LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Phosphorylation Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
zinc finger protein family member - putative
Species:
Leishmania infantum
UniProt:
A4ICR0_LEIIN
TriTrypDb:
LINF_360013000
Length:
543

Annotations

Annotations by Jardim et al.

Metal Binding, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 4
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 434

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4ICR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICR0

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 7
GO:0043167 ion binding 2 7
GO:0043169 cation binding 3 7
GO:0046872 metal ion binding 4 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 257 261 PF00656 0.516
CLV_C14_Caspase3-7 359 363 PF00656 0.330
CLV_C14_Caspase3-7 504 508 PF00656 0.434
CLV_C14_Caspase3-7 534 538 PF00656 0.477
CLV_NRD_NRD_1 468 470 PF00675 0.410
CLV_NRD_NRD_1 504 506 PF00675 0.400
CLV_PCSK_KEX2_1 470 472 PF00082 0.363
CLV_PCSK_PC1ET2_1 470 472 PF00082 0.363
CLV_PCSK_SKI1_1 273 277 PF00082 0.317
CLV_PCSK_SKI1_1 310 314 PF00082 0.398
DEG_ODPH_VHL_1 263 276 PF01847 0.334
DOC_CDC14_PxL_1 415 423 PF14671 0.354
DOC_MAPK_gen_1 202 209 PF00069 0.360
DOC_MAPK_gen_1 270 280 PF00069 0.307
DOC_MAPK_MEF2A_6 202 209 PF00069 0.360
DOC_MAPK_MEF2A_6 270 278 PF00069 0.311
DOC_MAPK_MEF2A_6 420 429 PF00069 0.334
DOC_MAPK_NFAT4_5 273 281 PF00069 0.333
DOC_MAPK_RevD_3 493 506 PF00069 0.356
DOC_PP2B_LxvP_1 370 373 PF13499 0.365
DOC_PP4_FxxP_1 280 283 PF00568 0.331
DOC_USP7_MATH_1 232 236 PF00917 0.621
DOC_USP7_MATH_1 340 344 PF00917 0.313
DOC_USP7_MATH_1 62 66 PF00917 0.626
DOC_USP7_UBL2_3 266 270 PF12436 0.405
DOC_USP7_UBL2_3 310 314 PF12436 0.389
DOC_USP7_UBL2_3 365 369 PF12436 0.401
DOC_USP7_UBL2_3 453 457 PF12436 0.349
DOC_USP7_UBL2_3 532 536 PF12436 0.473
DOC_WW_Pin1_4 188 193 PF00397 0.486
DOC_WW_Pin1_4 98 103 PF00397 0.655
LIG_14-3-3_CanoR_1 211 217 PF00244 0.458
LIG_APCC_ABBA_1 354 359 PF00400 0.327
LIG_BRCT_BRCA1_1 320 324 PF00533 0.350
LIG_BRCT_BRCA1_1 488 492 PF00533 0.336
LIG_eIF4E_1 441 447 PF01652 0.389
LIG_FHA_1 189 195 PF00498 0.422
LIG_FHA_1 199 205 PF00498 0.381
LIG_FHA_1 269 275 PF00498 0.369
LIG_FHA_1 424 430 PF00498 0.326
LIG_FHA_2 213 219 PF00498 0.494
LIG_FHA_2 435 441 PF00498 0.391
LIG_FHA_2 496 502 PF00498 0.356
LIG_LIR_Apic_2 279 283 PF02991 0.332
LIG_LIR_Apic_2 301 305 PF02991 0.435
LIG_LIR_Apic_2 334 340 PF02991 0.311
LIG_LIR_Gen_1 350 357 PF02991 0.330
LIG_LIR_Gen_1 489 497 PF02991 0.317
LIG_LIR_Nem_3 301 307 PF02991 0.354
LIG_LIR_Nem_3 334 339 PF02991 0.345
LIG_LIR_Nem_3 436 441 PF02991 0.350
LIG_LIR_Nem_3 489 495 PF02991 0.319
LIG_Pex14_2 364 368 PF04695 0.323
LIG_PTB_Apo_2 168 175 PF02174 0.518
LIG_SH2_CRK 337 341 PF00017 0.303
LIG_SH2_GRB2like 353 356 PF00017 0.351
LIG_SH2_STAP1 213 217 PF00017 0.450
LIG_SH2_STAP1 459 463 PF00017 0.490
LIG_SH2_STAT3 125 128 PF00017 0.575
LIG_SH2_STAT3 161 164 PF00017 0.642
LIG_SH2_STAT3 175 178 PF00017 0.420
LIG_SH2_STAT3 455 458 PF00017 0.346
LIG_SH2_STAT3 52 55 PF00017 0.640
LIG_SH2_STAT3 84 87 PF00017 0.516
LIG_SH2_STAT3 95 98 PF00017 0.541
LIG_SH2_STAT5 173 176 PF00017 0.596
LIG_SH2_STAT5 302 305 PF00017 0.350
LIG_SH2_STAT5 345 348 PF00017 0.298
LIG_SH2_STAT5 353 356 PF00017 0.323
LIG_SH2_STAT5 60 63 PF00017 0.549
LIG_SH2_STAT5 95 98 PF00017 0.568
LIG_SH3_2 119 124 PF14604 0.566
LIG_SH3_3 108 114 PF00018 0.568
LIG_SH3_3 115 121 PF00018 0.499
LIG_SH3_3 416 422 PF00018 0.356
LIG_TRAF2_1 498 501 PF00917 0.373
LIG_TYR_ITSM 332 339 PF00017 0.313
LIG_UBA3_1 204 208 PF00899 0.314
MOD_CK1_1 131 137 PF00069 0.554
MOD_CK1_1 246 252 PF00069 0.566
MOD_CK1_1 434 440 PF00069 0.417
MOD_CK2_1 236 242 PF00069 0.592
MOD_CK2_1 247 253 PF00069 0.507
MOD_CK2_1 391 397 PF00069 0.374
MOD_CK2_1 495 501 PF00069 0.345
MOD_Cter_Amidation 315 318 PF01082 0.365
MOD_GlcNHglycan 158 161 PF01048 0.618
MOD_GlcNHglycan 232 235 PF01048 0.653
MOD_GlcNHglycan 289 292 PF01048 0.384
MOD_GlcNHglycan 320 323 PF01048 0.357
MOD_GlcNHglycan 340 343 PF01048 0.388
MOD_GlcNHglycan 349 352 PF01048 0.291
MOD_GlcNHglycan 401 405 PF01048 0.421
MOD_GlcNHglycan 8 11 PF01048 0.548
MOD_GSK3_1 226 233 PF00069 0.568
MOD_GSK3_1 243 250 PF00069 0.451
MOD_GSK3_1 340 347 PF00069 0.334
MOD_GSK3_1 400 407 PF00069 0.421
MOD_N-GLC_1 131 136 PF02516 0.599
MOD_N-GLC_1 258 263 PF02516 0.459
MOD_N-GLC_1 404 409 PF02516 0.366
MOD_NEK2_1 276 281 PF00069 0.304
MOD_NEK2_1 287 292 PF00069 0.442
MOD_NEK2_1 300 305 PF00069 0.293
MOD_NEK2_1 486 491 PF00069 0.341
MOD_NEK2_2 340 345 PF00069 0.311
MOD_NEK2_2 423 428 PF00069 0.462
MOD_OFUCOSY 484 490 PF10250 0.313
MOD_PIKK_1 113 119 PF00454 0.654
MOD_PIKK_1 47 53 PF00454 0.681
MOD_PIKK_1 78 84 PF00454 0.613
MOD_PIKK_1 93 99 PF00454 0.524
MOD_PK_1 203 209 PF00069 0.353
MOD_Plk_1 258 264 PF00069 0.489
MOD_Plk_1 300 306 PF00069 0.362
MOD_Plk_1 404 410 PF00069 0.360
MOD_Plk_1 423 429 PF00069 0.336
MOD_Plk_4 107 113 PF00069 0.616
MOD_Plk_4 236 242 PF00069 0.536
MOD_Plk_4 276 282 PF00069 0.308
MOD_Plk_4 340 346 PF00069 0.311
MOD_ProDKin_1 188 194 PF00069 0.474
MOD_ProDKin_1 98 104 PF00069 0.654
MOD_SUMO_for_1 312 315 PF00179 0.400
MOD_SUMO_rev_2 239 246 PF00179 0.586
MOD_SUMO_rev_2 262 272 PF00179 0.501
MOD_SUMO_rev_2 311 319 PF00179 0.366
MOD_SUMO_rev_2 499 508 PF00179 0.393
MOD_SUMO_rev_2 528 538 PF00179 0.476
TRG_DiLeu_BaEn_2 487 493 PF01217 0.322
TRG_ENDOCYTIC_2 213 216 PF00928 0.438
TRG_ENDOCYTIC_2 336 339 PF00928 0.297
TRG_ENDOCYTIC_2 353 356 PF00928 0.323
TRG_ER_diArg_1 469 472 PF00400 0.381
TRG_NLS_MonoExtN_4 467 473 PF00514 0.375

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7W2 Leptomonas seymouri 68% 100%
A0A3S7XAD2 Leishmania donovani 100% 100%
A4HNT4 Leishmania braziliensis 84% 100%
E9ASJ4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 99%
Q4Q202 Leishmania major 96% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS