Uncharacterized protein LmxM_27_1380a_1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHJ9_LEIMU

TriTrypDb:

LmxM.27.1380a

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

E8NHJ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHJ9

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	1
GO:0022613	ribonucleoprotein complex biogenesis	4	1
GO:0042254	ribosome biogenesis	5	1
GO:0044085	cellular component biogenesis	3	1
GO:0071840	cellular component organization or biogenesis	2	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	50	54	PF00656	0.532
CLV_PCSK_SKI1_1	131	135	PF00082	0.291
CLV_PCSK_SKI1_1	31	35	PF00082	0.370
CLV_PCSK_SKI1_1	43	47	PF00082	0.247
CLV_PCSK_SKI1_1	80	84	PF00082	0.462
DEG_Nend_Nbox_1	1	2	PF02207	0.616
DEG_SPOP_SBC_1	117	121	PF00917	0.616
DOC_CYCLIN_RxL_1	128	137	PF00134	0.532
DOC_MAPK_gen_1	31	39	PF00069	0.530
DOC_MAPK_MEF2A_6	131	138	PF00069	0.532
DOC_PP1_RVXF_1	78	85	PF00149	0.501
DOC_USP7_MATH_1	117	121	PF00917	0.598
DOC_USP7_MATH_1	177	181	PF00917	0.574
DOC_USP7_MATH_1	186	190	PF00917	0.562
DOC_USP7_MATH_1	9	13	PF00917	0.616
DOC_WW_Pin1_4	63	68	PF00397	0.597
LIG_BRCT_BRCA1_1	140	144	PF00533	0.532
LIG_FHA_1	54	60	PF00498	0.532
LIG_FHA_2	11	17	PF00498	0.532
LIG_FHA_2	138	144	PF00498	0.532
LIG_FHA_2	83	89	PF00498	0.517
LIG_GBD_Chelix_1	28	36	PF00786	0.332
LIG_IRF3_LxIS_1	59	66	PF10401	0.532
LIG_LIR_Gen_1	20	29	PF02991	0.532
LIG_LIR_Nem_3	128	133	PF02991	0.532
LIG_LIR_Nem_3	20	26	PF02991	0.507
LIG_LIR_Nem_3	66	72	PF02991	0.457
LIG_NBox_RRM_1	22	32	PF00076	0.532
LIG_PCNA_yPIPBox_3	71	80	PF02747	0.505
LIG_SH3_3	173	179	PF00018	0.616
LIG_SH3_3	3	9	PF00018	0.532
LIG_SUMO_SIM_par_1	132	137	PF11976	0.491
LIG_SUMO_SIM_par_1	35	42	PF11976	0.532
LIG_SUMO_SIM_par_1	73	79	PF11976	0.462
LIG_TRAF2_1	182	185	PF00917	0.532
MOD_CK1_1	137	143	PF00069	0.527
MOD_CK1_1	55	61	PF00069	0.527
MOD_CK2_1	10	16	PF00069	0.532
MOD_CK2_1	137	143	PF00069	0.532
MOD_GlcNHglycan	157	160	PF01048	0.416
MOD_GlcNHglycan	163	166	PF01048	0.341
MOD_GlcNHglycan	179	182	PF01048	0.416
MOD_GSK3_1	134	141	PF00069	0.520
MOD_N-GLC_1	53	58	PF02516	0.332
MOD_N-GLC_1	63	68	PF02516	0.397
MOD_NEK2_1	134	139	PF00069	0.520
MOD_NEK2_1	161	166	PF00069	0.583
MOD_PIKK_1	15	21	PF00454	0.530
MOD_Plk_4	18	24	PF00069	0.532
MOD_Plk_4	55	61	PF00069	0.532
MOD_Plk_4	73	79	PF00069	0.495
MOD_ProDKin_1	63	69	PF00069	0.602
MOD_SUMO_rev_2	38	46	PF00179	0.492
TRG_ENDOCYTIC_2	69	72	PF00928	0.498
TRG_Pf-PMV_PEXEL_1	150	154	PF00026	0.332
TRG_Pf-PMV_PEXEL_1	98	102	PF00026	0.638

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2F2	Leptomonas seymouri	81%	68%
Q8SRJ7	Encephalitozoon cuniculi (strain GB-M1)	41%	75%
Q9Y8J3	Methanococcus voltae	34%	67%