L6202.3-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

l6202.3-like protein

Species:

Leishmania infantum

UniProt:

A4IE13_LEIIN

TriTrypDb:

LINF_360069900

Length:

851

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IE13

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	160	164	PF00656	0.507
CLV_C14_Caspase3-7	250	254	PF00656	0.476
CLV_C14_Caspase3-7	313	317	PF00656	0.511
CLV_C14_Caspase3-7	841	845	PF00656	0.531
CLV_MEL_PAP_1	528	534	PF00089	0.446
CLV_NRD_NRD_1	186	188	PF00675	0.521
CLV_NRD_NRD_1	232	234	PF00675	0.525
CLV_NRD_NRD_1	245	247	PF00675	0.381
CLV_NRD_NRD_1	274	276	PF00675	0.478
CLV_NRD_NRD_1	301	303	PF00675	0.456
CLV_NRD_NRD_1	477	479	PF00675	0.538
CLV_NRD_NRD_1	530	532	PF00675	0.450
CLV_NRD_NRD_1	614	616	PF00675	0.515
CLV_NRD_NRD_1	618	620	PF00675	0.495
CLV_NRD_NRD_1	691	693	PF00675	0.539
CLV_NRD_NRD_1	736	738	PF00675	0.666
CLV_NRD_NRD_1	746	748	PF00675	0.589
CLV_NRD_NRD_1	755	757	PF00675	0.519
CLV_PCSK_FUR_1	230	234	PF00082	0.524
CLV_PCSK_FUR_1	692	696	PF00082	0.524
CLV_PCSK_KEX2_1	185	187	PF00082	0.532
CLV_PCSK_KEX2_1	232	234	PF00082	0.525
CLV_PCSK_KEX2_1	245	247	PF00082	0.381
CLV_PCSK_KEX2_1	274	276	PF00082	0.496
CLV_PCSK_KEX2_1	301	303	PF00082	0.437
CLV_PCSK_KEX2_1	477	479	PF00082	0.538
CLV_PCSK_KEX2_1	530	532	PF00082	0.449
CLV_PCSK_KEX2_1	614	616	PF00082	0.482
CLV_PCSK_KEX2_1	620	622	PF00082	0.422
CLV_PCSK_KEX2_1	691	693	PF00082	0.608
CLV_PCSK_KEX2_1	694	696	PF00082	0.618
CLV_PCSK_KEX2_1	704	706	PF00082	0.607
CLV_PCSK_KEX2_1	736	738	PF00082	0.666
CLV_PCSK_KEX2_1	746	748	PF00082	0.589
CLV_PCSK_KEX2_1	755	757	PF00082	0.519
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.472
CLV_PCSK_PC1ET2_1	620	622	PF00082	0.424
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.609
CLV_PCSK_PC1ET2_1	704	706	PF00082	0.583
CLV_PCSK_PC7_1	182	188	PF00082	0.500
CLV_PCSK_PC7_1	732	738	PF00082	0.654
CLV_PCSK_SKI1_1	145	149	PF00082	0.491
CLV_PCSK_SKI1_1	182	186	PF00082	0.464
CLV_PCSK_SKI1_1	260	264	PF00082	0.457
CLV_PCSK_SKI1_1	293	297	PF00082	0.494
CLV_PCSK_SKI1_1	301	305	PF00082	0.552
CLV_PCSK_SKI1_1	327	331	PF00082	0.485
CLV_PCSK_SKI1_1	33	37	PF00082	0.541
CLV_PCSK_SKI1_1	407	411	PF00082	0.595
CLV_PCSK_SKI1_1	505	509	PF00082	0.608
CLV_PCSK_SKI1_1	694	698	PF00082	0.624
CLV_PCSK_SKI1_1	705	709	PF00082	0.594
CLV_PCSK_SKI1_1	747	751	PF00082	0.690
DEG_SPOP_SBC_1	428	432	PF00917	0.606
DEG_SPOP_SBC_1	667	671	PF00917	0.529
DOC_CDC14_PxL_1	773	781	PF14671	0.595
DOC_CKS1_1	759	764	PF01111	0.540
DOC_CYCLIN_RxL_1	182	193	PF00134	0.533
DOC_CYCLIN_RxL_1	298	307	PF00134	0.422
DOC_MAPK_gen_1	182	190	PF00069	0.537
DOC_MAPK_gen_1	337	346	PF00069	0.587
DOC_MAPK_gen_1	383	391	PF00069	0.536
DOC_MAPK_gen_1	530	536	PF00069	0.481
DOC_MAPK_gen_1	582	590	PF00069	0.551
DOC_MAPK_gen_1	691	701	PF00069	0.522
DOC_MAPK_MEF2A_6	337	346	PF00069	0.556
DOC_MAPK_MEF2A_6	385	393	PF00069	0.497
DOC_MAPK_MEF2A_6	59	68	PF00069	0.508
DOC_PP1_RVXF_1	258	264	PF00149	0.388
DOC_PP2B_LxvP_1	843	846	PF13499	0.527
DOC_USP7_MATH_1	197	201	PF00917	0.473
DOC_USP7_MATH_1	335	339	PF00917	0.517
DOC_USP7_MATH_1	374	378	PF00917	0.577
DOC_USP7_MATH_1	4	8	PF00917	0.628
DOC_USP7_MATH_1	421	425	PF00917	0.620
DOC_USP7_MATH_1	428	432	PF00917	0.581
DOC_USP7_MATH_1	50	54	PF00917	0.494
DOC_USP7_MATH_1	509	513	PF00917	0.589
DOC_USP7_MATH_1	538	542	PF00917	0.520
DOC_USP7_MATH_1	684	688	PF00917	0.592
DOC_USP7_MATH_1	720	724	PF00917	0.607
DOC_USP7_MATH_1	788	792	PF00917	0.693
DOC_USP7_MATH_1	800	804	PF00917	0.591
DOC_USP7_UBL2_3	694	698	PF12436	0.621
DOC_USP7_UBL2_3	704	708	PF12436	0.576
DOC_WW_Pin1_4	357	362	PF00397	0.650
DOC_WW_Pin1_4	424	429	PF00397	0.668
DOC_WW_Pin1_4	675	680	PF00397	0.713
DOC_WW_Pin1_4	707	712	PF00397	0.726
DOC_WW_Pin1_4	758	763	PF00397	0.641
LIG_14-3-3_CanoR_1	10	18	PF00244	0.554
LIG_14-3-3_CanoR_1	145	150	PF00244	0.657
LIG_14-3-3_CanoR_1	186	191	PF00244	0.500
LIG_14-3-3_CanoR_1	222	227	PF00244	0.515
LIG_14-3-3_CanoR_1	245	249	PF00244	0.472
LIG_14-3-3_CanoR_1	355	359	PF00244	0.648
LIG_14-3-3_CanoR_1	444	450	PF00244	0.600
LIG_14-3-3_CanoR_1	45	54	PF00244	0.499
LIG_14-3-3_CanoR_1	457	465	PF00244	0.473
LIG_14-3-3_CanoR_1	505	514	PF00244	0.590
LIG_14-3-3_CanoR_1	537	543	PF00244	0.577
LIG_14-3-3_CanoR_1	546	556	PF00244	0.494
LIG_14-3-3_CanoR_1	73	79	PF00244	0.517
LIG_14-3-3_CanoR_1	756	762	PF00244	0.632
LIG_Actin_WH2_2	442	459	PF00022	0.464
LIG_Actin_WH2_2	528	545	PF00022	0.447
LIG_APCC_ABBA_1	832	837	PF00400	0.542
LIG_BIR_II_1	1	5	PF00653	0.617
LIG_BIR_III_3	1	5	PF00653	0.579
LIG_CaM_IQ_9	174	189	PF13499	0.495
LIG_FHA_1	13	19	PF00498	0.507
LIG_FHA_1	144	150	PF00498	0.507
LIG_FHA_1	328	334	PF00498	0.635
LIG_FHA_1	408	414	PF00498	0.685
LIG_FHA_1	477	483	PF00498	0.456
LIG_FHA_1	520	526	PF00498	0.619
LIG_FHA_1	548	554	PF00498	0.604
LIG_FHA_1	565	571	PF00498	0.337
LIG_FHA_1	668	674	PF00498	0.559
LIG_FHA_1	708	714	PF00498	0.742
LIG_FHA_1	728	734	PF00498	0.633
LIG_FHA_1	748	754	PF00498	0.753
LIG_FHA_1	759	765	PF00498	0.654
LIG_FHA_1	828	834	PF00498	0.590
LIG_FHA_2	136	142	PF00498	0.419
LIG_FHA_2	223	229	PF00498	0.516
LIG_FHA_2	245	251	PF00498	0.474
LIG_FHA_2	311	317	PF00498	0.507
LIG_FHA_2	758	764	PF00498	0.631
LIG_LIR_Gen_1	168	177	PF02991	0.460
LIG_LIR_Gen_1	573	581	PF02991	0.429
LIG_LIR_Nem_3	168	173	PF02991	0.489
LIG_LIR_Nem_3	573	578	PF02991	0.552
LIG_LIR_Nem_3	771	776	PF02991	0.590
LIG_LYPXL_S_1	772	776	PF13949	0.530
LIG_LYPXL_yS_3	773	776	PF13949	0.527
LIG_MYND_1	646	650	PF01753	0.579
LIG_MYND_3	776	780	PF01753	0.598
LIG_SH2_STAP1	470	474	PF00017	0.526
LIG_SH2_STAP1	785	789	PF00017	0.557
LIG_SH2_STAT3	120	123	PF00017	0.532
LIG_SH2_STAT3	470	473	PF00017	0.524
LIG_SH2_STAT5	203	206	PF00017	0.514
LIG_SH3_3	355	361	PF00018	0.644
LIG_SH3_3	362	368	PF00018	0.636
LIG_SH3_3	673	679	PF00018	0.527
LIG_SH3_3	771	777	PF00018	0.576
LIG_Sin3_3	682	689	PF02671	0.589
LIG_SUMO_SIM_anti_2	763	769	PF11976	0.584
LIG_SUMO_SIM_par_1	61	67	PF11976	0.471
LIG_TRAF2_1	138	141	PF00917	0.507
LIG_TRAF2_1	24	27	PF00917	0.511
LIG_TRAF2_1	247	250	PF00917	0.468
LIG_TRAF2_1	370	373	PF00917	0.632
LIG_TRAF2_1	817	820	PF00917	0.665
MOD_CK1_1	165	171	PF00069	0.529
MOD_CK1_1	357	363	PF00069	0.740
MOD_CK1_1	401	407	PF00069	0.564
MOD_CK1_1	424	430	PF00069	0.656
MOD_CK1_1	431	437	PF00069	0.610
MOD_CK1_1	445	451	PF00069	0.440
MOD_CK1_1	452	458	PF00069	0.567
MOD_CK1_1	48	54	PF00069	0.471
MOD_CK1_1	541	547	PF00069	0.448
MOD_CK1_1	725	731	PF00069	0.629
MOD_CK1_1	735	741	PF00069	0.701
MOD_CK1_1	77	83	PF00069	0.412
MOD_CK1_1	791	797	PF00069	0.762
MOD_CK1_1	826	832	PF00069	0.763
MOD_CK2_1	135	141	PF00069	0.419
MOD_CK2_1	165	171	PF00069	0.545
MOD_CK2_1	222	228	PF00069	0.524
MOD_CK2_1	244	250	PF00069	0.483
MOD_CK2_1	284	290	PF00069	0.479
MOD_CK2_1	335	341	PF00069	0.442
MOD_CK2_1	38	44	PF00069	0.530
MOD_CK2_1	66	72	PF00069	0.479
MOD_GlcNHglycan	18	21	PF01048	0.512
MOD_GlcNHglycan	253	256	PF01048	0.633
MOD_GlcNHglycan	417	420	PF01048	0.598
MOD_GlcNHglycan	423	426	PF01048	0.568
MOD_GlcNHglycan	438	441	PF01048	0.452
MOD_GlcNHglycan	670	673	PF01048	0.663
MOD_GlcNHglycan	790	793	PF01048	0.578
MOD_GlcNHglycan	796	799	PF01048	0.586
MOD_GlcNHglycan	803	806	PF01048	0.650
MOD_GlcNHglycan	808	812	PF01048	0.689
MOD_GSK3_1	12	19	PF00069	0.530
MOD_GSK3_1	186	193	PF00069	0.499
MOD_GSK3_1	218	225	PF00069	0.398
MOD_GSK3_1	34	41	PF00069	0.535
MOD_GSK3_1	357	364	PF00069	0.754
MOD_GSK3_1	4	11	PF00069	0.633
MOD_GSK3_1	424	431	PF00069	0.640
MOD_GSK3_1	445	452	PF00069	0.613
MOD_GSK3_1	501	508	PF00069	0.509
MOD_GSK3_1	541	548	PF00069	0.513
MOD_GSK3_1	552	559	PF00069	0.404
MOD_GSK3_1	636	643	PF00069	0.628
MOD_GSK3_1	654	661	PF00069	0.612
MOD_GSK3_1	703	710	PF00069	0.689
MOD_GSK3_1	727	734	PF00069	0.730
MOD_GSK3_1	735	742	PF00069	0.643
MOD_GSK3_1	747	754	PF00069	0.826
MOD_GSK3_1	790	797	PF00069	0.693
MOD_GSK3_1	823	830	PF00069	0.627
MOD_N-GLC_1	216	221	PF02516	0.450
MOD_N-GLC_1	526	531	PF02516	0.490
MOD_N-GLC_1	667	672	PF02516	0.602
MOD_N-GLC_1	739	744	PF02516	0.646
MOD_NEK2_1	135	140	PF00069	0.419
MOD_NEK2_1	190	195	PF00069	0.525
MOD_NEK2_1	34	39	PF00069	0.501
MOD_NEK2_1	389	394	PF00069	0.543
MOD_NEK2_1	456	461	PF00069	0.458
MOD_NEK2_1	634	639	PF00069	0.598
MOD_NEK2_2	104	109	PF00069	0.537
MOD_NEK2_2	538	543	PF00069	0.520
MOD_NEK2_2	768	773	PF00069	0.553
MOD_PIKK_1	310	316	PF00454	0.504
MOD_PIKK_1	34	40	PF00454	0.488
MOD_PIKK_1	359	365	PF00454	0.745
MOD_PIKK_1	476	482	PF00454	0.494
MOD_PIKK_1	48	54	PF00454	0.421
MOD_PIKK_1	509	515	PF00454	0.587
MOD_PIKK_1	658	664	PF00454	0.597
MOD_PIKK_1	739	745	PF00454	0.681
MOD_PK_1	582	588	PF00069	0.475
MOD_PKA_1	186	192	PF00069	0.497
MOD_PKA_2	186	192	PF00069	0.497
MOD_PKA_2	244	250	PF00069	0.468
MOD_PKA_2	354	360	PF00069	0.674
MOD_PKA_2	452	458	PF00069	0.521
MOD_PKA_2	476	482	PF00069	0.532
MOD_PKA_2	545	551	PF00069	0.462
MOD_PKA_2	731	737	PF00069	0.663
MOD_PKA_2	754	760	PF00069	0.582
MOD_PKA_2	838	844	PF00069	0.644
MOD_PKA_2	9	15	PF00069	0.558
MOD_PKB_1	652	660	PF00069	0.560
MOD_PKB_1	737	745	PF00069	0.596
MOD_Plk_1	165	171	PF00069	0.529
MOD_Plk_1	197	203	PF00069	0.478
MOD_Plk_1	582	588	PF00069	0.490
MOD_Plk_1	590	596	PF00069	0.431
MOD_Plk_4	165	171	PF00069	0.559
MOD_Plk_4	50	56	PF00069	0.489
MOD_Plk_4	722	728	PF00069	0.727
MOD_Plk_4	768	774	PF00069	0.528
MOD_Plk_4	838	844	PF00069	0.659
MOD_ProDKin_1	357	363	PF00069	0.651
MOD_ProDKin_1	424	430	PF00069	0.667
MOD_ProDKin_1	675	681	PF00069	0.711
MOD_ProDKin_1	707	713	PF00069	0.727
MOD_ProDKin_1	758	764	PF00069	0.639
MOD_SUMO_for_1	395	398	PF00179	0.577
MOD_SUMO_rev_2	458	466	PF00179	0.545
MOD_SUMO_rev_2	486	491	PF00179	0.467
TRG_AP2beta_CARGO_1	573	582	PF09066	0.491
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.483
TRG_DiLeu_BaLyEn_6	566	571	PF01217	0.414
TRG_DiLeu_BaLyEn_6	644	649	PF01217	0.611
TRG_ENDOCYTIC_2	773	776	PF00928	0.590
TRG_ER_diArg_1	186	188	PF00400	0.521
TRG_ER_diArg_1	230	233	PF00400	0.523
TRG_ER_diArg_1	274	277	PF00400	0.481
TRG_ER_diArg_1	300	302	PF00400	0.460
TRG_ER_diArg_1	336	339	PF00400	0.567
TRG_ER_diArg_1	383	386	PF00400	0.535
TRG_ER_diArg_1	530	532	PF00400	0.450
TRG_ER_diArg_1	614	616	PF00400	0.485
TRG_ER_diArg_1	618	621	PF00400	0.458
TRG_ER_diArg_1	736	739	PF00400	0.606
TRG_NES_CRM1_1	568	583	PF08389	0.492
TRG_NLS_MonoExtC_3	618	624	PF00514	0.516
TRG_NLS_MonoExtN_4	182	189	PF00514	0.499
TRG_Pf-PMV_PEXEL_1	186	191	PF00026	0.567
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.543
TRG_Pf-PMV_PEXEL_1	301	305	PF00026	0.516
TRG_Pf-PMV_PEXEL_1	45	49	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	569	573	PF00026	0.431

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFI1	Leptomonas seymouri	40%	88%
A0A3S7XC59	Leishmania donovani	100%	100%
A4HQB9	Leishmania braziliensis	58%	100%
E9AU35	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4Q0G0	Leishmania major	87%	100%