LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IDE8_LEIIN
TriTrypDb:
LINF_360024100
Length:
106

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

A4IDE8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDE8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 23 25 PF00675 0.605
CLV_NRD_NRD_1 3 5 PF00675 0.575
CLV_NRD_NRD_1 78 80 PF00675 0.364
CLV_PCSK_KEX2_1 23 25 PF00082 0.605
CLV_PCSK_KEX2_1 3 5 PF00082 0.575
CLV_PCSK_KEX2_1 77 79 PF00082 0.392
CLV_PCSK_PC7_1 74 80 PF00082 0.443
CLV_PCSK_SKI1_1 3 7 PF00082 0.623
DEG_MDM2_SWIB_1 48 56 PF02201 0.404
DEG_Nend_Nbox_1 1 3 PF02207 0.386
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P701 Leptomonas seymouri 77% 100%
A0A1X0P839 Trypanosomatidae 55% 100%
A0A3Q8IK31 Leishmania donovani 100% 100%
A0A422NLR1 Trypanosoma rangeli 57% 100%
A4HP41 Leishmania braziliensis 89% 100%
D0A325 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 100%
E9ASU9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q4Q1P7 Leishmania major 97% 100%
V5B4H5 Trypanosoma cruzi 56% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS