Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PPR repeat/Pentatricopeptide repeat domain/PPR repeat family - putative

Species:

Leishmania infantum

UniProt:

A4IDQ9_LEIIN

TriTrypDb:

LINF_360057600

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDQ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDQ9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	240	244	PF00656	0.439
CLV_NRD_NRD_1	166	168	PF00675	0.323
CLV_NRD_NRD_1	47	49	PF00675	0.466
CLV_PCSK_KEX2_1	166	168	PF00082	0.323
CLV_PCSK_KEX2_1	47	49	PF00082	0.454
CLV_PCSK_SKI1_1	121	125	PF00082	0.341
CLV_PCSK_SKI1_1	15	19	PF00082	0.307
CLV_PCSK_SKI1_1	209	213	PF00082	0.376
CLV_PCSK_SKI1_1	230	234	PF00082	0.389
CLV_PCSK_SKI1_1	48	52	PF00082	0.427
CLV_PCSK_SKI1_1	74	78	PF00082	0.427
CLV_Separin_Metazoa	231	235	PF03568	0.473
DEG_APCC_DBOX_1	229	237	PF00400	0.453
DOC_ANK_TNKS_1	216	223	PF00023	0.427
DOC_CKS1_1	170	175	PF01111	0.504
DOC_CYCLIN_RxL_1	227	235	PF00134	0.439
DOC_MAPK_gen_1	206	214	PF00069	0.376
DOC_MAPK_gen_1	99	107	PF00069	0.388
DOC_MAPK_MEF2A_6	99	107	PF00069	0.325
DOC_MAPK_NFAT4_5	100	108	PF00069	0.416
DOC_PP4_FxxP_1	150	153	PF00568	0.427
DOC_WW_Pin1_4	169	174	PF00397	0.507
LIG_14-3-3_CanoR_1	11	17	PF00244	0.438
LIG_14-3-3_CanoR_1	181	185	PF00244	0.586
LIG_14-3-3_CanoR_1	217	225	PF00244	0.240
LIG_14-3-3_CanoR_1	238	243	PF00244	0.535
LIG_14-3-3_CanoR_1	252	261	PF00244	0.592
LIG_APCC_ABBA_1	105	110	PF00400	0.427
LIG_BIR_II_1	1	5	PF00653	0.509
LIG_DLG_GKlike_1	238	245	PF00625	0.560
LIG_eIF4E_1	86	92	PF01652	0.323
LIG_FHA_1	122	128	PF00498	0.323
LIG_FHA_1	16	22	PF00498	0.301
LIG_FHA_1	170	176	PF00498	0.481
LIG_FHA_1	227	233	PF00498	0.392
LIG_FHA_1	248	254	PF00498	0.469
LIG_FHA_1	52	58	PF00498	0.307
LIG_FHA_1	87	93	PF00498	0.317
LIG_FHA_2	238	244	PF00498	0.469
LIG_GBD_Chelix_1	103	111	PF00786	0.427
LIG_LIR_Apic_2	147	153	PF02991	0.427
LIG_LIR_Gen_1	192	203	PF02991	0.312
LIG_LIR_Gen_1	87	96	PF02991	0.362
LIG_LIR_Nem_3	192	198	PF02991	0.312
LIG_LIR_Nem_3	221	226	PF02991	0.299
LIG_LIR_Nem_3	255	261	PF02991	0.673
LIG_LIR_Nem_3	87	91	PF02991	0.304
LIG_Pex14_2	12	16	PF04695	0.535
LIG_SH2_CRK	195	199	PF00017	0.307
LIG_SH2_CRK	53	57	PF00017	0.307
LIG_SH2_CRK	88	92	PF00017	0.323
LIG_SH2_SRC	223	226	PF00017	0.392
LIG_SH2_STAP1	158	162	PF00017	0.308
LIG_SH2_STAP1	228	232	PF00017	0.398
LIG_SH2_STAP1	53	57	PF00017	0.307
LIG_SH2_STAP1	88	92	PF00017	0.330
LIG_SH2_STAT5	158	161	PF00017	0.308
LIG_SH2_STAT5	228	231	PF00017	0.410
LIG_SH2_STAT5	261	264	PF00017	0.657
LIG_SH2_STAT5	53	56	PF00017	0.307
LIG_SH2_STAT5	86	89	PF00017	0.307
LIG_SH3_3	111	117	PF00018	0.357
LIG_SH3_3	167	173	PF00018	0.406
LIG_SUMO_SIM_par_1	124	131	PF11976	0.454
LIG_TRAF2_1	273	276	PF00917	0.598
LIG_TYR_ITIM	193	198	PF00017	0.307
LIG_WRC_WIRS_1	21	26	PF05994	0.402
MOD_CK1_1	128	134	PF00069	0.454
MOD_CK2_1	253	259	PF00069	0.583
MOD_GlcNHglycan	26	29	PF01048	0.378
MOD_GlcNHglycan	4	7	PF01048	0.530
MOD_GSK3_1	11	18	PF00069	0.415
MOD_GSK3_1	121	128	PF00069	0.392
MOD_GSK3_1	20	27	PF00069	0.315
MOD_GSK3_1	262	269	PF00069	0.571
MOD_GSK3_1	51	58	PF00069	0.358
MOD_N-GLC_1	247	252	PF02516	0.578
MOD_N-GLC_2	93	95	PF02516	0.364
MOD_NEK2_1	156	161	PF00069	0.323
MOD_NEK2_1	237	242	PF00069	0.417
MOD_NEK2_1	24	29	PF00069	0.410
MOD_NEK2_1	40	45	PF00069	0.285
MOD_NEK2_1	51	56	PF00069	0.256
MOD_PIKK_1	183	189	PF00454	0.584
MOD_PKA_2	10	16	PF00069	0.492
MOD_PKA_2	180	186	PF00069	0.569
MOD_PKA_2	216	222	PF00069	0.240
MOD_PKA_2	237	243	PF00069	0.525
MOD_Plk_1	191	197	PF00069	0.323
MOD_Plk_1	247	253	PF00069	0.585
MOD_Plk_4	194	200	PF00069	0.323
MOD_Plk_4	41	47	PF00069	0.327
MOD_Plk_4	52	58	PF00069	0.261
MOD_Plk_4	87	93	PF00069	0.405
MOD_ProDKin_1	169	175	PF00069	0.505
TRG_ENDOCYTIC_2	195	198	PF00928	0.307
TRG_ENDOCYTIC_2	215	218	PF00928	0.313
TRG_ENDOCYTIC_2	223	226	PF00928	0.298
TRG_ENDOCYTIC_2	53	56	PF00928	0.307
TRG_ENDOCYTIC_2	88	91	PF00928	0.323
TRG_ER_diArg_1	46	48	PF00400	0.454
TRG_NES_CRM1_1	102	115	PF08389	0.427
TRG_Pf-PMV_PEXEL_1	15	19	PF00026	0.307
TRG_Pf-PMV_PEXEL_1	230	235	PF00026	0.500

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1J7	Leptomonas seymouri	81%	100%
A0A0S4IYI9	Bodo saltans	47%	100%
A0A1X0P0D8	Trypanosomatidae	60%	88%
A0A3Q8IF22	Leishmania donovani	25%	100%
A0A3Q8IJ22	Leishmania donovani	99%	100%
A0A3R7KPI7	Trypanosoma rangeli	57%	99%
A4HPZ8	Leishmania braziliensis	90%	100%
A4I129	Leishmania infantum	25%	100%
C9ZW80	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	100%
D0A4F1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	71%
E9ATR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9AX66	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
Q4Q0T2	Leishmania major	95%	100%
Q4QAB0	Leishmania major	23%	100%
Q5BIV3	Arabidopsis thaliana	24%	76%
Q940Z1	Arabidopsis thaliana	25%	88%
Q9FFZ2	Arabidopsis thaliana	22%	84%
Q9LG23	Arabidopsis thaliana	22%	70%
Q9SAB4	Arabidopsis thaliana	22%	69%
V5DLI8	Trypanosoma cruzi	58%	91%