Sucraseferredoxin family protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Sucrase/ferredoxin-like - putative

Species:

Leishmania infantum

UniProt:

A4IE29_LEIIN

TriTrypDb:

LINF_360071800

Length:

270

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0016020	membrane	2	1

Expansion

Sequence features

A4IE29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE29

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	84	86	PF00082	0.389
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.389
CLV_PCSK_PC7_1	80	86	PF00082	0.355
CLV_PCSK_SKI1_1	188	192	PF00082	0.448
DEG_Nend_UBRbox_4	1	3	PF02207	0.574
DOC_USP7_MATH_1	104	108	PF00917	0.356
DOC_USP7_UBL2_3	125	129	PF12436	0.258
LIG_14-3-3_CanoR_1	202	206	PF00244	0.433
LIG_14-3-3_CanoR_1	27	35	PF00244	0.533
LIG_eIF4E_1	178	184	PF01652	0.336
LIG_FHA_1	151	157	PF00498	0.472
LIG_FHA_1	8	14	PF00498	0.573
LIG_FHA_1	84	90	PF00498	0.352
LIG_FHA_2	32	38	PF00498	0.469
LIG_LIR_Apic_2	141	147	PF02991	0.450
LIG_LIR_Gen_1	161	170	PF02991	0.419
LIG_LIR_Gen_1	22	30	PF02991	0.557
LIG_LIR_Nem_3	135	140	PF02991	0.352
LIG_LIR_Nem_3	159	165	PF02991	0.343
LIG_LIR_Nem_3	22	26	PF02991	0.548
LIG_SH2_CRK	137	141	PF00017	0.357
LIG_SH2_STAT5	162	165	PF00017	0.412
LIG_SH2_STAT5	178	181	PF00017	0.205
LIG_SH3_3	137	143	PF00018	0.429
LIG_SUMO_SIM_par_1	152	157	PF11976	0.472
LIG_TYR_ITSM	133	140	PF00017	0.370
MOD_CK1_1	138	144	PF00069	0.376
MOD_CK1_1	168	174	PF00069	0.390
MOD_CK2_1	63	69	PF00069	0.527
MOD_GlcNHglycan	137	140	PF01048	0.364
MOD_GlcNHglycan	157	161	PF01048	0.418
MOD_GSK3_1	104	111	PF00069	0.423
MOD_GSK3_1	15	22	PF00069	0.562
MOD_GSK3_1	5	12	PF00069	0.680
MOD_NEK2_1	108	113	PF00069	0.396
MOD_NEK2_1	165	170	PF00069	0.370
MOD_NEK2_1	7	12	PF00069	0.626
MOD_NEK2_1	72	77	PF00069	0.391
MOD_NEK2_2	63	68	PF00069	0.555
MOD_PIKK_1	132	138	PF00454	0.342
MOD_PIKK_1	7	13	PF00454	0.685
MOD_PKA_2	201	207	PF00069	0.413
MOD_Plk_1	104	110	PF00069	0.363
MOD_Plk_1	117	123	PF00069	0.396
MOD_Plk_2-3	114	120	PF00069	0.394
MOD_Plk_2-3	19	25	PF00069	0.553
MOD_Plk_4	117	123	PF00069	0.363
MOD_Plk_4	178	184	PF00069	0.390
MOD_Plk_4	201	207	PF00069	0.258
MOD_SUMO_for_1	234	237	PF00179	0.450
MOD_SUMO_rev_2	127	132	PF00179	0.399
MOD_SUMO_rev_2	145	153	PF00179	0.400
MOD_SUMO_rev_2	244	252	PF00179	0.394
TRG_DiLeu_BaEn_2	160	166	PF01217	0.352
TRG_ENDOCYTIC_2	137	140	PF00928	0.357
TRG_ENDOCYTIC_2	162	165	PF00928	0.450
TRG_ENDOCYTIC_2	231	234	PF00928	0.433
TRG_NES_CRM1_1	145	157	PF08389	0.394

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8U1	Leptomonas seymouri	42%	100%
A0A0N1I8X6	Leptomonas seymouri	74%	100%
A0A0S4JXX0	Bodo saltans	44%	100%
A0A1X0NM84	Trypanosomatidae	47%	100%
A0A3Q8IGR7	Leishmania donovani	100%	100%
A0A422NAD6	Trypanosoma rangeli	47%	100%
A4HQD8	Leishmania braziliensis	81%	100%
D0A3V9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	94%
E9AU53	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q0E2	Leishmania major	93%	100%
V5DJZ4	Trypanosoma cruzi	49%	82%