Putative kinetoplast-associated protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast-associated protein - putative

Species:

Leishmania infantum

UniProt:

A4IDZ7_LEIIN

TriTrypDb:

LINF_360068300

Length:

124

Annotations

Annotations by Jardim et al.

Kinetoplastid proteins, kinetoplast-associated

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4IDZ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDZ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	7	9	PF00675	0.455
CLV_PCSK_KEX2_1	56	58	PF00082	0.381
CLV_PCSK_KEX2_1	7	9	PF00082	0.606
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.381
CLV_PCSK_PC7_1	3	9	PF00082	0.610
CLV_PCSK_SKI1_1	51	55	PF00082	0.450
DEG_Nend_Nbox_1	1	3	PF02207	0.474
DOC_ANK_TNKS_1	6	13	PF00023	0.560
DOC_CDC14_PxL_1	99	107	PF14671	0.471
DOC_USP7_MATH_1	60	64	PF00917	0.605
DOC_USP7_UBL2_3	109	113	PF12436	0.399
DOC_USP7_UBL2_3	22	26	PF12436	0.507
DOC_USP7_UBL2_3	37	41	PF12436	0.309
DOC_USP7_UBL2_3	70	74	PF12436	0.707
DOC_WW_Pin1_4	119	124	PF00397	0.437
LIG_14-3-3_CanoR_1	35	43	PF00244	0.462
LIG_14-3-3_CanoR_1	65	73	PF00244	0.492
LIG_FHA_1	37	43	PF00498	0.457
LIG_LIR_Gen_1	86	96	PF02991	0.374
LIG_LIR_Nem_3	40	46	PF02991	0.545
LIG_LIR_Nem_3	86	91	PF02991	0.385
LIG_PCNA_PIPBox_1	108	117	PF02747	0.549
LIG_SH2_CRK	43	47	PF00017	0.543
LIG_SH2_GRB2like	88	91	PF00017	0.318
LIG_SH2_STAP1	14	18	PF00017	0.505
LIG_SH2_STAP1	88	92	PF00017	0.364
LIG_UBA3_1	16	22	PF00899	0.444
MOD_CDK_SPK_2	119	124	PF00069	0.457
MOD_CK1_1	68	74	PF00069	0.564
MOD_GlcNHglycan	46	49	PF01048	0.500
MOD_GlcNHglycan	85	88	PF01048	0.571
MOD_GSK3_1	42	49	PF00069	0.447
MOD_GSK3_1	79	86	PF00069	0.632
MOD_NEK2_1	42	47	PF00069	0.462
MOD_NEK2_2	12	17	PF00069	0.497
MOD_NEK2_2	60	65	PF00069	0.616
MOD_PIKK_1	65	71	PF00454	0.606
MOD_PK_1	28	34	PF00069	0.472
MOD_PKA_2	79	85	PF00069	0.572
MOD_Plk_4	12	18	PF00069	0.503
MOD_SUMO_for_1	73	76	PF00179	0.637
TRG_ENDOCYTIC_2	14	17	PF00928	0.498
TRG_ENDOCYTIC_2	43	46	PF00928	0.546
TRG_ENDOCYTIC_2	88	91	PF00928	0.371
TRG_ER_diArg_1	6	8	PF00400	0.613

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Y9	Leptomonas seymouri	33%	73%
A0A0N1IC67	Leptomonas seymouri	69%	98%
A0A0S4IRH7	Bodo saltans	34%	100%
A0A0S4J5T0	Bodo saltans	31%	89%
A0A0S4J9G1	Bodo saltans	35%	100%
A0A0S4JC95	Bodo saltans	43%	100%
A0A0S4JL06	Bodo saltans	32%	100%
A0A0S4JT41	Bodo saltans	47%	100%
A0A1X0NLS3	Trypanosomatidae	56%	100%
A0A1X0NNA1	Trypanosomatidae	30%	70%
A0A1X0NNA5	Trypanosomatidae	57%	100%
A0A1X0NND5	Trypanosomatidae	57%	96%
A0A3Q8ILR8	Leishmania donovani	99%	100%
A0A3Q8IPT9	Leishmania donovani	32%	77%
A0A3R7KKP8	Trypanosoma rangeli	53%	100%
A0A3R7MMA3	Trypanosoma rangeli	56%	92%
A0A3R7NF04	Trypanosoma rangeli	32%	66%
A0A422NSG2	Trypanosoma rangeli	54%	95%
A0A422NSJ6	Trypanosoma rangeli	55%	100%
A4HQA1	Leishmania braziliensis	82%	100%
A4HQA9	Leishmania braziliensis	35%	100%
A4IE05	Leishmania infantum	32%	77%
D0A408	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	67%
D0A410	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	98%
E9AU19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9AU27	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
Q07053	Crithidia fasciculata	70%	97%
Q4Q0G8	Leishmania major	37%	100%
Q4Q0H6	Leishmania major	95%	100%
V5BT80	Trypanosoma cruzi	33%	67%
V5DK57	Trypanosoma cruzi	56%	97%