Putative DEAH-box RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

pre-mRNA splicing factor ATP-dependent RNA helicase - putative

Species:

Leishmania infantum

UniProt:

A4ICP7_LEIIN

TriTrypDb:

LINF_360014400

Length:

944

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005681	spliceosomal complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0110165	cellular anatomical entity	1	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

A4ICP7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICP7

Function

Biological processes
Term	Name	Level	Count
GO:0000375	RNA splicing, via transesterification reactions	8	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0008380	RNA splicing	7	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003723	RNA binding	4	1
GO:0016787	hydrolase activity	2	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	613	617	PF00656	0.357
CLV_C14_Caspase3-7	773	777	PF00656	0.684
CLV_C14_Caspase3-7	782	786	PF00656	0.623
CLV_NRD_NRD_1	18	20	PF00675	0.516
CLV_NRD_NRD_1	190	192	PF00675	0.473
CLV_NRD_NRD_1	241	243	PF00675	0.322
CLV_NRD_NRD_1	287	289	PF00675	0.262
CLV_NRD_NRD_1	374	376	PF00675	0.253
CLV_NRD_NRD_1	501	503	PF00675	0.256
CLV_NRD_NRD_1	647	649	PF00675	0.275
CLV_NRD_NRD_1	7	9	PF00675	0.526
CLV_NRD_NRD_1	74	76	PF00675	0.624
CLV_NRD_NRD_1	865	867	PF00675	0.620
CLV_NRD_NRD_1	901	903	PF00675	0.572
CLV_NRD_NRD_1	938	940	PF00675	0.610
CLV_PCSK_KEX2_1	190	192	PF00082	0.502
CLV_PCSK_KEX2_1	243	245	PF00082	0.272
CLV_PCSK_KEX2_1	287	289	PF00082	0.278
CLV_PCSK_KEX2_1	374	376	PF00082	0.253
CLV_PCSK_KEX2_1	647	649	PF00082	0.275
CLV_PCSK_KEX2_1	7	9	PF00082	0.587
CLV_PCSK_KEX2_1	73	75	PF00082	0.605
CLV_PCSK_KEX2_1	840	842	PF00082	0.655
CLV_PCSK_KEX2_1	901	903	PF00082	0.523
CLV_PCSK_KEX2_1	905	907	PF00082	0.398
CLV_PCSK_KEX2_1	940	942	PF00082	0.651
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.272
CLV_PCSK_PC1ET2_1	840	842	PF00082	0.667
CLV_PCSK_PC1ET2_1	905	907	PF00082	0.435
CLV_PCSK_PC1ET2_1	940	942	PF00082	0.651
CLV_PCSK_PC7_1	370	376	PF00082	0.311
CLV_PCSK_PC7_1	901	907	PF00082	0.470
CLV_PCSK_SKI1_1	14	18	PF00082	0.517
CLV_PCSK_SKI1_1	243	247	PF00082	0.299
CLV_PCSK_SKI1_1	3	7	PF00082	0.597
CLV_PCSK_SKI1_1	325	329	PF00082	0.253
CLV_PCSK_SKI1_1	336	340	PF00082	0.277
CLV_PCSK_SKI1_1	474	478	PF00082	0.270
CLV_PCSK_SKI1_1	570	574	PF00082	0.403
CLV_PCSK_SKI1_1	691	695	PF00082	0.338
CLV_PCSK_SKI1_1	743	747	PF00082	0.383
CLV_PCSK_SKI1_1	749	753	PF00082	0.357
CLV_PCSK_SKI1_1	75	79	PF00082	0.651
CLV_PCSK_SKI1_1	805	809	PF00082	0.360
CLV_PCSK_SKI1_1	906	910	PF00082	0.533
CLV_Separin_Metazoa	588	592	PF03568	0.389
DEG_APCC_DBOX_1	198	206	PF00400	0.319
DEG_APCC_DBOX_1	748	756	PF00400	0.400
DEG_Nend_UBRbox_2	1	3	PF02207	0.580
DOC_AGCK_PIF_1	572	577	PF00069	0.481
DOC_CKS1_1	246	251	PF01111	0.556
DOC_CYCLIN_RxL_1	240	248	PF00134	0.472
DOC_CYCLIN_RxL_1	319	331	PF00134	0.476
DOC_CYCLIN_RxL_1	802	809	PF00134	0.411
DOC_CYCLIN_yCln2_LP_2	246	252	PF00134	0.546
DOC_MAPK_DCC_7	470	478	PF00069	0.528
DOC_MAPK_gen_1	204	214	PF00069	0.471
DOC_MAPK_gen_1	287	294	PF00069	0.462
DOC_MAPK_gen_1	374	381	PF00069	0.451
DOC_MAPK_gen_1	470	479	PF00069	0.403
DOC_MAPK_gen_1	889	898	PF00069	0.380
DOC_MAPK_HePTP_8	888	900	PF00069	0.466
DOC_MAPK_MEF2A_6	207	215	PF00069	0.451
DOC_MAPK_MEF2A_6	374	383	PF00069	0.451
DOC_MAPK_MEF2A_6	470	479	PF00069	0.462
DOC_MAPK_MEF2A_6	757	766	PF00069	0.544
DOC_MAPK_MEF2A_6	889	898	PF00069	0.387
DOC_PP1_RVXF_1	311	317	PF00149	0.451
DOC_PP1_RVXF_1	323	329	PF00149	0.451
DOC_PP2B_LxvP_1	477	480	PF13499	0.462
DOC_PP2B_LxvP_1	615	618	PF13499	0.426
DOC_USP7_MATH_1	139	143	PF00917	0.614
DOC_USP7_MATH_1	252	256	PF00917	0.564
DOC_USP7_MATH_1	305	309	PF00917	0.552
DOC_USP7_MATH_1	511	515	PF00917	0.451
DOC_USP7_MATH_1	770	774	PF00917	0.657
DOC_USP7_MATH_1	848	852	PF00917	0.569
DOC_USP7_MATH_1	913	917	PF00917	0.429
DOC_USP7_MATH_1	99	103	PF00917	0.765
DOC_WW_Pin1_4	101	106	PF00397	0.726
DOC_WW_Pin1_4	245	250	PF00397	0.526
DOC_WW_Pin1_4	870	875	PF00397	0.734
LIG_14-3-3_CanoR_1	138	148	PF00244	0.725
LIG_14-3-3_CanoR_1	190	194	PF00244	0.424
LIG_14-3-3_CanoR_1	244	249	PF00244	0.500
LIG_14-3-3_CanoR_1	280	286	PF00244	0.475
LIG_14-3-3_CanoR_1	358	368	PF00244	0.453
LIG_14-3-3_CanoR_1	559	565	PF00244	0.461
LIG_14-3-3_CanoR_1	570	577	PF00244	0.244
LIG_14-3-3_CanoR_1	591	601	PF00244	0.345
LIG_14-3-3_CanoR_1	641	645	PF00244	0.458
LIG_14-3-3_CanoR_1	87	95	PF00244	0.706
LIG_14-3-3_CanoR_1	901	908	PF00244	0.482
LIG_Actin_WH2_2	357	372	PF00022	0.451
LIG_Actin_WH2_2	711	728	PF00022	0.406
LIG_AP2alpha_1	393	397	PF02296	0.465
LIG_BRCT_BRCA1_1	393	397	PF00533	0.364
LIG_BRCT_BRCA1_1	65	69	PF00533	0.669
LIG_BRCT_BRCA1_1	808	812	PF00533	0.382
LIG_BRCT_BRCA1_1	858	862	PF00533	0.421
LIG_BRCT_BRCA1_2	393	399	PF00533	0.511
LIG_Clathr_ClatBox_1	609	613	PF01394	0.380
LIG_FHA_1	221	227	PF00498	0.459
LIG_FHA_1	318	324	PF00498	0.466
LIG_FHA_1	360	366	PF00498	0.475
LIG_FHA_1	407	413	PF00498	0.418
LIG_FHA_1	499	505	PF00498	0.459
LIG_FHA_1	618	624	PF00498	0.420
LIG_FHA_1	713	719	PF00498	0.454
LIG_FHA_1	802	808	PF00498	0.327
LIG_FHA_1	856	862	PF00498	0.460
LIG_FHA_2	165	171	PF00498	0.513
LIG_FHA_2	29	35	PF00498	0.637
LIG_FHA_2	455	461	PF00498	0.525
LIG_FHA_2	48	54	PF00498	0.294
LIG_FHA_2	583	589	PF00498	0.391
LIG_FHA_2	62	68	PF00498	0.627
LIG_FHA_2	876	882	PF00498	0.697
LIG_LIR_Apic_2	532	536	PF02991	0.491
LIG_LIR_Gen_1	142	153	PF02991	0.579
LIG_LIR_Gen_1	165	176	PF02991	0.626
LIG_LIR_Gen_1	391	401	PF02991	0.497
LIG_LIR_Gen_1	715	725	PF02991	0.465
LIG_LIR_Gen_1	758	766	PF02991	0.507
LIG_LIR_Gen_1	821	831	PF02991	0.422
LIG_LIR_Gen_1	86	96	PF02991	0.690
LIG_LIR_LC3C_4	824	828	PF02991	0.442
LIG_LIR_Nem_3	165	171	PF02991	0.620
LIG_LIR_Nem_3	391	396	PF02991	0.494
LIG_LIR_Nem_3	567	572	PF02991	0.382
LIG_LIR_Nem_3	715	720	PF02991	0.400
LIG_LIR_Nem_3	758	762	PF02991	0.492
LIG_LIR_Nem_3	809	815	PF02991	0.348
LIG_LIR_Nem_3	821	826	PF02991	0.384
LIG_LIR_Nem_3	86	91	PF02991	0.721
LIG_MLH1_MIPbox_1	393	397	PF16413	0.379
LIG_MLH1_MIPbox_1	808	812	PF16413	0.382
LIG_NRBOX	364	370	PF00104	0.451
LIG_PCNA_yPIPBox_3	711	719	PF02747	0.353
LIG_PCNA_yPIPBox_3	778	791	PF02747	0.483
LIG_Pex14_2	393	397	PF04695	0.345
LIG_REV1ctd_RIR_1	394	400	PF16727	0.485
LIG_SH2_GRB2like	533	536	PF00017	0.491
LIG_SH2_PTP2	717	720	PF00017	0.344
LIG_SH2_SRC	231	234	PF00017	0.511
LIG_SH2_STAP1	494	498	PF00017	0.403
LIG_SH2_STAT3	534	537	PF00017	0.511
LIG_SH2_STAT5	145	148	PF00017	0.590
LIG_SH2_STAT5	162	165	PF00017	0.445
LIG_SH2_STAT5	229	232	PF00017	0.475
LIG_SH2_STAT5	424	427	PF00017	0.388
LIG_SH2_STAT5	522	525	PF00017	0.451
LIG_SH2_STAT5	575	578	PF00017	0.418
LIG_SH2_STAT5	717	720	PF00017	0.344
LIG_SH2_STAT5	825	828	PF00017	0.368
LIG_SH2_STAT5	928	931	PF00017	0.422
LIG_SH3_3	121	127	PF00018	0.665
LIG_SH3_3	299	305	PF00018	0.537
LIG_SH3_3	444	450	PF00018	0.472
LIG_SH3_3	650	656	PF00018	0.451
LIG_SH3_3	824	830	PF00018	0.477
LIG_SH3_3	93	99	PF00018	0.714
LIG_SH3_5	420	424	PF00018	0.402
LIG_SUMO_SIM_par_1	211	218	PF11976	0.452
LIG_SUMO_SIM_par_1	679	685	PF11976	0.475
LIG_TRAF2_1	198	201	PF00917	0.501
LIG_TRAF2_1	271	274	PF00917	0.395
LIG_TRFH_1	235	239	PF08558	0.537
LIG_TRFH_1	652	656	PF08558	0.511
LIG_UBA3_1	630	637	PF00899	0.454
LIG_WRC_WIRS_1	756	761	PF05994	0.470
MOD_CK1_1	101	107	PF00069	0.595
MOD_CK1_1	220	226	PF00069	0.451
MOD_CK1_1	359	365	PF00069	0.459
MOD_CK1_1	406	412	PF00069	0.527
MOD_CK1_1	428	434	PF00069	0.440
MOD_CK1_1	549	555	PF00069	0.441
MOD_CK1_1	619	625	PF00069	0.409
MOD_CK1_1	834	840	PF00069	0.611
MOD_CK1_1	844	850	PF00069	0.605
MOD_CK1_1	875	881	PF00069	0.665
MOD_CK2_1	146	152	PF00069	0.540
MOD_CK2_1	164	170	PF00069	0.418
MOD_CK2_1	28	34	PF00069	0.597
MOD_CK2_1	290	296	PF00069	0.451
MOD_CK2_1	45	51	PF00069	0.328
MOD_CK2_1	454	460	PF00069	0.512
MOD_CK2_1	582	588	PF00069	0.397
MOD_CK2_1	61	67	PF00069	0.510
MOD_CK2_1	698	704	PF00069	0.564
MOD_CK2_1	848	854	PF00069	0.512
MOD_CK2_1	875	881	PF00069	0.721
MOD_Cter_Amidation	645	648	PF01082	0.275
MOD_Cter_Amidation	864	867	PF01082	0.595
MOD_GlcNHglycan	101	104	PF01048	0.555
MOD_GlcNHglycan	124	127	PF01048	0.723
MOD_GlcNHglycan	128	131	PF01048	0.707
MOD_GlcNHglycan	141	144	PF01048	0.634
MOD_GlcNHglycan	219	222	PF01048	0.251
MOD_GlcNHglycan	384	387	PF01048	0.251
MOD_GlcNHglycan	405	408	PF01048	0.574
MOD_GlcNHglycan	427	430	PF01048	0.419
MOD_GlcNHglycan	551	554	PF01048	0.251
MOD_GlcNHglycan	58	61	PF01048	0.604
MOD_GlcNHglycan	594	597	PF01048	0.459
MOD_GlcNHglycan	700	703	PF01048	0.449
MOD_GlcNHglycan	791	794	PF01048	0.636
MOD_GlcNHglycan	808	811	PF01048	0.252
MOD_GlcNHglycan	843	846	PF01048	0.674
MOD_GlcNHglycan	874	877	PF01048	0.499
MOD_GlcNHglycan	915	918	PF01048	0.465
MOD_GlcNHglycan	922	925	PF01048	0.418
MOD_GSK3_1	109	116	PF00069	0.755
MOD_GSK3_1	122	129	PF00069	0.716
MOD_GSK3_1	134	141	PF00069	0.683
MOD_GSK3_1	217	224	PF00069	0.451
MOD_GSK3_1	317	324	PF00069	0.481
MOD_GSK3_1	454	461	PF00069	0.512
MOD_GSK3_1	494	501	PF00069	0.528
MOD_GSK3_1	545	552	PF00069	0.488
MOD_GSK3_1	768	775	PF00069	0.692
MOD_GSK3_1	830	837	PF00069	0.591
MOD_GSK3_1	844	851	PF00069	0.491
MOD_GSK3_1	870	877	PF00069	0.611
MOD_GSK3_1	909	916	PF00069	0.386
MOD_GSK3_1	94	101	PF00069	0.751
MOD_LATS_1	356	362	PF00433	0.556
MOD_NEK2_1	133	138	PF00069	0.657
MOD_NEK2_1	281	286	PF00069	0.451
MOD_NEK2_1	403	408	PF00069	0.495
MOD_NEK2_1	435	440	PF00069	0.393
MOD_NEK2_1	590	595	PF00069	0.361
MOD_NEK2_1	642	647	PF00069	0.451
MOD_NEK2_1	734	739	PF00069	0.372
MOD_NEK2_1	831	836	PF00069	0.657
MOD_NEK2_1	900	905	PF00069	0.486
MOD_PIKK_1	20	26	PF00454	0.604
MOD_PIKK_1	221	227	PF00454	0.451
MOD_PIKK_1	281	287	PF00454	0.464
MOD_PIKK_1	546	552	PF00454	0.455
MOD_PIKK_1	560	566	PF00454	0.410
MOD_PKA_1	901	907	PF00069	0.554
MOD_PKA_2	189	195	PF00069	0.421
MOD_PKA_2	590	596	PF00069	0.377
MOD_PKA_2	640	646	PF00069	0.458
MOD_PKA_2	86	92	PF00069	0.698
MOD_PKA_2	865	871	PF00069	0.655
MOD_PKA_2	900	906	PF00069	0.453
MOD_PKB_1	242	250	PF00069	0.500
MOD_Plk_1	164	170	PF00069	0.589
MOD_Plk_1	342	348	PF00069	0.501
MOD_Plk_1	356	362	PF00069	0.388
MOD_Plk_1	494	500	PF00069	0.525
MOD_Plk_1	511	517	PF00069	0.427
MOD_Plk_1	831	837	PF00069	0.527
MOD_Plk_1	848	854	PF00069	0.554
MOD_Plk_4	28	34	PF00069	0.624
MOD_Plk_4	305	311	PF00069	0.491
MOD_Plk_4	428	434	PF00069	0.447
MOD_Plk_4	461	467	PF00069	0.568
MOD_Plk_4	682	688	PF00069	0.452
MOD_Plk_4	856	862	PF00069	0.391
MOD_ProDKin_1	101	107	PF00069	0.728
MOD_ProDKin_1	245	251	PF00069	0.526
MOD_ProDKin_1	870	876	PF00069	0.737
MOD_SUMO_for_1	258	261	PF00179	0.486
MOD_SUMO_for_1	816	819	PF00179	0.498
MOD_SUMO_rev_2	771	780	PF00179	0.718
TRG_AP2beta_CARGO_1	165	175	PF09066	0.631
TRG_DiLeu_BaEn_1	201	206	PF01217	0.499
TRG_DiLeu_BaEn_1	277	282	PF01217	0.525
TRG_DiLeu_BaEn_1	51	56	PF01217	0.600
TRG_DiLeu_BaEn_1	890	895	PF01217	0.372
TRG_DiLeu_BaEn_4	232	238	PF01217	0.537
TRG_DiLeu_BaLyEn_6	241	246	PF01217	0.500
TRG_DiLeu_BaLyEn_6	472	477	PF01217	0.491
TRG_DiLeu_LyEn_5	277	282	PF01217	0.525
TRG_ENDOCYTIC_2	145	148	PF00928	0.597
TRG_ENDOCYTIC_2	482	485	PF00928	0.444
TRG_ENDOCYTIC_2	569	572	PF00928	0.436
TRG_ENDOCYTIC_2	717	720	PF00928	0.344
TRG_ENDOCYTIC_2	825	828	PF00928	0.402
TRG_ER_diArg_1	242	245	PF00400	0.462
TRG_ER_diArg_1	286	288	PF00400	0.462
TRG_ER_diArg_1	373	375	PF00400	0.465
TRG_ER_diArg_1	472	475	PF00400	0.564
TRG_ER_diArg_1	6	8	PF00400	0.599
TRG_ER_diArg_1	647	649	PF00400	0.475
TRG_ER_diArg_1	73	75	PF00400	0.624
TRG_ER_diArg_1	746	749	PF00400	0.388
TRG_ER_diArg_1	900	902	PF00400	0.571
TRG_ER_diArg_1	938	941	PF00400	0.637
TRG_NES_CRM1_1	588	600	PF08389	0.371
TRG_NLS_MonoExtC_3	938	943	PF00514	0.642
TRG_NLS_MonoExtN_4	239	246	PF00514	0.522
TRG_NLS_MonoExtN_4	939	944	PF00514	0.681
TRG_Pf-PMV_PEXEL_1	358	363	PF00026	0.262
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5V0	Leptomonas seymouri	36%	100%
A0A0N0P8Y1	Leptomonas seymouri	35%	100%
A0A0N0P9D2	Leptomonas seymouri	37%	100%
A0A0N1I0Z0	Leptomonas seymouri	35%	87%
A0A0N1PEU4	Leptomonas seymouri	74%	99%
A0A0S4IQ76	Bodo saltans	34%	100%
A0A0S4IR78	Bodo saltans	48%	100%
A0A0S4IS51	Bodo saltans	35%	100%
A0A0S4ITR4	Bodo saltans	36%	88%
A0A0S4IWU8	Bodo saltans	48%	100%
A0A0S4J157	Bodo saltans	37%	100%
A0A0S4JCY8	Bodo saltans	35%	92%
A0A1X0NJ46	Trypanosomatidae	36%	100%
A0A1X0NKY7	Trypanosomatidae	36%	88%
A0A1X0NUZ7	Trypanosomatidae	31%	72%
A0A1X0NVG5	Trypanosomatidae	37%	88%
A0A1X0P0D7	Trypanosomatidae	36%	100%
A0A1X0P872	Trypanosomatidae	59%	100%
A0A1X0P9K6	Trypanosomatidae	36%	100%
A0A3Q8II71	Leishmania donovani	36%	100%
A0A3Q8IJ24	Leishmania donovani	99%	100%
A0A3Q8IWG4	Leishmania donovani	36%	100%
A0A3R7MA90	Trypanosoma rangeli	36%	100%
A0A3R7MLF0	Trypanosoma rangeli	29%	67%
A0A3R7NT42	Trypanosoma rangeli	36%	100%
A0A3S7WYA1	Leishmania donovani	34%	87%
A0A3S7X8Z5	Leishmania donovani	36%	100%
A0A3S7XB01	Leishmania donovani	35%	87%
A0A422MXB1	Trypanosoma rangeli	36%	89%
A0A422N8L3	Trypanosoma rangeli	33%	93%
A1Z9L3	Drosophila melanogaster	39%	76%
A2A4P0	Mus musculus	39%	76%
A4HAT8	Leishmania braziliensis	35%	100%
A4HME2	Leishmania braziliensis	36%	93%
A4HNU7	Leishmania braziliensis	87%	100%
A4HPE9	Leishmania braziliensis	35%	100%
A4HQ83	Leishmania braziliensis	36%	90%
A4I0U7	Leishmania infantum	34%	100%
A4IA06	Leishmania infantum	36%	100%
A4IB14	Leishmania infantum	36%	93%
A4ICJ0	Leishmania infantum	35%	100%
A4IDY1	Leishmania infantum	36%	100%
B0XDC4	Culex quinquefasciatus	29%	68%
B8A4F4	Danio rerio	30%	70%
C9ZMN0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZNP6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A2R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
D0A3F8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	89%
D0A429	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
D0A778	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	90%
E9AEU3	Leishmania major	36%	93%
E9ASK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9AT60	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9AU01	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	90%
E9B512	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B5Z9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	93%
F4IE66	Arabidopsis thaliana	34%	100%
F4IJV4	Arabidopsis thaliana	40%	90%
F4JMJ3	Arabidopsis thaliana	37%	100%
F4JRJ6	Arabidopsis thaliana	36%	100%
F4K2E9	Arabidopsis thaliana	35%	75%
O22899	Arabidopsis thaliana	35%	100%
O35286	Mus musculus	36%	100%
O42643	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	81%
O42945	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
O43143	Homo sapiens	36%	100%
O45244	Caenorhabditis elegans	39%	94%
O60231	Homo sapiens	37%	91%
P15938	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	88%
P20095	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P24384	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	82%
P34498	Caenorhabditis elegans	37%	83%
P36009	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P43329	Escherichia coli (strain K12)	33%	73%
P45018	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	32%	72%
P53131	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
Q03319	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
Q09530	Caenorhabditis elegans	39%	79%
Q10752	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	89%
Q14562	Homo sapiens	39%	77%
Q14BI7	Mus musculus	27%	68%
Q17R09	Bos taurus	36%	77%
Q20875	Caenorhabditis elegans	34%	100%
Q38953	Arabidopsis thaliana	39%	81%
Q3ZBE0	Bos taurus	30%	100%
Q4Q0J4	Leishmania major	36%	90%
Q4Q1D7	Leishmania major	35%	100%
Q4Q1Y9	Leishmania major	95%	100%
Q4Q2X4	Leishmania major	36%	100%
Q54F05	Dictyostelium discoideum	38%	81%
Q54MH3	Dictyostelium discoideum	40%	85%
Q54NJ4	Dictyostelium discoideum	38%	100%
Q5BJS0	Rattus norvegicus	31%	79%
Q5R864	Pongo abelii	35%	100%
Q5RAZ4	Pongo abelii	36%	100%
Q5RBD4	Pongo abelii	37%	100%
Q5XH12	Xenopus laevis	27%	100%
Q5XI69	Rattus norvegicus	35%	100%
Q68FK8	Xenopus laevis	30%	75%
Q6PE54	Mus musculus	35%	100%
Q767K6	Sus scrofa	36%	90%
Q7K3M5	Drosophila melanogaster	35%	100%
Q7L7V1	Homo sapiens	25%	100%
Q7YR39	Pan troglodytes	37%	90%
Q80VY9	Mus musculus	33%	100%
Q8BZS9	Mus musculus	26%	100%
Q8IX18	Homo sapiens	35%	100%
Q8TE96	Homo sapiens	30%	100%
Q8VHK9	Mus musculus	27%	94%
Q8VY00	Arabidopsis thaliana	40%	90%
Q924H9	Mus musculus	30%	100%
Q92620	Homo sapiens	36%	77%
Q99PU8	Mus musculus	31%	78%
Q9C6G0	Arabidopsis thaliana	31%	67%
Q9H5Z1	Homo sapiens	37%	100%
Q9H6R0	Homo sapiens	34%	100%
Q9HDY4	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	80%
Q9HE06	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
Q9LZQ9	Arabidopsis thaliana	36%	100%
V5B3L7	Trypanosoma cruzi	35%	100%
V5B7H6	Trypanosoma cruzi	31%	86%
V5BKH2	Trypanosoma cruzi	38%	100%
V5BND8	Trypanosoma cruzi	29%	67%
V5BPV3	Trypanosoma cruzi	36%	89%
V5BV22	Trypanosoma cruzi	56%	100%
V5C0I9	Trypanosoma cruzi	35%	100%
V5D886	Trypanosoma cruzi	36%	100%