Uncharacterized protein LmxM_20_1370a_1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHJ4_LEIMU

TriTrypDb:

LmxM.20.1370a

Length:

346

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E8NHJ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHJ4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0003723	RNA binding	4	3
GO:0005488	binding	1	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.309
CLV_NRD_NRD_1	136	138	PF00675	0.398
CLV_NRD_NRD_1	19	21	PF00675	0.552
CLV_NRD_NRD_1	24	26	PF00675	0.633
CLV_NRD_NRD_1	242	244	PF00675	0.586
CLV_NRD_NRD_1	251	253	PF00675	0.467
CLV_PCSK_KEX2_1	136	138	PF00082	0.398
CLV_PCSK_KEX2_1	19	21	PF00082	0.552
CLV_PCSK_KEX2_1	242	244	PF00082	0.586
CLV_PCSK_KEX2_1	251	253	PF00082	0.467
CLV_PCSK_SKI1_1	168	172	PF00082	0.597
CLV_PCSK_SKI1_1	297	301	PF00082	0.243
CLV_Separin_Metazoa	294	298	PF03568	0.243
DEG_APCC_DBOX_1	241	249	PF00400	0.574
DEG_APCC_DBOX_1	296	304	PF00400	0.243
DOC_MAPK_gen_1	193	201	PF00069	0.243
DOC_MAPK_MEF2A_6	193	201	PF00069	0.243
DOC_PP4_FxxP_1	46	49	PF00568	0.683
DOC_WW_Pin1_4	161	166	PF00397	0.316
DOC_WW_Pin1_4	50	55	PF00397	0.758
LIG_14-3-3_CanoR_1	151	158	PF00244	0.326
LIG_14-3-3_CanoR_1	19	23	PF00244	0.531
LIG_14-3-3_CanoR_1	242	246	PF00244	0.298
LIG_14-3-3_CanoR_1	325	331	PF00244	0.386
LIG_14-3-3_CanoR_1	38	47	PF00244	0.542
LIG_Actin_WH2_1	179	197	PF00022	0.307
LIG_Actin_WH2_2	180	197	PF00022	0.306
LIG_BIR_II_1	1	5	PF00653	0.631
LIG_FHA_1	133	139	PF00498	0.511
LIG_FHA_1	217	223	PF00498	0.243
LIG_FHA_2	207	213	PF00498	0.527
LIG_LIR_Apic_2	45	49	PF02991	0.629
LIG_LIR_Nem_3	309	314	PF02991	0.314
LIG_SH2_STAT3	314	317	PF00017	0.369
LIG_SH2_STAT5	12	15	PF00017	0.487
LIG_SH2_STAT5	240	243	PF00017	0.380
LIG_SH2_STAT5	269	272	PF00017	0.288
LIG_SH3_3	121	127	PF00018	0.565
LIG_SH3_3	44	50	PF00018	0.548
LIG_SH3_3	54	60	PF00018	0.746
LIG_WW_3	48	52	PF00397	0.532
MOD_CDK_SPxxK_3	161	168	PF00069	0.311
MOD_CK1_1	185	191	PF00069	0.317
MOD_CK1_1	238	244	PF00069	0.307
MOD_CK1_1	28	34	PF00069	0.664
MOD_CK1_1	323	329	PF00069	0.378
MOD_CK1_1	62	68	PF00069	0.567
MOD_CK2_1	206	212	PF00069	0.527
MOD_CK2_1	244	250	PF00069	0.294
MOD_GlcNHglycan	138	141	PF01048	0.472
MOD_GlcNHglycan	255	259	PF01048	0.306
MOD_GlcNHglycan	27	30	PF01048	0.688
MOD_GlcNHglycan	3	6	PF01048	0.689
MOD_GSK3_1	110	117	PF00069	0.581
MOD_GSK3_1	132	139	PF00069	0.461
MOD_GSK3_1	14	21	PF00069	0.538
MOD_GSK3_1	212	219	PF00069	0.243
MOD_GSK3_1	234	241	PF00069	0.586
MOD_GSK3_1	28	35	PF00069	0.739
MOD_GSK3_1	316	323	PF00069	0.260
MOD_GSK3_1	82	89	PF00069	0.565
MOD_N-GLC_2	233	235	PF02516	0.276
MOD_NEK2_1	226	231	PF00069	0.430
MOD_NEK2_1	234	239	PF00069	0.543
MOD_NEK2_1	270	275	PF00069	0.573
MOD_NEK2_1	32	37	PF00069	0.569
MOD_PIKK_1	174	180	PF00454	0.331
MOD_PIKK_1	235	241	PF00454	0.591
MOD_PIKK_1	270	276	PF00454	0.568
MOD_PKA_1	136	142	PF00069	0.381
MOD_PKA_1	25	31	PF00069	0.552
MOD_PKA_2	136	142	PF00069	0.381
MOD_PKA_2	150	156	PF00069	0.286
MOD_PKA_2	18	24	PF00069	0.552
MOD_PKA_2	241	247	PF00069	0.293
MOD_PKA_2	324	330	PF00069	0.390
MOD_PKA_2	82	88	PF00069	0.544
MOD_Plk_1	254	260	PF00069	0.297
MOD_Plk_4	166	172	PF00069	0.371
MOD_Plk_4	182	188	PF00069	0.264
MOD_Plk_4	226	232	PF00069	0.296
MOD_Plk_4	244	250	PF00069	0.254
MOD_Plk_4	42	48	PF00069	0.625
MOD_ProDKin_1	161	167	PF00069	0.312
MOD_ProDKin_1	50	56	PF00069	0.759
TRG_ER_diArg_1	136	138	PF00400	0.398
TRG_ER_diArg_1	192	195	PF00400	0.315
TRG_NES_CRM1_1	189	200	PF08389	0.400
TRG_NES_CRM1_1	298	309	PF08389	0.257
TRG_Pf-PMV_PEXEL_1	208	212	PF00026	0.527

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H4H3	Leishmania braziliensis	35%	72%