LeishMANIAdb
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TYR_PHOSPHATASE_2 domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
TYR_PHOSPHATASE_2 domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IE25_LEIIN
TriTrypDb:
LINF_360071400
Length:
744

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IE25
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE25

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 131 135 PF00656 0.611
CLV_C14_Caspase3-7 161 165 PF00656 0.738
CLV_NRD_NRD_1 200 202 PF00675 0.598
CLV_NRD_NRD_1 252 254 PF00675 0.699
CLV_NRD_NRD_1 275 277 PF00675 0.669
CLV_NRD_NRD_1 284 286 PF00675 0.595
CLV_NRD_NRD_1 389 391 PF00675 0.642
CLV_NRD_NRD_1 469 471 PF00675 0.733
CLV_NRD_NRD_1 605 607 PF00675 0.562
CLV_NRD_NRD_1 641 643 PF00675 0.621
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IMJ9 Leptomonas seymouri 33% 84%
A0A3S7XC30 Leishmania donovani 97% 97%
A4HQD3 Leishmania braziliensis 57% 100%
E9AU49 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q0E6 Leishmania major 88% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS