Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ID00_LEIIN

TriTrypDb:

LINF_360048500

Length:

1011

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ID00

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ID00

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	314	318	PF00656	0.750
CLV_C14_Caspase3-7	974	978	PF00656	0.700
CLV_NRD_NRD_1	349	351	PF00675	0.733
CLV_NRD_NRD_1	502	504	PF00675	0.741
CLV_NRD_NRD_1	532	534	PF00675	0.786
CLV_NRD_NRD_1	62	64	PF00675	0.769
CLV_NRD_NRD_1	743	745	PF00675	0.577
CLV_NRD_NRD_1	927	929	PF00675	0.712
CLV_NRD_NRD_1	998	1000	PF00675	0.769
CLV_PCSK_FUR_1	221	225	PF00082	0.611
CLV_PCSK_FUR_1	530	534	PF00082	0.786
CLV_PCSK_KEX2_1	223	225	PF00082	0.673
CLV_PCSK_KEX2_1	349	351	PF00082	0.774
CLV_PCSK_KEX2_1	353	355	PF00082	0.737
CLV_PCSK_KEX2_1	502	504	PF00082	0.805
CLV_PCSK_KEX2_1	532	534	PF00082	0.714
CLV_PCSK_KEX2_1	743	745	PF00082	0.577
CLV_PCSK_KEX2_1	886	888	PF00082	0.636
CLV_PCSK_KEX2_1	927	929	PF00082	0.715
CLV_PCSK_KEX2_1	998	1000	PF00082	0.772
CLV_PCSK_PC1ET2_1	223	225	PF00082	0.609
CLV_PCSK_PC1ET2_1	353	355	PF00082	0.791
CLV_PCSK_PC1ET2_1	886	888	PF00082	0.693
CLV_PCSK_PC7_1	349	355	PF00082	0.745
CLV_PCSK_PC7_1	994	1000	PF00082	0.717
CLV_PCSK_SKI1_1	571	575	PF00082	0.699
CLV_PCSK_SKI1_1	765	769	PF00082	0.716
CLV_PCSK_SKI1_1	791	795	PF00082	0.729
DEG_COP1_1	179	191	PF00400	0.608
DEG_COP1_1	373	385	PF00400	0.689
DEG_SCF_FBW7_1	445	452	PF00400	0.752
DEG_SPOP_SBC_1	141	145	PF00917	0.709
DEG_SPOP_SBC_1	518	522	PF00917	0.704
DEG_SPOP_SBC_1	675	679	PF00917	0.591
DOC_CKS1_1	21	26	PF01111	0.741
DOC_CYCLIN_RxL_1	788	797	PF00134	0.727
DOC_CYCLIN_yCln2_LP_2	129	135	PF00134	0.737
DOC_MAPK_HePTP_8	237	249	PF00069	0.609
DOC_MAPK_MEF2A_6	240	249	PF00069	0.621
DOC_PP2B_LxvP_1	129	132	PF13499	0.817
DOC_PP2B_LxvP_1	563	566	PF13499	0.721
DOC_PP4_FxxP_1	524	527	PF00568	0.800
DOC_PP4_FxxP_1	575	578	PF00568	0.735
DOC_USP7_MATH_1	123	127	PF00917	0.766
DOC_USP7_MATH_1	141	145	PF00917	0.530
DOC_USP7_MATH_1	176	180	PF00917	0.787
DOC_USP7_MATH_1	368	372	PF00917	0.694
DOC_USP7_MATH_1	39	43	PF00917	0.742
DOC_USP7_MATH_1	410	414	PF00917	0.868
DOC_USP7_MATH_1	440	444	PF00917	0.689
DOC_USP7_MATH_1	476	480	PF00917	0.686
DOC_USP7_MATH_1	518	522	PF00917	0.747
DOC_USP7_MATH_1	559	563	PF00917	0.732
DOC_USP7_MATH_1	675	679	PF00917	0.678
DOC_USP7_MATH_1	717	721	PF00917	0.649
DOC_USP7_MATH_1	956	960	PF00917	0.839
DOC_USP7_MATH_1	96	100	PF00917	0.763
DOC_USP7_MATH_2	9	15	PF00917	0.655
DOC_WW_Pin1_4	133	138	PF00397	0.702
DOC_WW_Pin1_4	20	25	PF00397	0.805
DOC_WW_Pin1_4	273	278	PF00397	0.531
DOC_WW_Pin1_4	326	331	PF00397	0.785
DOC_WW_Pin1_4	336	341	PF00397	0.621
DOC_WW_Pin1_4	356	361	PF00397	0.516
DOC_WW_Pin1_4	416	421	PF00397	0.751
DOC_WW_Pin1_4	445	450	PF00397	0.813
DOC_WW_Pin1_4	478	483	PF00397	0.674
DOC_WW_Pin1_4	514	519	PF00397	0.733
DOC_WW_Pin1_4	523	528	PF00397	0.670
DOC_WW_Pin1_4	561	566	PF00397	0.753
DOC_WW_Pin1_4	584	589	PF00397	0.746
DOC_WW_Pin1_4	671	676	PF00397	0.636
DOC_WW_Pin1_4	852	857	PF00397	0.745
DOC_WW_Pin1_4	862	867	PF00397	0.663
DOC_WW_Pin1_4	918	923	PF00397	0.805
LIG_14-3-3_CanoR_1	146	153	PF00244	0.699
LIG_14-3-3_CanoR_1	198	202	PF00244	0.686
LIG_14-3-3_CanoR_1	224	233	PF00244	0.562
LIG_14-3-3_CanoR_1	362	370	PF00244	0.762
LIG_14-3-3_CanoR_1	451	459	PF00244	0.709
LIG_14-3-3_CanoR_1	502	508	PF00244	0.750
LIG_14-3-3_CanoR_1	530	536	PF00244	0.750
LIG_14-3-3_CanoR_1	571	576	PF00244	0.752
LIG_14-3-3_CanoR_1	63	69	PF00244	0.724
LIG_14-3-3_CanoR_1	649	659	PF00244	0.735
LIG_14-3-3_CanoR_1	693	697	PF00244	0.655
LIG_14-3-3_CanoR_1	703	707	PF00244	0.642
LIG_Actin_WH2_2	556	573	PF00022	0.718
LIG_AP2alpha_2	982	984	PF02296	0.566
LIG_BIR_III_4	977	981	PF00653	0.742
LIG_BRCT_BRCA1_1	520	524	PF00533	0.809
LIG_BRCT_BRCA1_1	636	640	PF00533	0.672
LIG_CtBP_PxDLS_1	428	432	PF00389	0.746
LIG_FHA_1	232	238	PF00498	0.530
LIG_FHA_1	289	295	PF00498	0.618
LIG_FHA_1	32	38	PF00498	0.748
LIG_FHA_1	365	371	PF00498	0.791
LIG_FHA_1	372	378	PF00498	0.676
LIG_FHA_1	459	465	PF00498	0.756
LIG_FHA_1	574	580	PF00498	0.676
LIG_FHA_1	63	69	PF00498	0.613
LIG_FHA_1	651	657	PF00498	0.793
LIG_FHA_1	677	683	PF00498	0.688
LIG_FHA_1	900	906	PF00498	0.722
LIG_FHA_1	971	977	PF00498	0.622
LIG_FHA_2	294	300	PF00498	0.535
LIG_FHA_2	706	712	PF00498	0.636
LIG_FHA_2	764	770	PF00498	0.775
LIG_FHA_2	807	813	PF00498	0.675
LIG_FHA_2	972	978	PF00498	0.730
LIG_FHA_2	983	989	PF00498	0.589
LIG_HCF-1_HBM_1	842	845	PF13415	0.736
LIG_Integrin_RGD_1	724	726	PF01839	0.629
LIG_LIR_Apic_2	521	527	PF02991	0.800
LIG_LIR_Apic_2	572	578	PF02991	0.747
LIG_LIR_Gen_1	637	646	PF02991	0.764
LIG_LIR_Gen_1	704	714	PF02991	0.571
LIG_LIR_Gen_1	982	991	PF02991	0.568
LIG_LIR_Nem_3	879	885	PF02991	0.699
LIG_MYND_1	336	340	PF01753	0.682
LIG_SH2_STAT5	286	289	PF00017	0.483
LIG_SH2_STAT5	826	829	PF00017	0.783
LIG_SH2_STAT5	851	854	PF00017	0.782
LIG_SH2_STAT5	989	992	PF00017	0.698
LIG_SH3_1	783	789	PF00018	0.686
LIG_SH3_2	420	425	PF14604	0.713
LIG_SH3_2	786	791	PF14604	0.739
LIG_SH3_3	131	137	PF00018	0.686
LIG_SH3_3	202	208	PF00018	0.724
LIG_SH3_3	324	330	PF00018	0.738
LIG_SH3_3	386	392	PF00018	0.608
LIG_SH3_3	400	406	PF00018	0.642
LIG_SH3_3	417	423	PF00018	0.715
LIG_SH3_3	481	487	PF00018	0.819
LIG_SH3_3	653	659	PF00018	0.722
LIG_SH3_3	74	80	PF00018	0.740
LIG_SH3_3	783	789	PF00018	0.801
LIG_SH3_3	964	970	PF00018	0.814
LIG_TRAF2_1	312	315	PF00917	0.806
LIG_TRAF2_1	453	456	PF00917	0.756
LIG_TRAF2_1	594	597	PF00917	0.777
LIG_TRAF2_1	737	740	PF00917	0.587
LIG_TRAF2_1	811	814	PF00917	0.688
LIG_WW_3	788	792	PF00397	0.734
MOD_CDC14_SPxK_1	359	362	PF00782	0.730
MOD_CDK_SPxK_1	356	362	PF00069	0.725
MOD_CDK_SPxK_1	445	451	PF00069	0.752
MOD_CDK_SPxK_1	862	868	PF00069	0.780
MOD_CDK_SPxxK_3	478	485	PF00069	0.676
MOD_CDK_SPxxK_3	523	530	PF00069	0.733
MOD_CDK_SPxxK_3	918	925	PF00069	0.683
MOD_CK1_1	115	121	PF00069	0.715
MOD_CK1_1	14	20	PF00069	0.799
MOD_CK1_1	145	151	PF00069	0.750
MOD_CK1_1	152	158	PF00069	0.581
MOD_CK1_1	180	186	PF00069	0.639
MOD_CK1_1	263	269	PF00069	0.717
MOD_CK1_1	298	304	PF00069	0.728
MOD_CK1_1	326	332	PF00069	0.737
MOD_CK1_1	366	372	PF00069	0.731
MOD_CK1_1	378	384	PF00069	0.624
MOD_CK1_1	414	420	PF00069	0.796
MOD_CK1_1	465	471	PF00069	0.704
MOD_CK1_1	498	504	PF00069	0.807
MOD_CK1_1	517	523	PF00069	0.601
MOD_CK1_1	550	556	PF00069	0.809
MOD_CK1_1	602	608	PF00069	0.680
MOD_CK1_1	622	628	PF00069	0.508
MOD_CK1_1	67	73	PF00069	0.775
MOD_CK1_1	671	677	PF00069	0.776
MOD_CK1_1	705	711	PF00069	0.605
MOD_CK1_1	855	861	PF00069	0.710
MOD_CK1_1	99	105	PF00069	0.792
MOD_CK2_1	105	111	PF00069	0.674
MOD_CK2_1	223	229	PF00069	0.558
MOD_CK2_1	315	321	PF00069	0.805
MOD_CK2_1	336	342	PF00069	0.672
MOD_CK2_1	381	387	PF00069	0.826
MOD_CK2_1	450	456	PF00069	0.790
MOD_CK2_1	705	711	PF00069	0.637
MOD_CK2_1	735	741	PF00069	0.647
MOD_CK2_1	806	812	PF00069	0.670
MOD_CK2_1	928	934	PF00069	0.731
MOD_DYRK1A_RPxSP_1	356	360	PF00069	0.721
MOD_GlcNHglycan	114	117	PF01048	0.737
MOD_GlcNHglycan	125	128	PF01048	0.706
MOD_GlcNHglycan	148	151	PF01048	0.661
MOD_GlcNHglycan	16	19	PF01048	0.802
MOD_GlcNHglycan	250	253	PF01048	0.447
MOD_GlcNHglycan	302	305	PF01048	0.741
MOD_GlcNHglycan	464	467	PF01048	0.776
MOD_GlcNHglycan	549	552	PF01048	0.753
MOD_GlcNHglycan	584	587	PF01048	0.757
MOD_GlcNHglycan	617	620	PF01048	0.745
MOD_GlcNHglycan	684	687	PF01048	0.606
MOD_GlcNHglycan	719	722	PF01048	0.649
MOD_GlcNHglycan	796	799	PF01048	0.768
MOD_GlcNHglycan	81	84	PF01048	0.664
MOD_GlcNHglycan	834	837	PF01048	0.782
MOD_GlcNHglycan	916	919	PF01048	0.734
MOD_GlcNHglycan	929	933	PF01048	0.596
MOD_GlcNHglycan	977	981	PF01048	0.747
MOD_GSK3_1	141	148	PF00069	0.764
MOD_GSK3_1	165	172	PF00069	0.776
MOD_GSK3_1	176	183	PF00069	0.700
MOD_GSK3_1	293	300	PF00069	0.593
MOD_GSK3_1	364	371	PF00069	0.720
MOD_GSK3_1	397	404	PF00069	0.776
MOD_GSK3_1	410	417	PF00069	0.678
MOD_GSK3_1	440	447	PF00069	0.757
MOD_GSK3_1	458	465	PF00069	0.549
MOD_GSK3_1	466	473	PF00069	0.645
MOD_GSK3_1	491	498	PF00069	0.800
MOD_GSK3_1	514	521	PF00069	0.820
MOD_GSK3_1	569	576	PF00069	0.780
MOD_GSK3_1	598	605	PF00069	0.705
MOD_GSK3_1	615	622	PF00069	0.680
MOD_GSK3_1	63	70	PF00069	0.778
MOD_GSK3_1	630	637	PF00069	0.458
MOD_GSK3_1	650	657	PF00069	0.783
MOD_GSK3_1	667	674	PF00069	0.632
MOD_GSK3_1	701	708	PF00069	0.710
MOD_GSK3_1	759	766	PF00069	0.731
MOD_GSK3_1	843	850	PF00069	0.776
MOD_GSK3_1	852	859	PF00069	0.655
MOD_GSK3_1	914	921	PF00069	0.737
MOD_GSK3_1	956	963	PF00069	0.849
MOD_GSK3_1	96	103	PF00069	0.748
MOD_N-GLC_1	263	268	PF02516	0.544
MOD_N-GLC_1	273	278	PF02516	0.626
MOD_N-GLC_1	411	416	PF02516	0.789
MOD_N-GLC_1	99	104	PF02516	0.645
MOD_N-GLC_2	4	6	PF02516	0.791
MOD_NEK2_1	142	147	PF00069	0.774
MOD_NEK2_1	177	182	PF00069	0.719
MOD_NEK2_1	297	302	PF00069	0.594
MOD_NEK2_1	444	449	PF00069	0.808
MOD_NEK2_1	581	586	PF00069	0.714
MOD_NEK2_1	598	603	PF00069	0.632
MOD_NEK2_1	630	635	PF00069	0.666
MOD_NEK2_1	682	687	PF00069	0.709
MOD_NEK2_1	710	715	PF00069	0.616
MOD_NEK2_1	960	965	PF00069	0.612
MOD_NEK2_2	956	961	PF00069	0.611
MOD_PIKK_1	105	111	PF00454	0.674
MOD_PIKK_1	17	23	PF00454	0.800
MOD_PIKK_1	401	407	PF00454	0.813
MOD_PIKK_1	458	464	PF00454	0.721
MOD_PIKK_1	623	629	PF00454	0.504
MOD_PIKK_1	654	660	PF00454	0.721
MOD_PIKK_1	960	966	PF00454	0.722
MOD_PK_1	223	229	PF00069	0.558
MOD_PK_1	64	70	PF00069	0.611
MOD_PKA_1	223	229	PF00069	0.558
MOD_PKA_1	401	407	PF00069	0.813
MOD_PKA_1	63	69	PF00069	0.724
MOD_PKA_2	145	151	PF00069	0.699
MOD_PKA_2	197	203	PF00069	0.697
MOD_PKA_2	223	229	PF00069	0.558
MOD_PKA_2	245	251	PF00069	0.571
MOD_PKA_2	361	367	PF00069	0.769
MOD_PKA_2	371	377	PF00069	0.644
MOD_PKA_2	450	456	PF00069	0.774
MOD_PKA_2	531	537	PF00069	0.740
MOD_PKA_2	62	68	PF00069	0.788
MOD_PKA_2	692	698	PF00069	0.658
MOD_PKA_2	702	708	PF00069	0.644
MOD_PKA_2	806	812	PF00069	0.670
MOD_PKA_2	847	853	PF00069	0.766
MOD_PKA_2	993	999	PF00069	0.714
MOD_PKB_1	352	360	PF00069	0.685
MOD_PKB_1	699	707	PF00069	0.617
MOD_Plk_1	414	420	PF00069	0.853
MOD_Plk_1	440	446	PF00069	0.733
MOD_Plk_1	623	629	PF00069	0.689
MOD_Plk_1	701	707	PF00069	0.646
MOD_Plk_1	710	716	PF00069	0.508
MOD_Plk_1	841	847	PF00069	0.736
MOD_Plk_1	899	905	PF00069	0.634
MOD_Plk_1	99	105	PF00069	0.728
MOD_Plk_2-3	982	988	PF00069	0.548
MOD_Plk_4	440	446	PF00069	0.797
MOD_Plk_4	466	472	PF00069	0.672
MOD_Plk_4	519	525	PF00069	0.802
MOD_Plk_4	610	616	PF00069	0.724
MOD_Plk_4	692	698	PF00069	0.556
MOD_Plk_4	702	708	PF00069	0.641
MOD_Plk_4	847	853	PF00069	0.766
MOD_Plk_4	971	977	PF00069	0.622
MOD_ProDKin_1	133	139	PF00069	0.704
MOD_ProDKin_1	20	26	PF00069	0.804
MOD_ProDKin_1	273	279	PF00069	0.526
MOD_ProDKin_1	326	332	PF00069	0.785
MOD_ProDKin_1	336	342	PF00069	0.617
MOD_ProDKin_1	356	362	PF00069	0.519
MOD_ProDKin_1	416	422	PF00069	0.749
MOD_ProDKin_1	445	451	PF00069	0.816
MOD_ProDKin_1	478	484	PF00069	0.673
MOD_ProDKin_1	514	520	PF00069	0.733
MOD_ProDKin_1	523	529	PF00069	0.669
MOD_ProDKin_1	561	567	PF00069	0.753
MOD_ProDKin_1	584	590	PF00069	0.748
MOD_ProDKin_1	671	677	PF00069	0.633
MOD_ProDKin_1	852	858	PF00069	0.745
MOD_ProDKin_1	862	868	PF00069	0.666
MOD_ProDKin_1	918	924	PF00069	0.807
MOD_SUMO_for_1	436	439	PF00179	0.670
MOD_SUMO_rev_2	430	438	PF00179	0.688
MOD_SUMO_rev_2	946	956	PF00179	0.769
TRG_DiLeu_BaLyEn_6	202	207	PF01217	0.653
TRG_DiLeu_BaLyEn_6	333	338	PF01217	0.716
TRG_DiLeu_BaLyEn_6	865	870	PF01217	0.724
TRG_ENDOCYTIC_2	745	748	PF00928	0.667
TRG_ENDOCYTIC_2	885	888	PF00928	0.695
TRG_ER_diArg_1	349	352	PF00400	0.621
TRG_ER_diArg_1	529	532	PF00400	0.790
TRG_ER_diArg_1	55	58	PF00400	0.786
TRG_ER_diArg_1	646	649	PF00400	0.647
TRG_ER_diArg_1	743	745	PF00400	0.577
TRG_ER_diArg_1	926	928	PF00400	0.710
TRG_ER_diArg_1	991	994	PF00400	0.707
TRG_ER_diArg_1	997	999	PF00400	0.700
TRG_NLS_MonoExtC_3	351	356	PF00514	0.674
TRG_NLS_MonoExtN_4	349	356	PF00514	0.780
TRG_Pf-PMV_PEXEL_1	868	873	PF00026	0.781

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIW4	Leishmania donovani	99%	100%
A4HPR4	Leishmania braziliensis	66%	100%
E9ATH8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4Q119	Leishmania major	88%	100%