%	100%
Q6XKY3	Hypocrea atroviridis	24%	100%
Q6Z437	Oryza sativa subsp. japonica	24%	100%
Q6Z8C8	Oryza sativa subsp. japonica	26%	91%
Q702W0	Blastobotrys adeninivorans	26%	100%
Q750A9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	93%
Q751E8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	100%
Q75KK8	Oryza sativa subsp. japonica	25%	77%
Q75Q66	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	24%	100%
Q80Y86	Mus musculus	27%	76%
Q84M93	Arabidopsis thaliana	25%	86%
Q84SN3	Oryza sativa subsp. japonica	25%	96%
Q84UI5	Oryza sativa subsp. japonica	26%	100%
Q875L0	Cryphonectria parasitica	24%	100%
Q8BGW6	Mus musculus	25%	100%
Q8CEQ0	Mus musculus	22%	100%
Q8GYQ5	Arabidopsis thaliana	23%	100%
Q8IVW4	Homo sapiens	24%	70%
Q8LF80	Arabidopsis thaliana	24%	100%
Q8MXI4	Caenorhabditis elegans	26%	99%
Q8NJT7	Hortaea werneckii	24%	100%
Q8QGV6	Xenopus laevis	26%	93%
Q8QHK8	Xenopus laevis	22%	98%
Q8SQW2	Encephalitozoon cuniculi (strain GB-M1)	22%	100%
Q8SR86	Encephalitozoon cuniculi (strain GB-M1)	25%	100%
Q8TD08	Homo sapiens	27%	76%
Q8TGA9	Blumeria graminis	23%	100%
Q8W4J2	Arabidopsis thaliana	27%	73%
Q8WQ45	Leishmania donovani	24%	100%
Q8WQG9	Caenorhabditis elegans	26%	90%
Q8WU08	Homo sapiens	26%	100%
Q90327	Cyprinus carpio	23%	97%
Q90336	Cyprinus carpio	27%	100%
Q91Y86	Mus musculus	23%	100%
Q92207	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	100%
Q92241	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	26%	100%
Q922Y0	Mus musculus	27%	71%
Q92398	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	99%
Q92630	Homo sapiens	28%	69%
Q95NE7	Pan troglodytes	26%	100%
Q96287	Arabidopsis thaliana	24%	88%
Q966Y3	Suberites domuncula	24%	100%
Q96QS6	Homo sapiens	24%	100%
Q96TL5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q96VK3	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	76%
Q9C5C0	Arabidopsis thaliana	24%	68%
Q9C9U4	Arabidopsis thaliana	23%	72%
Q9DGD9	Danio rerio	23%	100%
Q9DGE1	Danio rerio	27%	100%
Q9DGE2	Danio rerio	27%	100%
Q9FVS6	Arabidopsis thaliana	22%	99%
Q9GRU1	Leishmania mexicana	27%	100%
Q9HAZ1	Homo sapiens	34%	86%
Q9HG11	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	100%
Q9I958	Cyprinus carpio	27%	100%
Q9JKV2	Mus musculus	25%	66%
Q9JM01	Rattus norvegicus	24%	70%
Q9LM33	Arabidopsis thaliana	27%	71%
Q9LMM5	Arabidopsis thaliana	26%	100%
Q9LQQ9	Arabidopsis thaliana	22%	100%
Q9LUC3	Arabidopsis thaliana	27%	70%
Q9LV37	Arabidopsis thaliana	27%	82%
Q9M1Z5	Arabidopsis thaliana	24%	100%
Q9N272	Pan troglodytes	27%	100%
Q9N2N1	Leishmania major	23%	100%
Q9NR20	Homo sapiens	28%	80%
Q9P419	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	23%	100%
Q9SJG9	Arabidopsis thaliana	26%	69%
Q9U6D2	Ancylostoma caninum	26%	100%
Q9U6V4	Leishmania donovani	27%	100%
Q9UBE8	Homo sapiens	26%	79%
Q9UQ07	Homo sapiens	22%	99%
Q9URT9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	26%	100%
Q9UV51	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	23%	100%
Q9WTU6	Mus musculus	24%	98%
Q9WTY9	Rattus norvegicus	28%	100%
Q9WUI1	Mus musculus	26%	100%
Q9XTG7	Caenorhabditis elegans	22%	79%
Q9Y463	Homo sapiens	31%	66%
Q9Z188	Mus musculus	31%	66%
Q9Z1B7	Mus musculus	28%	100%
Q9Z2A0	Mus musculus	28%	74%
Q9Z2A6	Rattus norvegicus	27%	76%
V5B6E9	Trypanosoma cruzi	23%	100%
V5B8S3	Trypanosoma cruzi	27%	90%
V5B8U8	Trypanosoma cruzi	27%	100%
V5B9Y9	Trypanosoma cruzi	24%	92%
V5BCX5	Trypanosoma cruzi	22%	100%
V5BG98	Trypanosoma cruzi	25%	100%
V5BH88	Trypanosoma cruzi	23%	76%
V5BLT9	Trypanosoma cruzi	22%	100%
V5BN23	Trypanosoma cruzi	78%	84%
V5BPE2	Trypanosoma cruzi	26%	100%
V5BSG8	Trypanosoma cruzi	26%	100%
V5BUV8	Trypanosoma cruzi	26%	76%
V5BV49	Trypanosoma cruzi	24%	100%
V5DCD4	Trypanosoma cruzi	24%	71%
V5DDT1	Trypanosoma cruzi	24%	100%
V5DIC3	Trypanosoma cruzi	24%	69%
V5DTI8	Trypanosoma cruzi	25%	100%