LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IDP1_LEIIN
TriTrypDb:
LINF_360055600
Length:
1240

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005759 mitochondrial matrix 5 1
GO:0031974 membrane-enclosed lumen 2 1
GO:0035770 ribonucleoprotein granule 3 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0043233 organelle lumen 3 1
GO:0070013 intracellular organelle lumen 4 1
GO:0099080 supramolecular complex 2 1
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Expansion

Sequence features

A4IDP1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDP1

Function

Biological processes
TermNameLevelCount
GO:0000959 mitochondrial RNA metabolic process 6 1
GO:0000963 mitochondrial RNA processing 6 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006396 RNA processing 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009894 regulation of catabolic process 4 1
GO:0009987 cellular process 1 1
GO:0010467 gene expression 4 1
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Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 1
GO:0003723 RNA binding 4 1
GO:0005488 binding 1 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1221 1225 PF00656 0.669
CLV_C14_Caspase3-7 454 458 PF00656 0.600
CLV_C14_Caspase3-7 460 464 PF00656 0.462
CLV_C14_Caspase3-7 721 725 PF00656 0.516
CLV_MEL_PAP_1 710 716 PF00089 0.461
CLV_NRD_NRD_1 28 30 PF00675 0.732
CLV_NRD_NRD_1 323 325 PF00675 0.411
CLV_NRD_NRD_1 373 375 PF00675 0.423
CLV_NRD_NRD_1 410 412 PF00675 0.462
CLV_NRD_NRD_1 593 595 PF00675 0.581
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1ILX8 Leptomonas seymouri 45% 99%
A0A3Q8IRJ1 Leishmania donovani 100% 100%
A4HPX9 Leishmania braziliensis 73% 100%
E9ATP6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4Q0V2 Leishmania major 92% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS