Metal Binding, poly-zinc finger 2
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 20 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4IDD4
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006417 | regulation of translation | 6 | 1 |
| GO:0009889 | regulation of biosynthetic process | 4 | 1 |
| GO:0009891 | positive regulation of biosynthetic process | 5 | 1 |
| GO:0009893 | positive regulation of metabolic process | 4 | 1 |
| GO:0010468 | regulation of gene expression | 5 | 1 |
| GO:0010556 | regulation of macromolecule biosynthetic process | 5 | 1 |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 6 | 1 |
| GO:0010604 | positive regulation of macromolecule metabolic process | 5 | 1 |
| GO:0010608 | post-transcriptional regulation of gene expression | 6 | 1 |
| GO:0010628 | positive regulation of gene expression | 6 | 1 |
| GO:0019222 | regulation of metabolic process | 3 | 1 |
| GO:0031323 | regulation of cellular metabolic process | 4 | 1 |
| GO:0031325 | positive regulation of cellular metabolic process | 5 | 1 |
| GO:0031326 | regulation of cellular biosynthetic process | 5 | 1 |
| GO:0031328 | positive regulation of cellular biosynthetic process | 6 | 1 |
| GO:0034248 | regulation of amide metabolic process | 5 | 1 |
| GO:0034250 | positive regulation of amide metabolic process | 6 | 1 |
| GO:0045727 | positive regulation of translation | 7 | 1 |
| GO:0048518 | positive regulation of biological process | 3 | 1 |
| GO:0048522 | positive regulation of cellular process | 4 | 1 |
| GO:0050789 | regulation of biological process | 2 | 1 |
| GO:0050794 | regulation of cellular process | 3 | 1 |
| GO:0051171 | regulation of nitrogen compound metabolic process | 4 | 1 |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 5 | 1 |
| GO:0051246 | regulation of protein metabolic process | 5 | 1 |
| GO:0051247 | positive regulation of protein metabolic process | 6 | 1 |
| GO:0060255 | regulation of macromolecule metabolic process | 4 | 1 |
| GO:0065007 | biological regulation | 1 | 1 |
| GO:0080090 | regulation of primary metabolic process | 4 | 1 |
| GO:2000112 | obsolete regulation of cellular macromolecule biosynthetic process | 6 | 1 |
| GO:2000765 | regulation of cytoplasmic translation | 7 | 1 |
| GO:2000767 | positive regulation of cytoplasmic translation | 8 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 13 |
| GO:0005488 | binding | 1 | 13 |
| GO:0008270 | zinc ion binding | 6 | 13 |
| GO:0043167 | ion binding | 2 | 13 |
| GO:0043169 | cation binding | 3 | 13 |
| GO:0046872 | metal ion binding | 4 | 13 |
| GO:0046914 | transition metal ion binding | 5 | 13 |
| GO:0097159 | organic cyclic compound binding | 2 | 13 |
| GO:1901363 | heterocyclic compound binding | 2 | 13 |
| GO:0003723 | RNA binding | 4 | 1 |
| GO:0003727 | single-stranded RNA binding | 5 | 1 |
| GO:0003729 | mRNA binding | 5 | 1 |
| GO:0045182 | translation regulator activity | 1 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 131 | 135 | PF00656 | 0.204 |
| CLV_C14_Caspase3-7 | 18 | 22 | PF00656 | 0.379 |
| CLV_NRD_NRD_1 | 119 | 121 | PF00675 | 0.315 |
| CLV_NRD_NRD_1 | 128 | 130 | PF00675 | 0.230 |
| CLV_PCSK_KEX2_1 | 111 | 113 | PF00082 | 0.533 |
| CLV_PCSK_PC1ET2_1 | 111 | 113 | PF00082 | 0.543 |
| DOC_USP7_MATH_1 | 110 | 114 | PF00917 | 0.542 |
| DOC_USP7_MATH_1 | 19 | 23 | PF00917 | 0.441 |
| DOC_USP7_UBL2_3 | 117 | 121 | PF12436 | 0.369 |
| LIG_FHA_2 | 41 | 47 | PF00498 | 0.329 |
| LIG_PTAP_UEV_1 | 106 | 111 | PF05743 | 0.491 |
| LIG_SH2_STAT5 | 51 | 54 | PF00017 | 0.353 |
| LIG_SH2_STAT5 | 94 | 97 | PF00017 | 0.369 |
| LIG_SH3_1 | 104 | 110 | PF00018 | 0.315 |
| LIG_SH3_1 | 60 | 66 | PF00018 | 0.315 |
| LIG_SH3_2 | 107 | 112 | PF14604 | 0.526 |
| LIG_SH3_2 | 63 | 68 | PF14604 | 0.502 |
| LIG_SH3_3 | 104 | 110 | PF00018 | 0.315 |
| LIG_SH3_3 | 60 | 66 | PF00018 | 0.237 |
| LIG_TRAF2_1 | 43 | 46 | PF00917 | 0.482 |
| MOD_CK1_1 | 105 | 111 | PF00069 | 0.544 |
| MOD_CK1_1 | 40 | 46 | PF00069 | 0.481 |
| MOD_CK1_1 | 85 | 91 | PF00069 | 0.348 |
| MOD_CK2_1 | 40 | 46 | PF00069 | 0.477 |
| MOD_Cter_Amidation | 122 | 125 | PF01082 | 0.369 |
| MOD_GlcNHglycan | 112 | 115 | PF01048 | 0.441 |
| MOD_GlcNHglycan | 17 | 20 | PF01048 | 0.476 |
| MOD_GlcNHglycan | 21 | 24 | PF01048 | 0.443 |
| MOD_GSK3_1 | 10 | 17 | PF00069 | 0.316 |
| MOD_N-GLC_1 | 75 | 80 | PF02516 | 0.252 |
| MOD_NEK2_2 | 115 | 120 | PF00069 | 0.369 |
| MOD_PIKK_1 | 75 | 81 | PF00454 | 0.252 |
| MOD_Plk_4 | 68 | 74 | PF00069 | 0.478 |
| MOD_SUMO_for_1 | 67 | 70 | PF00179 | 0.505 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1I7B4 | Leptomonas seymouri | 42% | 100% |
| A0A0N1I8Z8 | Leptomonas seymouri | 42% | 100% |
| A0A0N1PD50 | Leptomonas seymouri | 88% | 100% |
| A0A1X0P8V4 | Trypanosomatidae | 45% | 70% |
| A0A3Q8IK17 | Leishmania donovani | 35% | 77% |
| A0A3Q8IKG2 | Leishmania donovani | 39% | 100% |
| A0A3R7K9Q9 | Trypanosoma rangeli | 44% | 70% |
| A0A3S5H821 | Leishmania donovani | 100% | 100% |
| A0A422MWM4 | Trypanosoma rangeli | 33% | 100% |
| A4HP21 | Leishmania braziliensis | 39% | 100% |
| A4HP22 | Leishmania braziliensis | 39% | 100% |
| A4HP24 | Leishmania braziliensis | 91% | 100% |
| A4IDD1 | Leishmania infantum | 39% | 100% |
| A4IDD2 | Leishmania infantum | 39% | 100% |
| D0A311 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 36% | 96% |
| E9AST2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 39% | 100% |
| E9AST3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 35% | 100% |
| E9AST5 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 96% | 100% |
| O42395 | Gallus gallus | 40% | 78% |
| P36627 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 37% | 75% |
| P53849 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 40% | 88% |
| P53996 | Mus musculus | 40% | 76% |
| P62633 | Homo sapiens | 39% | 76% |
| P62634 | Rattus norvegicus | 39% | 76% |
| Q3T0Q6 | Bos taurus | 39% | 79% |
| Q4Q1R1 | Leishmania major | 96% | 100% |
| Q4Q1R3 | Leishmania major | 35% | 100% |
| Q4Q1R4 | Leishmania major | 39% | 100% |
| Q5R5R5 | Pongo abelii | 39% | 76% |
| Q8T8R1 | Drosophila melanogaster | 35% | 82% |
| Q8WW36 | Homo sapiens | 34% | 81% |
| V5BJZ6 | Trypanosoma cruzi | 47% | 70% |
| V5BU64 | Trypanosoma cruzi | 38% | 70% |
| V5BU71 | Trypanosoma cruzi | 37% | 100% |