LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4ID01_LEIIN
TriTrypDb:
LINF_360048400 *
Length:
284

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ID01
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID01

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 133 135 PF00675 0.404
CLV_NRD_NRD_1 242 244 PF00675 0.482
CLV_NRD_NRD_1 47 49 PF00675 0.470
CLV_NRD_NRD_1 50 52 PF00675 0.450
CLV_PCSK_FUR_1 163 167 PF00082 0.440
CLV_PCSK_FUR_1 48 52 PF00082 0.409
CLV_PCSK_KEX2_1 165 167 PF00082 0.433
CLV_PCSK_KEX2_1 47 49 PF00082 0.527
CLV_PCSK_KEX2_1 50 52 PF00082 0.502
CLV_PCSK_KEX2_1 83 85 PF00082 0.621
CLV_PCSK_PC1ET2_1 165 167 PF00082 0.433
CLV_PCSK_PC1ET2_1 83 85 PF00082 0.612
CLV_Separin_Metazoa 126 130 PF03568 0.489
CLV_Separin_Metazoa 36 40 PF03568 0.474
DEG_APCC_DBOX_1 238 246 PF00400 0.440
DEG_Nend_UBRbox_2 1 3 PF02207 0.403
DOC_CKS1_1 179 184 PF01111 0.498
DOC_MAPK_gen_1 120 127 PF00069 0.464
DOC_MAPK_gen_1 243 253 PF00069 0.509
DOC_USP7_MATH_1 175 179 PF00917 0.435
DOC_WW_Pin1_4 178 183 PF00397 0.489
LIG_14-3-3_CanoR_1 12 16 PF00244 0.529
LIG_14-3-3_CanoR_1 183 189 PF00244 0.583
LIG_14-3-3_CanoR_1 88 97 PF00244 0.648
LIG_Actin_WH2_2 93 110 PF00022 0.467
LIG_APCC_ABBA_1 70 75 PF00400 0.494
LIG_APCC_ABBAyCdc20_2 86 92 PF00400 0.463
LIG_FHA_1 156 162 PF00498 0.433
LIG_FHA_1 208 214 PF00498 0.470
LIG_FHA_2 137 143 PF00498 0.516
LIG_GBD_Chelix_1 81 89 PF00786 0.506
LIG_LIR_LC3C_4 210 214 PF02991 0.468
LIG_LIR_Nem_3 24 29 PF02991 0.380
LIG_NRBOX 249 255 PF00104 0.500
LIG_PCNA_yPIPBox_3 27 38 PF02747 0.356
LIG_PCNA_yPIPBox_3 47 56 PF02747 0.517
LIG_SH2_CRK 26 30 PF00017 0.406
LIG_SH2_STAP1 132 136 PF00017 0.449
LIG_SH2_STAT5 272 275 PF00017 0.450
LIG_SUMO_SIM_par_1 157 162 PF11976 0.509
LIG_SUMO_SIM_par_1 252 258 PF11976 0.411
LIG_TRAF2_1 198 201 PF00917 0.429
LIG_TRAF2_1 258 261 PF00917 0.530
LIG_WRC_WIRS_1 256 261 PF05994 0.430
MOD_CDK_SPK_2 178 183 PF00069 0.489
MOD_CK1_1 178 184 PF00069 0.467
MOD_CK2_1 107 113 PF00069 0.313
MOD_CK2_1 120 126 PF00069 0.370
MOD_CK2_1 136 142 PF00069 0.507
MOD_CK2_1 255 261 PF00069 0.540
MOD_CK2_1 92 98 PF00069 0.631
MOD_GlcNHglycan 235 238 PF01048 0.646
MOD_GSK3_1 229 236 PF00069 0.591
MOD_GSK3_1 88 95 PF00069 0.632
MOD_N-GLC_1 102 107 PF02516 0.485
MOD_N-GLC_1 184 189 PF02516 0.508
MOD_NEK2_1 154 159 PF00069 0.440
MOD_NEK2_1 212 217 PF00069 0.446
MOD_NEK2_2 175 180 PF00069 0.442
MOD_PKA_1 120 126 PF00069 0.436
MOD_PKA_2 11 17 PF00069 0.405
MOD_PKB_1 86 94 PF00069 0.465
MOD_Plk_1 184 190 PF00069 0.543
MOD_Plk_1 207 213 PF00069 0.487
MOD_Plk_2-3 255 261 PF00069 0.428
MOD_Plk_2-3 92 98 PF00069 0.475
MOD_Plk_4 218 224 PF00069 0.501
MOD_ProDKin_1 178 184 PF00069 0.493
MOD_SUMO_for_1 148 151 PF00179 0.495
MOD_SUMO_for_1 164 167 PF00179 0.361
MOD_SUMO_for_1 223 226 PF00179 0.526
MOD_SUMO_for_1 59 62 PF00179 0.487
MOD_SUMO_rev_2 110 117 PF00179 0.500
TRG_DiLeu_BaEn_1 208 213 PF01217 0.465
TRG_DiLeu_BaEn_1 246 251 PF01217 0.506
TRG_DiLeu_BaEn_4 18 24 PF01217 0.353
TRG_ENDOCYTIC_2 26 29 PF00928 0.406
TRG_ENDOCYTIC_2 30 33 PF00928 0.305
TRG_ER_diArg_1 47 50 PF00400 0.512
TRG_ER_diArg_1 85 88 PF00400 0.552
TRG_Pf-PMV_PEXEL_1 192 196 PF00026 0.524
TRG_Pf-PMV_PEXEL_1 50 54 PF00026 0.471

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4I7 Leptomonas seymouri 69% 67%
A0A0S4JLH7 Bodo saltans 37% 80%
A0A3S7XBE4 Leishmania donovani 100% 100%
E9ATH7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
Q4Q120 Leishmania major 97% 100%
V5B6W3 Trypanosoma cruzi 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS