LeishMANIAdb
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Regulator_of_chromosome_condensation_(RCC1)_repea t

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Regulator_of_chromosome_condensation_(RCC1)_repea t
Gene product:
Regulator of chromosome condensation (RCC1) repeat - putative
Species:
Leishmania infantum
UniProt:
A4ICY9_LEIIN
TriTrypDb:
LINF_360049700
Length:
690

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005730 nucleolus 5 1
GO:0005737 cytoplasm 2 1
GO:0031010 ISWI-type complex 4 1
GO:0032991 protein-containing complex 1 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0070603 SWI/SNF superfamily-type complex 3 1
GO:0110165 cellular anatomical entity 1 1
GO:0140513 nuclear protein-containing complex 2 1
GO:1902494 catalytic complex 2 1
GO:1904949 ATPase complex 3 1

Expansion

Sequence features

A4ICY9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICY9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 217 219 PF00675 0.489
CLV_NRD_NRD_1 316 318 PF00675 0.413
CLV_NRD_NRD_1 65 67 PF00675 0.449
CLV_PCSK_KEX2_1 217 219 PF00082 0.567
CLV_PCSK_KEX2_1 638 640 PF00082 0.603
CLV_PCSK_KEX2_1 65 67 PF00082 0.418
CLV_PCSK_PC1ET2_1 638 640 PF00082 0.603
CLV_PCSK_SKI1_1 638 642 PF00082 0.607
CLV_PCSK_SKI1_1 65 69 PF00082 0.580
DEG_APCC_KENBOX_2 336 340 PF00400 0.508
DEG_Nend_Nbox_1 1 3 PF02207 0.350
DEG_SPOP_SBC_1 155 159 PF00917 0.415
DEG_SPOP_SBC_1 48 52 PF00917 0.744
DEG_SPOP_SBC_1 589 593 PF00917 0.694
DOC_CKS1_1 253 258 PF01111 0.449
DOC_CYCLIN_yCln2_LP_2 420 426 PF00134 0.522
DOC_CYCLIN_yCln2_LP_2 90 96 PF00134 0.553
DOC_MAPK_gen_1 264 272 PF00069 0.364
DOC_MAPK_MEF2A_6 266 274 PF00069 0.347
DOC_PP1_RVXF_1 309 315 PF00149 0.329
DOC_PP1_RVXF_1 639 645 PF00149 0.528
DOC_PP2B_LxvP_1 173 176 PF13499 0.515
DOC_USP7_MATH_1 370 374 PF00917 0.471
DOC_USP7_MATH_1 408 412 PF00917 0.537
DOC_USP7_MATH_1 46 50 PF00917 0.763
DOC_USP7_MATH_1 479 483 PF00917 0.635
DOC_USP7_MATH_1 579 583 PF00917 0.777
DOC_USP7_MATH_1 589 593 PF00917 0.736
DOC_USP7_MATH_1 616 620 PF00917 0.753
DOC_USP7_MATH_1 86 90 PF00917 0.455
DOC_USP7_MATH_1 98 102 PF00917 0.559
DOC_USP7_UBL2_3 459 463 PF12436 0.773
DOC_WW_Pin1_4 252 257 PF00397 0.413
DOC_WW_Pin1_4 29 34 PF00397 0.498
DOC_WW_Pin1_4 628 633 PF00397 0.761
LIG_14-3-3_CanoR_1 447 452 PF00244 0.722
LIG_14-3-3_CanoR_1 558 567 PF00244 0.416
LIG_14-3-3_CanoR_1 65 74 PF00244 0.465
LIG_APCC_ABBA_1 654 659 PF00400 0.526
LIG_BRCT_BRCA1_1 5 9 PF00533 0.439
LIG_BRCT_BRCA1_1 601 605 PF00533 0.673
LIG_CaM_IQ_9 57 73 PF13499 0.581
LIG_deltaCOP1_diTrp_1 643 649 PF00928 0.515
LIG_FHA_1 157 163 PF00498 0.437
LIG_FHA_1 241 247 PF00498 0.437
LIG_FHA_1 253 259 PF00498 0.369
LIG_FHA_1 331 337 PF00498 0.338
LIG_FHA_1 366 372 PF00498 0.530
LIG_FHA_1 432 438 PF00498 0.385
LIG_FHA_1 596 602 PF00498 0.771
LIG_FHA_2 266 272 PF00498 0.462
LIG_FHA_2 287 293 PF00498 0.328
LIG_FHA_2 466 472 PF00498 0.733
LIG_FHA_2 567 573 PF00498 0.538
LIG_FHA_2 660 666 PF00498 0.594
LIG_LIR_Apic_2 681 687 PF02991 0.673
LIG_LIR_Gen_1 167 176 PF02991 0.409
LIG_LIR_Gen_1 192 200 PF02991 0.488
LIG_LIR_Gen_1 482 491 PF02991 0.501
LIG_LIR_Nem_3 115 119 PF02991 0.461
LIG_LIR_Nem_3 167 173 PF02991 0.382
LIG_LIR_Nem_3 192 196 PF02991 0.405
LIG_LIR_Nem_3 226 232 PF02991 0.331
LIG_LIR_Nem_3 292 298 PF02991 0.328
LIG_LIR_Nem_3 482 486 PF02991 0.493
LIG_MYND_1 305 309 PF01753 0.449
LIG_NRBOX 508 514 PF00104 0.568
LIG_PCNA_yPIPBox_3 337 346 PF02747 0.536
LIG_PTB_Apo_2 110 117 PF02174 0.509
LIG_PTB_Phospho_1 110 116 PF10480 0.537
LIG_REV1ctd_RIR_1 292 301 PF16727 0.437
LIG_REV1ctd_RIR_1 346 355 PF16727 0.524
LIG_SH2_CRK 116 120 PF00017 0.529
LIG_SH2_CRK 399 403 PF00017 0.497
LIG_SH2_NCK_1 439 443 PF00017 0.417
LIG_SH2_PTP2 684 687 PF00017 0.660
LIG_SH2_SRC 189 192 PF00017 0.524
LIG_SH2_SRC 28 31 PF00017 0.423
LIG_SH2_SRC 505 508 PF00017 0.575
LIG_SH2_STAP1 126 130 PF00017 0.403
LIG_SH2_STAT3 525 528 PF00017 0.569
LIG_SH2_STAT3 7 10 PF00017 0.473
LIG_SH2_STAT5 163 166 PF00017 0.400
LIG_SH2_STAT5 28 31 PF00017 0.423
LIG_SH2_STAT5 288 291 PF00017 0.328
LIG_SH2_STAT5 347 350 PF00017 0.419
LIG_SH2_STAT5 392 395 PF00017 0.400
LIG_SH2_STAT5 399 402 PF00017 0.481
LIG_SH2_STAT5 516 519 PF00017 0.426
LIG_SH2_STAT5 525 528 PF00017 0.441
LIG_SH2_STAT5 684 687 PF00017 0.548
LIG_SH3_1 527 533 PF00018 0.552
LIG_SH3_2 530 535 PF14604 0.590
LIG_SH3_3 15 21 PF00018 0.573
LIG_SH3_3 250 256 PF00018 0.325
LIG_SH3_3 27 33 PF00018 0.432
LIG_SH3_3 309 315 PF00018 0.321
LIG_SH3_3 361 367 PF00018 0.523
LIG_SH3_3 442 448 PF00018 0.668
LIG_SH3_3 482 488 PF00018 0.513
LIG_SH3_3 527 533 PF00018 0.502
LIG_SH3_3 629 635 PF00018 0.723
LIG_SH3_CIN85_PxpxPR_1 530 535 PF14604 0.652
LIG_SUMO_SIM_par_1 330 338 PF11976 0.344
LIG_SUMO_SIM_par_1 597 603 PF11976 0.546
LIG_SUMO_SIM_par_1 650 662 PF11976 0.584
LIG_TRAF2_1 469 472 PF00917 0.748
LIG_TRAF2_1 501 504 PF00917 0.663
LIG_TRAF2_1 59 62 PF00917 0.558
LIG_TRAF2_1 622 625 PF00917 0.795
LIG_WW_3 314 318 PF00397 0.413
LIG_WW_3 532 536 PF00397 0.628
MOD_CDK_SPK_2 631 636 PF00069 0.712
MOD_CDK_SPxxK_3 631 638 PF00069 0.695
MOD_CK1_1 12 18 PF00069 0.591
MOD_CK1_1 431 437 PF00069 0.449
MOD_CK1_1 49 55 PF00069 0.775
MOD_CK1_1 590 596 PF00069 0.712
MOD_CK1_1 631 637 PF00069 0.700
MOD_CK2_1 220 226 PF00069 0.342
MOD_CK2_1 265 271 PF00069 0.467
MOD_CK2_1 286 292 PF00069 0.361
MOD_CK2_1 465 471 PF00069 0.771
MOD_CK2_1 56 62 PF00069 0.523
MOD_CK2_1 655 661 PF00069 0.525
MOD_Cter_Amidation 636 639 PF01082 0.642
MOD_GlcNHglycan 207 210 PF01048 0.483
MOD_GlcNHglycan 40 43 PF01048 0.708
MOD_GlcNHglycan 430 433 PF01048 0.464
MOD_GlcNHglycan 464 468 PF01048 0.785
MOD_GlcNHglycan 592 595 PF01048 0.750
MOD_GlcNHglycan 618 621 PF01048 0.759
MOD_GSK3_1 150 157 PF00069 0.340
MOD_GSK3_1 162 169 PF00069 0.307
MOD_GSK3_1 185 192 PF00069 0.536
MOD_GSK3_1 205 212 PF00069 0.186
MOD_GSK3_1 220 227 PF00069 0.371
MOD_GSK3_1 248 255 PF00069 0.433
MOD_GSK3_1 366 373 PF00069 0.476
MOD_GSK3_1 44 51 PF00069 0.743
MOD_GSK3_1 463 470 PF00069 0.734
MOD_GSK3_1 475 482 PF00069 0.638
MOD_GSK3_1 52 59 PF00069 0.679
MOD_GSK3_1 595 602 PF00069 0.688
MOD_GSK3_1 655 662 PF00069 0.529
MOD_N-GLC_1 209 214 PF02516 0.370
MOD_N-GLC_1 403 408 PF02516 0.479
MOD_N-GLC_1 44 49 PF02516 0.789
MOD_NEK2_1 139 144 PF00069 0.540
MOD_NEK2_1 3 8 PF00069 0.401
MOD_NEK2_1 341 346 PF00069 0.505
MOD_NEK2_1 9 14 PF00069 0.519
MOD_NEK2_2 166 171 PF00069 0.433
MOD_PIKK_1 191 197 PF00454 0.521
MOD_PIKK_1 240 246 PF00454 0.437
MOD_PIKK_1 383 389 PF00454 0.524
MOD_PIKK_1 410 416 PF00454 0.536
MOD_PIKK_1 608 614 PF00454 0.781
MOD_PIKK_1 9 15 PF00454 0.452
MOD_PKA_1 65 71 PF00069 0.358
MOD_PKA_2 150 156 PF00069 0.413
MOD_PKA_2 265 271 PF00069 0.449
MOD_PKA_2 377 383 PF00069 0.392
MOD_PKA_2 38 44 PF00069 0.732
MOD_PKA_2 65 71 PF00069 0.358
MOD_Plk_1 166 172 PF00069 0.336
MOD_Plk_1 209 215 PF00069 0.370
MOD_Plk_1 330 336 PF00069 0.328
MOD_Plk_1 659 665 PF00069 0.586
MOD_Plk_2-3 56 62 PF00069 0.621
MOD_Plk_2-3 659 665 PF00069 0.563
MOD_Plk_4 139 145 PF00069 0.486
MOD_Plk_4 150 156 PF00069 0.250
MOD_Plk_4 265 271 PF00069 0.387
MOD_Plk_4 330 336 PF00069 0.328
MOD_Plk_4 341 347 PF00069 0.465
MOD_Plk_4 359 365 PF00069 0.528
MOD_Plk_4 431 437 PF00069 0.417
MOD_Plk_4 441 447 PF00069 0.520
MOD_Plk_4 566 572 PF00069 0.488
MOD_Plk_4 595 601 PF00069 0.684
MOD_Plk_4 652 658 PF00069 0.587
MOD_Plk_4 86 92 PF00069 0.539
MOD_ProDKin_1 252 258 PF00069 0.413
MOD_ProDKin_1 29 35 PF00069 0.498
MOD_ProDKin_1 628 634 PF00069 0.756
MOD_SUMO_for_1 462 465 PF00179 0.752
MOD_SUMO_for_1 640 643 PF00179 0.608
MOD_SUMO_rev_2 451 460 PF00179 0.751
TRG_DiLeu_BaLyEn_6 319 324 PF01217 0.490
TRG_DiLeu_BaLyEn_6 337 342 PF01217 0.361
TRG_ENDOCYTIC_2 116 119 PF00928 0.529
TRG_ENDOCYTIC_2 229 232 PF00928 0.344
TRG_ENDOCYTIC_2 399 402 PF00928 0.488
TRG_ER_diArg_1 264 267 PF00400 0.388
TRG_ER_diArg_1 36 39 PF00400 0.626
TRG_ER_diArg_1 64 66 PF00400 0.441
TRG_NES_CRM1_1 62 73 PF08389 0.568
TRG_NLS_MonoExtC_3 637 643 PF00514 0.616
TRG_NLS_MonoExtN_4 635 642 PF00514 0.633

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4I0 Leptomonas seymouri 68% 100%
A0A0S4JSE7 Bodo saltans 32% 100%
A0A1X0P381 Trypanosomatidae 43% 100%
A0A3Q8IGE7 Leishmania donovani 100% 100%
A0A3S5IS08 Trypanosoma rangeli 45% 100%
A4HPS4 Leishmania braziliensis 83% 100%
D0A8N9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 43% 100%
E9ATI9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4Q109 Leishmania major 93% 100%
V5DNG6 Trypanosoma cruzi 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS