LeishMANIAdb
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Paraflagellar_rod_protein_-_putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Paraflagellar_rod_protein_-_putative
Gene product:
paraflagellar rod component - putative
Species:
Leishmania infantum
UniProt:
A4IDQ6_LEIIN
TriTrypDb:
LINF_360057300
Length:
317

Annotations

Annotations by Jardim et al.

Flagella, paraflagellar rod component Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005929 cilium 4 1
GO:0031514 motile cilium 5 1
GO:0042995 cell projection 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0110165 cellular anatomical entity 1 1
GO:0120025 plasma membrane bounded cell projection 3 1

Expansion

Sequence features

A4IDQ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDQ6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 46 50 PF00656 0.415
CLV_C14_Caspase3-7 79 83 PF00656 0.500
CLV_NRD_NRD_1 147 149 PF00675 0.387
CLV_NRD_NRD_1 288 290 PF00675 0.521
CLV_PCSK_KEX2_1 146 148 PF00082 0.457
CLV_PCSK_KEX2_1 159 161 PF00082 0.474
CLV_PCSK_KEX2_1 288 290 PF00082 0.468
CLV_PCSK_PC1ET2_1 146 148 PF00082 0.464
CLV_PCSK_PC1ET2_1 159 161 PF00082 0.462
CLV_PCSK_SKI1_1 124 128 PF00082 0.373
CLV_PCSK_SKI1_1 182 186 PF00082 0.480
CLV_PCSK_SKI1_1 209 213 PF00082 0.486
CLV_PCSK_SKI1_1 26 30 PF00082 0.369
CLV_PCSK_SKI1_1 264 268 PF00082 0.485
CLV_PCSK_SKI1_1 307 311 PF00082 0.544
DEG_APCC_DBOX_1 135 143 PF00400 0.424
DEG_Nend_UBRbox_2 1 3 PF02207 0.595
DOC_CKS1_1 39 44 PF01111 0.474
DOC_MAPK_DCC_7 209 218 PF00069 0.440
DOC_MAPK_gen_1 179 188 PF00069 0.474
DOC_MAPK_gen_1 238 246 PF00069 0.519
DOC_MAPK_gen_1 304 311 PF00069 0.662
DOC_MAPK_MEF2A_6 209 218 PF00069 0.440
DOC_USP7_MATH_1 112 116 PF00917 0.414
DOC_USP7_MATH_1 134 138 PF00917 0.457
DOC_USP7_MATH_1 30 34 PF00917 0.423
DOC_WW_Pin1_4 130 135 PF00397 0.420
DOC_WW_Pin1_4 173 178 PF00397 0.353
DOC_WW_Pin1_4 38 43 PF00397 0.474
LIG_14-3-3_CanoR_1 182 187 PF00244 0.445
LIG_14-3-3_CanoR_1 209 214 PF00244 0.486
LIG_BIR_III_2 231 235 PF00653 0.423
LIG_BIR_III_4 242 246 PF00653 0.598
LIG_BRCT_BRCA1_1 136 140 PF00533 0.438
LIG_Clathr_ClatBox_1 139 143 PF01394 0.325
LIG_FHA_1 121 127 PF00498 0.390
LIG_FHA_1 183 189 PF00498 0.474
LIG_FHA_1 213 219 PF00498 0.476
LIG_FHA_1 246 252 PF00498 0.557
LIG_FHA_1 294 300 PF00498 0.522
LIG_FHA_1 39 45 PF00498 0.477
LIG_FHA_2 185 191 PF00498 0.369
LIG_FHA_2 256 262 PF00498 0.469
LIG_Integrin_RGD_1 160 162 PF01839 0.474
LIG_LIR_Nem_3 190 196 PF02991 0.509
LIG_PDZ_Class_2 312 317 PF00595 0.723
LIG_SH2_NCK_1 225 229 PF00017 0.384
LIG_SH2_STAP1 171 175 PF00017 0.500
LIG_SH2_STAP1 225 229 PF00017 0.500
LIG_SH2_STAT5 225 228 PF00017 0.500
LIG_SH2_STAT5 43 46 PF00017 0.388
LIG_SH3_3 208 214 PF00018 0.410
LIG_SH3_3 3 9 PF00018 0.527
LIG_SUMO_SIM_anti_2 308 313 PF11976 0.593
LIG_SUMO_SIM_par_1 184 190 PF11976 0.474
LIG_SUMO_SIM_par_1 27 33 PF11976 0.474
LIG_SUMO_SIM_par_1 296 303 PF11976 0.606
LIG_TRAF2_1 187 190 PF00917 0.353
LIG_TRAF2_1 300 303 PF00917 0.598
MOD_CDC14_SPxK_1 133 136 PF00782 0.384
MOD_CDK_SPxK_1 130 136 PF00069 0.384
MOD_CDK_SPxK_1 173 179 PF00069 0.353
MOD_CK1_1 200 206 PF00069 0.477
MOD_CK1_1 70 76 PF00069 0.423
MOD_CK2_1 184 190 PF00069 0.353
MOD_CK2_1 256 262 PF00069 0.465
MOD_CK2_1 30 36 PF00069 0.500
MOD_CK2_1 90 96 PF00069 0.345
MOD_GlcNHglycan 101 104 PF01048 0.460
MOD_GlcNHglycan 114 117 PF01048 0.391
MOD_GlcNHglycan 69 72 PF01048 0.434
MOD_GSK3_1 130 137 PF00069 0.432
MOD_GSK3_1 138 145 PF00069 0.362
MOD_GSK3_1 178 185 PF00069 0.423
MOD_GSK3_1 200 207 PF00069 0.413
MOD_GSK3_1 217 224 PF00069 0.500
MOD_GSK3_1 251 258 PF00069 0.556
MOD_N-GLC_1 182 187 PF02516 0.500
MOD_NEK2_1 13 18 PF00069 0.538
MOD_NEK2_1 20 25 PF00069 0.510
MOD_NEK2_1 62 67 PF00069 0.474
MOD_NEK2_1 99 104 PF00069 0.354
MOD_NEK2_2 204 209 PF00069 0.485
MOD_PIKK_1 30 36 PF00454 0.474
MOD_PK_1 138 144 PF00069 0.423
MOD_PKA_2 178 184 PF00069 0.462
MOD_Plk_1 162 168 PF00069 0.433
MOD_Plk_1 182 188 PF00069 0.205
MOD_Plk_1 221 227 PF00069 0.442
MOD_Plk_1 307 313 PF00069 0.528
MOD_Plk_1 53 59 PF00069 0.415
MOD_Plk_1 90 96 PF00069 0.399
MOD_Plk_4 14 20 PF00069 0.504
MOD_Plk_4 212 218 PF00069 0.466
MOD_Plk_4 251 257 PF00069 0.475
MOD_Plk_4 294 300 PF00069 0.671
MOD_Plk_4 307 313 PF00069 0.489
MOD_ProDKin_1 130 136 PF00069 0.420
MOD_ProDKin_1 173 179 PF00069 0.353
MOD_ProDKin_1 38 44 PF00069 0.474
MOD_SUMO_for_1 51 54 PF00179 0.423
TRG_ER_diArg_1 147 149 PF00400 0.423
TRG_Pf-PMV_PEXEL_1 124 128 PF00026 0.423
TRG_Pf-PMV_PEXEL_1 153 158 PF00026 0.462

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PFN3 Leptomonas seymouri 55% 100%
A0A0S4KFB4 Bodo saltans 36% 100%
A0A1X0P0E6 Trypanosomatidae 38% 97%
A0A3Q8IHR7 Leishmania donovani 100% 100%
A0A3R7MXS0 Trypanosoma rangeli 34% 98%
A4HPZ5 Leishmania braziliensis 71% 100%
D0A4E9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 96%
E9ATR2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
Q4Q0T5 Leishmania major 95% 100%
V5BUR3 Trypanosoma cruzi 36% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS