Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IDA2_LEIIN

TriTrypDb:

LINF_360039600

Length:

249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IDA2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IDA2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.675
CLV_PCSK_KEX2_1	119	121	PF00082	0.644
CLV_PCSK_KEX2_1	73	75	PF00082	0.466
CLV_PCSK_PC1ET2_1	73	75	PF00082	0.538
CLV_PCSK_SKI1_1	11	15	PF00082	0.586
CLV_PCSK_SKI1_1	206	210	PF00082	0.549
DEG_SPOP_SBC_1	25	29	PF00917	0.630
DOC_MAPK_JIP1_4	37	43	PF00069	0.481
DOC_USP7_MATH_1	79	83	PF00917	0.615
DOC_USP7_MATH_1	9	13	PF00917	0.527
DOC_USP7_MATH_1	96	100	PF00917	0.605
DOC_WW_Pin1_4	161	166	PF00397	0.498
DOC_WW_Pin1_4	97	102	PF00397	0.566
LIG_14-3-3_CanoR_1	111	117	PF00244	0.507
LIG_14-3-3_CanoR_1	179	188	PF00244	0.479
LIG_14-3-3_CanoR_1	37	42	PF00244	0.677
LIG_14-3-3_CanoR_1	44	52	PF00244	0.500
LIG_14-3-3_CanoR_1	60	68	PF00244	0.623
LIG_BIR_II_1	1	5	PF00653	0.594
LIG_BIR_III_2	162	166	PF00653	0.546
LIG_BRCT_BRCA1_1	135	139	PF00533	0.751
LIG_BRCT_BRCA1_1	163	167	PF00533	0.497
LIG_BRCT_BRCA1_1	39	43	PF00533	0.596
LIG_deltaCOP1_diTrp_1	201	205	PF00928	0.463
LIG_deltaCOP1_diTrp_1	211	217	PF00928	0.423
LIG_FHA_1	108	114	PF00498	0.550
LIG_FHA_1	150	156	PF00498	0.578
LIG_FHA_2	171	177	PF00498	0.504
LIG_FHA_2	234	240	PF00498	0.592
LIG_LIR_Gen_1	211	219	PF02991	0.505
LIG_LIR_Gen_1	64	75	PF02991	0.432
LIG_LIR_Nem_3	136	142	PF02991	0.629
LIG_LIR_Nem_3	164	170	PF02991	0.497
LIG_LIR_Nem_3	203	208	PF02991	0.516
LIG_LIR_Nem_3	211	217	PF02991	0.517
LIG_LIR_Nem_3	64	70	PF02991	0.430
LIG_MYND_1	241	245	PF01753	0.325
LIG_PDZ_Class_3	244	249	PF00595	0.556
LIG_SH2_PTP2	67	70	PF00017	0.394
LIG_SH2_STAP1	170	174	PF00017	0.460
LIG_SH2_STAT5	116	119	PF00017	0.567
LIG_SH2_STAT5	199	202	PF00017	0.550
LIG_SH2_STAT5	67	70	PF00017	0.394
LIG_SH3_3	162	168	PF00018	0.535
LIG_SH3_3	99	105	PF00018	0.556
LIG_SUMO_SIM_anti_2	66	72	PF11976	0.471
LIG_SUMO_SIM_par_1	145	153	PF11976	0.588
LIG_TRAF2_1	236	239	PF00917	0.427
MOD_CK1_1	100	106	PF00069	0.645
MOD_CK1_1	107	113	PF00069	0.653
MOD_CK1_1	134	140	PF00069	0.564
MOD_CK1_1	29	35	PF00069	0.653
MOD_CK1_1	3	9	PF00069	0.633
MOD_CK1_1	42	48	PF00069	0.534
MOD_CK2_1	170	176	PF00069	0.495
MOD_CK2_1	215	221	PF00069	0.422
MOD_CK2_1	232	238	PF00069	0.369
MOD_CK2_1	42	48	PF00069	0.468
MOD_CMANNOS	202	205	PF00535	0.454
MOD_GlcNHglycan	102	105	PF01048	0.550
MOD_GlcNHglycan	217	220	PF01048	0.482
MOD_GlcNHglycan	44	47	PF01048	0.616
MOD_GlcNHglycan	75	78	PF01048	0.623
MOD_GSK3_1	127	134	PF00069	0.642
MOD_GSK3_1	24	31	PF00069	0.693
MOD_GSK3_1	59	66	PF00069	0.668
MOD_GSK3_1	96	103	PF00069	0.630
MOD_NEK2_1	112	117	PF00069	0.529
MOD_NEK2_1	149	154	PF00069	0.627
MOD_NEK2_1	232	237	PF00069	0.430
MOD_NEK2_2	79	84	PF00069	0.486
MOD_PIKK_1	134	140	PF00454	0.646
MOD_PIKK_1	3	9	PF00454	0.548
MOD_PKA_1	73	79	PF00069	0.487
MOD_PKA_2	36	42	PF00069	0.692
MOD_PKA_2	59	65	PF00069	0.685
MOD_PKA_2	73	79	PF00069	0.421
MOD_PKB_1	22	30	PF00069	0.488
MOD_Plk_4	112	118	PF00069	0.533
MOD_Plk_4	63	69	PF00069	0.504
MOD_Plk_4	9	15	PF00069	0.587
MOD_ProDKin_1	161	167	PF00069	0.496
MOD_ProDKin_1	97	103	PF00069	0.562
TRG_DiLeu_BaEn_4	238	244	PF01217	0.416
TRG_DiLeu_BaLyEn_6	108	113	PF01217	0.546
TRG_DiLeu_BaLyEn_6	144	149	PF01217	0.582
TRG_DiLeu_BaLyEn_6	223	228	PF01217	0.458
TRG_ENDOCYTIC_2	67	70	PF00928	0.394
TRG_ER_diArg_1	21	24	PF00400	0.484
TRG_NLS_MonoExtN_4	105	112	PF00514	0.589
TRG_Pf-PMV_PEXEL_1	226	230	PF00026	0.489

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1D7	Leptomonas seymouri	48%	100%
A0A3Q8IW55	Leishmania donovani	100%	100%
A0A3R7NG27	Trypanosoma rangeli	32%	100%
A4HPI0	Leishmania braziliensis	81%	100%
E9AT92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q1A5	Leishmania major	92%	100%
V5DA52	Trypanosoma cruzi	28%	100%