Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ID65_LEIIN

TriTrypDb:

LINF_360041700

Length:

154

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

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Expansion

Sequence features

A4ID65

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID65

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	124	128	PF00656	0.483
CLV_NRD_NRD_1	3	5	PF00675	0.410
CLV_NRD_NRD_1	51	53	PF00675	0.411
CLV_PCSK_FUR_1	49	53	PF00082	0.405
CLV_PCSK_KEX2_1	3	5	PF00082	0.396
CLV_PCSK_KEX2_1	51	53	PF00082	0.411
CLV_PCSK_SKI1_1	111	115	PF00082	0.595
CLV_PCSK_SKI1_1	26	30	PF00082	0.346
CLV_PCSK_SKI1_1	54	58	PF00082	0.270
CLV_PCSK_SKI1_1	8	12	PF00082	0.403

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKX9	Leptomonas seymouri	61%	100%
A0A0S4IXN1	Bodo saltans	46%	100%
A0A1X0P3B6	Trypanosomatidae	58%	97%
A0A3Q8IL19	Leishmania donovani	99%	100%
A4HPJ9	Leishmania braziliensis	80%	100%
D0A8L5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	96%
E9ATB1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q186	Leishmania major	98%	100%

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