LeishMANIAdb
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Guanylate cyclase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Guanylate cyclase
Gene product:
mitogen-activated protein kinase-like protein
Species:
Leishmania infantum
UniProt:
A4ICP3_LEIIN
TriTrypDb:
LINF_360014800
Length:
1563

Annotations

Annotations by Jardim et al.

Protein kinase, Mitogen-activated kinase-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

A4ICP3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICP3

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 7
GO:0006163 purine nucleotide metabolic process 5 7
GO:0006164 purine nucleotide biosynthetic process 6 7
GO:0006171 cAMP biosynthetic process 8 7
GO:0006182 cGMP biosynthetic process 8 7
GO:0006468 protein phosphorylation 5 7
GO:0006725 cellular aromatic compound metabolic process 3 7
GO:0006753 nucleoside phosphate metabolic process 4 7
GO:0006793 phosphorus metabolic process 3 7
GO:0006796 phosphate-containing compound metabolic process 4 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
GO:0009058 biosynthetic process 2 7
GO:0009117 nucleotide metabolic process 5 7
GO:0009150 purine ribonucleotide metabolic process 6 7
GO:0009152 purine ribonucleotide biosynthetic process 7 7
GO:0009165 nucleotide biosynthetic process 6 7
GO:0009187 cyclic nucleotide metabolic process 6 7
GO:0009190 cyclic nucleotide biosynthetic process 7 7
GO:0009259 ribonucleotide metabolic process 5 7
GO:0009260 ribonucleotide biosynthetic process 6 7
GO:0009987 cellular process 1 7
GO:0016310 phosphorylation 5 7
GO:0018130 heterocycle biosynthetic process 4 7
GO:0019438 aromatic compound biosynthetic process 4 7
GO:0019538 protein metabolic process 3 7
GO:0019637 organophosphate metabolic process 3 7
GO:0019693 ribose phosphate metabolic process 4 7
GO:0034641 cellular nitrogen compound metabolic process 3 7
GO:0034654 nucleobase-containing compound biosynthetic process 4 7
GO:0036211 protein modification process 4 7
GO:0043170 macromolecule metabolic process 3 7
GO:0043412 macromolecule modification 4 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0044249 cellular biosynthetic process 3 7
GO:0044271 cellular nitrogen compound biosynthetic process 4 7
GO:0044281 small molecule metabolic process 2 7
GO:0046058 cAMP metabolic process 7 7
GO:0046068 cGMP metabolic process 7 7
GO:0046390 ribose phosphate biosynthetic process 5 7
GO:0046483 heterocycle metabolic process 3 7
GO:0052652 cyclic purine nucleotide metabolic process 6 7
GO:0055086 nucleobase-containing small molecule metabolic process 3 7
GO:0071704 organic substance metabolic process 2 7
GO:0072521 purine-containing compound metabolic process 4 7
GO:0072522 purine-containing compound biosynthetic process 5 7
GO:0090407 organophosphate biosynthetic process 4 7
GO:1901135 carbohydrate derivative metabolic process 3 7
GO:1901137 carbohydrate derivative biosynthetic process 4 7
GO:1901293 nucleoside phosphate biosynthetic process 5 7
GO:1901360 organic cyclic compound metabolic process 3 7
GO:1901362 organic cyclic compound biosynthetic process 4 7
GO:1901564 organonitrogen compound metabolic process 3 7
GO:1901566 organonitrogen compound biosynthetic process 4 7
GO:1901576 organic substance biosynthetic process 3 7
GO:0007165 signal transduction 2 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0065007 biological regulation 1 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004672 protein kinase activity 3 7
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016301 kinase activity 4 7
GO:0016740 transferase activity 2 7
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 7
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140096 catalytic activity, acting on a protein 2 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1143 1147 PF00656 0.744
CLV_C14_Caspase3-7 1448 1452 PF00656 0.524
CLV_C14_Caspase3-7 196 200 PF00656 0.605
CLV_C14_Caspase3-7 777 781 PF00656 0.610
CLV_MEL_PAP_1 545 551 PF00089 0.530
CLV_MEL_PAP_1 560 566 PF00089 0.527
CLV_NRD_NRD_1 102 104 PF00675 0.488
CLV_NRD_NRD_1 1089 1091 PF00675 0.479
CLV_NRD_NRD_1 1209 1211 PF00675 0.481
CLV_NRD_NRD_1 1398 1400 PF00675 0.279
CLV_NRD_NRD_1 1551 1553 PF00675 0.309
CLV_NRD_NRD_1 172 174 PF00675 0.524
CLV_NRD_NRD_1 24 26 PF00675 0.462
CLV_NRD_NRD_1 290 292 PF00675 0.568
CLV_NRD_NRD_1 432 434 PF00675 0.553
CLV_NRD_NRD_1 63 65 PF00675 0.497
CLV_NRD_NRD_1 67 69 PF00675 0.510
CLV_NRD_NRD_1 962 964 PF00675 0.417
CLV_NRD_NRD_1 971 973 PF00675 0.390
CLV_NRD_NRD_1 980 982 PF00675 0.301
CLV_NRD_NRD_1 998 1000 PF00675 0.360
CLV_PCSK_KEX2_1 1027 1029 PF00082 0.503
CLV_PCSK_KEX2_1 1089 1091 PF00082 0.491
CLV_PCSK_KEX2_1 1209 1211 PF00082 0.481
CLV_PCSK_KEX2_1 1551 1553 PF00082 0.309
CLV_PCSK_KEX2_1 171 173 PF00082 0.540
CLV_PCSK_KEX2_1 432 434 PF00082 0.644
CLV_PCSK_KEX2_1 534 536 PF00082 0.648
CLV_PCSK_KEX2_1 638 640 PF00082 0.413
CLV_PCSK_KEX2_1 67 69 PF00082 0.503
CLV_PCSK_KEX2_1 962 964 PF00082 0.417
CLV_PCSK_KEX2_1 971 973 PF00082 0.399
CLV_PCSK_KEX2_1 980 982 PF00082 0.496
CLV_PCSK_KEX2_1 998 1000 PF00082 0.398
CLV_PCSK_PC1ET2_1 1027 1029 PF00082 0.501
CLV_PCSK_PC1ET2_1 534 536 PF00082 0.648
CLV_PCSK_PC1ET2_1 638 640 PF00082 0.413
CLV_PCSK_PC7_1 994 1000 PF00082 0.365
CLV_PCSK_SKI1_1 109 113 PF00082 0.446
CLV_PCSK_SKI1_1 1151 1155 PF00082 0.560
CLV_PCSK_SKI1_1 1447 1451 PF00082 0.233
CLV_PCSK_SKI1_1 256 260 PF00082 0.562
CLV_PCSK_SKI1_1 278 282 PF00082 0.560
CLV_PCSK_SKI1_1 531 535 PF00082 0.648
CLV_PCSK_SKI1_1 570 574 PF00082 0.484
CLV_PCSK_SKI1_1 641 645 PF00082 0.375
CLV_PCSK_SKI1_1 654 658 PF00082 0.413
CLV_PCSK_SKI1_1 677 681 PF00082 0.418
CLV_PCSK_SKI1_1 943 947 PF00082 0.396
DEG_APCC_DBOX_1 1088 1096 PF00400 0.781
DEG_APCC_DBOX_1 277 285 PF00400 0.350
DEG_MDM2_SWIB_1 307 315 PF02201 0.323
DEG_SCF_FBW7_1 1455 1462 PF00400 0.524
DEG_SPOP_SBC_1 1180 1184 PF00917 0.652
DEG_SPOP_SBC_1 2 6 PF00917 0.674
DOC_CYCLIN_yCln2_LP_2 1174 1177 PF00134 0.686
DOC_MAPK_gen_1 1399 1407 PF00069 0.483
DOC_MAPK_gen_1 208 217 PF00069 0.636
DOC_MAPK_gen_1 291 298 PF00069 0.421
DOC_MAPK_gen_1 463 472 PF00069 0.356
DOC_MAPK_gen_1 758 766 PF00069 0.516
DOC_MAPK_gen_1 837 845 PF00069 0.525
DOC_MAPK_HePTP_8 209 221 PF00069 0.524
DOC_MAPK_MEF2A_6 210 219 PF00069 0.538
DOC_MAPK_MEF2A_6 587 595 PF00069 0.314
DOC_MAPK_MEF2A_6 760 768 PF00069 0.513
DOC_MAPK_MEF2A_6 839 847 PF00069 0.503
DOC_PP1_RVXF_1 999 1005 PF00149 0.646
DOC_PP2B_LxvP_1 1174 1177 PF13499 0.664
DOC_PP2B_LxvP_1 303 306 PF13499 0.378
DOC_PP2B_LxvP_1 50 53 PF13499 0.642
DOC_PP2B_LxvP_1 697 700 PF13499 0.618
DOC_PP2B_LxvP_1 90 93 PF13499 0.645
DOC_PP4_FxxP_1 1461 1464 PF00568 0.487
DOC_PP4_FxxP_1 32 35 PF00568 0.688
DOC_PP4_FxxP_1 816 819 PF00568 0.574
DOC_USP7_MATH_1 102 106 PF00917 0.686
DOC_USP7_MATH_1 1034 1038 PF00917 0.682
DOC_USP7_MATH_1 1094 1098 PF00917 0.701
DOC_USP7_MATH_1 1123 1127 PF00917 0.735
DOC_USP7_MATH_1 1140 1144 PF00917 0.639
DOC_USP7_MATH_1 122 126 PF00917 0.645
DOC_USP7_MATH_1 1256 1260 PF00917 0.707
DOC_USP7_MATH_1 2 6 PF00917 0.691
DOC_USP7_MATH_1 775 779 PF00917 0.642
DOC_USP7_UBL2_3 100 104 PF12436 0.632
DOC_USP7_UBL2_3 459 463 PF12436 0.325
DOC_USP7_UBL2_3 943 947 PF12436 0.571
DOC_WW_Pin1_4 1119 1124 PF00397 0.809
DOC_WW_Pin1_4 1181 1186 PF00397 0.758
DOC_WW_Pin1_4 1220 1225 PF00397 0.725
DOC_WW_Pin1_4 141 146 PF00397 0.743
DOC_WW_Pin1_4 1455 1460 PF00397 0.527
DOC_WW_Pin1_4 491 496 PF00397 0.437
DOC_WW_Pin1_4 933 938 PF00397 0.648
DOC_WW_Pin1_4 971 976 PF00397 0.571
LIG_14-3-3_CanoR_1 103 112 PF00244 0.752
LIG_14-3-3_CanoR_1 1031 1037 PF00244 0.682
LIG_14-3-3_CanoR_1 1127 1135 PF00244 0.659
LIG_14-3-3_CanoR_1 1293 1298 PF00244 0.541
LIG_14-3-3_CanoR_1 1447 1455 PF00244 0.504
LIG_14-3-3_CanoR_1 1460 1464 PF00244 0.459
LIG_14-3-3_CanoR_1 1513 1517 PF00244 0.524
LIG_14-3-3_CanoR_1 203 207 PF00244 0.609
LIG_14-3-3_CanoR_1 278 284 PF00244 0.354
LIG_14-3-3_CanoR_1 285 289 PF00244 0.340
LIG_14-3-3_CanoR_1 639 644 PF00244 0.655
LIG_14-3-3_CanoR_1 654 662 PF00244 0.569
LIG_14-3-3_CanoR_1 67 75 PF00244 0.732
LIG_14-3-3_CanoR_1 758 766 PF00244 0.523
LIG_APCC_ABBA_1 360 365 PF00400 0.310
LIG_APCC_ABBA_1 553 558 PF00400 0.276
LIG_APCC_ABBA_1 909 914 PF00400 0.565
LIG_BIR_III_4 445 449 PF00653 0.269
LIG_BRCT_BRCA1_1 1096 1100 PF00533 0.692
LIG_BRCT_BRCA1_1 1182 1186 PF00533 0.663
LIG_BRCT_BRCA1_1 446 450 PF00533 0.330
LIG_BRCT_BRCA1_1 468 472 PF00533 0.296
LIG_BRCT_BRCA1_1 688 692 PF00533 0.669
LIG_deltaCOP1_diTrp_1 309 316 PF00928 0.355
LIG_deltaCOP1_diTrp_1 451 457 PF00928 0.387
LIG_deltaCOP1_diTrp_1 747 756 PF00928 0.595
LIG_EH1_1 921 929 PF00400 0.539
LIG_eIF4E_1 1401 1407 PF01652 0.475
LIG_FHA_1 1036 1042 PF00498 0.726
LIG_FHA_1 1196 1202 PF00498 0.831
LIG_FHA_1 13 19 PF00498 0.720
LIG_FHA_1 1303 1309 PF00498 0.612
LIG_FHA_1 1322 1328 PF00498 0.390
LIG_FHA_1 1432 1438 PF00498 0.473
LIG_FHA_1 1448 1454 PF00498 0.473
LIG_FHA_1 300 306 PF00498 0.351
LIG_FHA_1 321 327 PF00498 0.333
LIG_FHA_1 426 432 PF00498 0.342
LIG_FHA_1 520 526 PF00498 0.326
LIG_FHA_1 544 550 PF00498 0.394
LIG_FHA_1 569 575 PF00498 0.403
LIG_FHA_1 760 766 PF00498 0.491
LIG_FHA_1 890 896 PF00498 0.556
LIG_FHA_2 1496 1502 PF00498 0.491
LIG_FHA_2 1552 1558 PF00498 0.473
LIG_FHA_2 403 409 PF00498 0.479
LIG_FHA_2 6 12 PF00498 0.658
LIG_FHA_2 655 661 PF00498 0.612
LIG_FHA_2 855 861 PF00498 0.608
LIG_LIR_Apic_2 1287 1291 PF02991 0.588
LIG_LIR_Apic_2 1458 1464 PF02991 0.488
LIG_LIR_Apic_2 29 35 PF02991 0.681
LIG_LIR_Apic_2 814 819 PF02991 0.580
LIG_LIR_Apic_2 97 102 PF02991 0.677
LIG_LIR_Gen_1 1316 1323 PF02991 0.589
LIG_LIR_Gen_1 325 335 PF02991 0.406
LIG_LIR_Gen_1 340 351 PF02991 0.269
LIG_LIR_Gen_1 451 461 PF02991 0.433
LIG_LIR_Gen_1 551 560 PF02991 0.322
LIG_LIR_Gen_1 588 598 PF02991 0.291
LIG_LIR_Gen_1 665 673 PF02991 0.576
LIG_LIR_Gen_1 804 812 PF02991 0.520
LIG_LIR_LC3C_4 761 766 PF02991 0.550
LIG_LIR_Nem_3 1057 1061 PF02991 0.727
LIG_LIR_Nem_3 1103 1109 PF02991 0.674
LIG_LIR_Nem_3 1313 1317 PF02991 0.477
LIG_LIR_Nem_3 1368 1374 PF02991 0.473
LIG_LIR_Nem_3 301 307 PF02991 0.362
LIG_LIR_Nem_3 340 346 PF02991 0.284
LIG_LIR_Nem_3 408 412 PF02991 0.326
LIG_LIR_Nem_3 451 457 PF02991 0.427
LIG_LIR_Nem_3 551 555 PF02991 0.340
LIG_LIR_Nem_3 558 562 PF02991 0.351
LIG_LIR_Nem_3 588 593 PF02991 0.469
LIG_LIR_Nem_3 665 669 PF02991 0.577
LIG_LIR_Nem_3 747 752 PF02991 0.598
LIG_LIR_Nem_3 804 808 PF02991 0.535
LIG_LIR_Nem_3 849 854 PF02991 0.523
LIG_LIR_Nem_3 944 949 PF02991 0.580
LIG_MLH1_MIPbox_1 446 450 PF16413 0.330
LIG_NRBOX 1557 1563 PF00104 0.601
LIG_NRBOX 216 222 PF00104 0.381
LIG_PCNA_yPIPBox_3 432 441 PF02747 0.396
LIG_Pex14_1 453 457 PF04695 0.332
LIG_Pex14_2 307 311 PF04695 0.315
LIG_Pex14_2 449 453 PF04695 0.314
LIG_Pex14_2 812 816 PF04695 0.570
LIG_PTB_Apo_2 236 243 PF02174 0.390
LIG_PTB_Apo_2 660 667 PF02174 0.662
LIG_PTB_Phospho_1 236 242 PF10480 0.391
LIG_REV1ctd_RIR_1 447 456 PF16727 0.348
LIG_SH2_CRK 1288 1292 PF00017 0.588
LIG_SH2_CRK 242 246 PF00017 0.375
LIG_SH2_CRK 391 395 PF00017 0.340
LIG_SH2_CRK 577 581 PF00017 0.316
LIG_SH2_CRK 851 855 PF00017 0.529
LIG_SH2_CRK 932 936 PF00017 0.636
LIG_SH2_NCK_1 1497 1501 PF00017 0.524
LIG_SH2_PTP2 1318 1321 PF00017 0.474
LIG_SH2_PTP2 393 396 PF00017 0.324
LIG_SH2_PTP2 552 555 PF00017 0.264
LIG_SH2_SRC 250 253 PF00017 0.357
LIG_SH2_SRC 964 967 PF00017 0.504
LIG_SH2_STAP1 1361 1365 PF00017 0.482
LIG_SH2_STAP1 1401 1405 PF00017 0.473
LIG_SH2_STAT3 1411 1414 PF00017 0.499
LIG_SH2_STAT3 997 1000 PF00017 0.639
LIG_SH2_STAT5 1318 1321 PF00017 0.473
LIG_SH2_STAT5 1377 1380 PF00017 0.608
LIG_SH2_STAT5 1411 1414 PF00017 0.503
LIG_SH2_STAT5 1497 1500 PF00017 0.505
LIG_SH2_STAT5 242 245 PF00017 0.411
LIG_SH2_STAT5 250 253 PF00017 0.356
LIG_SH2_STAT5 304 307 PF00017 0.378
LIG_SH2_STAT5 327 330 PF00017 0.415
LIG_SH2_STAT5 393 396 PF00017 0.349
LIG_SH2_STAT5 411 414 PF00017 0.361
LIG_SH2_STAT5 552 555 PF00017 0.379
LIG_SH2_STAT5 853 856 PF00017 0.562
LIG_SH2_STAT5 884 887 PF00017 0.556
LIG_SH2_STAT5 964 967 PF00017 0.500
LIG_SH3_1 972 978 PF00018 0.609
LIG_SH3_2 975 980 PF14604 0.639
LIG_SH3_3 1182 1188 PF00018 0.723
LIG_SH3_3 133 139 PF00018 0.662
LIG_SH3_3 1523 1529 PF00018 0.473
LIG_SH3_3 24 30 PF00018 0.670
LIG_SH3_3 336 342 PF00018 0.387
LIG_SH3_3 346 352 PF00018 0.273
LIG_SH3_3 4 10 PF00018 0.741
LIG_SH3_3 46 52 PF00018 0.702
LIG_SH3_3 489 495 PF00018 0.405
LIG_SH3_3 675 681 PF00018 0.614
LIG_SH3_3 693 699 PF00018 0.659
LIG_SH3_3 72 78 PF00018 0.695
LIG_SH3_3 722 728 PF00018 0.762
LIG_SH3_3 739 745 PF00018 0.589
LIG_SH3_3 931 937 PF00018 0.634
LIG_SH3_3 972 978 PF00018 0.651
LIG_SUMO_SIM_anti_2 1556 1563 PF11976 0.602
LIG_SUMO_SIM_anti_2 261 267 PF11976 0.353
LIG_SUMO_SIM_anti_2 294 302 PF11976 0.325
LIG_SUMO_SIM_anti_2 439 445 PF11976 0.370
LIG_SUMO_SIM_anti_2 761 767 PF11976 0.553
LIG_SUMO_SIM_par_1 1151 1157 PF11976 0.743
LIG_SUMO_SIM_par_1 154 159 PF11976 0.703
LIG_SUMO_SIM_par_1 1556 1563 PF11976 0.602
LIG_SUMO_SIM_par_1 439 445 PF11976 0.337
LIG_SUMO_SIM_par_1 620 626 PF11976 0.576
LIG_SUMO_SIM_par_1 761 767 PF11976 0.502
LIG_SUMO_SIM_par_1 798 804 PF11976 0.594
LIG_TRAF2_1 1554 1557 PF00917 0.473
LIG_WRC_WIRS_1 1477 1482 PF05994 0.335
LIG_WRC_WIRS_1 280 285 PF05994 0.413
LIG_WRC_WIRS_1 520 525 PF05994 0.416
LIG_WRC_WIRS_1 559 564 PF05994 0.395
LIG_WRC_WIRS_1 809 814 PF05994 0.377
LIG_WRPW_2 676 679 PF00400 0.492
LIG_WW_3 485 489 PF00397 0.464
LIG_WW_3 76 80 PF00397 0.582
MOD_CDK_SPK_2 1455 1460 PF00069 0.381
MOD_CK1_1 1023 1029 PF00069 0.580
MOD_CK1_1 1037 1043 PF00069 0.629
MOD_CK1_1 1083 1089 PF00069 0.620
MOD_CK1_1 1098 1104 PF00069 0.493
MOD_CK1_1 1122 1128 PF00069 0.727
MOD_CK1_1 1203 1209 PF00069 0.614
MOD_CK1_1 1254 1260 PF00069 0.639
MOD_CK1_1 1431 1437 PF00069 0.309
MOD_CK1_1 1515 1521 PF00069 0.381
MOD_CK1_1 175 181 PF00069 0.657
MOD_CK1_1 3 9 PF00069 0.694
MOD_CK1_1 322 328 PF00069 0.351
MOD_CK1_1 42 48 PF00069 0.571
MOD_CK1_1 494 500 PF00069 0.482
MOD_CK1_1 626 632 PF00069 0.621
MOD_CK1_1 683 689 PF00069 0.515
MOD_CK1_1 811 817 PF00069 0.435
MOD_CK1_1 877 883 PF00069 0.477
MOD_CK2_1 1067 1073 PF00069 0.684
MOD_CK2_1 1310 1316 PF00069 0.381
MOD_CK2_1 1459 1465 PF00069 0.309
MOD_CK2_1 1551 1557 PF00069 0.309
MOD_CK2_1 188 194 PF00069 0.620
MOD_CK2_1 5 11 PF00069 0.609
MOD_CK2_1 854 860 PF00069 0.477
MOD_CMANNOS 311 314 PF00535 0.456
MOD_Cter_Amidation 289 292 PF01082 0.417
MOD_GlcNHglycan 105 108 PF01048 0.635
MOD_GlcNHglycan 1061 1064 PF01048 0.613
MOD_GlcNHglycan 1141 1145 PF01048 0.649
MOD_GlcNHglycan 1211 1214 PF01048 0.726
MOD_GlcNHglycan 1237 1240 PF01048 0.584
MOD_GlcNHglycan 1244 1247 PF01048 0.538
MOD_GlcNHglycan 1258 1261 PF01048 0.772
MOD_GlcNHglycan 1268 1271 PF01048 0.592
MOD_GlcNHglycan 1461 1464 PF01048 0.325
MOD_GlcNHglycan 1538 1541 PF01048 0.419
MOD_GlcNHglycan 194 199 PF01048 0.538
MOD_GlcNHglycan 252 255 PF01048 0.451
MOD_GlcNHglycan 381 384 PF01048 0.410
MOD_GlcNHglycan 445 449 PF01048 0.347
MOD_GlcNHglycan 657 660 PF01048 0.617
MOD_GlcNHglycan 711 714 PF01048 0.564
MOD_GlcNHglycan 848 851 PF01048 0.370
MOD_GlcNHglycan 994 997 PF01048 0.503
MOD_GSK3_1 1 8 PF00069 0.592
MOD_GSK3_1 1094 1101 PF00069 0.601
MOD_GSK3_1 1107 1114 PF00069 0.563
MOD_GSK3_1 1119 1126 PF00069 0.717
MOD_GSK3_1 1140 1147 PF00069 0.663
MOD_GSK3_1 1176 1183 PF00069 0.642
MOD_GSK3_1 1195 1202 PF00069 0.637
MOD_GSK3_1 1205 1212 PF00069 0.690
MOD_GSK3_1 1226 1233 PF00069 0.598
MOD_GSK3_1 1242 1249 PF00069 0.705
MOD_GSK3_1 1251 1258 PF00069 0.621
MOD_GSK3_1 1319 1326 PF00069 0.379
MOD_GSK3_1 1427 1434 PF00069 0.381
MOD_GSK3_1 1441 1448 PF00069 0.309
MOD_GSK3_1 1451 1458 PF00069 0.328
MOD_GSK3_1 1476 1483 PF00069 0.335
MOD_GSK3_1 279 286 PF00069 0.423
MOD_GSK3_1 310 317 PF00069 0.440
MOD_GSK3_1 322 329 PF00069 0.532
MOD_GSK3_1 623 630 PF00069 0.501
MOD_GSK3_1 686 693 PF00069 0.674
MOD_GSK3_1 698 705 PF00069 0.550
MOD_GSK3_1 734 741 PF00069 0.602
MOD_GSK3_1 885 892 PF00069 0.391
MOD_N-GLC_1 1020 1025 PF02516 0.577
MOD_N-GLC_1 259 264 PF02516 0.401
MOD_N-GLC_1 379 384 PF02516 0.456
MOD_NEK2_1 1032 1037 PF00069 0.674
MOD_NEK2_1 1085 1090 PF00069 0.748
MOD_NEK2_1 1178 1183 PF00069 0.636
MOD_NEK2_1 1205 1210 PF00069 0.633
MOD_NEK2_1 1255 1260 PF00069 0.615
MOD_NEK2_1 1284 1289 PF00069 0.695
MOD_NEK2_1 1302 1307 PF00069 0.350
MOD_NEK2_1 1445 1450 PF00069 0.309
MOD_NEK2_1 1480 1485 PF00069 0.326
MOD_NEK2_1 167 172 PF00069 0.624
MOD_NEK2_1 259 264 PF00069 0.401
MOD_NEK2_1 283 288 PF00069 0.574
MOD_NEK2_1 315 320 PF00069 0.474
MOD_NEK2_1 344 349 PF00069 0.361
MOD_NEK2_1 581 586 PF00069 0.538
MOD_NEK2_1 66 71 PF00069 0.613
MOD_NEK2_1 685 690 PF00069 0.655
MOD_NEK2_1 709 714 PF00069 0.525
MOD_NEK2_1 738 743 PF00069 0.694
MOD_NEK2_1 756 761 PF00069 0.340
MOD_NEK2_1 764 769 PF00069 0.360
MOD_NEK2_1 785 790 PF00069 0.412
MOD_NEK2_1 868 873 PF00069 0.613
MOD_NEK2_1 885 890 PF00069 0.307
MOD_NEK2_1 941 946 PF00069 0.423
MOD_NEK2_1 992 997 PF00069 0.488
MOD_NEK2_2 1107 1112 PF00069 0.629
MOD_NEK2_2 269 274 PF00069 0.421
MOD_OFUCOSY 141 147 PF10250 0.593
MOD_PIKK_1 1127 1133 PF00454 0.704
MOD_PIKK_1 12 18 PF00454 0.631
MOD_PIKK_1 1303 1309 PF00454 0.381
MOD_PIKK_1 1348 1354 PF00454 0.283
MOD_PIKK_1 156 162 PF00454 0.603
MOD_PIKK_1 5 11 PF00454 0.625
MOD_PIKK_1 623 629 PF00454 0.484
MOD_PK_1 1293 1299 PF00069 0.410
MOD_PK_1 292 298 PF00069 0.409
MOD_PK_1 639 645 PF00069 0.457
MOD_PK_1 839 845 PF00069 0.342
MOD_PKA_1 103 109 PF00069 0.597
MOD_PKA_1 1209 1215 PF00069 0.576
MOD_PKA_1 1551 1557 PF00069 0.381
MOD_PKA_1 172 178 PF00069 0.651
MOD_PKA_1 464 470 PF00069 0.432
MOD_PKA_1 67 73 PF00069 0.634
MOD_PKA_2 102 108 PF00069 0.664
MOD_PKA_2 1126 1132 PF00069 0.601
MOD_PKA_2 1133 1139 PF00069 0.578
MOD_PKA_2 1209 1215 PF00069 0.739
MOD_PKA_2 1303 1309 PF00069 0.309
MOD_PKA_2 1310 1316 PF00069 0.309
MOD_PKA_2 1459 1465 PF00069 0.309
MOD_PKA_2 1512 1518 PF00069 0.381
MOD_PKA_2 1551 1557 PF00069 0.309
MOD_PKA_2 172 178 PF00069 0.651
MOD_PKA_2 202 208 PF00069 0.528
MOD_PKA_2 284 290 PF00069 0.370
MOD_PKA_2 66 72 PF00069 0.620
MOD_PKB_1 837 845 PF00069 0.358
MOD_Plk_1 1020 1026 PF00069 0.579
MOD_Plk_1 116 122 PF00069 0.619
MOD_Plk_1 259 265 PF00069 0.398
MOD_Plk_1 367 373 PF00069 0.481
MOD_Plk_1 581 587 PF00069 0.545
MOD_Plk_4 1200 1206 PF00069 0.742
MOD_Plk_4 1382 1388 PF00069 0.413
MOD_Plk_4 1413 1419 PF00069 0.397
MOD_Plk_4 1557 1563 PF00069 0.440
MOD_Plk_4 259 265 PF00069 0.476
MOD_Plk_4 279 285 PF00069 0.268
MOD_Plk_4 299 305 PF00069 0.401
MOD_Plk_4 310 316 PF00069 0.415
MOD_Plk_4 322 328 PF00069 0.362
MOD_Plk_4 344 350 PF00069 0.326
MOD_Plk_4 466 472 PF00069 0.358
MOD_Plk_4 474 480 PF00069 0.421
MOD_Plk_4 568 574 PF00069 0.401
MOD_Plk_4 680 686 PF00069 0.506
MOD_Plk_4 698 704 PF00069 0.582
MOD_Plk_4 759 765 PF00069 0.363
MOD_Plk_4 785 791 PF00069 0.380
MOD_Plk_4 868 874 PF00069 0.597
MOD_Plk_4 885 891 PF00069 0.271
MOD_Plk_4 941 947 PF00069 0.422
MOD_ProDKin_1 1119 1125 PF00069 0.783
MOD_ProDKin_1 1181 1187 PF00069 0.709
MOD_ProDKin_1 1220 1226 PF00069 0.661
MOD_ProDKin_1 141 147 PF00069 0.686
MOD_ProDKin_1 1455 1461 PF00069 0.384
MOD_ProDKin_1 491 497 PF00069 0.542
MOD_ProDKin_1 933 939 PF00069 0.548
MOD_ProDKin_1 971 977 PF00069 0.451
MOD_SUMO_for_1 1422 1425 PF00179 0.381
MOD_SUMO_rev_2 1416 1424 PF00179 0.309
MOD_SUMO_rev_2 175 181 PF00179 0.642
MOD_SUMO_rev_2 416 425 PF00179 0.460
MOD_SUMO_rev_2 566 572 PF00179 0.461
MOD_SUMO_rev_2 61 66 PF00179 0.608
TRG_DiLeu_BaEn_1 152 157 PF01217 0.613
TRG_DiLeu_BaEn_1 1557 1562 PF01217 0.478
TRG_DiLeu_BaEn_1 185 190 PF01217 0.641
TRG_DiLeu_BaEn_1 747 752 PF01217 0.482
TRG_DiLeu_BaEn_1 987 992 PF01217 0.466
TRG_DiLeu_LyEn_5 747 752 PF01217 0.482
TRG_ENDOCYTIC_2 1318 1321 PF00928 0.339
TRG_ENDOCYTIC_2 242 245 PF00928 0.513
TRG_ENDOCYTIC_2 304 307 PF00928 0.500
TRG_ENDOCYTIC_2 327 330 PF00928 0.469
TRG_ENDOCYTIC_2 391 394 PF00928 0.450
TRG_ENDOCYTIC_2 409 412 PF00928 0.419
TRG_ENDOCYTIC_2 552 555 PF00928 0.400
TRG_ENDOCYTIC_2 556 559 PF00928 0.383
TRG_ENDOCYTIC_2 676 679 PF00928 0.542
TRG_ENDOCYTIC_2 851 854 PF00928 0.387
TRG_ENDOCYTIC_2 932 935 PF00928 0.613
TRG_ER_diArg_1 1551 1553 PF00400 0.358
TRG_ER_diArg_1 171 173 PF00400 0.662
TRG_ER_diArg_1 369 372 PF00400 0.434
TRG_ER_diArg_1 431 433 PF00400 0.409
TRG_ER_diArg_1 487 490 PF00400 0.565
TRG_ER_diArg_1 66 68 PF00400 0.564
TRG_ER_diArg_1 78 81 PF00400 0.587
TRG_ER_diArg_1 961 963 PF00400 0.576
TRG_ER_diArg_1 979 981 PF00400 0.349
TRG_ER_diArg_1 997 999 PF00400 0.415
TRG_NES_CRM1_1 294 309 PF08389 0.364
TRG_NES_CRM1_1 514 528 PF08389 0.340
TRG_NES_CRM1_1 82 94 PF08389 0.580
TRG_Pf-PMV_PEXEL_1 1015 1019 PF00026 0.475
TRG_Pf-PMV_PEXEL_1 1076 1081 PF00026 0.655
TRG_Pf-PMV_PEXEL_1 1447 1451 PF00026 0.381

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P883 Leptomonas seymouri 48% 100%
A0A3S7XAH3 Leishmania donovani 99% 100%
A4HNV1 Leishmania braziliensis 63% 99%
E9ASL1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
Q4Q1Y5 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS