Leucine Rich repeat family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Leucine Rich repeat - putative

Species:

Leishmania infantum

UniProt:

A4IDR2_LEIIN

TriTrypDb:

LINF_360057900

Length:

1208

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	10
GO:0042995	cell projection	2	10
GO:0043226	organelle	2	10
GO:0043227	membrane-bounded organelle	3	10
GO:0110165	cellular anatomical entity	1	10
GO:0120025	plasma membrane bounded cell projection	3	10

Previous1Next

Expansion

Sequence features

A4IDR2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDR2

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006950	response to stress	2	6
GO:0006952	defense response	3	6
GO:0050896	response to stimulus	1	6

Previous1Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1001	1005	PF00656	0.331
CLV_C14_Caspase3-7	1048	1052	PF00656	0.445
CLV_C14_Caspase3-7	1143	1147	PF00656	0.407
CLV_C14_Caspase3-7	193	197	PF00656	0.576
CLV_C14_Caspase3-7	367	371	PF00656	0.599
CLV_C14_Caspase3-7	731	735	PF00656	0.379
CLV_NRD_NRD_1	1084	1086	PF00675	0.478
CLV_NRD_NRD_1	357	359	PF00675	0.643
CLV_NRD_NRD_1	394	396	PF00675	0.805
CLV_NRD_NRD_1	475	477	PF00675	0.470

Previous1 2 3 4 5…43Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P813	Leptomonas seymouri	57%	99%
A0A3S5ISR4	Trypanosoma rangeli	29%	100%
A0A3S7XBN2	Leishmania donovani	99%	100%
A4HQ01	Leishmania braziliensis	75%	100%
D0A4F4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9ATR8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q0S9	Leishmania major	93%	100%
V5BKI3	Trypanosoma cruzi	28%	100%

Previous1Next