Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDF4_LEIIN

TriTrypDb:

LINF_360024700

Length:

569

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4IDF4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDF4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.605
CLV_MEL_PAP_1	207	213	PF00089	0.408
CLV_NRD_NRD_1	148	150	PF00675	0.412
CLV_NRD_NRD_1	172	174	PF00675	0.361
CLV_NRD_NRD_1	242	244	PF00675	0.394
CLV_NRD_NRD_1	286	288	PF00675	0.590
CLV_NRD_NRD_1	3	5	PF00675	0.406
CLV_NRD_NRD_1	40	42	PF00675	0.420
CLV_NRD_NRD_1	411	413	PF00675	0.249
CLV_NRD_NRD_1	443	445	PF00675	0.261
CLV_NRD_NRD_1	459	461	PF00675	0.295
CLV_NRD_NRD_1	527	529	PF00675	0.324
CLV_NRD_NRD_1	62	64	PF00675	0.426
CLV_PCSK_FUR_1	60	64	PF00082	0.426
CLV_PCSK_KEX2_1	148	150	PF00082	0.412
CLV_PCSK_KEX2_1	171	173	PF00082	0.354
CLV_PCSK_KEX2_1	241	243	PF00082	0.395
CLV_PCSK_KEX2_1	286	288	PF00082	0.590
CLV_PCSK_KEX2_1	3	5	PF00082	0.406
CLV_PCSK_KEX2_1	40	42	PF00082	0.420
CLV_PCSK_KEX2_1	411	413	PF00082	0.249
CLV_PCSK_KEX2_1	443	445	PF00082	0.261
CLV_PCSK_KEX2_1	459	461	PF00082	0.295
CLV_PCSK_KEX2_1	529	531	PF00082	0.323
CLV_PCSK_KEX2_1	60	62	PF00082	0.426
CLV_PCSK_PC1ET2_1	529	531	PF00082	0.323
CLV_PCSK_PC7_1	57	63	PF00082	0.425
CLV_PCSK_SKI1_1	149	153	PF00082	0.403
CLV_PCSK_SKI1_1	334	338	PF00082	0.337
CLV_PCSK_SKI1_1	411	415	PF00082	0.241
CLV_Separin_Metazoa	13	17	PF03568	0.619
DEG_APCC_DBOX_1	333	341	PF00400	0.537
DEG_Nend_Nbox_1	1	3	PF02207	0.612
DEG_ODPH_VHL_1	369	382	PF01847	0.460
DOC_PP2B_LxvP_1	294	297	PF13499	0.343
DOC_USP7_MATH_1	109	113	PF00917	0.571
DOC_USP7_MATH_1	119	123	PF00917	0.580
DOC_USP7_MATH_1	147	151	PF00917	0.609
DOC_USP7_MATH_1	262	266	PF00917	0.199
DOC_USP7_MATH_1	302	306	PF00917	0.309
DOC_USP7_MATH_1	465	469	PF00917	0.565
DOC_USP7_MATH_1	496	500	PF00917	0.469
DOC_USP7_MATH_1	89	93	PF00917	0.574
DOC_WW_Pin1_4	292	297	PF00397	0.356
DOC_WW_Pin1_4	323	328	PF00397	0.199
DOC_WW_Pin1_4	40	45	PF00397	0.616
DOC_WW_Pin1_4	522	527	PF00397	0.530
LIG_14-3-3_CanoR_1	106	113	PF00244	0.573
LIG_14-3-3_CanoR_1	129	134	PF00244	0.608
LIG_14-3-3_CanoR_1	148	154	PF00244	0.605
LIG_14-3-3_CanoR_1	286	296	PF00244	0.377
LIG_14-3-3_CanoR_1	306	310	PF00244	0.199
LIG_14-3-3_CanoR_1	385	394	PF00244	0.450
LIG_14-3-3_CanoR_1	396	403	PF00244	0.485
LIG_14-3-3_CanoR_1	40	44	PF00244	0.616
LIG_14-3-3_CanoR_1	481	487	PF00244	0.478
LIG_APCC_ABBA_1	537	542	PF00400	0.497
LIG_APCC_ABBAyCdc20_2	536	542	PF00400	0.500
LIG_CSL_BTD_1	279	282	PF09270	0.389
LIG_FHA_1	261	267	PF00498	0.199
LIG_FHA_1	306	312	PF00498	0.199
LIG_FHA_1	33	39	PF00498	0.620
LIG_FHA_1	396	402	PF00498	0.486
LIG_FHA_1	542	548	PF00498	0.456
LIG_FHA_1	75	81	PF00498	0.592
LIG_FHA_2	150	156	PF00498	0.600
LIG_FHA_2	384	390	PF00498	0.442
LIG_FHA_2	45	51	PF00498	0.612
LIG_KLC1_Yacidic_2	546	550	PF13176	0.444
LIG_LIR_Apic_2	231	235	PF02991	0.609
LIG_LIR_Gen_1	155	163	PF02991	0.596
LIG_LIR_Gen_1	295	304	PF02991	0.325
LIG_LIR_Gen_1	480	490	PF02991	0.475
LIG_LIR_Gen_1	85	94	PF02991	0.573
LIG_LIR_Nem_3	155	161	PF02991	0.603
LIG_LIR_Nem_3	295	301	PF02991	0.330
LIG_LIR_Nem_3	440	445	PF02991	0.465
LIG_LIR_Nem_3	480	486	PF02991	0.483
LIG_LIR_Nem_3	85	91	PF02991	0.576
LIG_NRBOX	548	554	PF00104	0.435
LIG_Pex14_1	410	414	PF04695	0.451
LIG_SH2_CRK	335	339	PF00017	0.534
LIG_SH2_NCK_1	516	520	PF00017	0.547
LIG_SH2_STAP1	335	339	PF00017	0.534
LIG_SH2_STAT5	303	306	PF00017	0.310
LIG_SH2_STAT5	415	418	PF00017	0.424
LIG_SH2_STAT5	423	426	PF00017	0.424
LIG_SH2_STAT5	445	448	PF00017	0.461
LIG_SH2_STAT5	502	505	PF00017	0.452
LIG_SH2_STAT5	516	519	PF00017	0.546
LIG_SH2_STAT5	548	551	PF00017	0.433
LIG_SH2_STAT5	555	558	PF00017	0.451
LIG_SH3_3	150	156	PF00018	0.600
LIG_SH3_3	232	238	PF00018	0.612
LIG_SH3_3	276	282	PF00018	0.391
LIG_SH3_3	31	37	PF00018	0.618
LIG_SH3_3	321	327	PF00018	0.199
LIG_SH3_3	443	449	PF00018	0.455
LIG_Sin3_3	336	343	PF02671	0.534
LIG_SUMO_SIM_anti_2	308	313	PF11976	0.199
LIG_SUMO_SIM_par_1	307	313	PF11976	0.199
LIG_TRAF2_1	163	166	PF00917	0.558
MOD_CDC14_SPxK_1	525	528	PF00782	0.372
MOD_CDK_SPxK_1	522	528	PF00069	0.380
MOD_CDK_SPxxK_3	522	529	PF00069	0.379
MOD_CK1_1	104	110	PF00069	0.435
MOD_CK1_1	111	117	PF00069	0.446
MOD_CK1_1	250	256	PF00069	0.199
MOD_CK1_1	269	275	PF00069	0.462
MOD_CK1_1	288	294	PF00069	0.459
MOD_CK1_1	305	311	PF00069	0.199
MOD_CK1_1	39	45	PF00069	0.502
MOD_CK1_1	463	469	PF00069	0.426
MOD_CK1_1	489	495	PF00069	0.313
MOD_CK1_1	92	98	PF00069	0.423
MOD_CK2_1	356	362	PF00069	0.269
MOD_CK2_1	383	389	PF00069	0.259
MOD_CK2_1	90	96	PF00069	0.437
MOD_GlcNHglycan	122	125	PF01048	0.469
MOD_GlcNHglycan	136	139	PF01048	0.486
MOD_GlcNHglycan	149	152	PF01048	0.485
MOD_GlcNHglycan	249	252	PF01048	0.472
MOD_GlcNHglycan	254	257	PF01048	0.199
MOD_GlcNHglycan	287	290	PF01048	0.470
MOD_GlcNHglycan	312	315	PF01048	0.199
MOD_GlcNHglycan	4	7	PF01048	0.478
MOD_GlcNHglycan	465	468	PF01048	0.434
MOD_GlcNHglycan	472	475	PF01048	0.370
MOD_GlcNHglycan	488	491	PF01048	0.287
MOD_GlcNHglycan	557	560	PF01048	0.284
MOD_GlcNHglycan	65	71	PF01048	0.509
MOD_GSK3_1	100	107	PF00069	0.432
MOD_GSK3_1	108	115	PF00069	0.441
MOD_GSK3_1	182	189	PF00069	0.509
MOD_GSK3_1	20	27	PF00069	0.510
MOD_GSK3_1	243	250	PF00069	0.475
MOD_GSK3_1	262	269	PF00069	0.199
MOD_GSK3_1	281	288	PF00069	0.466
MOD_GSK3_1	32	39	PF00069	0.507
MOD_GSK3_1	352	359	PF00069	0.281
MOD_GSK3_1	40	47	PF00069	0.501
MOD_GSK3_1	433	440	PF00069	0.254
MOD_GSK3_1	465	472	PF00069	0.418
MOD_GSK3_1	482	489	PF00069	0.302
MOD_GSK3_1	90	97	PF00069	0.432
MOD_LATS_1	184	190	PF00433	0.508
MOD_LATS_1	383	389	PF00433	0.259
MOD_N-GLC_1	156	161	PF02516	0.486
MOD_NEK2_1	260	265	PF00069	0.199
MOD_NEK2_1	352	357	PF00069	0.287
MOD_NEK2_1	424	429	PF00069	0.240
MOD_NEK2_1	94	99	PF00069	0.417
MOD_NEK2_2	262	267	PF00069	0.199
MOD_PIKK_1	281	287	PF00454	0.466
MOD_PIKK_1	395	401	PF00454	0.316
MOD_PK_1	129	135	PF00069	0.493
MOD_PK_1	342	348	PF00069	0.342
MOD_PK_1	460	466	PF00069	0.384
MOD_PKA_1	241	247	PF00069	0.473
MOD_PKA_2	105	111	PF00069	0.435
MOD_PKA_2	128	134	PF00069	0.489
MOD_PKA_2	147	153	PF00069	0.489
MOD_PKA_2	15	21	PF00069	0.504
MOD_PKA_2	2	8	PF00069	0.484
MOD_PKA_2	241	247	PF00069	0.473
MOD_PKA_2	285	291	PF00069	0.468
MOD_PKA_2	305	311	PF00069	0.199
MOD_PKA_2	39	45	PF00069	0.502
MOD_PKA_2	395	401	PF00069	0.316
MOD_PKB_1	241	249	PF00069	0.474
MOD_PKB_1	435	443	PF00069	0.276
MOD_PKB_1	479	487	PF00069	0.315
MOD_Plk_1	156	162	PF00069	0.479
MOD_Plk_1	437	443	PF00069	0.281
MOD_Plk_4	149	155	PF00069	0.483
MOD_Plk_4	157	163	PF00069	0.474
MOD_Plk_4	20	26	PF00069	0.510
MOD_Plk_4	289	295	PF00069	0.451
MOD_Plk_4	496	502	PF00069	0.297
MOD_Plk_4	548	554	PF00069	0.250
MOD_ProDKin_1	292	298	PF00069	0.413
MOD_ProDKin_1	323	329	PF00069	0.199
MOD_ProDKin_1	40	46	PF00069	0.501
MOD_ProDKin_1	522	528	PF00069	0.380
MOD_SUMO_for_1	199	202	PF00179	0.497
TRG_DiLeu_BaEn_1	10	15	PF01217	0.501
TRG_ENDOCYTIC_2	335	338	PF00928	0.391
TRG_ENDOCYTIC_2	423	426	PF00928	0.234
TRG_ENDOCYTIC_2	516	519	PF00928	0.405
TRG_ER_diArg_1	147	149	PF00400	0.500
TRG_ER_diArg_1	170	173	PF00400	0.414
TRG_ER_diArg_1	2	4	PF00400	0.495
TRG_ER_diArg_1	240	243	PF00400	0.474
TRG_ER_diArg_1	410	412	PF00400	0.288
TRG_ER_diArg_1	442	444	PF00400	0.288
TRG_ER_diArg_1	458	460	PF00400	0.340
TRG_ER_diArg_1	535	538	PF00400	0.360
TRG_ER_diArg_1	60	63	PF00400	0.518
TRG_NLS_MonoCore_2	527	532	PF00514	0.367
TRG_NLS_MonoExtC_3	528	534	PF00514	0.364
TRG_NLS_MonoExtN_4	526	533	PF00514	0.369
TRG_Pf-PMV_PEXEL_1	385	389	PF00026	0.258
TRG_Pf-PMV_PEXEL_1	530	534	PF00026	0.362