LeishMANIAdb
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FtsX-like permease family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
FtsX-like permease family protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4ID04_LEIIN
TriTrypDb:
LINF_360048100
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9

Expansion

Sequence features

A4ID04
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID04

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 34 38 PF00082 0.387
CLV_PCSK_SKI1_1 76 80 PF00082 0.464
DEG_APCC_DBOX_1 33 41 PF00400 0.562
DEG_APCC_DBOX_1 75 83 PF00400 0.278
DOC_USP7_MATH_1 124 128 PF00917 0.588
LIG_BRCT_BRCA1_1 46 50 PF00533 0.413
LIG_EVH1_2 70 74 PF00568 0.421
LIG_FHA_1 51 57 PF00498 0.481
LIG_FHA_1 86 92 PF00498 0.487
LIG_LIR_Nem_3 60 64 PF02991 0.437
LIG_NRBOX 36 42 PF00104 0.487
LIG_Pex14_2 74 78 PF04695 0.420
LIG_SH3_3 65 71 PF00018 0.412
LIG_SUMO_SIM_anti_2 45 51 PF11976 0.447
LIG_SUMO_SIM_anti_2 94 100 PF11976 0.404
LIG_SUMO_SIM_par_1 55 60 PF11976 0.417
LIG_SUMO_SIM_par_1 94 100 PF11976 0.473
LIG_TRFH_1 64 68 PF08558 0.399
LIG_UBA3_1 98 105 PF00899 0.426
LIG_WRC_WIRS_1 58 63 PF05994 0.542
LIG_WRC_WIRS_1 75 80 PF05994 0.414
MOD_CK1_1 127 133 PF00069 0.677
MOD_GlcNHglycan 50 53 PF01048 0.354
MOD_GlcNHglycan 7 10 PF01048 0.364
MOD_GSK3_1 44 51 PF00069 0.321
MOD_GSK3_1 97 104 PF00069 0.471
MOD_NEK2_1 101 106 PF00069 0.498
MOD_NEK2_1 116 121 PF00069 0.583
MOD_NEK2_1 42 47 PF00069 0.331
MOD_NEK2_1 50 55 PF00069 0.272
MOD_NEK2_1 57 62 PF00069 0.385
MOD_NEK2_1 74 79 PF00069 0.388
MOD_Plk_4 23 29 PF00069 0.412
MOD_Plk_4 44 50 PF00069 0.349
MOD_Plk_4 91 97 PF00069 0.391
TRG_DiLeu_BaEn_1 112 117 PF01217 0.610

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKW4 Leptomonas seymouri 72% 100%
A0A0S4JIM1 Bodo saltans 38% 100%
A0A1X0P3L7 Trypanosomatidae 40% 100%
A0A3S7XBF2 Leishmania donovani 100% 100%
A0A422NKK4 Trypanosoma rangeli 39% 100%
A4HPR0 Leishmania braziliensis 86% 100%
D0A8F5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
E9ATH4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4Q123 Leishmania major 95% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS