Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ID46_LEIIN

TriTrypDb:

LINF_360043700

Length:

189

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ID46

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID46

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	86	88	PF00675	0.472
CLV_PCSK_KEX2_1	107	109	PF00082	0.531
CLV_PCSK_KEX2_1	134	136	PF00082	0.436
CLV_PCSK_KEX2_1	46	48	PF00082	0.437
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.531
CLV_PCSK_PC1ET2_1	134	136	PF00082	0.436
CLV_PCSK_PC1ET2_1	46	48	PF00082	0.437
DEG_Nend_Nbox_1	1	3	PF02207	0.615
DOC_MAPK_gen_1	134	142	PF00069	0.475
DOC_MAPK_MEF2A_6	134	142	PF00069	0.438
DOC_MAPK_NFAT4_5	135	143	PF00069	0.437
DOC_PIKK_1	67	75	PF02985	0.450
DOC_PP2B_LxvP_1	163	166	PF13499	0.615
DOC_PP2B_PxIxI_1	36	42	PF00149	0.446
DOC_USP7_MATH_1	148	152	PF00917	0.550
DOC_USP7_MATH_1	17	21	PF00917	0.610
DOC_USP7_UBL2_3	46	50	PF12436	0.475
DOC_WW_Pin1_4	154	159	PF00397	0.658
LIG_14-3-3_CanoR_1	135	139	PF00244	0.440
LIG_14-3-3_CanoR_1	53	59	PF00244	0.462
LIG_14-3-3_CanoR_1	97	103	PF00244	0.521
LIG_Actin_WH2_2	125	141	PF00022	0.436
LIG_EVH1_1	163	167	PF00568	0.599
LIG_FHA_1	158	164	PF00498	0.658
LIG_FHA_1	28	34	PF00498	0.666
LIG_FHA_1	53	59	PF00498	0.469
LIG_FHA_1	91	97	PF00498	0.557
LIG_FHA_2	30	36	PF00498	0.524
LIG_LIR_Nem_3	119	125	PF02991	0.502
LIG_PCNA_yPIPBox_3	108	122	PF02747	0.490
LIG_SH2_SRC	78	81	PF00017	0.414
LIG_SH2_STAT5	78	81	PF00017	0.550
LIG_SH3_1	161	167	PF00018	0.602
LIG_SH3_3	152	158	PF00018	0.620
LIG_SH3_3	159	165	PF00018	0.558
LIG_SUMO_SIM_par_1	29	36	PF11976	0.522
LIG_SUMO_SIM_par_1	78	85	PF11976	0.415
MOD_CDK_SPxxK_3	154	161	PF00069	0.540
MOD_CK1_1	157	163	PF00069	0.523
MOD_CK1_1	3	9	PF00069	0.646
MOD_CK1_1	81	87	PF00069	0.447
MOD_CK1_1	98	104	PF00069	0.416
MOD_CK2_1	29	35	PF00069	0.539
MOD_Cter_Amidation	105	108	PF01082	0.548
MOD_GlcNHglycan	117	121	PF01048	0.506
MOD_GlcNHglycan	19	22	PF01048	0.569
MOD_GSK3_1	1	8	PF00069	0.496
MOD_NEK2_1	1	6	PF00069	0.604
MOD_NEK2_1	42	47	PF00069	0.479
MOD_PIKK_1	179	185	PF00454	0.605
MOD_PKA_1	134	140	PF00069	0.440
MOD_PKA_2	134	140	PF00069	0.440
MOD_PKA_2	52	58	PF00069	0.460
MOD_PKA_2	98	104	PF00069	0.528
MOD_Plk_1	116	122	PF00069	0.508
MOD_Plk_2-3	90	96	PF00069	0.502
MOD_Plk_4	98	104	PF00069	0.528
MOD_ProDKin_1	154	160	PF00069	0.659
TRG_DiLeu_BaEn_4	67	73	PF01217	0.447
TRG_ER_diArg_1	96	99	PF00400	0.453

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P3J1	Trypanosomatidae	38%	100%
A0A3S7XB75	Leishmania donovani	100%	99%
A4HPL8	Leishmania braziliensis	70%	100%
E9ATD0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4Q167	Leishmania major	94%	100%