MORN repeat family protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat - putative

Species:

Leishmania infantum

UniProt:

A4IDF2_LEIIN

TriTrypDb:

LINF_360024500

Length:

938

Annotations

Annotations by Jardim et al.

Flagella, MORN repeat

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4IDF2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDF2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	231	235	PF00656	0.462
CLV_C14_Caspase3-7	454	458	PF00656	0.278
CLV_C14_Caspase3-7	501	505	PF00656	0.335
CLV_C14_Caspase3-7	775	779	PF00656	0.453
CLV_C14_Caspase3-7	811	815	PF00656	0.421
CLV_C14_Caspase3-7	881	885	PF00656	0.408
CLV_C14_Caspase3-7	886	890	PF00656	0.377
CLV_C14_Caspase3-7	920	924	PF00656	0.335
CLV_NRD_NRD_1	459	461	PF00675	0.335
CLV_NRD_NRD_1	467	469	PF00675	0.335
CLV_NRD_NRD_1	506	508	PF00675	0.335
CLV_NRD_NRD_1	732	734	PF00675	0.453
CLV_NRD_NRD_1	823	825	PF00675	0.633
CLV_PCSK_KEX2_1	459	461	PF00082	0.335
CLV_PCSK_KEX2_1	467	469	PF00082	0.335
CLV_PCSK_KEX2_1	506	508	PF00082	0.335
CLV_PCSK_KEX2_1	648	650	PF00082	0.335
CLV_PCSK_KEX2_1	732	734	PF00082	0.453
CLV_PCSK_KEX2_1	823	825	PF00082	0.646
CLV_PCSK_PC1ET2_1	648	650	PF00082	0.325
CLV_PCSK_SKI1_1	155	159	PF00082	0.666
CLV_PCSK_SKI1_1	74	78	PF00082	0.397
DEG_APCC_DBOX_1	13	21	PF00400	0.677
DEG_SPOP_SBC_1	8	12	PF00917	0.724
DOC_ANK_TNKS_1	489	496	PF00023	0.493
DOC_CDC14_PxL_1	191	199	PF14671	0.654
DOC_CYCLIN_yCln2_LP_2	56	62	PF00134	0.424
DOC_MAPK_RevD_3	424	438	PF00069	0.342
DOC_PP1_RVXF_1	325	331	PF00149	0.519
DOC_USP7_MATH_1	175	179	PF00917	0.689
DOC_USP7_MATH_1	219	223	PF00917	0.613
DOC_USP7_MATH_1	346	350	PF00917	0.690
DOC_USP7_MATH_1	45	49	PF00917	0.506
DOC_USP7_MATH_1	663	667	PF00917	0.655
DOC_USP7_MATH_1	8	12	PF00917	0.752
DOC_USP7_MATH_1	827	831	PF00917	0.465
DOC_USP7_MATH_1	898	902	PF00917	0.553
DOC_USP7_MATH_2	244	250	PF00917	0.661
DOC_USP7_MATH_2	669	675	PF00917	0.479
DOC_USP7_UBL2_3	437	441	PF12436	0.278
DOC_WW_Pin1_4	171	176	PF00397	0.658
DOC_WW_Pin1_4	318	323	PF00397	0.560
DOC_WW_Pin1_4	32	37	PF00397	0.519
DOC_WW_Pin1_4	360	365	PF00397	0.739
DOC_WW_Pin1_4	489	494	PF00397	0.561
DOC_WW_Pin1_4	94	99	PF00397	0.487
LIG_14-3-3_CanoR_1	138	147	PF00244	0.501
LIG_14-3-3_CanoR_1	301	310	PF00244	0.542
LIG_14-3-3_CanoR_1	692	700	PF00244	0.453
LIG_14-3-3_CanoR_1	7	17	PF00244	0.688
LIG_14-3-3_CanoR_1	869	878	PF00244	0.453
LIG_Actin_WH2_2	773	790	PF00022	0.306
LIG_BIR_III_2	814	818	PF00653	0.519
LIG_BRCT_BRCA1_1	140	144	PF00533	0.426
LIG_BRCT_BRCA1_1	33	37	PF00533	0.586
LIG_BRCT_BRCA1_1	923	927	PF00533	0.325
LIG_Clathr_ClatBox_2	309	314	PF01394	0.572
LIG_CtBP_PxDLS_1	322	326	PF00389	0.530
LIG_deltaCOP1_diTrp_1	470	478	PF00928	0.335
LIG_EH1_1	403	411	PF00400	0.517
LIG_FHA_1	115	121	PF00498	0.419
LIG_FHA_1	373	379	PF00498	0.615
LIG_FHA_1	51	57	PF00498	0.437
LIG_FHA_1	741	747	PF00498	0.473
LIG_FHA_1	805	811	PF00498	0.580
LIG_FHA_2	148	154	PF00498	0.629
LIG_FHA_2	252	258	PF00498	0.628
LIG_FHA_2	27	33	PF00498	0.483
LIG_FHA_2	319	325	PF00498	0.541
LIG_FHA_2	387	393	PF00498	0.523
LIG_FHA_2	558	564	PF00498	0.451
LIG_FHA_2	692	698	PF00498	0.453
LIG_FHA_2	918	924	PF00498	0.335
LIG_Integrin_RGD_1	229	231	PF01839	0.453
LIG_LIR_Apic_2	312	317	PF02991	0.573
LIG_LIR_Apic_2	603	609	PF02991	0.453
LIG_LIR_Apic_2	80	86	PF02991	0.474
LIG_LIR_Nem_3	415	420	PF02991	0.605
LIG_LIR_Nem_3	48	54	PF02991	0.404
LIG_LIR_Nem_3	542	547	PF02991	0.408
LIG_LIR_Nem_3	747	751	PF02991	0.437
LIG_MLH1_MIPbox_1	140	144	PF16413	0.426
LIG_PDZ_Class_2	933	938	PF00595	0.441
LIG_Pex14_2	143	147	PF04695	0.521
LIG_Pex14_2	330	334	PF04695	0.576
LIG_Pex14_2	400	404	PF04695	0.447
LIG_Pex14_2	78	82	PF04695	0.456
LIG_Pex14_2	927	931	PF04695	0.417
LIG_PTB_Apo_2	930	937	PF02174	0.478
LIG_PTB_Phospho_1	930	936	PF10480	0.477
LIG_SH2_NCK_1	241	245	PF00017	0.569
LIG_SH2_PTP2	606	609	PF00017	0.335
LIG_SH2_SRC	124	127	PF00017	0.537
LIG_SH2_SRC	812	815	PF00017	0.445
LIG_SH2_STAT3	474	477	PF00017	0.335
LIG_SH2_STAT3	652	655	PF00017	0.389
LIG_SH2_STAT5	113	116	PF00017	0.484
LIG_SH2_STAT5	124	127	PF00017	0.415
LIG_SH2_STAT5	224	227	PF00017	0.354
LIG_SH2_STAT5	451	454	PF00017	0.335
LIG_SH2_STAT5	51	54	PF00017	0.387
LIG_SH2_STAT5	606	609	PF00017	0.335
LIG_SH2_STAT5	640	643	PF00017	0.335
LIG_SH2_STAT5	772	775	PF00017	0.453
LIG_SH2_STAT5	812	815	PF00017	0.445
LIG_SH2_STAT5	832	835	PF00017	0.183
LIG_SH3_1	418	424	PF00018	0.534
LIG_SH3_3	102	108	PF00018	0.437
LIG_SH3_3	186	192	PF00018	0.660
LIG_SH3_3	290	296	PF00018	0.758
LIG_SH3_3	30	36	PF00018	0.601
LIG_SH3_3	373	379	PF00018	0.581
LIG_SH3_3	380	386	PF00018	0.630
LIG_SH3_3	418	424	PF00018	0.480
LIG_SH3_3	654	660	PF00018	0.579
LIG_SUMO_SIM_par_1	52	57	PF11976	0.437
LIG_TRAF2_1	150	153	PF00917	0.605
LIG_TRAF2_1	243	246	PF00917	0.640
LIG_TRAF2_1	321	324	PF00917	0.531
LIG_TRAF2_1	581	584	PF00917	0.421
LIG_TYR_ITIM	49	54	PF00017	0.386
LIG_TYR_ITIM	746	751	PF00017	0.478
LIG_WRC_WIRS_1	401	406	PF05994	0.455
MOD_CK1_1	12	18	PF00069	0.632
MOD_CK1_1	128	134	PF00069	0.561
MOD_CK1_1	174	180	PF00069	0.566
MOD_CK1_1	312	318	PF00069	0.579
MOD_CK1_1	50	56	PF00069	0.507
MOD_CK1_1	638	644	PF00069	0.335
MOD_CK1_1	759	765	PF00069	0.491
MOD_CK1_1	874	880	PF00069	0.414
MOD_CK2_1	147	153	PF00069	0.590
MOD_CK2_1	256	262	PF00069	0.616
MOD_CK2_1	318	324	PF00069	0.544
MOD_CK2_1	386	392	PF00069	0.553
MOD_CK2_1	719	725	PF00069	0.498
MOD_CK2_1	850	856	PF00069	0.335
MOD_CMANNOS	311	314	PF00535	0.582
MOD_Cter_Amidation	457	460	PF01082	0.335
MOD_Cter_Amidation	504	507	PF01082	0.335
MOD_GlcNHglycan	126	130	PF01048	0.590
MOD_GlcNHglycan	177	180	PF01048	0.735
MOD_GlcNHglycan	20	23	PF01048	0.599
MOD_GlcNHglycan	203	206	PF01048	0.686
MOD_GlcNHglycan	208	211	PF01048	0.661
MOD_GlcNHglycan	214	217	PF01048	0.560
MOD_GlcNHglycan	288	291	PF01048	0.572
MOD_GlcNHglycan	311	314	PF01048	0.582
MOD_GlcNHglycan	509	512	PF01048	0.321
MOD_GlcNHglycan	632	635	PF01048	0.453
MOD_GlcNHglycan	649	652	PF01048	0.335
MOD_GlcNHglycan	665	668	PF01048	0.501
MOD_GlcNHglycan	687	690	PF01048	0.335
MOD_GlcNHglycan	710	714	PF01048	0.278
MOD_GlcNHglycan	740	743	PF01048	0.335
MOD_GlcNHglycan	873	876	PF01048	0.335
MOD_GlcNHglycan	899	903	PF01048	0.364
MOD_GSK3_1	164	171	PF00069	0.737
MOD_GSK3_1	177	184	PF00069	0.642
MOD_GSK3_1	2	9	PF00069	0.668
MOD_GSK3_1	312	319	PF00069	0.580
MOD_GSK3_1	344	351	PF00069	0.734
MOD_GSK3_1	360	367	PF00069	0.548
MOD_GSK3_1	368	375	PF00069	0.576
MOD_GSK3_1	50	57	PF00069	0.557
MOD_GSK3_1	507	514	PF00069	0.389
MOD_GSK3_1	557	564	PF00069	0.460
MOD_GSK3_1	715	722	PF00069	0.570
MOD_GSK3_1	740	747	PF00069	0.419
MOD_GSK3_1	755	762	PF00069	0.450
MOD_GSK3_1	917	924	PF00069	0.324
MOD_LATS_1	754	760	PF00433	0.518
MOD_N-GLC_1	18	23	PF02516	0.665
MOD_NEK2_1	1	6	PF00069	0.699
MOD_NEK2_1	18	23	PF00069	0.530
MOD_NEK2_1	201	206	PF00069	0.659
MOD_NEK2_1	248	253	PF00069	0.737
MOD_NEK2_1	334	339	PF00069	0.597
MOD_NEK2_1	372	377	PF00069	0.669
MOD_NEK2_1	400	405	PF00069	0.449
MOD_NEK2_1	447	452	PF00069	0.394
MOD_NEK2_1	77	82	PF00069	0.388
MOD_NEK2_2	114	119	PF00069	0.435
MOD_NEK2_2	219	224	PF00069	0.650
MOD_NEK2_2	783	788	PF00069	0.306
MOD_NEK2_2	922	927	PF00069	0.335
MOD_OFUCOSY	75	81	PF10250	0.388
MOD_PIKK_1	246	252	PF00454	0.686
MOD_PIKK_1	279	285	PF00454	0.708
MOD_PIKK_1	54	60	PF00454	0.541
MOD_PIKK_1	561	567	PF00454	0.574
MOD_PIKK_1	740	746	PF00454	0.421
MOD_PIKK_1	843	849	PF00454	0.335
MOD_PK_1	756	762	PF00069	0.504
MOD_PK_1	850	856	PF00069	0.335
MOD_PK_1	883	889	PF00069	0.378
MOD_PKA_2	206	212	PF00069	0.632
MOD_PKA_2	6	12	PF00069	0.583
MOD_PKA_2	671	677	PF00069	0.471
MOD_PKA_2	691	697	PF00069	0.326
MOD_PKA_2	715	721	PF00069	0.512
MOD_PKA_2	755	761	PF00069	0.571
MOD_PKA_2	868	874	PF00069	0.335
MOD_PKB_1	867	875	PF00069	0.278
MOD_Plk_1	261	267	PF00069	0.712
MOD_Plk_1	368	374	PF00069	0.686
MOD_Plk_1	447	453	PF00069	0.414
MOD_Plk_1	922	928	PF00069	0.325
MOD_Plk_2-3	408	414	PF00069	0.519
MOD_Plk_2-3	540	546	PF00069	0.414
MOD_Plk_2-3	671	677	PF00069	0.439
MOD_Plk_4	219	225	PF00069	0.551
MOD_Plk_4	248	254	PF00069	0.572
MOD_Plk_4	26	32	PF00069	0.516
MOD_Plk_4	400	406	PF00069	0.455
MOD_Plk_4	47	53	PF00069	0.532
MOD_Plk_4	517	523	PF00069	0.291
MOD_Plk_4	602	608	PF00069	0.453
MOD_Plk_4	635	641	PF00069	0.424
MOD_Plk_4	719	725	PF00069	0.444
MOD_Plk_4	735	741	PF00069	0.335
MOD_Plk_4	772	778	PF00069	0.453
MOD_Plk_4	850	856	PF00069	0.335
MOD_Plk_4	883	889	PF00069	0.382
MOD_Plk_4	922	928	PF00069	0.335
MOD_ProDKin_1	171	177	PF00069	0.659
MOD_ProDKin_1	318	324	PF00069	0.555
MOD_ProDKin_1	32	38	PF00069	0.515
MOD_ProDKin_1	360	366	PF00069	0.735
MOD_ProDKin_1	489	495	PF00069	0.559
MOD_ProDKin_1	94	100	PF00069	0.484
MOD_SUMO_rev_2	34	43	PF00179	0.510
MOD_SUMO_rev_2	411	420	PF00179	0.432
TRG_DiLeu_BaEn_2	460	466	PF01217	0.389
TRG_DiLeu_BaEn_4	323	329	PF01217	0.506
TRG_DiLeu_BaLyEn_6	91	96	PF01217	0.488
TRG_ENDOCYTIC_2	444	447	PF00928	0.314
TRG_ENDOCYTIC_2	51	54	PF00928	0.378
TRG_ENDOCYTIC_2	544	547	PF00928	0.416
TRG_ENDOCYTIC_2	748	751	PF00928	0.433
TRG_ER_diArg_1	466	468	PF00400	0.335
TRG_ER_diArg_1	822	824	PF00400	0.641
TRG_ER_diArg_1	867	870	PF00400	0.258

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I572	Leptomonas seymouri	55%	98%
A0A3S7XAW7	Leishmania donovani	99%	100%
A4HP45	Leishmania braziliensis	78%	100%
E9ASV3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q1P3	Leishmania major	91%	100%