Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ID06_LEIIN

TriTrypDb:

LINF_360047900

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ID06

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID06

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	221	225	PF00656	0.548
CLV_NRD_NRD_1	102	104	PF00675	0.673
CLV_PCSK_SKI1_1	223	227	PF00082	0.642
CLV_PCSK_SKI1_1	37	41	PF00082	0.550
DEG_Nend_Nbox_1	1	3	PF02207	0.631
DEG_SPOP_SBC_1	150	154	PF00917	0.577
DOC_CYCLIN_yCln2_LP_2	107	113	PF00134	0.650
DOC_MAPK_gen_1	166	175	PF00069	0.661
DOC_MAPK_gen_1	264	272	PF00069	0.599
DOC_MAPK_gen_1	34	43	PF00069	0.633
DOC_MAPK_MEF2A_6	37	45	PF00069	0.530
DOC_PP4_FxxP_1	45	48	PF00568	0.509
DOC_SPAK_OSR1_1	166	170	PF12202	0.694
DOC_USP7_MATH_1	130	134	PF00917	0.757
DOC_USP7_MATH_1	137	141	PF00917	0.736
DOC_USP7_MATH_1	146	150	PF00917	0.591
DOC_WW_Pin1_4	139	144	PF00397	0.742
DOC_WW_Pin1_4	192	197	PF00397	0.764
LIG_14-3-3_CanoR_1	37	42	PF00244	0.505
LIG_APCC_ABBA_1	64	69	PF00400	0.593
LIG_BRCT_BRCA1_1	171	175	PF00533	0.607
LIG_CaM_NSCaTE_8	95	102	PF13499	0.712
LIG_FHA_1	38	44	PF00498	0.488
LIG_FHA_1	85	91	PF00498	0.556
LIG_FHA_2	118	124	PF00498	0.649
LIG_FHA_2	150	156	PF00498	0.751
LIG_GBD_Chelix_1	169	177	PF00786	0.614
LIG_LIR_Apic_2	42	48	PF02991	0.510
LIG_LIR_Gen_1	268	274	PF02991	0.664
LIG_LIR_Nem_3	13	19	PF02991	0.549
LIG_LIR_Nem_3	268	272	PF02991	0.656
LIG_LIR_Nem_3	46	52	PF02991	0.528
LIG_NRBOX	172	178	PF00104	0.708
LIG_Pex14_2	45	49	PF04695	0.472
LIG_PTB_Apo_2	202	209	PF02174	0.719
LIG_SH2_SRC	55	58	PF00017	0.645
LIG_SH2_STAP1	11	15	PF00017	0.584
LIG_SH2_STAP1	16	20	PF00017	0.515
LIG_SH2_STAP1	55	59	PF00017	0.576
LIG_SH2_STAT5	19	22	PF00017	0.508
LIG_SH2_STAT5	269	272	PF00017	0.651
LIG_SH3_3	107	113	PF00018	0.752
LIG_SH3_3	190	196	PF00018	0.751
LIG_SH3_3	80	86	PF00018	0.546
LIG_SUMO_SIM_anti_2	40	46	PF11976	0.520
LIG_SUMO_SIM_par_1	86	91	PF11976	0.587
LIG_TRAF2_1	54	57	PF00917	0.542
LIG_TYR_ITIM	65	70	PF00017	0.704
MOD_CK1_1	149	155	PF00069	0.772
MOD_CK1_1	84	90	PF00069	0.611
MOD_CK2_1	117	123	PF00069	0.688
MOD_CK2_1	149	155	PF00069	0.751
MOD_CK2_1	50	56	PF00069	0.564
MOD_GlcNHglycan	132	135	PF01048	0.731
MOD_GlcNHglycan	148	151	PF01048	0.689
MOD_GlcNHglycan	196	199	PF01048	0.849
MOD_GlcNHglycan	272	275	PF01048	0.661
MOD_GlcNHglycan	34	37	PF01048	0.500
MOD_GlcNHglycan	51	55	PF01048	0.621
MOD_GlcNHglycan	83	86	PF01048	0.656
MOD_GSK3_1	117	124	PF00069	0.592
MOD_GSK3_1	146	153	PF00069	0.732
MOD_GSK3_1	18	25	PF00069	0.539
MOD_GSK3_1	84	91	PF00069	0.606
MOD_N-GLC_1	155	160	PF02516	0.722
MOD_NEK2_1	117	122	PF00069	0.763
MOD_NEK2_1	138	143	PF00069	0.711
MOD_NEK2_1	162	167	PF00069	0.687
MOD_NEK2_1	177	182	PF00069	0.666
MOD_NEK2_1	186	191	PF00069	0.670
MOD_NEK2_1	23	28	PF00069	0.657
MOD_NEK2_1	88	93	PF00069	0.585
MOD_Plk_1	187	193	PF00069	0.753
MOD_Plk_1	50	56	PF00069	0.564
MOD_Plk_4	238	244	PF00069	0.696
MOD_ProDKin_1	139	145	PF00069	0.743
MOD_ProDKin_1	192	198	PF00069	0.764
TRG_ENDOCYTIC_2	269	272	PF00928	0.651
TRG_ENDOCYTIC_2	67	70	PF00928	0.723

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6L2	Leptomonas seymouri	41%	100%
A0A3Q8IL86	Leishmania donovani	100%	100%
A4HPQ7	Leishmania braziliensis	73%	99%
E9ATH2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q125	Leishmania major	90%	100%