LeishMANIAdb
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Uncharacterized protein LmxM_33_1890_1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein LmxM_33_1890_1
Gene product:
tuzin-like protein
Species:
Leishmania mexicana
UniProt:
E8NHI6_LEIMU
TriTrypDb:
LmxM.33.1890
Length:
282

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

E8NHI6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 128 130 PF00675 0.413
CLV_NRD_NRD_1 2 4 PF00675 0.316
CLV_NRD_NRD_1 268 270 PF00675 0.272
CLV_NRD_NRD_1 68 70 PF00675 0.481
CLV_PCSK_KEX2_1 127 129 PF00082 0.414
CLV_PCSK_KEX2_1 2 4 PF00082 0.316
CLV_PCSK_KEX2_1 268 270 PF00082 0.272
CLV_PCSK_KEX2_1 70 72 PF00082 0.463
CLV_PCSK_PC1ET2_1 70 72 PF00082 0.441
CLV_PCSK_SKI1_1 202 206 PF00082 0.343
DEG_Nend_UBRbox_1 1 4 PF02207 0.517
DOC_CYCLIN_RxL_1 199 207 PF00134 0.547
DOC_MAPK_MEF2A_6 225 234 PF00069 0.531
DOC_PP2B_LxvP_1 198 201 PF13499 0.575
DOC_USP7_MATH_1 35 39 PF00917 0.551
DOC_WW_Pin1_4 58 63 PF00397 0.674
DOC_WW_Pin1_4 64 69 PF00397 0.633
LIG_14-3-3_CanoR_1 142 146 PF00244 0.634
LIG_14-3-3_CanoR_1 259 264 PF00244 0.448
LIG_14-3-3_CanoR_1 26 30 PF00244 0.570
LIG_14-3-3_CanoR_1 71 76 PF00244 0.654
LIG_Clathr_ClatBox_1 134 138 PF01394 0.605
LIG_DLG_GKlike_1 71 78 PF00625 0.632
LIG_EH1_1 162 170 PF00400 0.599
LIG_FHA_1 152 158 PF00498 0.638
LIG_FHA_1 174 180 PF00498 0.575
LIG_LIR_Gen_1 174 181 PF02991 0.548
LIG_LIR_Nem_3 174 180 PF02991 0.547
LIG_LIR_Nem_3 262 266 PF02991 0.435
LIG_NRBOX 74 80 PF00104 0.626
LIG_Pex14_2 235 239 PF04695 0.549
LIG_SH2_PTP2 177 180 PF00017 0.549
LIG_SH2_STAP1 110 114 PF00017 0.592
LIG_SH2_STAT5 110 113 PF00017 0.639
LIG_SH2_STAT5 177 180 PF00017 0.549
LIG_SH3_3 218 224 PF00018 0.528
LIG_SH3_3 81 87 PF00018 0.632
LIG_SH3_CIN85_PxpxPR_1 64 69 PF14604 0.666
LIG_SUMO_SIM_anti_2 176 183 PF11976 0.578
LIG_SUMO_SIM_anti_2 228 234 PF11976 0.535
LIG_SUMO_SIM_par_1 133 138 PF11976 0.606
LIG_UBA3_1 164 170 PF00899 0.568
MOD_CDC14_SPxK_1 67 70 PF00782 0.659
MOD_CDK_SPK_2 64 69 PF00069 0.666
MOD_CDK_SPxK_1 64 70 PF00069 0.664
MOD_CDK_SPxxK_3 64 71 PF00069 0.661
MOD_CK1_1 103 109 PF00069 0.598
MOD_CK1_1 25 31 PF00069 0.577
MOD_CK1_1 273 279 PF00069 0.473
MOD_GlcNHglycan 159 162 PF01048 0.406
MOD_GlcNHglycan 182 185 PF01048 0.346
MOD_GlcNHglycan 206 209 PF01048 0.343
MOD_GlcNHglycan 235 238 PF01048 0.328
MOD_GlcNHglycan 272 275 PF01048 0.262
MOD_GlcNHglycan 37 40 PF01048 0.323
MOD_GSK3_1 268 275 PF00069 0.531
MOD_GSK3_1 82 89 PF00069 0.606
MOD_NEK2_1 164 169 PF00069 0.571
MOD_NEK2_1 204 209 PF00069 0.535
MOD_PKA_1 268 274 PF00069 0.458
MOD_PKA_2 141 147 PF00069 0.633
MOD_PKA_2 25 31 PF00069 0.577
MOD_PKA_2 268 274 PF00069 0.466
MOD_PKB_1 69 77 PF00069 0.637
MOD_Plk_1 106 112 PF00069 0.578
MOD_Plk_1 173 179 PF00069 0.546
MOD_Plk_1 186 192 PF00069 0.513
MOD_Plk_4 164 170 PF00069 0.580
MOD_Plk_4 173 179 PF00069 0.521
MOD_Plk_4 25 31 PF00069 0.549
MOD_Plk_4 86 92 PF00069 0.610
MOD_ProDKin_1 58 64 PF00069 0.674
TRG_DiLeu_BaEn_1 228 233 PF01217 0.542
TRG_DiLeu_BaEn_1 242 247 PF01217 0.479
TRG_ENDOCYTIC_2 177 180 PF00928 0.549
TRG_ER_diArg_1 1 3 PF00400 0.517
TRG_ER_diArg_1 127 129 PF00400 0.614
TRG_ER_diArg_1 267 269 PF00400 0.452
TRG_ER_diArg_1 68 71 PF00400 0.676
TRG_NLS_MonoExtN_4 66 73 PF00514 0.651

Homologs

Protein Taxonomy Sequence identity Coverage
E8NHF6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 68%
E8NHR9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 99% 68%
E8NHS6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 99% 68%
E9AMF6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 79%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS