Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDP0_LEIIN

TriTrypDb:

LINF_360055500

Length:

472

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

A4IDP0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDP0

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	145	149	PF00656	0.696
CLV_C14_Caspase3-7	290	294	PF00656	0.678
CLV_C14_Caspase3-7	386	390	PF00656	0.629
CLV_NRD_NRD_1	119	121	PF00675	0.434
CLV_NRD_NRD_1	15	17	PF00675	0.419
CLV_NRD_NRD_1	171	173	PF00675	0.277
CLV_NRD_NRD_1	215	217	PF00675	0.487
CLV_NRD_NRD_1	252	254	PF00675	0.608
CLV_NRD_NRD_1	329	331	PF00675	0.481
CLV_PCSK_KEX2_1	119	121	PF00082	0.480

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCQ6	Leptomonas seymouri	52%	100%
A0A3Q8IJ09	Leishmania donovani	100%	100%
A0A422P578	Trypanosoma rangeli	30%	100%
A4HPX8	Leishmania braziliensis	72%	100%
D0A4C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
E9ATP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q0V3	Leishmania major	89%	100%
V5BUS9	Trypanosoma cruzi	35%	100%

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