Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDB5_LEIIN

TriTrypDb:

LINF_360020800

Length:

655

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDB5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDB5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	203	207	PF00656	0.692
CLV_C14_Caspase3-7	345	349	PF00656	0.723
CLV_C14_Caspase3-7	492	496	PF00656	0.590
CLV_MEL_PAP_1	564	570	PF00089	0.695
CLV_NRD_NRD_1	101	103	PF00675	0.675
CLV_NRD_NRD_1	249	251	PF00675	0.646
CLV_NRD_NRD_1	327	329	PF00675	0.803
CLV_NRD_NRD_1	425	427	PF00675	0.730
CLV_NRD_NRD_1	434	436	PF00675	0.643
CLV_NRD_NRD_1	482	484	PF00675	0.713
CLV_NRD_NRD_1	513	515	PF00675	0.734
CLV_NRD_NRD_1	52	54	PF00675	0.794
CLV_NRD_NRD_1	629	631	PF00675	0.592
CLV_NRD_NRD_1	647	649	PF00675	0.535
CLV_PCSK_FUR_1	99	103	PF00082	0.672
CLV_PCSK_KEX2_1	101	103	PF00082	0.675
CLV_PCSK_KEX2_1	249	251	PF00082	0.644
CLV_PCSK_KEX2_1	327	329	PF00082	0.803
CLV_PCSK_KEX2_1	425	427	PF00082	0.835
CLV_PCSK_KEX2_1	434	436	PF00082	0.701
CLV_PCSK_KEX2_1	482	484	PF00082	0.713
CLV_PCSK_KEX2_1	513	515	PF00082	0.734
CLV_PCSK_KEX2_1	52	54	PF00082	0.792
CLV_PCSK_KEX2_1	629	631	PF00082	0.596
CLV_PCSK_KEX2_1	646	648	PF00082	0.542
CLV_PCSK_PC7_1	48	54	PF00082	0.606
CLV_PCSK_PC7_1	642	648	PF00082	0.692
CLV_PCSK_SKI1_1	211	215	PF00082	0.717
CLV_PCSK_SKI1_1	327	331	PF00082	0.797
CLV_PCSK_SKI1_1	457	461	PF00082	0.707
CLV_PCSK_SKI1_1	513	517	PF00082	0.732
DEG_APCC_DBOX_1	392	400	PF00400	0.695
DEG_COP1_1	481	490	PF00400	0.583
DEG_Nend_Nbox_1	1	3	PF02207	0.529
DEG_SCF_FBW7_2	458	465	PF00400	0.680
DEG_SPOP_SBC_1	252	256	PF00917	0.827
DEG_SPOP_SBC_1	409	413	PF00917	0.789
DEG_SPOP_SBC_1	518	522	PF00917	0.718
DEG_SPOP_SBC_1	78	82	PF00917	0.720
DOC_CDC14_PxL_1	363	371	PF14671	0.604
DOC_CKS1_1	459	464	PF01111	0.706
DOC_CYCLIN_RxL_1	324	334	PF00134	0.794
DOC_MAPK_RevD_3	87	102	PF00069	0.649
DOC_PP1_RVXF_1	58	65	PF00149	0.781
DOC_PP2B_LxvP_1	369	372	PF13499	0.595
DOC_PP4_FxxP_1	150	153	PF00568	0.686
DOC_PP4_FxxP_1	29	32	PF00568	0.824
DOC_PP4_FxxP_1	485	488	PF00568	0.671
DOC_PP4_FxxP_1	64	67	PF00568	0.776
DOC_USP7_MATH_1	112	116	PF00917	0.490
DOC_USP7_MATH_1	174	178	PF00917	0.756
DOC_USP7_MATH_1	213	217	PF00917	0.769
DOC_USP7_MATH_1	224	228	PF00917	0.684
DOC_USP7_MATH_1	301	305	PF00917	0.686
DOC_USP7_MATH_1	310	314	PF00917	0.651
DOC_USP7_MATH_1	33	37	PF00917	0.742
DOC_USP7_MATH_1	372	376	PF00917	0.716
DOC_USP7_MATH_1	409	413	PF00917	0.752
DOC_USP7_MATH_1	417	421	PF00917	0.742
DOC_USP7_MATH_1	463	467	PF00917	0.643
DOC_USP7_MATH_1	572	576	PF00917	0.775
DOC_USP7_MATH_1	579	583	PF00917	0.622
DOC_USP7_MATH_1	97	101	PF00917	0.596
DOC_WW_Pin1_4	163	168	PF00397	0.838
DOC_WW_Pin1_4	217	222	PF00397	0.737
DOC_WW_Pin1_4	263	268	PF00397	0.748
DOC_WW_Pin1_4	278	283	PF00397	0.662
DOC_WW_Pin1_4	338	343	PF00397	0.808
DOC_WW_Pin1_4	351	356	PF00397	0.632
DOC_WW_Pin1_4	361	366	PF00397	0.627
DOC_WW_Pin1_4	387	392	PF00397	0.845
DOC_WW_Pin1_4	437	442	PF00397	0.624
DOC_WW_Pin1_4	458	463	PF00397	0.693
DOC_WW_Pin1_4	466	471	PF00397	0.655
DOC_WW_Pin1_4	493	498	PF00397	0.755
DOC_WW_Pin1_4	551	556	PF00397	0.622
DOC_WW_Pin1_4	568	573	PF00397	0.645
LIG_14-3-3_CanoR_1	162	167	PF00244	0.692
LIG_14-3-3_CanoR_1	211	221	PF00244	0.827
LIG_14-3-3_CanoR_1	244	252	PF00244	0.790
LIG_14-3-3_CanoR_1	434	441	PF00244	0.746
LIG_14-3-3_CanoR_1	457	462	PF00244	0.671
LIG_14-3-3_CanoR_1	567	572	PF00244	0.783
LIG_14-3-3_CanoR_1	574	584	PF00244	0.708
LIG_14-3-3_CanoR_1	629	638	PF00244	0.445
LIG_BRCT_BRCA1_1	272	276	PF00533	0.673
LIG_BRCT_BRCA1_1	542	546	PF00533	0.706
LIG_deltaCOP1_diTrp_1	475	485	PF00928	0.655
LIG_EVH1_1	150	154	PF00568	0.686
LIG_FHA_1	253	259	PF00498	0.726
LIG_FHA_1	444	450	PF00498	0.684
LIG_FHA_1	563	569	PF00498	0.751
LIG_FHA_1	588	594	PF00498	0.701
LIG_FHA_2	201	207	PF00498	0.697
LIG_FHA_2	343	349	PF00498	0.756
LIG_FHA_2	351	357	PF00498	0.717
LIG_FHA_2	514	520	PF00498	0.705
LIG_FHA_2	618	624	PF00498	0.646
LIG_Integrin_RGD_1	48	50	PF01839	0.611
LIG_LIR_Apic_2	149	153	PF02991	0.690
LIG_LIR_Apic_2	27	32	PF02991	0.663
LIG_LIR_Apic_2	336	342	PF02991	0.799
LIG_LIR_Apic_2	484	488	PF02991	0.667
LIG_LIR_Gen_1	586	594	PF02991	0.603
LIG_LIR_Nem_3	314	320	PF02991	0.747
LIG_LIR_Nem_3	586	592	PF02991	0.705
LIG_LIR_Nem_3	599	604	PF02991	0.621
LIG_MYND_1	367	371	PF01753	0.597
LIG_PDZ_Class_1	650	655	PF00595	0.799
LIG_PROFILIN_1	151	157	PF00235	0.536
LIG_RPA_C_Fungi	96	108	PF08784	0.610
LIG_SH2_CRK	317	321	PF00017	0.671
LIG_SH2_CRK	589	593	PF00017	0.536
LIG_SH2_PTP2	339	342	PF00017	0.772
LIG_SH2_STAP1	589	593	PF00017	0.571
LIG_SH2_STAT5	339	342	PF00017	0.805
LIG_SH2_STAT5	589	592	PF00017	0.532
LIG_SH3_2	157	162	PF14604	0.637
LIG_SH3_3	119	125	PF00018	0.632
LIG_SH3_3	135	141	PF00018	0.668
LIG_SH3_3	145	151	PF00018	0.651
LIG_SH3_3	154	160	PF00018	0.534
LIG_SH3_3	445	451	PF00018	0.722
LIG_SUMO_SIM_par_1	126	132	PF11976	0.725
LIG_SUMO_SIM_par_1	87	92	PF11976	0.714
LIG_TRAF2_1	611	614	PF00917	0.534
LIG_TRAF2_2	45	50	PF00917	0.759
LIG_TYR_ITIM	315	320	PF00017	0.679
LIG_WRC_WIRS_1	402	407	PF05994	0.602
LIG_WW_3	461	465	PF00397	0.713
MOD_CDC14_SPxK_1	554	557	PF00782	0.566
MOD_CDC14_SPxK_1	571	574	PF00782	0.524
MOD_CDK_SPxK_1	387	393	PF00069	0.762
MOD_CDK_SPxK_1	458	464	PF00069	0.706
MOD_CDK_SPxK_1	551	557	PF00069	0.565
MOD_CDK_SPxK_1	568	574	PF00069	0.523
MOD_CK1_1	115	121	PF00069	0.723
MOD_CK1_1	225	231	PF00069	0.767
MOD_CK1_1	253	259	PF00069	0.831
MOD_CK1_1	281	287	PF00069	0.666
MOD_CK1_1	385	391	PF00069	0.840
MOD_CK1_1	411	417	PF00069	0.763
MOD_CK1_1	440	446	PF00069	0.756
MOD_CK1_1	466	472	PF00069	0.688
MOD_CK1_1	478	484	PF00069	0.645
MOD_CK1_1	489	495	PF00069	0.662
MOD_CK1_1	496	502	PF00069	0.583
MOD_CK1_1	517	523	PF00069	0.823
MOD_CK1_1	541	547	PF00069	0.796
MOD_CK1_1	55	61	PF00069	0.715
MOD_CK1_1	570	576	PF00069	0.726
MOD_CK1_1	582	588	PF00069	0.560
MOD_CK1_1	636	642	PF00069	0.587
MOD_CK2_1	213	219	PF00069	0.820
MOD_CK2_1	305	311	PF00069	0.824
MOD_CK2_1	350	356	PF00069	0.849
MOD_CK2_1	386	392	PF00069	0.691
MOD_CK2_1	395	401	PF00069	0.686
MOD_CK2_1	513	519	PF00069	0.708
MOD_CK2_1	531	537	PF00069	0.501
MOD_CK2_1	608	614	PF00069	0.736
MOD_CK2_1	617	623	PF00069	0.654
MOD_CK2_1	68	74	PF00069	0.614
MOD_DYRK1A_RPxSP_1	217	221	PF00069	0.649
MOD_GlcNHglycan	117	120	PF01048	0.728
MOD_GlcNHglycan	14	18	PF01048	0.653
MOD_GlcNHglycan	170	173	PF01048	0.733
MOD_GlcNHglycan	176	179	PF01048	0.722
MOD_GlcNHglycan	227	230	PF01048	0.820
MOD_GlcNHglycan	255	258	PF01048	0.701
MOD_GlcNHglycan	307	310	PF01048	0.710
MOD_GlcNHglycan	35	38	PF01048	0.710
MOD_GlcNHglycan	374	377	PF01048	0.676
MOD_GlcNHglycan	516	519	PF01048	0.804
MOD_GlcNHglycan	527	530	PF01048	0.622
MOD_GlcNHglycan	534	537	PF01048	0.507
MOD_GlcNHglycan	54	57	PF01048	0.499
MOD_GlcNHglycan	543	546	PF01048	0.569
MOD_GlcNHglycan	577	580	PF01048	0.771
MOD_GlcNHglycan	585	588	PF01048	0.669
MOD_GlcNHglycan	613	617	PF01048	0.713
MOD_GlcNHglycan	82	85	PF01048	0.752
MOD_GSK3_1	158	165	PF00069	0.819
MOD_GSK3_1	207	214	PF00069	0.844
MOD_GSK3_1	253	260	PF00069	0.799
MOD_GSK3_1	270	277	PF00069	0.530
MOD_GSK3_1	301	308	PF00069	0.661
MOD_GSK3_1	334	341	PF00069	0.774
MOD_GSK3_1	382	389	PF00069	0.824
MOD_GSK3_1	39	46	PF00069	0.818
MOD_GSK3_1	401	408	PF00069	0.518
MOD_GSK3_1	411	418	PF00069	0.615
MOD_GSK3_1	429	436	PF00069	0.580
MOD_GSK3_1	437	444	PF00069	0.716
MOD_GSK3_1	471	478	PF00069	0.694
MOD_GSK3_1	489	496	PF00069	0.533
MOD_GSK3_1	499	506	PF00069	0.705
MOD_GSK3_1	513	520	PF00069	0.610
MOD_GSK3_1	521	528	PF00069	0.659
MOD_GSK3_1	537	544	PF00069	0.630
MOD_GSK3_1	562	569	PF00069	0.789
MOD_GSK3_1	575	582	PF00069	0.622
MOD_GSK3_1	583	590	PF00069	0.562
MOD_GSK3_1	592	599	PF00069	0.553
MOD_GSK3_1	605	612	PF00069	0.548
MOD_GSK3_1	629	636	PF00069	0.539
MOD_N-GLC_1	320	325	PF02516	0.687
MOD_N-GLC_1	331	336	PF02516	0.561
MOD_N-GLC_1	386	391	PF02516	0.618
MOD_NEK2_1	1	6	PF00069	0.617
MOD_NEK2_1	143	148	PF00069	0.699
MOD_NEK2_1	433	438	PF00069	0.748
MOD_NEK2_1	531	536	PF00069	0.706
MOD_NEK2_1	583	588	PF00069	0.759
MOD_NEK2_1	592	597	PF00069	0.654
MOD_PIKK_1	244	250	PF00454	0.711
MOD_PIKK_1	320	326	PF00454	0.740
MOD_PIKK_1	43	49	PF00454	0.781
MOD_PIKK_1	499	505	PF00454	0.734
MOD_PKA_1	434	440	PF00069	0.643
MOD_PKA_1	513	519	PF00069	0.729
MOD_PKA_1	52	58	PF00069	0.786
MOD_PKA_1	629	635	PF00069	0.586
MOD_PKA_2	161	167	PF00069	0.692
MOD_PKA_2	207	213	PF00069	0.687
MOD_PKA_2	350	356	PF00069	0.807
MOD_PKA_2	433	439	PF00069	0.715
MOD_PKA_2	463	469	PF00069	0.707
MOD_PKA_2	513	519	PF00069	0.722
MOD_PKA_2	52	58	PF00069	0.658
MOD_PKA_2	531	537	PF00069	0.544
MOD_PKA_2	566	572	PF00069	0.759
MOD_PKA_2	579	585	PF00069	0.653
MOD_PKA_2	617	623	PF00069	0.656
MOD_PKA_2	629	635	PF00069	0.537
MOD_PKB_1	393	401	PF00069	0.603
MOD_PKB_1	530	538	PF00069	0.692
MOD_Plk_1	199	205	PF00069	0.722
MOD_Plk_1	310	316	PF00069	0.696
MOD_Plk_1	475	481	PF00069	0.780
MOD_Plk_1	507	513	PF00069	0.731
MOD_Plk_1	538	544	PF00069	0.812
MOD_Plk_1	605	611	PF00069	0.644
MOD_Plk_1	7	13	PF00069	0.728
MOD_Plk_2-3	200	206	PF00069	0.636
MOD_Plk_2-3	617	623	PF00069	0.708
MOD_Plk_4	112	118	PF00069	0.546
MOD_Plk_4	334	340	PF00069	0.795
MOD_Plk_4	395	401	PF00069	0.792
MOD_Plk_4	579	585	PF00069	0.781
MOD_ProDKin_1	163	169	PF00069	0.836
MOD_ProDKin_1	217	223	PF00069	0.736
MOD_ProDKin_1	263	269	PF00069	0.746
MOD_ProDKin_1	278	284	PF00069	0.661
MOD_ProDKin_1	338	344	PF00069	0.810
MOD_ProDKin_1	351	357	PF00069	0.634
MOD_ProDKin_1	361	367	PF00069	0.623
MOD_ProDKin_1	387	393	PF00069	0.846
MOD_ProDKin_1	437	443	PF00069	0.622
MOD_ProDKin_1	458	464	PF00069	0.698
MOD_ProDKin_1	466	472	PF00069	0.654
MOD_ProDKin_1	493	499	PF00069	0.758
MOD_ProDKin_1	551	557	PF00069	0.624
MOD_ProDKin_1	568	574	PF00069	0.646
MOD_SUMO_for_1	295	298	PF00179	0.639
MOD_SUMO_for_1	634	637	PF00179	0.674
MOD_SUMO_rev_2	469	478	PF00179	0.687
TRG_DiLeu_BaEn_2	400	406	PF01217	0.603
TRG_DiLeu_BaLyEn_6	454	459	PF01217	0.709
TRG_ENDOCYTIC_2	317	320	PF00928	0.778
TRG_ENDOCYTIC_2	589	592	PF00928	0.712
TRG_ENDOCYTIC_2	601	604	PF00928	0.636
TRG_ER_diArg_1	249	251	PF00400	0.644
TRG_ER_diArg_1	327	329	PF00400	0.803
TRG_ER_diArg_1	393	396	PF00400	0.616
TRG_ER_diArg_1	424	426	PF00400	0.722
TRG_ER_diArg_1	433	435	PF00400	0.651
TRG_ER_diArg_1	51	53	PF00400	0.728
TRG_ER_diArg_1	512	514	PF00400	0.731
TRG_ER_diArg_1	556	559	PF00400	0.700
TRG_ER_diArg_1	629	631	PF00400	0.622
TRG_ER_diArg_1	640	643	PF00400	0.577
TRG_ER_diArg_1	646	648	PF00400	0.516
TRG_ER_diArg_1	98	101	PF00400	0.669
TRG_Pf-PMV_PEXEL_1	101	106	PF00026	0.682

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IK06	Leishmania donovani	98%	100%
A4HP06	Leishmania braziliensis	48%	100%
A4HP26	Leishmania braziliensis	47%	100%
E9ASR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4Q1T0	Leishmania major	82%	100%