LeishMANIAdb
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Phosphoglycan beta 1,3 galactosyltransferase 4

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phosphoglycan beta 1,3 galactosyltransferase 4
Gene product:
phosphoglycan beta 1 -3 galactosyltransferase 4
Species:
Leishmania infantum
UniProt:
A4ICY7_LEIIN
TriTrypDb:
LINF_310041000
Length:
326

Annotations

LeishMANIAdb annotations

Phosphoglycan beta 1,3 galactosyltransferase (required for proper protective coat formation). Probably part of a much larger group. Expanded in Leishmaniids. Localization: Golgi (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3
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Phosphorylation

Amastigote: 27

Expansion

Sequence features

A4ICY7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICY7

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 3
GO:0016740 transferase activity 2 3
GO:0016757 glycosyltransferase activity 3 3
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 180 184 PF00656 0.450
CLV_NRD_NRD_1 149 151 PF00675 0.638
CLV_NRD_NRD_1 324 326 PF00675 0.700
CLV_NRD_NRD_1 93 95 PF00675 0.510
CLV_PCSK_KEX2_1 106 108 PF00082 0.258
CLV_PCSK_KEX2_1 138 140 PF00082 0.663
CLV_PCSK_KEX2_1 149 151 PF00082 0.651
CLV_PCSK_KEX2_1 314 316 PF00082 0.686
CLV_PCSK_KEX2_1 324 326 PF00082 0.658
CLV_PCSK_KEX2_1 93 95 PF00082 0.534
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7X8M5 Leishmania donovani 85% 91%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS