DNAJ protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ protein-like protein

Species:

Leishmania infantum

UniProt:

A4ICS3_LEIIN

TriTrypDb:

LINF_360011700

Length:

260

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ICS3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICS3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	146	148	PF00675	0.651
CLV_NRD_NRD_1	231	233	PF00675	0.323
CLV_PCSK_KEX2_1	188	190	PF00082	0.301
CLV_PCSK_KEX2_1	231	233	PF00082	0.326
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.312
CLV_PCSK_SKI1_1	113	117	PF00082	0.607
CLV_PCSK_SKI1_1	193	197	PF00082	0.323
CLV_PCSK_SKI1_1	216	220	PF00082	0.323
DEG_APCC_DBOX_1	146	154	PF00400	0.634
DEG_APCC_DBOX_1	162	170	PF00400	0.443
DOC_CKS1_1	68	73	PF01111	0.529
DOC_CYCLIN_RxL_1	188	201	PF00134	0.323
DOC_MAPK_gen_1	161	169	PF00069	0.534
DOC_MAPK_gen_1	188	198	PF00069	0.319
DOC_PP4_FxxP_1	68	71	PF00568	0.629
DOC_USP7_MATH_1	180	184	PF00917	0.449
DOC_USP7_MATH_1	32	36	PF00917	0.647
DOC_USP7_MATH_1	59	63	PF00917	0.611
DOC_USP7_UBL2_3	113	117	PF12436	0.596
DOC_USP7_UBL2_3	157	161	PF12436	0.567
DOC_USP7_UBL2_3	188	192	PF12436	0.395
DOC_USP7_UBL2_3	216	220	PF12436	0.323
DOC_WW_Pin1_4	49	54	PF00397	0.776
DOC_WW_Pin1_4	67	72	PF00397	0.546
LIG_14-3-3_CanoR_1	147	151	PF00244	0.628
LIG_APCC_ABBA_1	196	201	PF00400	0.323
LIG_EVH1_2	37	41	PF00568	0.531
LIG_FHA_1	11	17	PF00498	0.667
LIG_FHA_1	68	74	PF00498	0.563
LIG_FHA_2	147	153	PF00498	0.683
LIG_FHA_2	179	185	PF00498	0.383
LIG_FHA_2	206	212	PF00498	0.294
LIG_LIR_Apic_2	66	71	PF02991	0.633
LIG_LIR_Gen_1	17	28	PF02991	0.557
LIG_LIR_Nem_3	17	23	PF02991	0.551
LIG_LIR_Nem_3	213	218	PF02991	0.338
LIG_LIR_Nem_3	79	85	PF02991	0.607
LIG_Pex14_2	126	130	PF04695	0.498
LIG_PTB_Apo_2	62	69	PF02174	0.611
LIG_Rb_pABgroove_1	103	111	PF01858	0.669
LIG_SH2_CRK	173	177	PF00017	0.323
LIG_SH2_CRK	82	86	PF00017	0.665
LIG_SH2_NCK_1	120	124	PF00017	0.620
LIG_SH2_SRC	93	96	PF00017	0.610
LIG_SH2_STAP1	234	238	PF00017	0.459
LIG_SH2_STAT5	93	96	PF00017	0.633
LIG_SH3_3	22	28	PF00018	0.590
LIG_SH3_4	113	120	PF00018	0.633
LIG_TRAF2_1	182	185	PF00917	0.383
LIG_TRAF2_1	208	211	PF00917	0.310
LIG_UBA3_1	108	116	PF00899	0.599
LIG_UBA3_1	214	220	PF00899	0.323
LIG_WRC_WIRS_1	1	6	PF05994	0.604
MOD_CK1_1	10	16	PF00069	0.611
MOD_CK1_1	237	243	PF00069	0.610
MOD_CK1_1	43	49	PF00069	0.725
MOD_CK1_1	76	82	PF00069	0.621
MOD_CK1_1	97	103	PF00069	0.719
MOD_CK2_1	122	128	PF00069	0.678
MOD_CK2_1	178	184	PF00069	0.383
MOD_CK2_1	205	211	PF00069	0.298
MOD_CK2_1	223	229	PF00069	0.429
MOD_CK2_1	81	87	PF00069	0.695
MOD_Cter_Amidation	133	136	PF01082	0.651
MOD_GlcNHglycan	136	139	PF01048	0.610
MOD_GlcNHglycan	239	242	PF01048	0.639
MOD_GlcNHglycan	249	252	PF01048	0.560
MOD_GlcNHglycan	25	28	PF01048	0.728
MOD_GlcNHglycan	34	37	PF01048	0.630
MOD_GlcNHglycan	43	46	PF01048	0.629
MOD_GlcNHglycan	9	12	PF01048	0.588
MOD_GlcNHglycan	97	100	PF01048	0.647
MOD_GSK3_1	19	26	PF00069	0.599
MOD_GSK3_1	253	260	PF00069	0.520
MOD_GSK3_1	28	35	PF00069	0.620
MOD_GSK3_1	39	46	PF00069	0.649
MOD_GSK3_1	6	13	PF00069	0.626
MOD_GSK3_1	72	79	PF00069	0.605
MOD_N-GLC_1	23	28	PF02516	0.619
MOD_N-GLC_1	49	54	PF02516	0.646
MOD_N-GLC_1	6	11	PF02516	0.687
MOD_NEK2_1	109	114	PF00069	0.532
MOD_NEK2_1	19	24	PF00069	0.649
MOD_NEK2_1	39	44	PF00069	0.650
MOD_PIKK_1	205	211	PF00454	0.268
MOD_PIKK_1	45	51	PF00454	0.730
MOD_PK_1	81	87	PF00069	0.600
MOD_PKA_2	146	152	PF00069	0.652
MOD_Plk_1	234	240	PF00069	0.535
MOD_Plk_2-3	146	152	PF00069	0.602
MOD_Plk_2-3	223	229	PF00069	0.383
MOD_Plk_4	11	17	PF00069	0.572
MOD_Plk_4	122	128	PF00069	0.567
MOD_Plk_4	59	65	PF00069	0.589
MOD_ProDKin_1	49	55	PF00069	0.779
MOD_ProDKin_1	67	73	PF00069	0.545
MOD_SUMO_rev_2	145	150	PF00179	0.706
MOD_SUMO_rev_2	158	162	PF00179	0.513
MOD_SUMO_rev_2	183	190	PF00179	0.441
TRG_DiLeu_BaLyEn_6	162	167	PF01217	0.524
TRG_ENDOCYTIC_2	172	175	PF00928	0.338
TRG_ENDOCYTIC_2	82	85	PF00928	0.604
TRG_ER_diArg_1	162	165	PF00400	0.532
TRG_ER_diArg_1	231	233	PF00400	0.441
TRG_NLS_MonoExtN_4	189	196	PF00514	0.301

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W1	Leptomonas seymouri	58%	85%
A0A0S4J306	Bodo saltans	36%	100%
A0A3Q8IQI1	Leishmania donovani	100%	100%
A4HNS1	Leishmania braziliensis	73%	100%
E9ASI1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q215	Leishmania major	92%	100%