Arylamine N-acetyltransferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDR4_LEIIN

TriTrypDb:

LINF_360058100

Length:

235

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 7
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDR4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDR4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	159	161	PF00675	0.503
CLV_NRD_NRD_1	51	53	PF00675	0.471
CLV_NRD_NRD_1	86	88	PF00675	0.478
CLV_PCSK_SKI1_1	155	159	PF00082	0.395
CLV_PCSK_SKI1_1	88	92	PF00082	0.533
CLV_Separin_Metazoa	77	81	PF03568	0.461
DEG_SPOP_SBC_1	21	25	PF00917	0.482
DOC_MAPK_DCC_7	115	124	PF00069	0.477
DOC_MAPK_gen_1	115	124	PF00069	0.477
DOC_MAPK_MEF2A_6	115	124	PF00069	0.477
DOC_PP2B_PxIxI_1	119	125	PF00149	0.351
DOC_USP7_MATH_1	163	167	PF00917	0.523
DOC_USP7_MATH_1	21	25	PF00917	0.482
DOC_WW_Pin1_4	124	129	PF00397	0.478
DOC_WW_Pin1_4	167	172	PF00397	0.394
DOC_WW_Pin1_4	184	189	PF00397	0.369
LIG_14-3-3_CanoR_1	217	226	PF00244	0.526
LIG_BIR_II_1	1	5	PF00653	0.408
LIG_BRCT_BRCA1_1	11	15	PF00533	0.314
LIG_CaM_IQ_9	60	75	PF13499	0.433
LIG_deltaCOP1_diTrp_1	172	177	PF00928	0.473
LIG_deltaCOP1_diTrp_1	81	86	PF00928	0.421
LIG_FHA_1	185	191	PF00498	0.422
LIG_FHA_2	108	114	PF00498	0.490
LIG_FHA_2	167	173	PF00498	0.487
LIG_LIR_Gen_1	12	22	PF02991	0.446
LIG_LIR_Gen_1	228	234	PF02991	0.449
LIG_LIR_Gen_1	81	91	PF02991	0.386
LIG_LIR_LC3C_4	215	220	PF02991	0.352
LIG_LIR_Nem_3	12	18	PF02991	0.443
LIG_LIR_Nem_3	228	233	PF02991	0.383
LIG_LIR_Nem_3	81	86	PF02991	0.464
LIG_Pex14_1	173	177	PF04695	0.349
LIG_Pex14_2	158	162	PF04695	0.401
LIG_Pex14_2	226	230	PF04695	0.386
LIG_SH2_STAT5	186	189	PF00017	0.391
LIG_SH3_3	114	120	PF00018	0.454
LIG_SH3_3	15	21	PF00018	0.455
LIG_SUMO_SIM_par_1	27	34	PF11976	0.576
LIG_SxIP_EBH_1	204	214	PF03271	0.394
LIG_TRFH_1	42	46	PF08558	0.415
LIG_UBA3_1	174	180	PF00899	0.457
LIG_WRC_WIRS_1	174	179	PF05994	0.475
MOD_CK1_1	166	172	PF00069	0.410
MOD_CK1_1	176	182	PF00069	0.463
MOD_CK1_1	93	99	PF00069	0.473
MOD_CK2_1	166	172	PF00069	0.480
MOD_CK2_1	225	231	PF00069	0.326
MOD_Cter_Amidation	50	53	PF01082	0.427
MOD_GlcNHglycan	155	158	PF01048	0.522
MOD_GSK3_1	120	127	PF00069	0.442
MOD_GSK3_1	163	170	PF00069	0.471
MOD_GSK3_1	184	191	PF00069	0.344
MOD_GSK3_1	93	100	PF00069	0.537
MOD_N-GLC_1	120	125	PF02516	0.427
MOD_N-GLC_1	166	171	PF02516	0.513
MOD_N-GLC_1	184	189	PF02516	0.473
MOD_N-GLC_2	225	227	PF02516	0.315
MOD_N-GLC_2	7	9	PF02516	0.290
MOD_NEK2_1	10	15	PF00069	0.426
MOD_NEK2_1	133	138	PF00069	0.405
MOD_NEK2_1	218	223	PF00069	0.419
MOD_NEK2_1	22	27	PF00069	0.361
MOD_NEK2_1	97	102	PF00069	0.401
MOD_PKA_2	79	85	PF00069	0.416
MOD_Plk_1	120	126	PF00069	0.442
MOD_Plk_1	35	41	PF00069	0.450
MOD_Plk_4	133	139	PF00069	0.430
MOD_Plk_4	173	179	PF00069	0.454
MOD_Plk_4	58	64	PF00069	0.416
MOD_Plk_4	79	85	PF00069	0.483
MOD_Plk_4	93	99	PF00069	0.421
MOD_ProDKin_1	124	130	PF00069	0.472
MOD_ProDKin_1	167	173	PF00069	0.393
MOD_ProDKin_1	184	190	PF00069	0.365
TRG_Pf-PMV_PEXEL_1	139	143	PF00026	0.434

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB92	Leptomonas seymouri	71%	100%
A0A1X0P0Q7	Trypanosomatidae	48%	100%
A0A3Q8IPJ6	Leishmania donovani	100%	100%
A0A3R7NWI3	Trypanosoma rangeli	46%	91%
A4HQ03	Leishmania braziliensis	92%	100%
E9ATS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4Q0S7	Leishmania major	97%	100%
V5BQ42	Trypanosoma cruzi	46%	100%