Putative kinetoplast DNA-associated protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast DNA-associated protein - putative

Species:

Leishmania infantum

UniProt:

A4IE05_LEIIN

TriTrypDb:

LINF_360069100

Length:

161

Annotations

Annotations by Jardim et al.

Kinetoplastid proteins, kinetoplast DNA-associated

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IE05

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IE05

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.371
CLV_NRD_NRD_1	51	53	PF00675	0.399
CLV_NRD_NRD_1	64	66	PF00675	0.453
CLV_NRD_NRD_1	73	75	PF00675	0.324
CLV_NRD_NRD_1	94	96	PF00675	0.374
CLV_PCSK_KEX2_1	145	147	PF00082	0.705
CLV_PCSK_KEX2_1	34	36	PF00082	0.386
CLV_PCSK_KEX2_1	51	53	PF00082	0.309
CLV_PCSK_KEX2_1	56	58	PF00082	0.376
CLV_PCSK_KEX2_1	66	68	PF00082	0.443
CLV_PCSK_KEX2_1	96	98	PF00082	0.386
CLV_PCSK_PC1ET2_1	145	147	PF00082	0.705
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.386
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.446
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.492
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.386
CLV_PCSK_PC7_1	52	58	PF00082	0.455
CLV_PCSK_SKI1_1	117	121	PF00082	0.529
CLV_PCSK_SKI1_1	125	129	PF00082	0.625
CLV_PCSK_SKI1_1	136	140	PF00082	0.614
CLV_PCSK_SKI1_1	142	146	PF00082	0.677
DEG_Nend_Nbox_1	1	3	PF02207	0.488
DOC_CYCLIN_yCln2_LP_2	107	113	PF00134	0.515
DOC_USP7_MATH_1	149	153	PF00917	0.582
DOC_USP7_MATH_1	154	158	PF00917	0.602
DOC_USP7_UBL2_3	131	135	PF12436	0.506
DOC_USP7_UBL2_3	136	140	PF12436	0.525
DOC_USP7_UBL2_3	151	155	PF12436	0.638
DOC_USP7_UBL2_3	156	160	PF12436	0.615
DOC_USP7_UBL2_3	37	41	PF12436	0.414
DOC_WW_Pin1_4	9	14	PF00397	0.381
LIG_14-3-3_CanoR_1	125	134	PF00244	0.394
LIG_14-3-3_CanoR_1	74	82	PF00244	0.518
LIG_14-3-3_CanoR_1	95	105	PF00244	0.439
LIG_LIR_Gen_1	12	19	PF02991	0.344
LIG_LIR_Gen_1	76	86	PF02991	0.398
LIG_LIR_Nem_3	12	17	PF02991	0.336
LIG_LIR_Nem_3	40	46	PF02991	0.387
LIG_LIR_Nem_3	76	81	PF02991	0.407
LIG_SH2_CRK	86	90	PF00017	0.329
LIG_UBA3_1	38	44	PF00899	0.374
LIG_WW_3	71	75	PF00397	0.504
MOD_CK1_1	12	18	PF00069	0.339
MOD_CK1_1	129	135	PF00069	0.582
MOD_CK1_1	99	105	PF00069	0.428
MOD_Cter_Amidation	158	161	PF01082	0.572
MOD_GlcNHglycan	128	131	PF01048	0.658
MOD_GlcNHglycan	150	154	PF01048	0.546
MOD_GlcNHglycan	156	159	PF01048	0.483
MOD_GlcNHglycan	98	101	PF01048	0.423
MOD_GSK3_1	125	132	PF00069	0.594
MOD_GSK3_1	136	143	PF00069	0.648
MOD_PIKK_1	44	50	PF00454	0.382
MOD_PIKK_1	99	105	PF00454	0.363
MOD_PKA_1	125	131	PF00069	0.521
MOD_PKA_1	96	102	PF00069	0.440
MOD_PKA_2	73	79	PF00069	0.491
MOD_PKA_2	96	102	PF00069	0.442
MOD_ProDKin_1	9	15	PF00069	0.380
MOD_SUMO_for_1	147	150	PF00179	0.476
TRG_DiLeu_BaEn_2	76	82	PF01217	0.455
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.497
TRG_ENDOCYTIC_2	43	46	PF00928	0.362
TRG_ENDOCYTIC_2	86	89	PF00928	0.332
TRG_ER_diArg_1	64	67	PF00400	0.542
TRG_ER_diArg_1	69	72	PF00400	0.500
TRG_ER_diArg_1	94	97	PF00400	0.380
TRG_NLS_Bipartite_1	135	149	PF00514	0.685
TRG_NLS_Bipartite_1	51	72	PF00514	0.500
TRG_NLS_MonoCore_2	64	69	PF00514	0.416
TRG_NLS_MonoExtC_3	144	150	PF00514	0.705
TRG_NLS_MonoExtC_3	64	69	PF00514	0.583
TRG_NLS_MonoExtN_4	142	149	PF00514	0.710
TRG_NLS_MonoExtN_4	62	69	PF00514	0.642
TRG_Pf-PMV_PEXEL_1	117	121	PF00026	0.436

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Y9	Leptomonas seymouri	72%	95%
A0A0N1IC67	Leptomonas seymouri	35%	100%
A0A0S4IRH7	Bodo saltans	34%	100%
A0A0S4J9G1	Bodo saltans	33%	100%
A0A0S4JC95	Bodo saltans	32%	100%
A0A0S4JL06	Bodo saltans	30%	100%
A0A1X0NLS3	Trypanosomatidae	39%	100%
A0A1X0NNA1	Trypanosomatidae	61%	90%
A0A1X0NNA5	Trypanosomatidae	39%	100%
A0A1X0NND5	Trypanosomatidae	36%	100%
A0A3Q8ILR8	Leishmania donovani	37%	100%
A0A3Q8IPT9	Leishmania donovani	100%	100%
A0A3R7MMA3	Trypanosoma rangeli	36%	100%
A0A3R7NF04	Trypanosoma rangeli	56%	86%
A0A422NSG2	Trypanosoma rangeli	35%	100%
A0A422NSJ6	Trypanosoma rangeli	36%	100%
A4HQA1	Leishmania braziliensis	31%	100%
A4HQA9	Leishmania braziliensis	87%	100%
A4IDZ7	Leishmania infantum	32%	100%
D0A3Z6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	77%
D0A408	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	87%
D0A410	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9AU19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AU27	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q07053	Crithidia fasciculata	38%	100%
Q4Q0G8	Leishmania major	93%	100%
Q4Q0H6	Leishmania major	32%	100%
V5BT80	Trypanosoma cruzi	58%	87%
V5DK57	Trypanosoma cruzi	34%	100%