LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IE51_LEIIN
TriTrypDb:
LINF_360051400
Length:
611

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IE51
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE51

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 153 157 PF00656 0.581
CLV_C14_Caspase3-7 310 314 PF00656 0.803
CLV_MEL_PAP_1 576 582 PF00089 0.590
CLV_NRD_NRD_1 108 110 PF00675 0.475
CLV_NRD_NRD_1 16 18 PF00675 0.628
CLV_NRD_NRD_1 221 223 PF00675 0.629
CLV_NRD_NRD_1 288 290 PF00675 0.800
CLV_NRD_NRD_1 35 37 PF00675 0.706
CLV_NRD_NRD_1 384 386 PF00675 0.771
CLV_NRD_NRD_1 448 450 PF00675 0.707
CLV_NRD_NRD_1 505 507 PF00675 0.579
CLV_NRD_NRD_1 546 548 PF00675 0.580
CLV_NRD_NRD_1 94 96 PF00675 0.691
CLV_PCSK_FUR_1 14 18 PF00082 0.618
CLV_PCSK_FUR_1 382 386 PF00082 0.668
CLV_PCSK_KEX2_1 108 110 PF00082 0.619
CLV_PCSK_KEX2_1 154 156 PF00082 0.619
CLV_PCSK_KEX2_1 16 18 PF00082 0.628
CLV_PCSK_KEX2_1 221 223 PF00082 0.629
CLV_PCSK_KEX2_1 288 290 PF00082 0.800
CLV_PCSK_KEX2_1 35 37 PF00082 0.653
CLV_PCSK_KEX2_1 384 386 PF00082 0.771
CLV_PCSK_KEX2_1 409 411 PF00082 0.796
CLV_PCSK_KEX2_1 413 415 PF00082 0.681
CLV_PCSK_KEX2_1 448 450 PF00082 0.711
CLV_PCSK_KEX2_1 505 507 PF00082 0.579
CLV_PCSK_KEX2_1 94 96 PF00082 0.594
CLV_PCSK_PC1ET2_1 154 156 PF00082 0.619
CLV_PCSK_PC1ET2_1 409 411 PF00082 0.796
CLV_PCSK_PC1ET2_1 413 415 PF00082 0.681
CLV_PCSK_PC7_1 217 223 PF00082 0.583
CLV_PCSK_SKI1_1 138 142 PF00082 0.508
CLV_PCSK_SKI1_1 155 159 PF00082 0.433
CLV_PCSK_SKI1_1 406 410 PF00082 0.698
CLV_PCSK_SKI1_1 548 552 PF00082 0.621
CLV_PCSK_SKI1_1 564 568 PF00082 0.503
DEG_APCC_DBOX_1 546 554 PF00400 0.571
DEG_MDM2_SWIB_1 168 176 PF02201 0.506
DEG_Nend_UBRbox_2 1 3 PF02207 0.703
DEG_SCF_FBW7_1 350 357 PF00400 0.649
DEG_SPOP_SBC_1 249 253 PF00917 0.711
DEG_SPOP_SBC_1 258 262 PF00917 0.690
DOC_CKS1_1 351 356 PF01111 0.713
DOC_CYCLIN_RxL_1 545 554 PF00134 0.643
DOC_MAPK_gen_1 108 115 PF00069 0.647
DOC_MAPK_gen_1 323 332 PF00069 0.615
DOC_MAPK_gen_1 382 392 PF00069 0.678
DOC_MAPK_gen_1 547 555 PF00069 0.555
DOC_MAPK_MEF2A_6 547 555 PF00069 0.528
DOC_SPAK_OSR1_1 579 583 PF12202 0.545
DOC_USP7_MATH_1 187 191 PF00917 0.641
DOC_USP7_MATH_1 249 253 PF00917 0.717
DOC_USP7_MATH_1 257 261 PF00917 0.686
DOC_USP7_MATH_1 268 272 PF00917 0.783
DOC_USP7_MATH_1 278 282 PF00917 0.721
DOC_USP7_MATH_1 292 296 PF00917 0.639
DOC_USP7_MATH_1 307 311 PF00917 0.514
DOC_USP7_MATH_1 312 316 PF00917 0.674
DOC_USP7_MATH_1 354 358 PF00917 0.747
DOC_USP7_MATH_1 370 374 PF00917 0.761
DOC_USP7_MATH_1 378 382 PF00917 0.667
DOC_USP7_MATH_1 394 398 PF00917 0.632
DOC_USP7_MATH_1 469 473 PF00917 0.721
DOC_USP7_MATH_1 520 524 PF00917 0.703
DOC_USP7_UBL2_3 409 413 PF12436 0.692
DOC_WW_Pin1_4 126 131 PF00397 0.644
DOC_WW_Pin1_4 177 182 PF00397 0.635
DOC_WW_Pin1_4 189 194 PF00397 0.652
DOC_WW_Pin1_4 202 207 PF00397 0.625
DOC_WW_Pin1_4 251 256 PF00397 0.726
DOC_WW_Pin1_4 274 279 PF00397 0.812
DOC_WW_Pin1_4 305 310 PF00397 0.617
DOC_WW_Pin1_4 325 330 PF00397 0.793
DOC_WW_Pin1_4 338 343 PF00397 0.701
DOC_WW_Pin1_4 350 355 PF00397 0.715
DOC_WW_Pin1_4 357 362 PF00397 0.462
DOC_WW_Pin1_4 364 369 PF00397 0.605
DOC_WW_Pin1_4 50 55 PF00397 0.709
DOC_WW_Pin1_4 516 521 PF00397 0.667
LIG_14-3-3_CanoR_1 173 182 PF00244 0.685
LIG_14-3-3_CanoR_1 250 255 PF00244 0.680
LIG_14-3-3_CanoR_1 356 360 PF00244 0.657
LIG_14-3-3_CanoR_1 384 394 PF00244 0.713
LIG_14-3-3_CanoR_1 448 457 PF00244 0.764
LIG_14-3-3_CanoR_1 94 100 PF00244 0.570
LIG_APCC_ABBAyCdc20_2 548 554 PF00400 0.614
LIG_BIR_III_2 306 310 PF00653 0.593
LIG_Clathr_ClatBox_1 550 554 PF01394 0.508
LIG_CSL_BTD_1 181 184 PF09270 0.570
LIG_deltaCOP1_diTrp_1 71 77 PF00928 0.615
LIG_FHA_1 114 120 PF00498 0.529
LIG_FHA_1 410 416 PF00498 0.627
LIG_FHA_1 441 447 PF00498 0.785
LIG_FHA_1 597 603 PF00498 0.588
LIG_FHA_2 151 157 PF00498 0.592
LIG_FHA_2 22 28 PF00498 0.602
LIG_FHA_2 402 408 PF00498 0.619
LIG_FHA_2 429 435 PF00498 0.549
LIG_FHA_2 496 502 PF00498 0.590
LIG_FHA_2 567 573 PF00498 0.559
LIG_FHA_2 63 69 PF00498 0.627
LIG_LIR_Gen_1 165 176 PF02991 0.435
LIG_LIR_Gen_1 431 440 PF02991 0.553
LIG_LIR_Nem_3 165 171 PF02991 0.427
LIG_LIR_Nem_3 180 185 PF02991 0.668
LIG_LIR_Nem_3 422 428 PF02991 0.687
LIG_Pex14_2 164 168 PF04695 0.482
LIG_PTB_Apo_2 427 434 PF02174 0.687
LIG_PTB_Phospho_1 427 433 PF10480 0.683
LIG_RPA_C_Fungi 379 391 PF08784 0.673
LIG_RPA_C_Fungi 444 456 PF08784 0.597
LIG_SH2_PTP2 552 555 PF00017 0.497
LIG_SH2_SRC 552 555 PF00017 0.497
LIG_SH2_STAT5 114 117 PF00017 0.493
LIG_SH2_STAT5 166 169 PF00017 0.427
LIG_SH2_STAT5 487 490 PF00017 0.679
LIG_SH2_STAT5 552 555 PF00017 0.497
LIG_SH2_STAT5 568 571 PF00017 0.525
LIG_SH3_3 178 184 PF00018 0.752
LIG_SH3_3 190 196 PF00018 0.629
LIG_SH3_3 306 312 PF00018 0.594
LIG_SH3_3 341 347 PF00018 0.695
LIG_SH3_3 348 354 PF00018 0.708
LIG_SH3_3 536 542 PF00018 0.728
LIG_SH3_3 543 549 PF00018 0.642
LIG_SH3_3 552 558 PF00018 0.369
LIG_SH3_CIN85_PxpxPR_1 340 345 PF14604 0.634
LIG_SH3_CIN85_PxpxPR_1 542 547 PF14604 0.677
LIG_TYR_ITIM 550 555 PF00017 0.503
MOD_CDK_SPK_2 126 131 PF00069 0.582
MOD_CDK_SPK_2 189 194 PF00069 0.620
MOD_CDK_SPK_2 357 362 PF00069 0.729
MOD_CDK_SPK_2 516 521 PF00069 0.667
MOD_CDK_SPxK_1 350 356 PF00069 0.650
MOD_CDK_SPxxK_3 338 345 PF00069 0.670
MOD_CK1_1 150 156 PF00069 0.600
MOD_CK1_1 192 198 PF00069 0.647
MOD_CK1_1 240 246 PF00069 0.690
MOD_CK1_1 248 254 PF00069 0.640
MOD_CK1_1 277 283 PF00069 0.813
MOD_CK1_1 328 334 PF00069 0.674
MOD_CK1_1 357 363 PF00069 0.706
MOD_CK1_1 401 407 PF00069 0.678
MOD_CK1_1 439 445 PF00069 0.693
MOD_CK1_1 451 457 PF00069 0.565
MOD_CK1_1 528 534 PF00069 0.762
MOD_CK2_1 21 27 PF00069 0.612
MOD_CK2_1 257 263 PF00069 0.710
MOD_CK2_1 268 274 PF00069 0.583
MOD_CK2_1 281 287 PF00069 0.545
MOD_CK2_1 401 407 PF00069 0.617
MOD_CK2_1 428 434 PF00069 0.711
MOD_CK2_1 495 501 PF00069 0.717
MOD_CMANNOS 74 77 PF00535 0.510
MOD_DYRK1A_RPxSP_1 516 520 PF00069 0.660
MOD_GlcNHglycan 239 242 PF01048 0.705
MOD_GlcNHglycan 244 247 PF01048 0.699
MOD_GlcNHglycan 255 258 PF01048 0.681
MOD_GlcNHglycan 270 273 PF01048 0.742
MOD_GlcNHglycan 274 277 PF01048 0.744
MOD_GlcNHglycan 283 286 PF01048 0.619
MOD_GlcNHglycan 333 337 PF01048 0.799
MOD_GlcNHglycan 36 39 PF01048 0.730
MOD_GlcNHglycan 376 379 PF01048 0.665
MOD_GlcNHglycan 450 453 PF01048 0.601
MOD_GlcNHglycan 483 486 PF01048 0.668
MOD_GlcNHglycan 530 533 PF01048 0.675
MOD_GlcNHglycan 536 539 PF01048 0.665
MOD_GSK3_1 232 239 PF00069 0.598
MOD_GSK3_1 245 252 PF00069 0.757
MOD_GSK3_1 253 260 PF00069 0.653
MOD_GSK3_1 268 275 PF00069 0.751
MOD_GSK3_1 277 284 PF00069 0.648
MOD_GSK3_1 307 314 PF00069 0.710
MOD_GSK3_1 321 328 PF00069 0.636
MOD_GSK3_1 350 357 PF00069 0.675
MOD_GSK3_1 360 367 PF00069 0.586
MOD_GSK3_1 370 377 PF00069 0.627
MOD_GSK3_1 380 387 PF00069 0.440
MOD_GSK3_1 394 401 PF00069 0.595
MOD_GSK3_1 436 443 PF00069 0.703
MOD_GSK3_1 451 458 PF00069 0.641
MOD_GSK3_1 495 502 PF00069 0.599
MOD_GSK3_1 516 523 PF00069 0.707
MOD_NEK2_1 125 130 PF00069 0.525
MOD_NEK2_1 299 304 PF00069 0.698
MOD_NEK2_1 386 391 PF00069 0.695
MOD_NEK2_1 399 404 PF00069 0.688
MOD_NEK2_1 440 445 PF00069 0.776
MOD_NEK2_1 586 591 PF00069 0.534
MOD_PIKK_1 460 466 PF00454 0.643
MOD_PIKK_1 514 520 PF00454 0.687
MOD_PK_1 95 101 PF00069 0.706
MOD_PKA_1 384 390 PF00069 0.739
MOD_PKA_1 409 415 PF00069 0.688
MOD_PKA_1 448 454 PF00069 0.600
MOD_PKA_2 249 255 PF00069 0.737
MOD_PKA_2 287 293 PF00069 0.738
MOD_PKA_2 34 40 PF00069 0.610
MOD_PKA_2 355 361 PF00069 0.695
MOD_PKA_2 384 390 PF00069 0.735
MOD_PKA_2 409 415 PF00069 0.789
MOD_PKA_2 448 454 PF00069 0.627
MOD_PKA_2 455 461 PF00069 0.648
MOD_PKA_2 469 475 PF00069 0.607
MOD_PKA_2 520 526 PF00069 0.706
MOD_PKA_2 578 584 PF00069 0.606
MOD_PKA_2 85 91 PF00069 0.606
MOD_PKB_1 382 390 PF00069 0.675
MOD_Plk_1 155 161 PF00069 0.528
MOD_Plk_1 421 427 PF00069 0.651
MOD_Plk_4 167 173 PF00069 0.492
MOD_Plk_4 428 434 PF00069 0.650
MOD_Plk_4 69 75 PF00069 0.482
MOD_ProDKin_1 126 132 PF00069 0.639
MOD_ProDKin_1 177 183 PF00069 0.645
MOD_ProDKin_1 189 195 PF00069 0.651
MOD_ProDKin_1 202 208 PF00069 0.623
MOD_ProDKin_1 251 257 PF00069 0.727
MOD_ProDKin_1 274 280 PF00069 0.814
MOD_ProDKin_1 305 311 PF00069 0.620
MOD_ProDKin_1 325 331 PF00069 0.793
MOD_ProDKin_1 338 344 PF00069 0.698
MOD_ProDKin_1 350 356 PF00069 0.717
MOD_ProDKin_1 357 363 PF00069 0.460
MOD_ProDKin_1 364 370 PF00069 0.605
MOD_ProDKin_1 50 56 PF00069 0.708
MOD_ProDKin_1 516 522 PF00069 0.672
MOD_SUMO_rev_2 401 411 PF00179 0.698
TRG_DiLeu_BaLyEn_6 546 551 PF01217 0.647
TRG_ENDOCYTIC_2 433 436 PF00928 0.555
TRG_ENDOCYTIC_2 552 555 PF00928 0.497
TRG_ER_diArg_1 108 111 PF00400 0.450
TRG_ER_diArg_1 13 16 PF00400 0.619
TRG_ER_diArg_1 382 385 PF00400 0.708
TRG_ER_diArg_1 504 506 PF00400 0.571
TRG_ER_diArg_1 93 95 PF00400 0.685
TRG_NES_CRM1_1 133 146 PF08389 0.615

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0U0 Leptomonas seymouri 39% 96%
A0A3Q8IJR0 Leishmania donovani 100% 100%
A4HPU1 Leishmania braziliensis 68% 99%
E9ATK6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 95%
Q4Q0Z2 Leishmania major 91% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS