Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ID36_LEIIN

TriTrypDb:

LINF_360044900

Length:

296

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4ID36

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID36

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	17	21	PF00656	0.594
CLV_C14_Caspase3-7	252	256	PF00656	0.782
CLV_NRD_NRD_1	108	110	PF00675	0.482
CLV_NRD_NRD_1	113	115	PF00675	0.468
CLV_NRD_NRD_1	133	135	PF00675	0.456
CLV_NRD_NRD_1	166	168	PF00675	0.363
CLV_NRD_NRD_1	197	199	PF00675	0.579
CLV_NRD_NRD_1	246	248	PF00675	0.605
CLV_NRD_NRD_1	277	279	PF00675	0.580
CLV_PCSK_FUR_1	109	113	PF00082	0.444
CLV_PCSK_KEX2_1	111	113	PF00082	0.412
CLV_PCSK_KEX2_1	133	135	PF00082	0.456
CLV_PCSK_KEX2_1	166	168	PF00082	0.363
CLV_PCSK_KEX2_1	197	199	PF00082	0.579
CLV_PCSK_KEX2_1	246	248	PF00082	0.605
CLV_PCSK_KEX2_1	277	279	PF00082	0.580
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.396
CLV_PCSK_PC7_1	109	115	PF00082	0.382
CLV_PCSK_SKI1_1	113	117	PF00082	0.440
CLV_PCSK_SKI1_1	3	7	PF00082	0.751
DEG_SPOP_SBC_1	14	18	PF00917	0.546
DEG_SPOP_SBC_1	74	78	PF00917	0.522
DOC_MAPK_gen_1	133	140	PF00069	0.656
DOC_MAPK_HePTP_8	80	92	PF00069	0.435
DOC_MAPK_MEF2A_6	83	92	PF00069	0.435
DOC_PP4_FxxP_1	291	294	PF00568	0.700
DOC_USP7_MATH_1	182	186	PF00917	0.728
DOC_USP7_MATH_1	69	73	PF00917	0.610
DOC_USP7_MATH_1	81	85	PF00917	0.377
DOC_USP7_UBL2_3	116	120	PF12436	0.674
DOC_WW_Pin1_4	279	284	PF00397	0.849
DOC_WW_Pin1_4	63	68	PF00397	0.550
LIG_deltaCOP1_diTrp_1	230	238	PF00928	0.708
LIG_deltaCOP1_diTrp_1	40	47	PF00928	0.474
LIG_FHA_1	43	49	PF00498	0.519
LIG_FHA_1	75	81	PF00498	0.564
LIG_FHA_1	83	89	PF00498	0.362
LIG_FHA_2	15	21	PF00498	0.598
LIG_FHA_2	269	275	PF00498	0.847
LIG_LIR_Nem_3	254	260	PF02991	0.782
LIG_LYPXL_yS_3	260	263	PF13949	0.676
LIG_PCNA_yPIPBox_3	166	176	PF02747	0.722
LIG_SH2_CRK	286	290	PF00017	0.780
LIG_SH2_STAP1	213	217	PF00017	0.778
LIG_SH2_STAP1	286	290	PF00017	0.752
LIG_SH2_STAT5	106	109	PF00017	0.498
LIG_SH2_STAT5	268	271	PF00017	0.786
LIG_SH2_STAT5	57	60	PF00017	0.506
LIG_SH3_3	236	242	PF00018	0.835
LIG_SH3_3	277	283	PF00018	0.706
LIG_Sin3_3	91	98	PF02671	0.413
LIG_SUMO_SIM_anti_2	84	91	PF11976	0.435
LIG_TRAF2_1	115	118	PF00917	0.667
LIG_TRAF2_1	128	131	PF00917	0.531
LIG_WW_1	283	286	PF00397	0.788
MOD_CK1_1	177	183	PF00069	0.733
MOD_CK1_1	18	24	PF00069	0.510
MOD_CK1_1	187	193	PF00069	0.746
MOD_CK1_1	266	272	PF00069	0.814
MOD_CK1_1	62	68	PF00069	0.575
MOD_CK1_1	70	76	PF00069	0.524
MOD_CK2_1	221	227	PF00069	0.806
MOD_CK2_1	268	274	PF00069	0.847
MOD_GlcNHglycan	189	192	PF01048	0.571
MOD_GlcNHglycan	251	254	PF01048	0.486
MOD_GlcNHglycan	72	75	PF01048	0.792
MOD_GSK3_1	12	19	PF00069	0.606
MOD_GSK3_1	221	228	PF00069	0.807
MOD_GSK3_1	266	273	PF00069	0.796
MOD_GSK3_1	59	66	PF00069	0.431
MOD_GSK3_1	69	76	PF00069	0.501
MOD_N-GLC_1	70	75	PF02516	0.820
MOD_NEK2_1	13	18	PF00069	0.547
MOD_NEK2_1	189	194	PF00069	0.779
MOD_PIKK_1	184	190	PF00454	0.828
MOD_PIKK_1	231	237	PF00454	0.804
MOD_PIKK_1	59	65	PF00454	0.426
MOD_PKA_2	7	13	PF00069	0.525
MOD_Plk_1	81	87	PF00069	0.464
MOD_Plk_4	263	269	PF00069	0.835
MOD_Plk_4	75	81	PF00069	0.584
MOD_Plk_4	82	88	PF00069	0.352
MOD_ProDKin_1	279	285	PF00069	0.848
MOD_ProDKin_1	63	69	PF00069	0.552
MOD_SUMO_for_1	115	118	PF00179	0.667
MOD_SUMO_rev_2	117	122	PF00179	0.671
TRG_ENDOCYTIC_2	260	263	PF00928	0.773
TRG_ENDOCYTIC_2	286	289	PF00928	0.783
TRG_ER_diArg_1	112	114	PF00400	0.701
TRG_ER_diArg_1	245	247	PF00400	0.851
TRG_ER_diArg_1	276	278	PF00400	0.780
TRG_ER_FFAT_2	262	273	PF00635	0.685
TRG_NLS_MonoCore_2	108	113	PF00514	0.580
TRG_NLS_MonoExtC_3	108	113	PF00514	0.702
TRG_NLS_MonoExtN_4	109	115	PF00514	0.582

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJD1	Leishmania donovani	100%	100%
A4HPN0	Leishmania braziliensis	61%	97%
E9ATE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q155	Leishmania major	89%	98%