LeishMANIAdb
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Zinc_finger_protein_-_putative

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Zinc_finger_protein_-_putative
Gene product:
zinc finger protein family member - putative
Species:
Leishmania infantum
UniProt:
A4ICQ0_LEIIN
TriTrypDb:
LINF_360014100
Length:
786

Annotations

Annotations by Jardim et al.

Metal Binding, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Phosphorylation

Promastigote: 495

Expansion

Sequence features

A4ICQ0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICQ0

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 7
GO:0043167 ion binding 2 7
GO:0043169 cation binding 3 7
GO:0046872 metal ion binding 4 7
GO:0003676 nucleic acid binding 3 1
GO:0003723 RNA binding 4 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 444 448 PF00656 0.669
CLV_C14_Caspase3-7 523 527 PF00656 0.606
CLV_C14_Caspase3-7 753 757 PF00656 0.730
CLV_NRD_NRD_1 383 385 PF00675 0.410
CLV_NRD_NRD_1 404 406 PF00675 0.544
CLV_NRD_NRD_1 490 492 PF00675 0.670
CLV_NRD_NRD_1 568 570 PF00675 0.556
CLV_PCSK_FUR_1 243 247 PF00082 0.491
CLV_PCSK_FUR_1 402 406 PF00082 0.533
CLV_PCSK_KEX2_1 245 247 PF00082 0.512
CLV_PCSK_KEX2_1 404 406 PF00082 0.544
CLV_PCSK_KEX2_1 422 424 PF00082 0.481
CLV_PCSK_KEX2_1 490 492 PF00082 0.670
CLV_PCSK_KEX2_1 568 570 PF00082 0.556
CLV_PCSK_PC1ET2_1 245 247 PF00082 0.593
CLV_PCSK_PC1ET2_1 422 424 PF00082 0.481
CLV_PCSK_SKI1_1 342 346 PF00082 0.409
CLV_PCSK_SKI1_1 722 726 PF00082 0.741
CLV_PCSK_SKI1_1 749 753 PF00082 0.721
CLV_Separin_Metazoa 408 412 PF03568 0.451
DEG_Nend_Nbox_1 1 3 PF02207 0.680
DEG_SPOP_SBC_1 671 675 PF00917 0.760
DEG_SPOP_SBC_1 705 709 PF00917 0.698
DEG_SPOP_SBC_1 755 759 PF00917 0.653
DOC_CKS1_1 124 129 PF01111 0.452
DOC_CKS1_1 551 556 PF01111 0.617
DOC_CKS1_1 716 721 PF01111 0.730
DOC_CYCLIN_RxL_1 339 348 PF00134 0.412
DOC_CYCLIN_yCln2_LP_2 119 125 PF00134 0.502
DOC_MAPK_gen_1 277 287 PF00069 0.381
DOC_MAPK_gen_1 350 357 PF00069 0.397
DOC_MAPK_gen_1 400 409 PF00069 0.537
DOC_MAPK_gen_1 565 573 PF00069 0.544
DOC_MAPK_MEF2A_6 220 227 PF00069 0.380
DOC_MAPK_MEF2A_6 350 359 PF00069 0.478
DOC_PP2B_LxvP_1 119 122 PF13499 0.511
DOC_PP4_FxxP_1 140 143 PF00568 0.501
DOC_USP7_MATH_1 226 230 PF00917 0.376
DOC_USP7_MATH_1 427 431 PF00917 0.583
DOC_USP7_MATH_1 484 488 PF00917 0.639
DOC_USP7_MATH_1 517 521 PF00917 0.612
DOC_USP7_MATH_1 525 529 PF00917 0.656
DOC_USP7_MATH_1 57 61 PF00917 0.618
DOC_USP7_MATH_1 697 701 PF00917 0.664
DOC_USP7_MATH_1 705 709 PF00917 0.633
DOC_USP7_MATH_1 740 744 PF00917 0.712
DOC_USP7_MATH_1 747 751 PF00917 0.657
DOC_USP7_MATH_1 755 759 PF00917 0.568
DOC_WW_Pin1_4 123 128 PF00397 0.504
DOC_WW_Pin1_4 389 394 PF00397 0.629
DOC_WW_Pin1_4 5 10 PF00397 0.630
DOC_WW_Pin1_4 550 555 PF00397 0.626
DOC_WW_Pin1_4 572 577 PF00397 0.594
DOC_WW_Pin1_4 659 664 PF00397 0.703
DOC_WW_Pin1_4 715 720 PF00397 0.729
LIG_14-3-3_CanoR_1 201 205 PF00244 0.477
LIG_14-3-3_CanoR_1 309 314 PF00244 0.379
LIG_14-3-3_CanoR_1 491 497 PF00244 0.637
LIG_14-3-3_CanoR_1 505 515 PF00244 0.606
LIG_14-3-3_CanoR_1 749 755 PF00244 0.735
LIG_BRCT_BRCA1_1 228 232 PF00533 0.369
LIG_BRCT_BRCA1_1 511 515 PF00533 0.570
LIG_BRCT_BRCA1_1 657 661 PF00533 0.674
LIG_BRCT_BRCA1_2 228 234 PF00533 0.366
LIG_Clathr_ClatBox_1 666 670 PF01394 0.707
LIG_deltaCOP1_diTrp_1 656 661 PF00928 0.672
LIG_FHA_1 209 215 PF00498 0.408
LIG_FHA_1 231 237 PF00498 0.373
LIG_FHA_1 269 275 PF00498 0.483
LIG_FHA_1 316 322 PF00498 0.433
LIG_FHA_1 662 668 PF00498 0.642
LIG_FHA_2 183 189 PF00498 0.417
LIG_FHA_2 318 324 PF00498 0.400
LIG_FHA_2 442 448 PF00498 0.621
LIG_IBAR_NPY_1 516 518 PF08397 0.579
LIG_Integrin_isoDGR_2 87 89 PF01839 0.646
LIG_LIR_Apic_2 20 25 PF02991 0.684
LIG_LIR_Apic_2 37 42 PF02991 0.535
LIG_LIR_Apic_2 700 705 PF02991 0.693
LIG_LIR_Gen_1 209 219 PF02991 0.503
LIG_LIR_Gen_1 300 311 PF02991 0.398
LIG_LIR_Gen_1 528 535 PF02991 0.688
LIG_LIR_Nem_3 16 22 PF02991 0.650
LIG_LIR_Nem_3 209 215 PF02991 0.414
LIG_LIR_Nem_3 300 306 PF02991 0.398
LIG_LIR_Nem_3 512 518 PF02991 0.593
LIG_LIR_Nem_3 528 534 PF02991 0.682
LIG_PALB2_WD40_1 298 306 PF16756 0.396
LIG_Pex14_2 299 303 PF04695 0.394
LIG_Pex14_2 655 659 PF04695 0.671
LIG_PTB_Apo_2 305 312 PF02174 0.404
LIG_SH2_CRK 22 26 PF00017 0.760
LIG_SH2_CRK 39 43 PF00017 0.621
LIG_SH2_CRK 518 522 PF00017 0.677
LIG_SH2_CRK 624 628 PF00017 0.700
LIG_SH2_NCK_1 22 26 PF00017 0.794
LIG_SH2_PTP2 237 240 PF00017 0.510
LIG_SH2_PTP2 702 705 PF00017 0.651
LIG_SH2_SRC 22 25 PF00017 0.681
LIG_SH2_SRC 237 240 PF00017 0.510
LIG_SH2_SRC 702 705 PF00017 0.651
LIG_SH2_STAP1 19 23 PF00017 0.691
LIG_SH2_STAT3 104 107 PF00017 0.681
LIG_SH2_STAT5 181 184 PF00017 0.485
LIG_SH2_STAT5 237 240 PF00017 0.510
LIG_SH2_STAT5 28 31 PF00017 0.641
LIG_SH2_STAT5 310 313 PF00017 0.398
LIG_SH2_STAT5 379 382 PF00017 0.360
LIG_SH2_STAT5 552 555 PF00017 0.698
LIG_SH2_STAT5 702 705 PF00017 0.651
LIG_SH3_3 121 127 PF00018 0.447
LIG_SH3_3 140 146 PF00018 0.361
LIG_SH3_3 220 226 PF00018 0.386
LIG_SH3_3 318 324 PF00018 0.400
LIG_SH3_3 428 434 PF00018 0.494
LIG_SH3_3 624 630 PF00018 0.651
LIG_SUMO_SIM_par_1 121 126 PF11976 0.395
LIG_SUMO_SIM_par_1 569 575 PF11976 0.535
LIG_SxIP_EBH_1 763 774 PF03271 0.611
LIG_TRAF2_1 160 163 PF00917 0.386
LIG_TRAF2_1 454 457 PF00917 0.630
LIG_TRFH_1 311 315 PF08558 0.403
MOD_CDK_SPxxK_3 715 722 PF00069 0.730
MOD_CK1_1 13 19 PF00069 0.624
MOD_CK1_1 208 214 PF00069 0.476
MOD_CK1_1 328 334 PF00069 0.410
MOD_CK1_1 483 489 PF00069 0.622
MOD_CK1_1 509 515 PF00069 0.585
MOD_CK1_1 520 526 PF00069 0.681
MOD_CK1_1 561 567 PF00069 0.745
MOD_CK1_1 575 581 PF00069 0.544
MOD_CK1_1 672 678 PF00069 0.760
MOD_CK1_1 698 704 PF00069 0.697
MOD_CK1_1 707 713 PF00069 0.611
MOD_CK1_1 726 732 PF00069 0.710
MOD_CK1_1 739 745 PF00069 0.575
MOD_CK1_1 750 756 PF00069 0.616
MOD_CK1_1 766 772 PF00069 0.555
MOD_CK2_1 107 113 PF00069 0.509
MOD_CK2_1 182 188 PF00069 0.428
MOD_CMANNOS 278 281 PF00535 0.400
MOD_GlcNHglycan 12 15 PF01048 0.615
MOD_GlcNHglycan 135 138 PF01048 0.567
MOD_GlcNHglycan 48 51 PF01048 0.623
MOD_GlcNHglycan 482 485 PF01048 0.721
MOD_GlcNHglycan 494 497 PF01048 0.615
MOD_GlcNHglycan 501 504 PF01048 0.566
MOD_GlcNHglycan 539 542 PF01048 0.803
MOD_GlcNHglycan 577 580 PF01048 0.650
MOD_GlcNHglycan 738 741 PF01048 0.663
MOD_GlcNHglycan 749 752 PF01048 0.662
MOD_GlcNHglycan 77 80 PF01048 0.611
MOD_GSK3_1 126 133 PF00069 0.438
MOD_GSK3_1 13 20 PF00069 0.621
MOD_GSK3_1 226 233 PF00069 0.376
MOD_GSK3_1 476 483 PF00069 0.634
MOD_GSK3_1 546 553 PF00069 0.697
MOD_GSK3_1 655 662 PF00069 0.681
MOD_GSK3_1 669 676 PF00069 0.671
MOD_GSK3_1 704 711 PF00069 0.666
MOD_GSK3_1 722 729 PF00069 0.802
MOD_GSK3_1 736 743 PF00069 0.727
MOD_GSK3_1 750 757 PF00069 0.582
MOD_GSK3_1 765 772 PF00069 0.549
MOD_N-GLC_1 10 15 PF02516 0.584
MOD_N-GLC_1 484 489 PF02516 0.623
MOD_N-GLC_1 492 497 PF02516 0.625
MOD_N-GLC_1 546 551 PF02516 0.625
MOD_N-GLC_1 678 683 PF02516 0.738
MOD_N-GLC_1 698 703 PF02516 0.689
MOD_N-GLC_1 726 731 PF02516 0.658
MOD_N-GLC_1 75 80 PF02516 0.724
MOD_NEK2_1 182 187 PF00069 0.396
MOD_NEK2_1 230 235 PF00069 0.445
MOD_NEK2_1 326 331 PF00069 0.420
MOD_NEK2_1 345 350 PF00069 0.634
MOD_NEK2_1 492 497 PF00069 0.625
MOD_NEK2_1 559 564 PF00069 0.549
MOD_NEK2_1 655 660 PF00069 0.673
MOD_NEK2_1 669 674 PF00069 0.567
MOD_NEK2_1 695 700 PF00069 0.682
MOD_NEK2_1 736 741 PF00069 0.753
MOD_NEK2_1 763 768 PF00069 0.803
MOD_NEK2_2 34 39 PF00069 0.707
MOD_OFUCOSY 364 369 PF10250 0.500
MOD_PIKK_1 441 447 PF00454 0.554
MOD_PIKK_1 708 714 PF00454 0.710
MOD_PK_1 210 216 PF00069 0.475
MOD_PK_1 351 357 PF00069 0.382
MOD_PK_1 678 684 PF00069 0.737
MOD_PKA_1 422 428 PF00069 0.490
MOD_PKA_2 200 206 PF00069 0.447
MOD_PKA_2 422 428 PF00069 0.543
MOD_PKA_2 537 543 PF00069 0.648
MOD_PKA_2 773 779 PF00069 0.693
MOD_Plk_1 187 193 PF00069 0.543
MOD_Plk_1 208 214 PF00069 0.455
MOD_Plk_1 315 321 PF00069 0.431
MOD_Plk_1 484 490 PF00069 0.634
MOD_Plk_1 497 503 PF00069 0.675
MOD_Plk_1 655 661 PF00069 0.786
MOD_Plk_1 698 704 PF00069 0.692
MOD_Plk_2-3 317 323 PF00069 0.395
MOD_Plk_4 126 132 PF00069 0.422
MOD_Plk_4 17 23 PF00069 0.731
MOD_Plk_4 188 194 PF00069 0.482
MOD_Plk_4 226 232 PF00069 0.363
MOD_Plk_4 698 704 PF00069 0.642
MOD_Plk_4 773 779 PF00069 0.760
MOD_ProDKin_1 123 129 PF00069 0.498
MOD_ProDKin_1 389 395 PF00069 0.629
MOD_ProDKin_1 5 11 PF00069 0.629
MOD_ProDKin_1 550 556 PF00069 0.622
MOD_ProDKin_1 572 578 PF00069 0.602
MOD_ProDKin_1 659 665 PF00069 0.703
MOD_ProDKin_1 715 721 PF00069 0.729
MOD_SUMO_for_1 415 418 PF00179 0.511
MOD_SUMO_rev_2 213 222 PF00179 0.482
MOD_SUMO_rev_2 446 454 PF00179 0.695
TRG_DiLeu_BaEn_4 398 404 PF01217 0.523
TRG_DiLeu_BaLyEn_6 662 667 PF01217 0.685
TRG_ENDOCYTIC_2 310 313 PF00928 0.398
TRG_ENDOCYTIC_2 379 382 PF00928 0.360
TRG_ENDOCYTIC_2 518 521 PF00928 0.592
TRG_ENDOCYTIC_2 531 534 PF00928 0.651
TRG_ENDOCYTIC_2 624 627 PF00928 0.701
TRG_ER_diArg_1 402 405 PF00400 0.543
TRG_ER_diArg_1 490 492 PF00400 0.652
TRG_ER_diArg_1 567 569 PF00400 0.554
TRG_NLS_MonoExtN_4 243 249 PF00514 0.591
TRG_Pf-PMV_PEXEL_1 342 346 PF00026 0.409

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDN9 Leptomonas seymouri 58% 100%
A0A3S7XAM4 Leishmania donovani 99% 100%
A4HNU4 Leishmania braziliensis 81% 100%
E9ASK4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q1Z2 Leishmania major 94% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS