LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IDJ6_LEIIN
TriTrypDb:
LINF_360029300
Length:
375

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDJ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDJ6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 368 370 PF00675 0.674
CLV_NRD_NRD_1 372 374 PF00675 0.689
CLV_PCSK_FUR_1 369 373 PF00082 0.646
CLV_PCSK_KEX2_1 370 372 PF00082 0.684
CLV_PCSK_PC1ET2_1 370 372 PF00082 0.684
CLV_PCSK_PC7_1 367 373 PF00082 0.623
CLV_PCSK_SKI1_1 349 353 PF00082 0.539
CLV_PCSK_SKI1_1 5 9 PF00082 0.327
CLV_PCSK_SKI1_1 94 98 PF00082 0.466
CLV_Separin_Metazoa 305 309 PF03568 0.451
DEG_APCC_DBOX_1 4 12 PF00400 0.310
DEG_Nend_Nbox_1 1 3 PF02207 0.376
DOC_CKS1_1 49 54 PF01111 0.574
DOC_MAPK_gen_1 3 11 PF00069 0.313
DOC_MAPK_gen_1 72 80 PF00069 0.392
DOC_PP2B_LxvP_1 313 316 PF13499 0.527
DOC_PP2B_LxvP_1 95 98 PF13499 0.481
DOC_USP7_MATH_1 218 222 PF00917 0.650
DOC_USP7_MATH_1 252 256 PF00917 0.679
DOC_USP7_MATH_1 331 335 PF00917 0.660
DOC_USP7_MATH_1 363 367 PF00917 0.612
DOC_USP7_MATH_1 53 57 PF00917 0.644
DOC_USP7_UBL2_3 63 67 PF12436 0.511
DOC_WW_Pin1_4 11 16 PF00397 0.465
DOC_WW_Pin1_4 158 163 PF00397 0.608
DOC_WW_Pin1_4 197 202 PF00397 0.653
DOC_WW_Pin1_4 234 239 PF00397 0.429
DOC_WW_Pin1_4 257 262 PF00397 0.663
DOC_WW_Pin1_4 308 313 PF00397 0.600
DOC_WW_Pin1_4 33 38 PF00397 0.475
DOC_WW_Pin1_4 48 53 PF00397 0.714
LIG_14-3-3_CanoR_1 166 172 PF00244 0.642
LIG_14-3-3_CanoR_1 3 8 PF00244 0.397
LIG_14-3-3_CanoR_1 308 312 PF00244 0.485
LIG_14-3-3_CanoR_1 72 81 PF00244 0.454
LIG_Actin_WH2_2 238 253 PF00022 0.468
LIG_FHA_1 118 124 PF00498 0.356
LIG_FHA_1 147 153 PF00498 0.383
LIG_FHA_1 168 174 PF00498 0.589
LIG_FHA_1 245 251 PF00498 0.498
LIG_FHA_1 308 314 PF00498 0.568
LIG_FHA_1 320 326 PF00498 0.519
LIG_FHA_1 37 43 PF00498 0.383
LIG_FHA_1 4 10 PF00498 0.411
LIG_FHA_2 15 21 PF00498 0.455
LIG_LIR_Gen_1 237 245 PF02991 0.444
LIG_LIR_Nem_3 105 111 PF02991 0.472
LIG_LIR_Nem_3 237 243 PF02991 0.444
LIG_SH2_GRB2like 142 145 PF00017 0.451
LIG_SH2_STAP1 82 86 PF00017 0.411
LIG_SH2_STAT5 111 114 PF00017 0.455
LIG_SH3_1 159 165 PF00018 0.494
LIG_SH3_2 49 54 PF14604 0.545
LIG_SH3_3 159 165 PF00018 0.610
LIG_SH3_3 169 175 PF00018 0.548
LIG_SH3_3 263 269 PF00018 0.622
LIG_SH3_3 46 52 PF00018 0.643
LIG_SH3_5 98 102 PF00018 0.523
LIG_SUMO_SIM_anti_2 75 83 PF11976 0.451
LIG_SUMO_SIM_par_1 14 20 PF11976 0.510
MOD_CDK_SPxK_1 48 54 PF00069 0.512
MOD_CK1_1 14 20 PF00069 0.529
MOD_CK1_1 270 276 PF00069 0.686
MOD_CK1_1 334 340 PF00069 0.638
MOD_CK1_1 361 367 PF00069 0.716
MOD_CK1_1 56 62 PF00069 0.582
MOD_CK1_1 68 74 PF00069 0.381
MOD_CK1_1 76 82 PF00069 0.451
MOD_CK2_1 14 20 PF00069 0.530
MOD_DYRK1A_RPxSP_1 308 312 PF00069 0.485
MOD_GlcNHglycan 208 212 PF01048 0.727
MOD_GlcNHglycan 254 257 PF01048 0.715
MOD_GlcNHglycan 317 320 PF01048 0.739
MOD_GlcNHglycan 360 363 PF01048 0.622
MOD_GlcNHglycan 58 61 PF01048 0.711
MOD_GSK3_1 199 206 PF00069 0.686
MOD_GSK3_1 267 274 PF00069 0.637
MOD_GSK3_1 3 10 PF00069 0.448
MOD_GSK3_1 315 322 PF00069 0.678
MOD_GSK3_1 330 337 PF00069 0.588
MOD_GSK3_1 361 368 PF00069 0.544
MOD_GSK3_1 68 75 PF00069 0.466
MOD_N-GLC_1 197 202 PF02516 0.634
MOD_N-GLC_1 271 276 PF02516 0.734
MOD_NEK2_1 118 123 PF00069 0.460
MOD_NEK2_1 146 151 PF00069 0.389
MOD_NEK2_1 153 158 PF00069 0.392
MOD_NEK2_1 307 312 PF00069 0.568
MOD_NEK2_1 358 363 PF00069 0.602
MOD_NEK2_1 7 12 PF00069 0.364
MOD_PIKK_1 118 124 PF00454 0.416
MOD_PIKK_1 19 25 PF00454 0.428
MOD_PIKK_1 199 205 PF00454 0.640
MOD_PKA_2 307 313 PF00069 0.681
MOD_PKA_2 53 59 PF00069 0.641
MOD_PKA_2 73 79 PF00069 0.506
MOD_Plk_4 76 82 PF00069 0.434
MOD_ProDKin_1 11 17 PF00069 0.457
MOD_ProDKin_1 158 164 PF00069 0.612
MOD_ProDKin_1 197 203 PF00069 0.654
MOD_ProDKin_1 234 240 PF00069 0.427
MOD_ProDKin_1 257 263 PF00069 0.662
MOD_ProDKin_1 308 314 PF00069 0.605
MOD_ProDKin_1 33 39 PF00069 0.472
MOD_ProDKin_1 48 54 PF00069 0.724
MOD_SUMO_rev_2 31 37 PF00179 0.471
TRG_DiLeu_BaEn_1 92 97 PF01217 0.432
TRG_DiLeu_BaLyEn_6 173 178 PF01217 0.562
TRG_DiLeu_BaLyEn_6 91 96 PF01217 0.455
TRG_ENDOCYTIC_2 155 158 PF00928 0.480
TRG_ER_diArg_1 2 5 PF00400 0.332
TRG_ER_diArg_1 369 372 PF00400 0.642
TRG_NLS_MonoCore_2 368 373 PF00514 0.647
TRG_NLS_MonoExtC_3 368 373 PF00514 0.647
TRG_NLS_MonoExtN_4 367 374 PF00514 0.643

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7A7 Leptomonas seymouri 40% 98%
A0A1X0P7M9 Trypanosomatidae 28% 100%
A0A3Q8IW00 Leishmania donovani 100% 100%
A4HP91 Leishmania braziliensis 70% 99%
E9ASZ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
Q4Q1J9 Leishmania major 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS