Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

KREPA4 - putative

Species:

Leishmania infantum

UniProt:

A4ICR5_LEIIN

TriTrypDb:

LINF_360012500

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ICR5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICR5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	209	211	PF00675	0.475
CLV_NRD_NRD_1	51	53	PF00675	0.604
CLV_NRD_NRD_1	61	63	PF00675	0.595
CLV_NRD_NRD_1	76	78	PF00675	0.520
CLV_PCSK_KEX2_1	132	134	PF00082	0.522
CLV_PCSK_KEX2_1	209	211	PF00082	0.475
CLV_PCSK_KEX2_1	51	53	PF00082	0.604
CLV_PCSK_KEX2_1	75	77	PF00082	0.547
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.598
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.604
CLV_PCSK_SKI1_1	12	16	PF00082	0.558
CLV_PCSK_SKI1_1	163	167	PF00082	0.448
CLV_PCSK_SKI1_1	209	213	PF00082	0.410
CLV_PCSK_SKI1_1	242	246	PF00082	0.472
CLV_PCSK_SKI1_1	27	31	PF00082	0.561
CLV_PCSK_SKI1_1	6	10	PF00082	0.544
CLV_PCSK_SKI1_1	62	66	PF00082	0.587
CLV_PCSK_SKI1_1	85	89	PF00082	0.563
DEG_Nend_UBRbox_1	1	4	PF02207	0.644
DEG_SPOP_SBC_1	64	68	PF00917	0.553
DOC_ANK_TNKS_1	260	267	PF00023	0.408
DOC_MAPK_DCC_7	242	251	PF00069	0.427
DOC_MAPK_MEF2A_6	242	251	PF00069	0.467
DOC_USP7_MATH_1	122	126	PF00917	0.609
DOC_USP7_MATH_1	17	21	PF00917	0.761
DOC_USP7_MATH_1	180	184	PF00917	0.590
DOC_USP7_MATH_1	196	200	PF00917	0.644
DOC_USP7_MATH_1	22	26	PF00917	0.703
DOC_USP7_MATH_1	42	46	PF00917	0.537
DOC_WW_Pin1_4	153	158	PF00397	0.437
DOC_WW_Pin1_4	164	169	PF00397	0.399
LIG_14-3-3_CanoR_1	12	22	PF00244	0.621
LIG_14-3-3_CanoR_1	51	56	PF00244	0.583
LIG_14-3-3_CanoR_1	62	71	PF00244	0.594
LIG_14-3-3_CanoR_1	85	93	PF00244	0.637
LIG_FHA_1	135	141	PF00498	0.552
LIG_FHA_1	21	27	PF00498	0.593
LIG_FHA_1	243	249	PF00498	0.425
LIG_LIR_Nem_3	68	74	PF02991	0.537
LIG_MYND_3	246	250	PF01753	0.483
LIG_PCNA_yPIPBox_3	222	236	PF02747	0.418
LIG_SH2_SRC	108	111	PF00017	0.444
LIG_SH2_STAT5	108	111	PF00017	0.541
LIG_SH3_3	241	247	PF00018	0.486
LIG_TRAF2_1	70	73	PF00917	0.538
MOD_CK1_1	153	159	PF00069	0.510
MOD_CK1_1	183	189	PF00069	0.624
MOD_CK1_1	20	26	PF00069	0.645
MOD_CK1_1	200	206	PF00069	0.564
MOD_CK1_1	45	51	PF00069	0.595
MOD_CK1_1	67	73	PF00069	0.601
MOD_CK2_1	22	28	PF00069	0.650
MOD_CK2_1	67	73	PF00069	0.551
MOD_Cter_Amidation	130	133	PF01082	0.538
MOD_GlcNHglycan	124	127	PF01048	0.548
MOD_GlcNHglycan	182	186	PF01048	0.497
MOD_GlcNHglycan	19	22	PF01048	0.685
MOD_GlcNHglycan	226	229	PF01048	0.379
MOD_GlcNHglycan	40	43	PF01048	0.685
MOD_GlcNHglycan	67	70	PF01048	0.590
MOD_GSK3_1	134	141	PF00069	0.529
MOD_GSK3_1	16	23	PF00069	0.675
MOD_GSK3_1	180	187	PF00069	0.651
MOD_GSK3_1	192	199	PF00069	0.568
MOD_GSK3_1	38	45	PF00069	0.587
MOD_GSK3_1	63	70	PF00069	0.595
MOD_GSK3_1	8	15	PF00069	0.727
MOD_N-GLC_1	12	17	PF02516	0.623
MOD_N-GLC_1	141	146	PF02516	0.468
MOD_N-GLC_1	42	47	PF02516	0.559
MOD_NEK2_1	150	155	PF00069	0.465
MOD_NEK2_1	256	261	PF00069	0.487
MOD_NEK2_1	8	13	PF00069	0.633
MOD_NEK2_2	103	108	PF00069	0.429
MOD_NEK2_2	22	27	PF00069	0.611
MOD_PIKK_1	190	196	PF00454	0.577
MOD_PKA_1	51	57	PF00069	0.594
MOD_PKA_1	62	68	PF00069	0.580
MOD_PKA_2	51	57	PF00069	0.594
MOD_Plk_1	27	33	PF00069	0.535
MOD_Plk_4	103	109	PF00069	0.530
MOD_Plk_4	197	203	PF00069	0.595
MOD_Plk_4	45	51	PF00069	0.680
MOD_ProDKin_1	153	159	PF00069	0.432
MOD_ProDKin_1	164	170	PF00069	0.396
MOD_SUMO_rev_2	55	65	PF00179	0.531
TRG_ENDOCYTIC_2	5	8	PF00928	0.522
TRG_ER_diArg_1	208	210	PF00400	0.495
TRG_ER_diArg_1	50	52	PF00400	0.608
TRG_NES_CRM1_1	239	250	PF08389	0.450
TRG_NLS_Bipartite_1	62	79	PF00514	0.494
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFQ8	Leptomonas seymouri	38%	89%
A0A3S7XAG1	Leishmania donovani	99%	100%
A4HNS9	Leishmania braziliensis	78%	100%
E9ASI9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q207	Leishmania major	90%	100%