LeishMANIAdb
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Cytidine deaminase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Cytidine deaminase
Gene product:
A distinct subfamily of CDD/CDA-like deaminases - putative
Species:
Leishmania infantum
UniProt:
A4IE07_LEIIN
TriTrypDb:
LINF_360069300 *
Length:
339

Annotations

Annotations by Jardim et al.

Pyrimidine metabolism, Cytidine_deaminase-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IE07
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE07

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 196 200 PF00656 0.500
CLV_C14_Caspase3-7 321 325 PF00656 0.519
CLV_NRD_NRD_1 159 161 PF00675 0.383
CLV_NRD_NRD_1 221 223 PF00675 0.386
CLV_NRD_NRD_1 285 287 PF00675 0.383
CLV_NRD_NRD_1 309 311 PF00675 0.500
CLV_PCSK_KEX2_1 221 223 PF00082 0.500
CLV_PCSK_KEX2_1 285 287 PF00082 0.383
CLV_PCSK_SKI1_1 259 263 PF00082 0.383
CLV_PCSK_SKI1_1 266 270 PF00082 0.383
CLV_PCSK_SKI1_1 285 289 PF00082 0.383
CLV_PCSK_SKI1_1 311 315 PF00082 0.500
CLV_PCSK_SKI1_1 63 67 PF00082 0.459
DEG_Nend_UBRbox_2 1 3 PF02207 0.745
DEG_SCF_FBW7_1 209 215 PF00400 0.500
DEG_SCF_FBW7_1 231 237 PF00400 0.383
DOC_CKS1_1 209 214 PF01111 0.500
DOC_CKS1_1 231 236 PF01111 0.383
DOC_MAPK_gen_1 221 227 PF00069 0.395
DOC_MAPK_gen_1 310 317 PF00069 0.395
DOC_MAPK_MEF2A_6 310 317 PF00069 0.383
DOC_PP1_RVXF_1 308 315 PF00149 0.500
DOC_PP2B_LxvP_1 251 254 PF13499 0.579
DOC_PP2B_LxvP_1 315 318 PF13499 0.500
DOC_USP7_MATH_1 155 159 PF00917 0.324
DOC_USP7_MATH_1 212 216 PF00917 0.362
DOC_USP7_MATH_1 234 238 PF00917 0.344
DOC_USP7_MATH_1 35 39 PF00917 0.494
DOC_WW_Pin1_4 208 213 PF00397 0.500
DOC_WW_Pin1_4 230 235 PF00397 0.383
DOC_WW_Pin1_4 305 310 PF00397 0.500
LIG_14-3-3_CanoR_1 145 151 PF00244 0.413
LIG_14-3-3_CanoR_1 166 176 PF00244 0.383
LIG_14-3-3_CanoR_1 238 245 PF00244 0.383
LIG_Actin_WH2_2 272 287 PF00022 0.383
LIG_FHA_1 123 129 PF00498 0.538
LIG_FHA_1 142 148 PF00498 0.150
LIG_FHA_1 168 174 PF00498 0.383
LIG_FHA_1 253 259 PF00498 0.383
LIG_FHA_1 286 292 PF00498 0.383
LIG_FHA_1 51 57 PF00498 0.602
LIG_FHA_1 60 66 PF00498 0.435
LIG_FHA_2 172 178 PF00498 0.383
LIG_FHA_2 191 197 PF00498 0.383
LIG_FHA_2 22 28 PF00498 0.600
LIG_FHA_2 314 320 PF00498 0.500
LIG_FHA_2 86 92 PF00498 0.554
LIG_LIR_Gen_1 123 131 PF02991 0.627
LIG_LIR_Gen_1 49 57 PF02991 0.599
LIG_LIR_Gen_1 98 108 PF02991 0.596
LIG_LIR_Nem_3 123 129 PF02991 0.529
LIG_LIR_Nem_3 174 178 PF02991 0.500
LIG_LIR_Nem_3 49 54 PF02991 0.591
LIG_LIR_Nem_3 98 103 PF02991 0.594
LIG_NRP_CendR_1 337 339 PF00754 0.676
LIG_Pex14_1 47 51 PF04695 0.566
LIG_PTB_Apo_2 269 276 PF02174 0.383
LIG_PTB_Apo_2 30 37 PF02174 0.610
LIG_SH3_1 161 167 PF00018 0.500
LIG_SH3_3 161 167 PF00018 0.500
LIG_SH3_3 270 276 PF00018 0.383
LIG_SH3_3 77 83 PF00018 0.609
LIG_SUMO_SIM_anti_2 53 59 PF11976 0.612
LIG_TRAF2_1 193 196 PF00917 0.383
LIG_UBA3_1 128 133 PF00899 0.500
LIG_WRC_WIRS_1 147 152 PF05994 0.500
LIG_WRC_WIRS_1 172 177 PF05994 0.500
LIG_WW_3 43 47 PF00397 0.572
MOD_CDK_SPK_2 305 310 PF00069 0.500
MOD_CDK_SPxK_1 305 311 PF00069 0.500
MOD_CK1_1 141 147 PF00069 0.386
MOD_CK1_1 171 177 PF00069 0.383
MOD_CK1_1 232 238 PF00069 0.383
MOD_CK2_1 190 196 PF00069 0.383
MOD_CK2_1 3 9 PF00069 0.517
MOD_CK2_1 313 319 PF00069 0.404
MOD_GlcNHglycan 212 215 PF01048 0.424
MOD_GlcNHglycan 234 237 PF01048 0.383
MOD_GlcNHglycan 5 8 PF01048 0.614
MOD_GlcNHglycan 97 100 PF01048 0.609
MOD_GSK3_1 146 153 PF00069 0.500
MOD_GSK3_1 167 174 PF00069 0.383
MOD_GSK3_1 208 215 PF00069 0.475
MOD_GSK3_1 230 237 PF00069 0.383
MOD_N-GLC_1 141 146 PF02516 0.500
MOD_N-GLC_1 93 98 PF02516 0.611
MOD_N-GLC_2 111 113 PF02516 0.555
MOD_N-GLC_2 179 181 PF02516 0.383
MOD_NEK2_1 146 151 PF00069 0.344
MOD_NEK2_1 304 309 PF00069 0.500
MOD_NEK2_1 52 57 PF00069 0.588
MOD_NEK2_1 64 69 PF00069 0.383
MOD_NEK2_1 85 90 PF00069 0.565
MOD_NEK2_1 93 98 PF00069 0.471
MOD_NEK2_2 297 302 PF00069 0.383
MOD_PKA_1 285 291 PF00069 0.383
MOD_PKA_2 237 243 PF00069 0.383
MOD_PKA_2 285 291 PF00069 0.383
MOD_PKB_1 117 125 PF00069 0.644
MOD_Plk_1 122 128 PF00069 0.657
MOD_Plk_1 141 147 PF00069 0.150
MOD_Plk_1 297 303 PF00069 0.383
MOD_Plk_2-3 124 130 PF00069 0.624
MOD_Plk_4 111 117 PF00069 0.568
MOD_Plk_4 135 141 PF00069 0.500
MOD_Plk_4 168 174 PF00069 0.383
MOD_Plk_4 297 303 PF00069 0.383
MOD_Plk_4 52 58 PF00069 0.607
MOD_ProDKin_1 208 214 PF00069 0.500
MOD_ProDKin_1 230 236 PF00069 0.383
MOD_ProDKin_1 305 311 PF00069 0.500
MOD_SUMO_for_1 131 134 PF00179 0.391
MOD_SUMO_rev_2 55 65 PF00179 0.518
TRG_AP2beta_CARGO_1 49 58 PF09066 0.597
TRG_ER_diArg_1 116 119 PF00400 0.477
TRG_ER_diArg_1 220 222 PF00400 0.500
TRG_ER_diArg_1 284 286 PF00400 0.383
TRG_ER_diArg_1 336 339 PF00400 0.650

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4IPY9 Bodo saltans 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2026 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS