Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDF1_LEIIN

TriTrypDb:

LINF_360024400

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDF1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	198	200	PF00675	0.424
CLV_NRD_NRD_1	41	43	PF00675	0.620
CLV_PCSK_KEX2_1	13	15	PF00082	0.482
CLV_PCSK_KEX2_1	198	200	PF00082	0.424
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.482
CLV_PCSK_PC7_1	9	15	PF00082	0.443
CLV_PCSK_SKI1_1	138	142	PF00082	0.501
CLV_PCSK_SKI1_1	198	202	PF00082	0.415
CLV_PCSK_SKI1_1	27	31	PF00082	0.394
DEG_APCC_DBOX_1	177	185	PF00400	0.455
DEG_Nend_UBRbox_3	1	3	PF02207	0.407
DOC_MAPK_gen_1	42	51	PF00069	0.419
DOC_USP7_MATH_1	87	91	PF00917	0.687
LIG_14-3-3_CanoR_1	230	236	PF00244	0.436
LIG_14-3-3_CanoR_1	27	37	PF00244	0.395
LIG_14-3-3_CanoR_1	42	46	PF00244	0.334
LIG_APCC_ABBA_1	49	54	PF00400	0.372
LIG_APCC_ABBAyCdc20_2	48	54	PF00400	0.375
LIG_FHA_1	45	51	PF00498	0.379
LIG_FHA_2	19	25	PF00498	0.365
LIG_FHA_2	235	241	PF00498	0.456
LIG_PDZ_Class_3	243	248	PF00595	0.524
LIG_Pex14_2	41	45	PF04695	0.347
LIG_SH2_NCK_1	213	217	PF00017	0.469
LIG_SH2_STAP1	52	56	PF00017	0.372
LIG_SH2_STAP1	68	72	PF00017	0.349
LIG_SH2_STAT3	109	112	PF00017	0.458
LIG_SH3_3	238	244	PF00018	0.487
LIG_TRAF2_1	194	197	PF00917	0.437
LIG_TRAF2_1	78	81	PF00917	0.423
LIG_UBA3_1	7	13	PF00899	0.362
MOD_CK1_1	44	50	PF00069	0.350
MOD_CK1_1	94	100	PF00069	0.623
MOD_CK2_1	123	129	PF00069	0.537
MOD_CK2_1	18	24	PF00069	0.355
MOD_CK2_1	234	240	PF00069	0.437
MOD_GlcNHglycan	56	59	PF01048	0.388
MOD_GlcNHglycan	83	86	PF01048	0.475
MOD_GSK3_1	87	94	PF00069	0.654
MOD_N-GLC_1	138	143	PF02516	0.484
MOD_N-GLC_1	54	59	PF02516	0.451
MOD_NEK2_1	234	239	PF00069	0.482
MOD_NEK2_1	41	46	PF00069	0.351
MOD_PIKK_1	229	235	PF00454	0.428
MOD_PKA_1	13	19	PF00069	0.348
MOD_PKA_2	13	19	PF00069	0.348
MOD_PKA_2	221	227	PF00069	0.423
MOD_PKA_2	229	235	PF00069	0.386
MOD_PKA_2	41	47	PF00069	0.360
MOD_Plk_1	138	144	PF00069	0.414
MOD_Plk_1	54	60	PF00069	0.447
MOD_Plk_2-3	18	24	PF00069	0.355
MOD_SUMO_for_1	153	156	PF00179	0.450
TRG_DiLeu_BaEn_1	32	37	PF01217	0.396
TRG_DiLeu_BaEn_3	196	202	PF01217	0.422
TRG_DiLeu_BaLyEn_6	6	11	PF01217	0.444
TRG_DiLeu_LyEn_5	32	37	PF01217	0.396
TRG_ER_diArg_1	198	200	PF00400	0.424

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HP44	Leishmania braziliensis	69%	100%
Q4Q1P4	Leishmania major	90%	100%