Mitochondrial ribosomal protein L23

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial RNA binding complex 1 subunit

Species:

Leishmania infantum

UniProt:

A4IDK5_LEIIN

TriTrypDb:

LINF_360030200

Length:

325

Annotations

Annotations by Jardim et al.

Ribosomal Protein, Mitochondrial ribosomal S18

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0000314	organellar small ribosomal subunit	5	1
GO:0005737	cytoplasm	2	1
GO:0005763	mitochondrial small ribosomal subunit	3	1
GO:0015935	small ribosomal subunit	4	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:0098798	mitochondrial protein-containing complex	2	1
GO:0110165	cellular anatomical entity	1	1
GO:1990904	ribonucleoprotein complex	2	1

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Expansion

Sequence features

A4IDK5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDK5

PDB structure(s): 7ane_m

Function

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Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0009894	regulation of catabolic process	4	1
GO:0009895	negative regulation of catabolic process	5	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	175	181	PF00089	0.394
CLV_NRD_NRD_1	237	239	PF00675	0.603
CLV_NRD_NRD_1	55	57	PF00675	0.472
CLV_PCSK_KEX2_1	237	239	PF00082	0.603
CLV_PCSK_KEX2_1	311	313	PF00082	0.461
CLV_PCSK_KEX2_1	57	59	PF00082	0.481
CLV_PCSK_PC1ET2_1	311	313	PF00082	0.461
CLV_PCSK_PC1ET2_1	57	59	PF00082	0.481
CLV_PCSK_SKI1_1	139	143	PF00082	0.380
CLV_PCSK_SKI1_1	164	168	PF00082	0.396

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PD70	Leptomonas seymouri	90%	100%
A0A0S4JTC8	Bodo saltans	67%	100%
A0A3S5H825	Leishmania donovani	100%	100%
A0A422NIU3	Trypanosoma rangeli	84%	100%
A4HP99	Leishmania braziliensis	94%	100%
D0A3A4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	83%	100%
E9AT08	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
Q4Q1J0	Leishmania major	98%	100%
V5BKY9	Trypanosoma cruzi	82%	100%

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