Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDM0_LEIIN

TriTrypDb:

LINF_360053400

Length:

194

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 5
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDM0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDM0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.698
CLV_NRD_NRD_1	109	111	PF00675	0.583
CLV_NRD_NRD_1	148	150	PF00675	0.682
CLV_NRD_NRD_1	2	4	PF00675	0.752
CLV_NRD_NRD_1	65	67	PF00675	0.599
CLV_NRD_NRD_1	73	75	PF00675	0.524
CLV_PCSK_KEX2_1	108	110	PF00082	0.564
CLV_PCSK_KEX2_1	123	125	PF00082	0.439
CLV_PCSK_KEX2_1	131	133	PF00082	0.526
CLV_PCSK_KEX2_1	2	4	PF00082	0.752
CLV_PCSK_KEX2_1	72	74	PF00082	0.553
CLV_PCSK_PC1ET2_1	123	125	PF00082	0.569
CLV_PCSK_PC1ET2_1	131	133	PF00082	0.526
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.553
CLV_PCSK_SKI1_1	117	121	PF00082	0.654
CLV_PCSK_SKI1_1	7	11	PF00082	0.675
DEG_Nend_UBRbox_1	1	4	PF02207	0.760
DOC_PP2B_LxvP_1	25	28	PF13499	0.543
DOC_USP7_MATH_1	26	30	PF00917	0.690
DOC_WW_Pin1_4	7	12	PF00397	0.557
LIG_14-3-3_CanoR_1	164	172	PF00244	0.606
LIG_14-3-3_CanoR_1	20	28	PF00244	0.671
LIG_FHA_1	10	16	PF00498	0.700
LIG_FHA_1	165	171	PF00498	0.675
LIG_FHA_2	59	65	PF00498	0.616
LIG_FHA_2	84	90	PF00498	0.629
LIG_LIR_Apic_2	90	96	PF02991	0.625
LIG_SH2_STAT5	41	44	PF00017	0.515
LIG_TRAF2_1	152	155	PF00917	0.404
LIG_TRAF2_1	95	98	PF00917	0.600
MOD_CK1_1	29	35	PF00069	0.633
MOD_CK1_1	40	46	PF00069	0.672
MOD_CK2_1	165	171	PF00069	0.647
MOD_DYRK1A_RPxSP_1	7	11	PF00069	0.523
MOD_GlcNHglycan	29	32	PF01048	0.639
MOD_GlcNHglycan	42	45	PF01048	0.664
MOD_GSK3_1	15	22	PF00069	0.673
MOD_GSK3_1	186	193	PF00069	0.737
MOD_GSK3_1	26	33	PF00069	0.574
MOD_NEK2_1	55	60	PF00069	0.691
MOD_PIKK_1	19	25	PF00454	0.645
MOD_PKA_2	19	25	PF00069	0.688
MOD_PKA_2	58	64	PF00069	0.662
MOD_Plk_1	37	43	PF00069	0.625
MOD_Plk_4	37	43	PF00069	0.555
MOD_ProDKin_1	7	13	PF00069	0.557
MOD_SUMO_rev_2	180	188	PF00179	0.660
TRG_DiLeu_BaEn_4	97	103	PF01217	0.590
TRG_ER_diArg_1	1	3	PF00400	0.770
TRG_ER_diArg_1	108	110	PF00400	0.623
TRG_ER_diArg_1	57	60	PF00400	0.710
TRG_ER_diArg_1	73	76	PF00400	0.482
TRG_Pf-PMV_PEXEL_1	73	77	PF00026	0.669

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P0M8	Trypanosomatidae	53%	100%
A0A3Q8IGG6	Leishmania donovani	98%	100%
A4HPV8	Leishmania braziliensis	68%	100%
E9ATM5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q0X3	Leishmania major	91%	100%