Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Phosphorylated CTD interacting factor 1 WW domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4IDW7_LEIIN

TriTrypDb:

LINF_360065000

Length:

657

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDW7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDW7

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0000993	RNA polymerase II complex binding	5	8
GO:0001098	basal transcription machinery binding	3	8
GO:0001099	basal RNA polymerase II transcription machinery binding	4	8
GO:0003824	catalytic activity	1	8
GO:0005488	binding	1	8
GO:0005515	protein binding	2	8
GO:0008168	methyltransferase activity	4	8
GO:0008173	RNA methyltransferase activity	4	8
GO:0008174	mRNA methyltransferase activity	5	8
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	5	8

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	195	197	PF00675	0.433
CLV_NRD_NRD_1	213	215	PF00675	0.462
CLV_NRD_NRD_1	587	589	PF00675	0.643
CLV_NRD_NRD_1	82	84	PF00675	0.472
CLV_PCSK_KEX2_1	195	197	PF00082	0.418
CLV_PCSK_KEX2_1	589	591	PF00082	0.630
CLV_PCSK_KEX2_1	82	84	PF00082	0.472
CLV_PCSK_PC1ET2_1	195	197	PF00082	0.418
CLV_PCSK_PC1ET2_1	589	591	PF00082	0.637
CLV_PCSK_SKI1_1	12	16	PF00082	0.417

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P0J4	Trypanosomatidae	31%	100%
A0A3Q8IGM5	Leishmania donovani	100%	100%
A0A422NKA3	Trypanosoma rangeli	33%	100%
A4HQ69	Leishmania braziliensis	78%	100%
E9ATY8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q0K8	Leishmania major	92%	100%

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