PABS domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDQ8_LEIIN

TriTrypDb:

LINF_360057500

Length:

511

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDQ8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.643
CLV_NRD_NRD_1	10	12	PF00675	0.556
CLV_NRD_NRD_1	101	103	PF00675	0.621
CLV_NRD_NRD_1	211	213	PF00675	0.417
CLV_NRD_NRD_1	23	25	PF00675	0.635
CLV_PCSK_FUR_1	7	11	PF00082	0.539
CLV_PCSK_KEX2_1	10	12	PF00082	0.561
CLV_PCSK_KEX2_1	162	164	PF00082	0.513
CLV_PCSK_KEX2_1	21	23	PF00082	0.639
CLV_PCSK_KEX2_1	31	33	PF00082	0.442
CLV_PCSK_KEX2_1	7	9	PF00082	0.603
CLV_PCSK_KEX2_1	78	80	PF00082	0.395
CLV_PCSK_PC1ET2_1	162	164	PF00082	0.513
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.627
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.424
CLV_PCSK_PC1ET2_1	78	80	PF00082	0.395
CLV_PCSK_PC7_1	18	24	PF00082	0.585
CLV_PCSK_SKI1_1	323	327	PF00082	0.398
CLV_PCSK_SKI1_1	403	407	PF00082	0.488
CLV_PCSK_SKI1_1	75	79	PF00082	0.414
DEG_COP1_1	54	61	PF00400	0.364
DEG_ODPH_VHL_1	4	17	PF01847	0.573
DEG_SPOP_SBC_1	268	272	PF00917	0.627
DOC_MAPK_DCC_7	298	308	PF00069	0.287
DOC_MAPK_gen_1	7	17	PF00069	0.526
DOC_MAPK_JIP1_4	407	413	PF00069	0.430
DOC_MAPK_MEF2A_6	46	53	PF00069	0.457
DOC_MAPK_NFAT4_5	46	54	PF00069	0.465
DOC_USP7_MATH_1	109	113	PF00917	0.725
DOC_USP7_MATH_1	238	242	PF00917	0.563
DOC_WW_Pin1_4	131	136	PF00397	0.618
DOC_WW_Pin1_4	212	217	PF00397	0.364
LIG_14-3-3_CanoR_1	110	114	PF00244	0.644
LIG_14-3-3_CanoR_1	129	136	PF00244	0.492
LIG_14-3-3_CanoR_1	245	254	PF00244	0.695
LIG_14-3-3_CanoR_1	276	280	PF00244	0.506
LIG_14-3-3_CanoR_1	443	451	PF00244	0.469
LIG_14-3-3_CanoR_1	52	59	PF00244	0.392
LIG_14-3-3_CanoR_1	64	72	PF00244	0.357
LIG_14-3-3_CanoR_1	8	17	PF00244	0.524
LIG_14-3-3_CanoR_1	86	90	PF00244	0.429
LIG_14-3-3_CterR_2	507	511	PF00244	0.367
LIG_Actin_WH2_2	190	206	PF00022	0.344
LIG_Actin_WH2_2	76	94	PF00022	0.377
LIG_FHA_1	10	16	PF00498	0.489
LIG_FHA_1	303	309	PF00498	0.446
LIG_FHA_1	400	406	PF00498	0.462
LIG_FHA_1	53	59	PF00498	0.546
LIG_FHA_1	64	70	PF00498	0.300
LIG_FHA_1	86	92	PF00498	0.468
LIG_FHA_2	137	143	PF00498	0.655
LIG_FHA_2	226	232	PF00498	0.555
LIG_FHA_2	348	354	PF00498	0.419
LIG_FHA_2	373	379	PF00498	0.408
LIG_FHA_2	468	474	PF00498	0.431
LIG_FHA_2	96	102	PF00498	0.666
LIG_GBD_Chelix_1	474	482	PF00786	0.371
LIG_LIR_Apic_2	112	116	PF02991	0.655
LIG_LIR_Gen_1	194	203	PF02991	0.331
LIG_LIR_Gen_1	375	385	PF02991	0.349
LIG_LIR_Nem_3	194	198	PF02991	0.331
LIG_LIR_Nem_3	375	380	PF02991	0.348
LIG_LIR_Nem_3	473	479	PF02991	0.420
LIG_MYND_1	2	6	PF01753	0.650
LIG_Pex14_2	44	48	PF04695	0.435
LIG_SH2_CRK	200	204	PF00017	0.413
LIG_SH2_CRK	377	381	PF00017	0.326
LIG_SH2_CRK	428	432	PF00017	0.442
LIG_SH2_NCK_1	428	432	PF00017	0.442
LIG_SH2_SRC	230	233	PF00017	0.390
LIG_SH2_STAP1	377	381	PF00017	0.326
LIG_SH2_STAP1	428	432	PF00017	0.442
LIG_SH2_STAP1	463	467	PF00017	0.381
LIG_SH2_STAP1	479	483	PF00017	0.343
LIG_SH2_STAT5	148	151	PF00017	0.364
LIG_SH2_STAT5	200	203	PF00017	0.408
LIG_SH3_1	103	109	PF00018	0.603
LIG_SH3_2	3	8	PF14604	0.635
LIG_SH3_3	103	109	PF00018	0.563
LIG_SH3_3	91	97	PF00018	0.503
LIG_SUMO_SIM_par_1	329	336	PF11976	0.351
LIG_TRAF2_1	98	101	PF00917	0.621
LIG_TYR_ITIM	198	203	PF00017	0.408
LIG_TYR_ITSM	373	380	PF00017	0.355
LIG_WRC_WIRS_1	192	197	PF05994	0.332
LIG_WW_3	107	111	PF00397	0.686
MOD_CK1_1	167	173	PF00069	0.440
MOD_CK1_1	191	197	PF00069	0.468
MOD_CK1_1	233	239	PF00069	0.726
MOD_CK2_1	284	290	PF00069	0.487
MOD_CK2_1	95	101	PF00069	0.656
MOD_GlcNHglycan	136	139	PF01048	0.609
MOD_GlcNHglycan	25	28	PF01048	0.380
MOD_GlcNHglycan	250	253	PF01048	0.760
MOD_GlcNHglycan	420	423	PF01048	0.396
MOD_GSK3_1	232	239	PF00069	0.691
MOD_GSK3_1	347	354	PF00069	0.495
MOD_GSK3_1	457	464	PF00069	0.397
MOD_N-GLC_1	246	251	PF02516	0.606
MOD_N-GLC_1	465	470	PF02516	0.322
MOD_NEK2_1	17	22	PF00069	0.610
MOD_NEK2_1	38	43	PF00069	0.371
MOD_NEK2_1	388	393	PF00069	0.362
MOD_NEK2_1	465	470	PF00069	0.359
MOD_NEK2_1	51	56	PF00069	0.412
MOD_PIKK_1	240	246	PF00454	0.560
MOD_PIKK_1	269	275	PF00454	0.654
MOD_PIKK_1	63	69	PF00454	0.420
MOD_PKA_1	23	29	PF00069	0.551
MOD_PKA_1	9	15	PF00069	0.508
MOD_PKA_2	109	115	PF00069	0.686
MOD_PKA_2	128	134	PF00069	0.492
MOD_PKA_2	164	170	PF00069	0.494
MOD_PKA_2	17	23	PF00069	0.534
MOD_PKA_2	275	281	PF00069	0.523
MOD_PKA_2	51	57	PF00069	0.509
MOD_PKA_2	63	69	PF00069	0.374
MOD_PKA_2	85	91	PF00069	0.422
MOD_PKA_2	9	15	PF00069	0.504
MOD_PKB_1	7	15	PF00069	0.538
MOD_Plk_1	167	173	PF00069	0.440
MOD_Plk_1	38	44	PF00069	0.375
MOD_Plk_4	172	178	PF00069	0.391
MOD_Plk_4	188	194	PF00069	0.352
MOD_Plk_4	445	451	PF00069	0.371
MOD_Plk_4	478	484	PF00069	0.422
MOD_Plk_4	488	494	PF00069	0.429
MOD_ProDKin_1	131	137	PF00069	0.619
MOD_ProDKin_1	212	218	PF00069	0.364
MOD_SUMO_rev_2	13	17	PF00179	0.564
MOD_SUMO_rev_2	278	288	PF00179	0.504
MOD_SUMO_rev_2	353	358	PF00179	0.516
TRG_ENDOCYTIC_2	200	203	PF00928	0.408
TRG_ENDOCYTIC_2	377	380	PF00928	0.326
TRG_ENDOCYTIC_2	381	384	PF00928	0.340
TRG_ENDOCYTIC_2	428	431	PF00928	0.373
TRG_ENDOCYTIC_2	479	482	PF00928	0.345
TRG_ER_diArg_1	22	24	PF00400	0.647
TRG_ER_diArg_1	504	507	PF00400	0.368
TRG_ER_diArg_1	6	9	PF00400	0.599
TRG_NLS_Bipartite_1	7	25	PF00514	0.520
TRG_NLS_MonoCore_2	20	25	PF00514	0.574
TRG_NLS_MonoExtN_4	18	25	PF00514	0.533

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDJ0	Leptomonas seymouri	54%	100%
A0A3S7XBN4	Leishmania donovani	100%	100%
A4HPZ7	Leishmania braziliensis	77%	100%
E9ATR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q0T3	Leishmania major	92%	100%