WGS CADB00000000 data, contig 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E8NHE6_LEIMU

TriTrypDb:

LmxM.22.1690partial

Length:

384

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E8NHE6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E8NHE6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	46	50	PF00656	0.668
CLV_NRD_NRD_1	218	220	PF00675	0.445
CLV_NRD_NRD_1	235	237	PF00675	0.549
CLV_NRD_NRD_1	240	242	PF00675	0.521
CLV_NRD_NRD_1	255	257	PF00675	0.528
CLV_NRD_NRD_1	259	261	PF00675	0.534
CLV_NRD_NRD_1	287	289	PF00675	0.513
CLV_NRD_NRD_1	303	305	PF00675	0.497
CLV_NRD_NRD_1	343	345	PF00675	0.463
CLV_NRD_NRD_1	39	41	PF00675	0.492
CLV_NRD_NRD_1	57	59	PF00675	0.511
CLV_NRD_NRD_1	80	82	PF00675	0.409
CLV_PCSK_FUR_1	39	43	PF00082	0.478
CLV_PCSK_FUR_1	55	59	PF00082	0.425
CLV_PCSK_KEX2_1	220	222	PF00082	0.440
CLV_PCSK_KEX2_1	233	235	PF00082	0.536
CLV_PCSK_KEX2_1	240	242	PF00082	0.506
CLV_PCSK_KEX2_1	255	257	PF00082	0.533
CLV_PCSK_KEX2_1	259	261	PF00082	0.530
CLV_PCSK_KEX2_1	287	289	PF00082	0.513
CLV_PCSK_KEX2_1	303	305	PF00082	0.497
CLV_PCSK_KEX2_1	343	345	PF00082	0.463
CLV_PCSK_KEX2_1	39	41	PF00082	0.506
CLV_PCSK_KEX2_1	55	57	PF00082	0.599
CLV_PCSK_KEX2_1	80	82	PF00082	0.409
CLV_PCSK_PC1ET2_1	220	222	PF00082	0.352
CLV_PCSK_PC1ET2_1	233	235	PF00082	0.358
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.498
CLV_PCSK_PC7_1	236	242	PF00082	0.437
CLV_PCSK_PC7_1	255	261	PF00082	0.451
CLV_PCSK_PC7_1	299	305	PF00082	0.488
CLV_PCSK_SKI1_1	250	254	PF00082	0.437
CLV_PCSK_SKI1_1	80	84	PF00082	0.504
DOC_CYCLIN_yCln2_LP_2	242	248	PF00134	0.609
DOC_PP1_RVXF_1	290	297	PF00149	0.548
DOC_PP4_FxxP_1	59	62	PF00568	0.677
DOC_USP7_MATH_1	119	123	PF00917	0.682
DOC_USP7_MATH_1	146	150	PF00917	0.678
DOC_USP7_MATH_1	173	177	PF00917	0.710
DOC_USP7_MATH_1	200	204	PF00917	0.654
DOC_USP7_MATH_1	251	255	PF00917	0.697
DOC_USP7_MATH_1	268	272	PF00917	0.730
DOC_USP7_MATH_1	314	318	PF00917	0.744
DOC_USP7_MATH_1	327	331	PF00917	0.689
DOC_USP7_MATH_1	34	38	PF00917	0.676
DOC_USP7_MATH_1	370	374	PF00917	0.649
DOC_USP7_MATH_1	47	51	PF00917	0.626
DOC_USP7_MATH_1	99	103	PF00917	0.793
DOC_WW_Pin1_4	325	330	PF00397	0.649
LIG_14-3-3_CanoR_1	234	242	PF00244	0.602
LIG_14-3-3_CanoR_1	272	276	PF00244	0.611
LIG_14-3-3_CanoR_1	304	314	PF00244	0.719
LIG_14-3-3_CterR_2	380	384	PF00244	0.667
LIG_BIR_II_1	1	4	PF00653	0.287
LIG_BIR_III_2	104	108	PF00653	0.678
LIG_BIR_III_2	131	135	PF00653	0.667
LIG_BIR_III_2	158	162	PF00653	0.702
LIG_BIR_III_2	185	189	PF00653	0.659
LIG_BIR_III_2	20	24	PF00653	0.680
LIG_BIR_III_2	8	12	PF00653	0.646
LIG_Clathr_ClatBox_1	100	104	PF01394	0.674
LIG_Clathr_ClatBox_1	4	8	PF01394	0.287
LIG_FHA_2	11	17	PF00498	0.654
LIG_FHA_2	134	140	PF00498	0.769
LIG_FHA_2	161	167	PF00498	0.764
LIG_FHA_2	188	194	PF00498	0.664
LIG_FHA_2	41	47	PF00498	0.671
LIG_Pex14_2	225	229	PF04695	0.546
LIG_SH3_1	343	349	PF00018	0.651
LIG_SH3_2	245	250	PF14604	0.622
LIG_SH3_3	104	110	PF00018	0.679
LIG_SH3_3	115	121	PF00018	0.681
LIG_SH3_3	142	148	PF00018	0.703
LIG_SH3_3	169	175	PF00018	0.806
LIG_SH3_3	196	202	PF00018	0.668
LIG_SH3_3	242	248	PF00018	0.609
LIG_SH3_3	261	267	PF00018	0.722
LIG_SH3_3	317	323	PF00018	0.686
LIG_SH3_3	336	342	PF00018	0.665
LIG_SH3_3	343	349	PF00018	0.662
LIG_SH3_3	68	74	PF00018	0.691
LIG_SH3_CIN85_PxpxPR_1	72	77	PF14604	0.629
LIG_SUMO_SIM_par_1	2	8	PF11976	0.287
LIG_SUMO_SIM_par_1	99	104	PF11976	0.766
LIG_TRAF2_1	90	93	PF00917	0.636
MOD_CK1_1	271	277	PF00069	0.597
MOD_CK1_1	305	311	PF00069	0.640
MOD_CK1_1	48	54	PF00069	0.574
MOD_CK1_1	86	92	PF00069	0.538
MOD_CK2_1	10	16	PF00069	0.552
MOD_CK2_1	133	139	PF00069	0.713
MOD_CK2_1	160	166	PF00069	0.654
MOD_CK2_1	187	193	PF00069	0.567
MOD_CK2_1	305	311	PF00069	0.509
MOD_CK2_1	354	360	PF00069	0.545
MOD_GlcNHglycan	307	310	PF01048	0.640
MOD_GlcNHglycan	349	352	PF01048	0.559
MOD_GlcNHglycan	372	375	PF01048	0.555
MOD_GlcNHglycan	85	88	PF01048	0.615
MOD_GSK3_1	251	258	PF00069	0.593
MOD_GSK3_1	314	321	PF00069	0.684
MOD_GSK3_1	354	361	PF00069	0.563
MOD_N-GLC_1	325	330	PF02516	0.549
MOD_NEK2_1	354	359	PF00069	0.544
MOD_NEK2_2	34	39	PF00069	0.587
MOD_PIKK_1	314	320	PF00454	0.551
MOD_PIKK_1	354	360	PF00454	0.545
MOD_PIKK_1	92	98	PF00454	0.546
MOD_PKA_1	235	241	PF00069	0.440
MOD_PKA_1	255	261	PF00069	0.552
MOD_PKA_1	40	46	PF00069	0.583
MOD_PKA_1	57	63	PF00069	0.511
MOD_PKA_2	235	241	PF00069	0.440
MOD_PKA_2	255	261	PF00069	0.552
MOD_PKA_2	271	277	PF00069	0.507
MOD_PKA_2	302	308	PF00069	0.623
MOD_PKA_2	57	63	PF00069	0.585
MOD_PKA_2	83	89	PF00069	0.499
MOD_PKB_1	221	229	PF00069	0.406
MOD_PKB_1	234	242	PF00069	0.443
MOD_PKB_1	55	63	PF00069	0.586
MOD_Plk_1	48	54	PF00069	0.699
MOD_Plk_4	48	54	PF00069	0.574
MOD_ProDKin_1	325	331	PF00069	0.550
TRG_DiLeu_BaLyEn_6	296	301	PF01217	0.579
TRG_ER_diArg_1	219	222	PF00400	0.534
TRG_ER_diArg_1	234	236	PF00400	0.678
TRG_ER_diArg_1	240	242	PF00400	0.632
TRG_ER_diArg_1	275	278	PF00400	0.466
TRG_ER_diArg_1	286	288	PF00400	0.387
TRG_ER_diArg_1	302	304	PF00400	0.609
TRG_ER_diArg_1	342	344	PF00400	0.565
TRG_ER_diArg_1	38	40	PF00400	0.721
TRG_ER_diArg_1	54	57	PF00400	0.546
TRG_ER_diArg_1	79	81	PF00400	0.491
TRG_NLS_Bipartite_1	219	237	PF00514	0.411
TRG_NLS_MonoCore_2	232	237	PF00514	0.418
TRG_NLS_MonoExtC_3	218	223	PF00514	0.417
TRG_NLS_MonoExtC_3	39	44	PF00514	0.589
TRG_NLS_MonoExtN_4	39	44	PF00514	0.589
TRG_Pf-PMV_PEXEL_1	3	8	PF00026	0.287
TRG_Pf-PMV_PEXEL_1	61	66	PF00026	0.590

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HRS0	Leishmania infantum	42%	89%
E9AH09	Leishmania infantum	42%	89%