RNA Processing, Fibrillarin
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 9 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 20 |
| NetGPI | no | yes: 0, no: 20 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005730 | nucleolus | 5 | 2 |
| GO:0005732 | sno(s)RNA-containing ribonucleoprotein complex | 3 | 2 |
| GO:0030684 | preribosome | 3 | 2 |
| GO:0031428 | box C/D RNP complex | 4 | 2 |
| GO:0032040 | small-subunit processome | 4 | 2 |
| GO:0032991 | protein-containing complex | 1 | 2 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 2 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 2 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:1990904 | ribonucleoprotein complex | 2 | 2 |
| GO:0005634 | nucleus | 5 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4ID95
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006139 | nucleobase-containing compound metabolic process | 3 | 21 |
| GO:0006364 | rRNA processing | 8 | 21 |
| GO:0006396 | RNA processing | 6 | 21 |
| GO:0006725 | cellular aromatic compound metabolic process | 3 | 21 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 21 |
| GO:0008152 | metabolic process | 1 | 21 |
| GO:0009987 | cellular process | 1 | 21 |
| GO:0016070 | RNA metabolic process | 5 | 21 |
| GO:0016072 | rRNA metabolic process | 7 | 21 |
| GO:0032259 | methylation | 2 | 21 |
| GO:0034470 | ncRNA processing | 7 | 21 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 21 |
| GO:0034660 | ncRNA metabolic process | 6 | 21 |
| GO:0043170 | macromolecule metabolic process | 3 | 21 |
| GO:0044237 | cellular metabolic process | 2 | 21 |
| GO:0044238 | primary metabolic process | 2 | 21 |
| GO:0046483 | heterocycle metabolic process | 3 | 21 |
| GO:0071704 | organic substance metabolic process | 2 | 21 |
| GO:0090304 | nucleic acid metabolic process | 4 | 21 |
| GO:1901360 | organic cyclic compound metabolic process | 3 | 21 |
| GO:0000154 | rRNA modification | 6 | 2 |
| GO:0000494 | box C/D RNA 3'-end processing | 10 | 2 |
| GO:0001510 | RNA methylation | 4 | 2 |
| GO:0006479 | protein methylation | 4 | 2 |
| GO:0008213 | protein alkylation | 5 | 2 |
| GO:0009451 | RNA modification | 5 | 2 |
| GO:0016074 | sno(s)RNA metabolic process | 7 | 2 |
| GO:0016570 | histone modification | 5 | 2 |
| GO:0016571 | histone methylation | 5 | 2 |
| GO:0018364 | peptidyl-glutamine methylation | 5 | 2 |
| GO:0019538 | protein metabolic process | 3 | 2 |
| GO:0031123 | RNA 3'-end processing | 7 | 2 |
| GO:0031126 | sno(s)RNA 3'-end processing | 9 | 2 |
| GO:0031167 | rRNA methylation | 5 | 2 |
| GO:0033967 | box C/D RNA metabolic process | 8 | 2 |
| GO:0034963 | box C/D RNA processing | 9 | 2 |
| GO:0036211 | protein modification process | 4 | 2 |
| GO:0043144 | sno(s)RNA processing | 8 | 2 |
| GO:0043412 | macromolecule modification | 4 | 2 |
| GO:0043414 | macromolecule methylation | 3 | 2 |
| GO:0043628 | regulatory ncRNA 3'-end processing | 8 | 2 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 2 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 2 |
| GO:1990258 | histone glutamine methylation | 6 | 2 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 21 |
| GO:0003723 | RNA binding | 4 | 21 |
| GO:0003824 | catalytic activity | 1 | 21 |
| GO:0005488 | binding | 1 | 21 |
| GO:0008168 | methyltransferase activity | 4 | 21 |
| GO:0016740 | transferase activity | 2 | 21 |
| GO:0016741 | transferase activity, transferring one-carbon groups | 3 | 21 |
| GO:0097159 | organic cyclic compound binding | 2 | 21 |
| GO:1901363 | heterocyclic compound binding | 2 | 21 |
| GO:0008170 | N-methyltransferase activity | 5 | 2 |
| GO:0008173 | RNA methyltransferase activity | 4 | 2 |
| GO:0008276 | protein methyltransferase activity | 3 | 2 |
| GO:0008649 | rRNA methyltransferase activity | 5 | 2 |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | 5 | 2 |
| GO:0036009 | protein-glutamine N-methyltransferase activity | 4 | 2 |
| GO:0042054 | histone methyltransferase activity | 4 | 2 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 2 |
| GO:0140098 | catalytic activity, acting on RNA | 3 | 2 |
| GO:0140102 | catalytic activity, acting on a rRNA | 4 | 2 |
| GO:0140640 | catalytic activity, acting on a nucleic acid | 2 | 2 |
| GO:1990259 | histone H2AQ104 methyltransferase activity | 5 | 2 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 119 | 121 | PF00675 | 0.200 |
| CLV_PCSK_KEX2_1 | 118 | 120 | PF00082 | 0.200 |
| CLV_PCSK_KEX2_1 | 31 | 33 | PF00082 | 0.200 |
| CLV_PCSK_PC1ET2_1 | 118 | 120 | PF00082 | 0.200 |
| CLV_PCSK_PC1ET2_1 | 31 | 33 | PF00082 | 0.200 |
| CLV_PCSK_SKI1_1 | 227 | 231 | PF00082 | 0.331 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.304 |
| DOC_CYCLIN_yCln2_LP_2 | 186 | 192 | PF00134 | 0.196 |
| DOC_MAPK_gen_1 | 118 | 126 | PF00069 | 0.200 |
| DOC_MAPK_gen_1 | 203 | 212 | PF00069 | 0.334 |
| DOC_MAPK_MEF2A_6 | 135 | 142 | PF00069 | 0.211 |
| DOC_MAPK_MEF2A_6 | 217 | 225 | PF00069 | 0.196 |
| DOC_PP2B_LxvP_1 | 186 | 189 | PF13499 | 0.196 |
| DOC_PP2B_PxIxI_1 | 22 | 28 | PF00149 | 0.290 |
| DOC_USP7_MATH_1 | 52 | 56 | PF00917 | 0.185 |
| DOC_USP7_MATH_1 | 63 | 67 | PF00917 | 0.200 |
| DOC_USP7_MATH_2 | 206 | 212 | PF00917 | 0.208 |
| DOC_USP7_UBL2_3 | 201 | 205 | PF12436 | 0.196 |
| LIG_APCC_ABBA_1 | 25 | 30 | PF00400 | 0.200 |
| LIG_FHA_1 | 11 | 17 | PF00498 | 0.178 |
| LIG_IBAR_NPY_1 | 51 | 53 | PF08397 | 0.200 |
| LIG_LIR_Gen_1 | 144 | 153 | PF02991 | 0.200 |
| LIG_LIR_Nem_3 | 144 | 150 | PF02991 | 0.200 |
| LIG_LIR_Nem_3 | 59 | 65 | PF02991 | 0.352 |
| LIG_SH2_CRK | 136 | 140 | PF00017 | 0.200 |
| LIG_SH2_CRK | 226 | 230 | PF00017 | 0.351 |
| LIG_SH2_CRK | 62 | 66 | PF00017 | 0.208 |
| LIG_SH2_SRC | 173 | 176 | PF00017 | 0.196 |
| LIG_SH2_STAP1 | 101 | 105 | PF00017 | 0.200 |
| LIG_SH2_STAT5 | 173 | 176 | PF00017 | 0.242 |
| LIG_SH2_STAT5 | 78 | 81 | PF00017 | 0.209 |
| LIG_SH3_3 | 147 | 153 | PF00018 | 0.200 |
| LIG_SH3_3 | 222 | 228 | PF00018 | 0.178 |
| LIG_SH3_4 | 205 | 212 | PF00018 | 0.196 |
| LIG_SUMO_SIM_par_1 | 187 | 195 | PF11976 | 0.254 |
| MOD_CK1_1 | 15 | 21 | PF00069 | 0.264 |
| MOD_CK1_1 | 88 | 94 | PF00069 | 0.210 |
| MOD_CK2_1 | 181 | 187 | PF00069 | 0.188 |
| MOD_GlcNHglycan | 58 | 61 | PF01048 | 0.291 |
| MOD_GSK3_1 | 52 | 59 | PF00069 | 0.337 |
| MOD_GSK3_1 | 6 | 13 | PF00069 | 0.375 |
| MOD_NEK2_1 | 35 | 40 | PF00069 | 0.232 |
| MOD_NEK2_2 | 173 | 178 | PF00069 | 0.220 |
| MOD_NEK2_2 | 23 | 28 | PF00069 | 0.200 |
| MOD_NEK2_2 | 64 | 69 | PF00069 | 0.252 |
| MOD_PIKK_1 | 35 | 41 | PF00454 | 0.211 |
| MOD_Plk_1 | 182 | 188 | PF00069 | 0.196 |
| MOD_Plk_2-3 | 208 | 214 | PF00069 | 0.200 |
| TRG_ENDOCYTIC_2 | 136 | 139 | PF00928 | 0.200 |
| TRG_ENDOCYTIC_2 | 226 | 229 | PF00928 | 0.343 |
| TRG_ENDOCYTIC_2 | 62 | 65 | PF00928 | 0.200 |
| TRG_ER_diArg_1 | 119 | 121 | PF00400 | 0.174 |
| TRG_ER_diLys_1 | 230 | 234 | PF00400 | 0.419 |
| TRG_NES_CRM1_1 | 202 | 216 | PF08389 | 0.334 |
| TRG_NLS_MonoExtN_4 | 227 | 234 | PF00514 | 0.321 |
| TRG_Pf-PMV_PEXEL_1 | 111 | 115 | PF00026 | 0.213 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7A3 | Leptomonas seymouri | 97% | 76% |
| A0A0N1PA75 | Leptomonas seymouri | 67% | 78% |
| A0A0S4IYN2 | Bodo saltans | 65% | 76% |
| A0A0S4J8H3 | Bodo saltans | 89% | 79% |
| A0A1X0NKM9 | Trypanosomatidae | 93% | 77% |
| A0A1X0P6R0 | Trypanosomatidae | 71% | 76% |
| A0A3Q8ID71 | Leishmania donovani | 68% | 78% |
| A0A3S5H830 | Leishmania donovani | 100% | 77% |
| A0A422NCX2 | Trypanosoma rangeli | 71% | 81% |
| A0A422NM05 | Trypanosoma rangeli | 93% | 79% |
| A0B6X7 | Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) | 42% | 100% |
| A1RRJ7 | Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) | 46% | 100% |
| A3CSX5 | Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) | 41% | 100% |
| A3DNY7 | Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) | 45% | 100% |
| A3MV65 | Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) | 45% | 100% |
| A4FYN1 | Methanococcus maripaludis (strain C5 / ATCC BAA-1333) | 41% | 100% |
| A4HPH3 | Leishmania braziliensis | 99% | 100% |
| A4WKL2 | Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6) | 46% | 100% |
| A6NHQ2 | Homo sapiens | 68% | 70% |
| A6UV22 | Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3) | 43% | 100% |
| A6VJQ1 | Methanococcus maripaludis (strain C7 / ATCC BAA-1331) | 40% | 100% |
| A9A6C8 | Methanococcus maripaludis (strain C6 / ATCC BAA-1332) | 41% | 100% |
| B0R515 | Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) | 39% | 100% |
| B1YAJ6 | Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta) | 46% | 100% |
| B6YXH6 | Thermococcus onnurineus (strain NA1) | 50% | 100% |
| B9LMQ1 | Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) | 42% | 100% |
| C3MPR8 | Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) | 43% | 100% |
| C3MYR2 | Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) | 43% | 100% |
| C3N5E4 | Sulfolobus islandicus (strain M.16.27) | 43% | 100% |
| C3NDZ8 | Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) | 43% | 100% |
| C3NHQ5 | Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) | 43% | 100% |
| C4KH10 | Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) | 43% | 100% |
| C5A403 | Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) | 49% | 100% |
| C6A2L3 | Thermococcus sibiricus (strain DSM 12597 / MM 739) | 48% | 100% |
| D0A0B7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 72% | 100% |
| D0A0D0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 72% | 77% |
| D0A3I3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 88% | 78% |
| E9AGR2 | Leishmania infantum | 68% | 80% |
| E9ARW1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 71% | 100% |
| E9AT85 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 100% | 100% |
| O27283 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 42% | 100% |
| O28192 | Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) | 44% | 100% |
| O57811 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 47% | 100% |
| P0CW08 | Methanosarcina mazei | 47% | 100% |
| P0CW09 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 44% | 100% |
| P15646 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 63% | 72% |
| P22087 | Homo sapiens | 67% | 73% |
| P22232 | Xenopus laevis | 65% | 72% |
| P22509 | Rattus norvegicus | 67% | 72% |
| P35549 | Leishmania major | 99% | 79% |
| P35550 | Mus musculus | 67% | 72% |
| P35551 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 62% | 77% |
| P35552 | Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) | 42% | 100% |
| P35553 | Methanococcus voltae | 43% | 100% |
| P58032 | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | 43% | 100% |
| Q18H64 | Haloquadratum walsbyi (strain DSM 16790 / HBSQ001) | 36% | 100% |
| Q22053 | Caenorhabditis elegans | 69% | 66% |
| Q24957 | Giardia intestinalis | 56% | 72% |
| Q27200 | Tetrahymena thermophila | 64% | 80% |
| Q2FRP5 | Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) | 37% | 100% |
| Q46EB1 | Methanosarcina barkeri (strain Fusaro / DSM 804) | 45% | 100% |
| Q4Q1B2 | Leishmania major | 100% | 100% |
| Q4QDL1 | Leishmania major | 71% | 100% |
| Q55CW0 | Dictyostelium discoideum | 59% | 70% |
| Q58108 | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 42% | 100% |
| Q5JFN1 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 49% | 100% |
| Q5V3Q6 | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) | 40% | 100% |
| Q6BQ34 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 62% | 71% |
| Q6FN88 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 62% | 72% |
| Q6LZM7 | Methanococcus maripaludis (strain S2 / LL) | 41% | 100% |
| Q74N89 | Nanoarchaeum equitans (strain Kin4-M) | 42% | 100% |
| Q756P0 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 62% | 72% |
| Q80WS3 | Mus musculus | 68% | 75% |
| Q8I1F4 | Drosophila erecta | 69% | 68% |
| Q8SR42 | Encephalitozoon cuniculi (strain GB-M1) | 63% | 80% |
| Q8TTT4 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 43% | 100% |
| Q8TXU9 | Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) | 47% | 100% |
| Q8U4M2 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 47% | 100% |
| Q8ZTI9 | Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) | 47% | 100% |
| Q94AH9 | Arabidopsis thaliana | 68% | 73% |
| Q971W2 | Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) | 46% | 100% |
| Q979P2 | Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) | 34% | 100% |
| Q9FEF8 | Arabidopsis thaliana | 69% | 76% |
| Q9FHB3 | Arabidopsis thaliana | 56% | 80% |
| Q9HE26 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 61% | 72% |
| Q9HH35 | Methanothermobacter wolfeii | 43% | 100% |
| Q9HJL8 | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) | 37% | 100% |
| Q9HQG3 | Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) | 39% | 100% |
| Q9P9M0 | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) | 44% | 100% |
| Q9V2L5 | Pyrococcus abyssi (strain GE5 / Orsay) | 47% | 100% |
| Q9W1V3 | Drosophila melanogaster | 69% | 68% |
| Q9Y9U3 | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) | 45% | 100% |
| V5BFQ9 | Trypanosoma cruzi | 91% | 75% |
| V5BS95 | Trypanosoma cruzi | 71% | 82% |