LeishMANIAdb
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NIPSNAP domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NIPSNAP domain-containing protein
Gene product:
NIPSNAP - putative
Species:
Leishmania infantum
UniProt:
A4ID51_LEIIN
TriTrypDb:
LINF_360043200
Length:
200

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0005739 mitochondrion 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4ID51
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID51

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 80 82 PF00675 0.301
DEG_Nend_Nbox_1 1 3 PF02207 0.460
DOC_CKS1_1 174 179 PF01111 0.506
DOC_MAPK_gen_1 165 175 PF00069 0.413
DOC_PP2B_PxIxI_1 45 51 PF00149 0.474
DOC_WW_Pin1_4 128 133 PF00397 0.370
DOC_WW_Pin1_4 173 178 PF00397 0.500
LIG_14-3-3_CanoR_1 190 196 PF00244 0.387
LIG_APCC_ABBA_1 130 135 PF00400 0.468
LIG_DCNL_PONY_1 1 4 PF03556 0.549
LIG_FHA_1 146 152 PF00498 0.420
LIG_FHA_1 174 180 PF00498 0.505
LIG_FHA_1 21 27 PF00498 0.508
LIG_FHA_1 54 60 PF00498 0.519
LIG_LIR_Apic_2 93 97 PF02991 0.521
LIG_LIR_Gen_1 148 153 PF02991 0.371
LIG_LIR_Gen_1 157 164 PF02991 0.307
LIG_LIR_Gen_1 29 39 PF02991 0.479
LIG_LIR_Nem_3 121 127 PF02991 0.432
LIG_LIR_Nem_3 148 152 PF02991 0.344
LIG_LIR_Nem_3 157 163 PF02991 0.325
LIG_LIR_Nem_3 29 34 PF02991 0.479
LIG_Pex14_1 90 94 PF04695 0.454
LIG_SH2_CRK 124 128 PF00017 0.392
LIG_SH2_GRB2like 71 74 PF00017 0.521
LIG_SH2_PTP2 160 163 PF00017 0.421
LIG_SH2_PTP2 65 68 PF00017 0.509
LIG_SH2_PTP2 94 97 PF00017 0.509
LIG_SH2_STAT3 126 129 PF00017 0.436
LIG_SH2_STAT3 41 44 PF00017 0.509
LIG_SH2_STAT5 126 129 PF00017 0.377
LIG_SH2_STAT5 160 163 PF00017 0.345
LIG_SH2_STAT5 24 27 PF00017 0.521
LIG_SH2_STAT5 65 68 PF00017 0.509
LIG_SH2_STAT5 94 97 PF00017 0.521
LIG_SH3_1 40 46 PF00018 0.521
LIG_SH3_3 171 177 PF00018 0.500
LIG_SH3_3 22 28 PF00018 0.599
LIG_SH3_3 40 46 PF00018 0.399
LIG_WRC_WIRS_1 31 36 PF05994 0.385
MOD_CDC14_SPxK_1 131 134 PF00782 0.469
MOD_CDK_SPxK_1 128 134 PF00069 0.396
MOD_CK1_1 120 126 PF00069 0.415
MOD_CK1_1 139 145 PF00069 0.342
MOD_GlcNHglycan 13 16 PF01048 0.555
MOD_GlcNHglycan 137 141 PF01048 0.508
MOD_GSK3_1 101 108 PF00069 0.457
MOD_GSK3_1 175 182 PF00069 0.493
MOD_N-GLC_1 117 122 PF02516 0.464
MOD_NEK2_1 101 106 PF00069 0.367
MOD_NEK2_1 145 150 PF00069 0.337
MOD_NEK2_1 179 184 PF00069 0.466
MOD_PIKK_1 118 124 PF00454 0.604
MOD_PKA_2 189 195 PF00069 0.363
MOD_Plk_4 105 111 PF00069 0.431
MOD_ProDKin_1 128 134 PF00069 0.375
MOD_ProDKin_1 173 179 PF00069 0.502
MOD_SUMO_rev_2 155 161 PF00179 0.406
TRG_ENDOCYTIC_2 124 127 PF00928 0.396
TRG_ENDOCYTIC_2 160 163 PF00928 0.345
TRG_ENDOCYTIC_2 31 34 PF00928 0.314
TRG_ENDOCYTIC_2 65 68 PF00928 0.360
TRG_ENDOCYTIC_2 71 74 PF00928 0.418
TRG_ER_diArg_1 45 48 PF00400 0.307

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKX6 Leptomonas seymouri 72% 100%
A0A1X0P390 Trypanosomatidae 53% 100%
A0A3S7XB71 Leishmania donovani 99% 100%
A0A422NA85 Trypanosoma rangeli 50% 100%
A4HPL3 Leishmania braziliensis 94% 100%
E9ATC5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4Q172 Leishmania major 98% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS